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The map label for this gene is pcaK [H]

Identifier: 83719999

GI number: 83719999

Start: 1569461

End: 1571200

Strand: Direct

Name: pcaK [H]

Synonym: BTH_I1396

Alternate gene names: 83719999

Gene position: 1569461-1571200 (Clockwise)

Preceding gene: 83720631

Following gene: 83719016

Centisome position: 41.2

GC content: 71.55

Gene sequence:

>1740_bases
ATGACGCGCGCCCCGGCACGTTCTATCTGCTGCGTCCGGACCAGCATGTGTGCGCGCGCTTTCGCACGGCGCAAGCGAGC
GCGGTGCGCGCGGCGCTCGCCCGCGCGATCTGCCGCGCGTGAGCGGAAAACCAACGAACGAGACCAGGAGACACCCGATG
CACCTCGACACCCGCTTGCGCCTGCCCGATCCGGACGCGTTCTACGAAGCGCTGATCGACATGCACCGCGATCTGCCCGA
CAGCGAGAGCCAGCTCGTCAACGCGAAGCTGATCCTGCTGCTCGCGAACCAGATCGGCGACCTCGACGTGCTGCGCGAAG
CGATGGCGCTCGCGCGCAGCGGCGCGGCCGTGCTCGAAGGCGCGCCCGGCGCGCCCGCGCTGCAATGAGCGCGGCGGCGA
GTGCCGCGCGCGTGCTCGAAGTTGAGCGCGTGATCGACGACACGCACCGGCCCGCGTTTCACGCGATGCTGCTCGCGCTG
TGCGGGCTGTGCCTCGTGATCGACGGTTTCGATGCGCAGGCGATGGGCTACGTCGCGCCGAGCGTGATCGCCGAGTGGGG
CGTGAAGAAGCAGGCGCTCGGGCCCGTCTTCAGCGCGAGCCTGTTCGGGATGCTGCTCGGCGCGCTCGGCCTGTCGGTGC
TCGCCGACCGGATCGGCCGGCGGCCGGTATTGATCGGCGCGACGCTGTTCTTCGCGCTGACGATGCTCGCGACGCCGTTC
GCGACATCGATTCCGACGCTGATCGCGCTGCGCTTCGTCACGGGCCTGGGGCTCGGCTGCATCATGCCGAACGCGATGGC
GCTCGTCGGTGAATGCAGCCCGGGCGCGCACCGCGTGAAGCGGATGATGATCGTGTCGTGCGGCTTCACGGCCGGCGCGG
CGCTGGGCGGCTTCGTCAGCGCGGCGCTGATTCCGGCGTTCGGCTGGCGCGCGGTGTTCTTCGTCGGCGGCGCGGTGCCG
CTCGCGCTCGCGGCCGCGATGGCCGCGCGCCTGCCCGAATCGCCGCAACTGCTCGTGCTGCGCGGCCGGCACGACGCGGC
GCGCGCGTGGCTCGCGAAGTTCGCGCCGCAGCTCGCGGTCTCGCCCGATACGCGGCTCGTCGTGCGCGAAGCGGGGCCGC
AGGGCGCGCCCGTCGCCGAGCTGTTCCGCTCGGGGCGCGCGAGCGTCACGCTGCTGCTCTGGGCGATCAACTTCATGAAC
CTGATCGACCTGTACTTCCTGTCGAACTGGCTGCCGACCGTGATGCGCGACGCGGGCTACGCGAGCGGCACGGCCGTCAT
CGTCGGCACCGTGCTGCAGACGGGCGGCGTGATCGGCACGCTGTCGCTCGGCCGGTTCATCGAACGGTACGGCTTCGTGC
GCGTGCTGTTCGCCTGCTTCGCGTGCGCGGCGATCGCGGTCGGCCTGATCGGCTCGGTCGCGCATGCGTTTTACTGGCTG
CTCGCAGCCGTGTTCGTCGGCGGCTTTTGCGTCGTTGGCGGACAGCCCGCGGTCAACGCGCTCGCGGGCCATTATTACCC
GACGTCGCTGCGCTCGACGGGCATCGGCTGGAGCCTCGGCGTGGGCCGCGTCGGCTCCGTGCTCGGGCCGCTCGTCGGCG
GGCAGCTGATCGCGCTCGGCTGGTCGAACGACGCGCTCTTTCACGCGGCGGCCGTGCCGGTGCTGTGCTCGGCCGTCTTC
GTGATCGGCCTCGCGAGCGTGACGCGGCGGCGCGGCACGGCCGCGCCGAACGTCGCTTGA

Upstream 100 bases:

>100_bases
CCGCCGGTCGCGCCCGTGCTCGTCGTGCCGAAGGGCGAGGCGCGCGCGGTCGAGGGCGTCGACGTGATCGAGGACAGCGA
AGGGCTCGCCGCGCAGCGCT

Downstream 100 bases:

>100_bases
ATGGAGAGAACGACAATCATGACACTGGATTTTTCGAAACCGGGCGAAGCCGGCTATCAGAGCGGCTTCGCGAACGAATT
CGCGACCGAGGCGCTGCCGG

Product: 4-hydroxybenzoate transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MTRAPARSICCVRTSMCARAFARRKRARCARRSPARSAARERKTNERDQETPDAPRHPLAPARSGRVLRSADRHAPRSAR
QREPARQREADPAAREPDRRPRRAARSDGARAQRRGRARRRARRARAAMSAAASAARVLEVERVIDDTHRPAFHAMLLAL
CGLCLVIDGFDAQAMGYVAPSVIAEWGVKKQALGPVFSASLFGMLLGALGLSVLADRIGRRPVLIGATLFFALTMLATPF
ATSIPTLIALRFVTGLGLGCIMPNAMALVGECSPGAHRVKRMMIVSCGFTAGAALGGFVSAALIPAFGWRAVFFVGGAVP
LALAAAMAARLPESPQLLVLRGRHDAARAWLAKFAPQLAVSPDTRLVVREAGPQGAPVAELFRSGRASVTLLLWAINFMN
LIDLYFLSNWLPTVMRDAGYASGTAVIVGTVLQTGGVIGTLSLGRFIERYGFVRVLFACFACAAIAVGLIGSVAHAFYWL
LAAVFVGGFCVVGGQPAVNALAGHYYPTSLRSTGIGWSLGVGRVGSVLGPLVGGQLIALGWSNDALFHAAAVPVLCSAVF
VIGLASVTRRRGTAAPNVA

Sequences:

>Translated_579_residues
MTRAPARSICCVRTSMCARAFARRKRARCARRSPARSAARERKTNERDQETPDAPRHPLAPARSGRVLRSADRHAPRSAR
QREPARQREADPAAREPDRRPRRAARSDGARAQRRGRARRRARRARAAMSAAASAARVLEVERVIDDTHRPAFHAMLLAL
CGLCLVIDGFDAQAMGYVAPSVIAEWGVKKQALGPVFSASLFGMLLGALGLSVLADRIGRRPVLIGATLFFALTMLATPF
ATSIPTLIALRFVTGLGLGCIMPNAMALVGECSPGAHRVKRMMIVSCGFTAGAALGGFVSAALIPAFGWRAVFFVGGAVP
LALAAAMAARLPESPQLLVLRGRHDAARAWLAKFAPQLAVSPDTRLVVREAGPQGAPVAELFRSGRASVTLLLWAINFMN
LIDLYFLSNWLPTVMRDAGYASGTAVIVGTVLQTGGVIGTLSLGRFIERYGFVRVLFACFACAAIAVGLIGSVAHAFYWL
LAAVFVGGFCVVGGQPAVNALAGHYYPTSLRSTGIGWSLGVGRVGSVLGPLVGGQLIALGWSNDALFHAAAVPVLCSAVF
VIGLASVTRRRGTAAPNVA
>Mature_578_residues
TRAPARSICCVRTSMCARAFARRKRARCARRSPARSAARERKTNERDQETPDAPRHPLAPARSGRVLRSADRHAPRSARQ
REPARQREADPAAREPDRRPRRAARSDGARAQRRGRARRRARRARAAMSAAASAARVLEVERVIDDTHRPAFHAMLLALC
GLCLVIDGFDAQAMGYVAPSVIAEWGVKKQALGPVFSASLFGMLLGALGLSVLADRIGRRPVLIGATLFFALTMLATPFA
TSIPTLIALRFVTGLGLGCIMPNAMALVGECSPGAHRVKRMMIVSCGFTAGAALGGFVSAALIPAFGWRAVFFVGGAVPL
ALAAAMAARLPESPQLLVLRGRHDAARAWLAKFAPQLAVSPDTRLVVREAGPQGAPVAELFRSGRASVTLLLWAINFMNL
IDLYFLSNWLPTVMRDAGYASGTAVIVGTVLQTGGVIGTLSLGRFIERYGFVRVLFACFACAAIAVGLIGSVAHAFYWLL
AAVFVGGFCVVGGQPAVNALAGHYYPTSLRSTGIGWSLGVGRVGSVLGPLVGGQLIALGWSNDALFHAAAVPVLCSAVFV
IGLASVTRRRGTAAPNVA

Specific function: Transporter for 4-hydroxybenzoate. Also required for chemotaxis to aromatic acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=421, Percent_Identity=24.7030878859857, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI166064021, Length=382, Percent_Identity=28.2722513089005, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI8923870, Length=373, Percent_Identity=27.6139410187668, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI7662270, Length=299, Percent_Identity=21.4046822742475, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI213021148, Length=441, Percent_Identity=23.1292517006803, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081723, Length=410, Percent_Identity=34.390243902439, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI87082231, Length=407, Percent_Identity=25.0614250614251, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788068, Length=398, Percent_Identity=24.6231155778894, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082404, Length=393, Percent_Identity=22.9007633587786, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786229, Length=393, Percent_Identity=21.1195928753181, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788074, Length=257, Percent_Identity=27.6264591439689, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87082159, Length=389, Percent_Identity=24.6786632390745, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=472, Percent_Identity=22.6694915254237, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640198, Length=575, Percent_Identity=22.4347826086957, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640196, Length=575, Percent_Identity=22.4347826086957, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640200, Length=575, Percent_Identity=22.4347826086957, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922874, Length=406, Percent_Identity=23.1527093596059, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161077756, Length=473, Percent_Identity=23.6786469344609, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922616, Length=420, Percent_Identity=23.3333333333333, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 61355; Mature: 61223

Theoretical pI: Translated: 12.01; Mature: 12.01

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAPARSICCVRTSMCARAFARRKRARCARRSPARSAARERKTNERDQETPDAPRHPLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
PARSGRVLRSADRHAPRSARQREPARQREADPAAREPDRRPRRAARSDGARAQRRGRARR
CCCCCCHHHHHHHCCCHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH
RARRARAAMSAAASAARVLEVERVIDDTHRPAFHAMLLALCGLCLVIDGFDAQAMGYVAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SVIAEWGVKKQALGPVFSASLFGMLLGALGLSVLADRIGRRPVLIGATLFFALTMLATPF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCH
ATSIPTLIALRFVTGLGLGCIMPNAMALVGECSPGAHRVKRMMIVSCGFTAGAALGGFVS
HHHHHHHHHHHHHHHCCHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AALIPAFGWRAVFFVGGAVPLALAAAMAARLPESPQLLVLRGRHDAARAWLAKFAPQLAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCC
SPDTRLVVREAGPQGAPVAELFRSGRASVTLLLWAINFMNLIDLYFLSNWLPTVMRDAGY
CCCCEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASGTAVIVGTVLQTGGVIGTLSLGRFIERYGFVRVLFACFACAAIAVGLIGSVAHAFYWL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAVFVGGFCVVGGQPAVNALAGHYYPTSLRSTGIGWSLGVGRVGSVLGPLVGGQLIALG
HHHHHHCCEEEECCCHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
WSNDALFHAAAVPVLCSAVFVIGLASVTRRRGTAAPNVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRAPARSICCVRTSMCARAFARRKRARCARRSPARSAARERKTNERDQETPDAPRHPLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
PARSGRVLRSADRHAPRSARQREPARQREADPAAREPDRRPRRAARSDGARAQRRGRARR
CCCCCCHHHHHHHCCCHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH
RARRARAAMSAAASAARVLEVERVIDDTHRPAFHAMLLALCGLCLVIDGFDAQAMGYVAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SVIAEWGVKKQALGPVFSASLFGMLLGALGLSVLADRIGRRPVLIGATLFFALTMLATPF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCH
ATSIPTLIALRFVTGLGLGCIMPNAMALVGECSPGAHRVKRMMIVSCGFTAGAALGGFVS
HHHHHHHHHHHHHHHCCHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AALIPAFGWRAVFFVGGAVPLALAAAMAARLPESPQLLVLRGRHDAARAWLAKFAPQLAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCC
SPDTRLVVREAGPQGAPVAELFRSGRASVTLLLWAINFMNLIDLYFLSNWLPTVMRDAGY
CCCCEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASGTAVIVGTVLQTGGVIGTLSLGRFIERYGFVRVLFACFACAAIAVGLIGSVAHAFYWL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAVFVGGFCVVGGQPAVNALAGHYYPTSLRSTGIGWSLGVGRVGSVLGPLVGGQLIALG
HHHHHHCCEEEECCCHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
WSNDALFHAAAVPVLCSAVFVIGLASVTRRRGTAAPNVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961399 [H]