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The map label for this gene is hmgA [H]

Identifier: 83719016

GI number: 83719016

Start: 1571201

End: 1572553

Strand: Direct

Name: hmgA [H]

Synonym: BTH_I1397

Alternate gene names: 83719016

Gene position: 1571201-1572553 (Clockwise)

Preceding gene: 83719999

Following gene: 83721225

Centisome position: 41.25

GC content: 67.33

Gene sequence:

>1353_bases
ATGGAGAGAACGACAATCATGACACTGGATTTTTCGAAACCGGGCGAAGCCGGCTATCAGAGCGGCTTCGCGAACGAATT
CGCGACCGAGGCGCTGCCGGGCGCGCTGCCGCACGCGCGCAACTCGCCGCAGCGCGCGCCGTACGGGCTCTACGCGGAGC
AGTTGTCCGGCACCGCGTTCACCGCGCCGCGCGGCCATAACCGCCGCTCGTGGCTGTACCGCATCCGGCCCGCCGCCGTG
CATCGGCCGTTCGAGCTCGTGTCCGGCGAGCGCCGGATCGTCGCCGATTTCGGCGATTCGGGCGACGTGCCGCCGACGCC
GCCGAACCAGTTGCGCTGGGACCCGCTGCCGATGCCCGCGCAGCCGACCGATTTCGTCGACGGCTGGGTGACGATGGCGG
GCAACGGCTCGGCCGCCGCGATGAGCGGCTGCGCGATCCATCTGTACGCGGCGAACCGCTCGATGCGCGAGCGCTTCTTC
TACAGCGCGGACGGCGAACTGCTGATCGTGCCGCAGGAAGGGCGGCTTTTCATCATGACGGAGCTCGGACGGCTCGACGT
CGAGCCGTTCGAGATCGCGGTGATTCCGCGCGGCGTGCGCTTCGCGGTCGCGCTGCCCGACGGGCGCGCGCGCGGCTATG
TCTGCGAGAACTTCGGCGCGCTGCTCAGGCTGCCGGATCTCGGGCCGATCGGCTCGAACGGCCTGGCGAATCCGCGCGAC
TTCCTGACGCCGAACGCGTCGTACGAGGATCGCGAAGGCGCGTTCGAGCTCGTCGCGAAGTTGAACGGCCGGCTCTGGCG
CGCGGACATCGACCATTCGCCGTTCGACGTCGTCGCATGGCACGGCAACTACGCGCCGTACAAGTACGACCTGCGTCACT
TCAACACGATCGGCTCGATCAGCTACGATCATCCGGACCCGTCGATCTTCCTCGTGCTGCAGTCGCAAAGCGATACGCCG
GGCGTCGACGCGATCGACTTCGTGATCTTCCCGCCGCGCTGGCTCGCGGCCGAGGATACGTTCCGCCCGCCGTGGTTCCA
CCGCAACGTCGCGAGCGAGTTCATGGGGCTCGTGCACGGCGTCTACGACGCGAAGGCGGAAGGCTTCGTGCCGGGCGGCG
CGAGCCTGCACAACTGCATGTCGGGCCACGGGCCGGATGCGGACACGTTCGAGAAGGCGTCGGCGATCGATACGTCGAGG
CCGAACAAGGTCGGCGACACGATGGCGTTCATGTTCGAGACCCGCACGCTGATCCGGCCGACGCGCTTCGCGCTCGATAC
CGCGCAACTGCAGGCGAACTACTTCGAATGCTGGCAAGGCCTCAAGAAACATTTCAATCCGGAGCAACGATGA

Upstream 100 bases:

>100_bases
TCACGCGGCGGCCGTGCCGGTGCTGTGCTCGGCCGTCTTCGTGATCGGCCTCGCGAGCGTGACGCGGCGGCGCGGCACGG
CCGCGCCGAACGTCGCTTGA

Downstream 100 bases:

>100_bases
GCGCTATTTCCGACGCGCTGCGCGCGAGCCTCGATCCTTCCCGCAAGAGCTGGCTCGATGCGGCGAACGACGCCGCGTGC
GACTTCCCGATCCAGAACCT

Product: homogentisate 1,2-dioxygenase

Products: NA

Alternate protein names: Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MERTTIMTLDFSKPGEAGYQSGFANEFATEALPGALPHARNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAV
HRPFELVSGERRIVADFGDSGDVPPTPPNQLRWDPLPMPAQPTDFVDGWVTMAGNGSAAAMSGCAIHLYAANRSMRERFF
YSADGELLIVPQEGRLFIMTELGRLDVEPFEIAVIPRGVRFAVALPDGRARGYVCENFGALLRLPDLGPIGSNGLANPRD
FLTPNASYEDREGAFELVAKLNGRLWRADIDHSPFDVVAWHGNYAPYKYDLRHFNTIGSISYDHPDPSIFLVLQSQSDTP
GVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGVYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASAIDTSR
PNKVGDTMAFMFETRTLIRPTRFALDTAQLQANYFECWQGLKKHFNPEQR

Sequences:

>Translated_450_residues
MERTTIMTLDFSKPGEAGYQSGFANEFATEALPGALPHARNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAV
HRPFELVSGERRIVADFGDSGDVPPTPPNQLRWDPLPMPAQPTDFVDGWVTMAGNGSAAAMSGCAIHLYAANRSMRERFF
YSADGELLIVPQEGRLFIMTELGRLDVEPFEIAVIPRGVRFAVALPDGRARGYVCENFGALLRLPDLGPIGSNGLANPRD
FLTPNASYEDREGAFELVAKLNGRLWRADIDHSPFDVVAWHGNYAPYKYDLRHFNTIGSISYDHPDPSIFLVLQSQSDTP
GVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGVYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASAIDTSR
PNKVGDTMAFMFETRTLIRPTRFALDTAQLQANYFECWQGLKKHFNPEQR
>Mature_450_residues
MERTTIMTLDFSKPGEAGYQSGFANEFATEALPGALPHARNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAV
HRPFELVSGERRIVADFGDSGDVPPTPPNQLRWDPLPMPAQPTDFVDGWVTMAGNGSAAAMSGCAIHLYAANRSMRERFF
YSADGELLIVPQEGRLFIMTELGRLDVEPFEIAVIPRGVRFAVALPDGRARGYVCENFGALLRLPDLGPIGSNGLANPRD
FLTPNASYEDREGAFELVAKLNGRLWRADIDHSPFDVVAWHGNYAPYKYDLRHFNTIGSISYDHPDPSIFLVLQSQSDTP
GVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGVYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASAIDTSR
PNKVGDTMAFMFETRTLIRPTRFALDTAQLQANYFECWQGLKKHFNPEQR

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

Organism=Homo sapiens, GI115527117, Length=444, Percent_Identity=52.027027027027, Blast_Score=457, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17507969, Length=435, Percent_Identity=51.9540229885057, Blast_Score=441, Evalue=1e-124,
Organism=Drosophila melanogaster, GI24583650, Length=439, Percent_Identity=51.0250569476082, Blast_Score=426, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR022950 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: =1.13.11.5 [H]

Molecular weight: Translated: 50014; Mature: 50014

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTTIMTLDFSKPGEAGYQSGFANEFATEALPGALPHARNSPQRAPYGLYAEQLSGTAF
CCCEEEEEEECCCCCCCHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEE
TAPRGHNRRSWLYRIRPAAVHRPFELVSGERRIVADFGDSGDVPPTPPNQLRWDPLPMPA
ECCCCCCCCCEEEEECHHHHCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
QPTDFVDGWVTMAGNGSAAAMSGCAIHLYAANRSMRERFFYSADGELLIVPQEGRLFIMT
CCCCCCCCEEEEECCCCCCEECCCEEEEEECCCHHHHHEEECCCCCEEEEECCCCEEEEE
ELGRLDVEPFEIAVIPRGVRFAVALPDGRARGYVCENFGALLRLPDLGPIGSNGLANPRD
ECCCCCCCCEEEEEECCCEEEEEECCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCHH
FLTPNASYEDREGAFELVAKLNGRLWRADIDHSPFDVVAWHGNYAPYKYDLRHFNTIGSI
HCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCEEECHHHCCCCCCC
SYDHPDPSIFLVLQSQSDTPGVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHG
EECCCCCEEEEEEECCCCCCCCCEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHH
VYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASAIDTSRPNKVGDTMAFMFETRTLIRP
HHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
TRFALDTAQLQANYFECWQGLKKHFNPEQR
HHHEEHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MERTTIMTLDFSKPGEAGYQSGFANEFATEALPGALPHARNSPQRAPYGLYAEQLSGTAF
CCCEEEEEEECCCCCCCHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEE
TAPRGHNRRSWLYRIRPAAVHRPFELVSGERRIVADFGDSGDVPPTPPNQLRWDPLPMPA
ECCCCCCCCCEEEEECHHHHCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
QPTDFVDGWVTMAGNGSAAAMSGCAIHLYAANRSMRERFFYSADGELLIVPQEGRLFIMT
CCCCCCCCEEEEECCCCCCEECCCEEEEEECCCHHHHHEEECCCCCEEEEECCCCEEEEE
ELGRLDVEPFEIAVIPRGVRFAVALPDGRARGYVCENFGALLRLPDLGPIGSNGLANPRD
ECCCCCCCCEEEEEECCCEEEEEECCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCHH
FLTPNASYEDREGAFELVAKLNGRLWRADIDHSPFDVVAWHGNYAPYKYDLRHFNTIGSI
HCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCEEECHHHCCCCCCC
SYDHPDPSIFLVLQSQSDTPGVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHG
EECCCCCEEEEEEECCCCCCCCCEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHH
VYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASAIDTSRPNKVGDTMAFMFETRTLIRP
HHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
TRFALDTAQLQANYFECWQGLKKHFNPEQR
HHHEEHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA