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The map label for this gene is maeB [H]

Identifier: 83718682

GI number: 83718682

Start: 1334021

End: 1336327

Strand: Direct

Name: maeB [H]

Synonym: BTH_I1189

Alternate gene names: 83718682

Gene position: 1334021-1336327 (Clockwise)

Preceding gene: 83720046

Following gene: 83718400

Centisome position: 35.02

GC content: 65.41

Gene sequence:

>2307_bases
ATGTCCACCTCGTCCTCCTCCTCATCGAAAGATAAACTCCGCGAAGCCGCTCTCGATTACCACGAATTCCCGACGCCGGG
CAAAGTCGCGATCGCGCCGACCAAACAGATGATCAACCAGCGCGATCTCGCGCTCGCTTATTCGCCGGGCGTCGCGTTCG
CGTGCGAGGAGATCGTCGAGAATCCGCTGAACGCCGCGCGCTTCACCGCGCGCAGCAACCTCGTCGGCGTCGTGACGAAC
GGCACCGCGGTGCTCGGCCTCGGCAACATCGGCCCGCTCGCGTCGAAGCCGGTGATGGAAGGCAAGGCGGTGCTCTTCAA
GAAGTTCGCCGGGATCGACGTGTTCGACATCGAGCTCAACGAGTCCGATCCGCACAAGCTCGTCGACGTGATCGCCGCGC
TCGAGCCGACGTTCGGCGGGATCAACCTCGAGGACATCAAGGCGCCGGACTGCTTCATCGTCGAGCGCGAATGCCGCAAG
CGCATGAAGATCCCGGTGTTCCACGACGACCAGCACGGCACGGCGATCGTCGTCGCGGCGGCGGTCACGAACGGGCTGAA
AGTGGTCGGCAAGAGCATCAAGGAGGTGAAGCTCGTCGCGTCGGGCGCGGGCGCGGCGGCGCTCGCGTGCCTTGATTTGC
TCGTCGATCTCGGCCTACCGCTCGAGAACATCACGGTGACGGACCTCGCGGGCGTCGTCTATAAGGGCCGCACCGAGCTG
ATGGACCCGGACAAGGAGCGTTTCGCGCGCGAAACCGATGCGCGCACGCTGTCGGAAGTGATCGGCGGCGCGGATATCTT
CCTCGGCCTGTCGGCGGCCGGCGTGCTGAAGGCCGACATGGTGAAGACGATGGCCGCGCGCCCGCTGATTCTCGCGCTCG
CGAATCCGACCCCTGAAATCCTGCCGGAAGTGGCGCTCGAGGCTCGCCCGGACGCGGTGCTCGCGACGGGCCGCACCGAC
TACCCGAACCAGGTCAACAACGTCCTGTGCTTCCCGTTCATTTTCCGCGGCGCGCTCGACGTGGGCGCGACGACGATCAC
CCGCGAGATGGAGATCGCCGCCGTCAACGCGATCGCCGAGCTCGCGCAACACGAGCAGAGCGACATCGTCGCGACCGCGT
ACGGTATCCAGGATCTGTCGTTCGGTCCGGAATATCTGATTCCGAAGCCGTTCGATCCGCGCCTCATCGTGAAGATTGCG
CCCGCGGTCGCGCAGGCGGCGATGGACGGCGGCGTCGCAACCCGTCCGATCGAGGACATGGAGGCGTACAAGGTTCATCT
GCAACAGTTCGTCTATCACAGCGGCACGACGATGAAGCCGGTGTTCCAGATCGCGCGCAGCGCGCCCGCCGAGAAGAAGC
GGGTCGTGTTCGCGGAGGGCGAGGAGGAGCGCGTGCTGCGCGCGGTGCAGATCGTCGTCGACGAGAAGCTCGCGAAGCCG
ATCCTCATCGGTCGACCCGCCGTGATCGAGCACCGTATCCAGCGCTACGGCCTGCGTCTCACGCCGGGCGTCGATTTCAC
GATCGTCAACACCGAGCACGACGAGCGTTACCGCGATTTCTGGCAAACCTACTTCAAGATGATGGCCCGCAAGGGGATCA
GCGAGCAGCTCGCGCGCGTGGAGATGCGCCGCCGCACGACGCTGATCGGCTCGATGCTCGTCAAGAAGGGCGAAGCGGAC
GGGATGATCTGCGGCACGATCAGCACGACGCACCGCCACCTGCACTTCATTGATCAGGTGATCGGCAAGCGCGCCGGCTG
CAGCGTCTATGGCGCGATGAACGCGCTCGTGCTGCCCGGCCGCCAGATTTTCCTCGTCGACACGCACGTGAACGTCGATC
CGACCCCGGCGCAACTGGCCGAAATCACGATCATGGCGGCGGAGGAAGTGCGCCGCTTCGGCATCGAGCCGAAGGTCGCG
CTGCTGTCTCACTCGAACTTCGGCACGAGCAATGCGCCTTCCGCGCAGAAGATGCGCGATACGCTCGCGATCCTGCACGA
ACGCGCGCCGGAGCTGCAAGTCGACGGCGAGATGCACGGCGATGTCGCGCTCGACGCCGCGCTGCGCAAGGAGATCCTGC
CCGAATCGACGCTCGAGGGCGAAGCGAACCTGCTCGTGCTGCCGAACATCGATGCGGCGAACATCGCGTACAACCTGTTG
AAGACGGCGGCCGGCAACAACATCGCGATCGGGCCGATTCTGCTCGGCGCCGCGCAGCCCGTGCATGTGCTGACCGAATC
GGCGACCGTGCGCCGGATCGTCAACATGACGGCGCTGCTGGTTGCCGACGTGAACGCAGCGCGTTGA

Upstream 100 bases:

>100_bases
GGTCGCGGCTGTCGAACCCTAATCGGCGATTTTACGTGTGGGATTGGCGCTACAATGCGTCGAACAGGTATTCTAATCCG
CAGACCCCCCGTAGAGACAC

Downstream 100 bases:

>100_bases
GCGAAGTTATCGAACGATAAAAAAACGGCGCGCCCATTGCGGGCGCGCCGTCGGGCATGGCGGAGATAAGCGCCTTCCCG
AAGCCGACGACGCCACCCTT

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 768; Mature: 767

Protein sequence:

>768_residues
MSTSSSSSSKDKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARFTARSNLVGVVTN
GTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVERECRK
RMKIPVFHDDQHGTAIVVAAAVTNGLKVVGKSIKEVKLVASGAGAAALACLDLLVDLGLPLENITVTDLAGVVYKGRTEL
MDPDKERFARETDARTLSEVIGGADIFLGLSAAGVLKADMVKTMAARPLILALANPTPEILPEVALEARPDAVLATGRTD
YPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQHEQSDIVATAYGIQDLSFGPEYLIPKPFDPRLIVKIA
PAVAQAAMDGGVATRPIEDMEAYKVHLQQFVYHSGTTMKPVFQIARSAPAEKKRVVFAEGEEERVLRAVQIVVDEKLAKP
ILIGRPAVIEHRIQRYGLRLTPGVDFTIVNTEHDERYRDFWQTYFKMMARKGISEQLARVEMRRRTTLIGSMLVKKGEAD
GMICGTISTTHRHLHFIDQVIGKRAGCSVYGAMNALVLPGRQIFLVDTHVNVDPTPAQLAEITIMAAEEVRRFGIEPKVA
LLSHSNFGTSNAPSAQKMRDTLAILHERAPELQVDGEMHGDVALDAALRKEILPESTLEGEANLLVLPNIDAANIAYNLL
KTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMTALLVADVNAAR

Sequences:

>Translated_768_residues
MSTSSSSSSKDKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARFTARSNLVGVVTN
GTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVERECRK
RMKIPVFHDDQHGTAIVVAAAVTNGLKVVGKSIKEVKLVASGAGAAALACLDLLVDLGLPLENITVTDLAGVVYKGRTEL
MDPDKERFARETDARTLSEVIGGADIFLGLSAAGVLKADMVKTMAARPLILALANPTPEILPEVALEARPDAVLATGRTD
YPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQHEQSDIVATAYGIQDLSFGPEYLIPKPFDPRLIVKIA
PAVAQAAMDGGVATRPIEDMEAYKVHLQQFVYHSGTTMKPVFQIARSAPAEKKRVVFAEGEEERVLRAVQIVVDEKLAKP
ILIGRPAVIEHRIQRYGLRLTPGVDFTIVNTEHDERYRDFWQTYFKMMARKGISEQLARVEMRRRTTLIGSMLVKKGEAD
GMICGTISTTHRHLHFIDQVIGKRAGCSVYGAMNALVLPGRQIFLVDTHVNVDPTPAQLAEITIMAAEEVRRFGIEPKVA
LLSHSNFGTSNAPSAQKMRDTLAILHERAPELQVDGEMHGDVALDAALRKEILPESTLEGEANLLVLPNIDAANIAYNLL
KTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMTALLVADVNAAR
>Mature_767_residues
STSSSSSSKDKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARFTARSNLVGVVTNG
TAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVERECRKR
MKIPVFHDDQHGTAIVVAAAVTNGLKVVGKSIKEVKLVASGAGAAALACLDLLVDLGLPLENITVTDLAGVVYKGRTELM
DPDKERFARETDARTLSEVIGGADIFLGLSAAGVLKADMVKTMAARPLILALANPTPEILPEVALEARPDAVLATGRTDY
PNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQHEQSDIVATAYGIQDLSFGPEYLIPKPFDPRLIVKIAP
AVAQAAMDGGVATRPIEDMEAYKVHLQQFVYHSGTTMKPVFQIARSAPAEKKRVVFAEGEEERVLRAVQIVVDEKLAKPI
LIGRPAVIEHRIQRYGLRLTPGVDFTIVNTEHDERYRDFWQTYFKMMARKGISEQLARVEMRRRTTLIGSMLVKKGEADG
MICGTISTTHRHLHFIDQVIGKRAGCSVYGAMNALVLPGRQIFLVDTHVNVDPTPAQLAEITIMAAEEVRRFGIEPKVAL
LSHSNFGTSNAPSAQKMRDTLAILHERAPELQVDGEMHGDVALDAALRKEILPESTLEGEANLLVLPNIDAANIAYNLLK
TAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMTALLVADVNAAR

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4505143, Length=345, Percent_Identity=26.3768115942029, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI62420882, Length=344, Percent_Identity=28.1976744186047, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI62420880, Length=344, Percent_Identity=28.1976744186047, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI239049447, Length=344, Percent_Identity=28.1976744186047, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI4505145, Length=405, Percent_Identity=27.9012345679012, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI270265879, Length=368, Percent_Identity=28.804347826087, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI1788806, Length=754, Percent_Identity=62.0689655172414, Blast_Score=969, Evalue=0.0,
Organism=Escherichia coli, GI1788635, Length=319, Percent_Identity=32.2884012539185, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788800, Length=326, Percent_Identity=31.5950920245399, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17537199, Length=464, Percent_Identity=25.6465517241379, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281362672, Length=482, Percent_Identity=26.3485477178423, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281362674, Length=482, Percent_Identity=26.3485477178423, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356279, Length=482, Percent_Identity=26.3485477178423, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78707242, Length=408, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI78707238, Length=408, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI78707240, Length=349, Percent_Identity=26.9340974212034, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 82994; Mature: 82863

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSSSSSSKDKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYSPGVAFACEEIVE
CCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCEEEEECCCHHHHHHHHHH
NPLNAARFTARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELN
CCCHHHHHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEC
ESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVERECRKRMKIPVFHDDQHGTAIVVAA
CCCHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHHCCCCCEEECCCCCCEEEEEE
AVTNGLKVVGKSIKEVKLVASGAGAAALACLDLLVDLGLPLENITVTDLAGVVYKGRTEL
HHHCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCHHC
MDPDKERFARETDARTLSEVIGGADIFLGLSAAGVLKADMVKTMAARPLILALANPTPEI
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCHHH
LPEVALEARPDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAE
HHHHHHCCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LAQHEQSDIVATAYGIQDLSFGPEYLIPKPFDPRLIVKIAPAVAQAAMDGGVATRPIEDM
HHHCCCCCEEEEEECCEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHCCCCCCCCHHHH
EAYKVHLQQFVYHSGTTMKPVFQIARSAPAEKKRVVFAEGEEERVLRAVQIVVDEKLAKP
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
ILIGRPAVIEHRIQRYGLRLTPGVDFTIVNTEHDERYRDFWQTYFKMMARKGISEQLARV
EEECCCHHHHHHHHHCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
EMRRRTTLIGSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRAGCSVYGAMNALVLPG
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEECC
RQIFLVDTHVNVDPTPAQLAEITIMAAEEVRRFGIEPKVALLSHSNFGTSNAPSAQKMRD
CEEEEEEEECCCCCCHHHHHHEEEEEHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHH
TLAILHERAPELQVDGEMHGDVALDAALRKEILPESTLEGEANLLVLPNIDAANIAYNLL
HHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHH
KTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMTALLVADVNAAR
HHCCCCCEEECCEEECCCCCHHHHHCHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
STSSSSSSKDKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYSPGVAFACEEIVE
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCEEEEECCCHHHHHHHHHH
NPLNAARFTARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELN
CCCHHHHHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEC
ESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVERECRKRMKIPVFHDDQHGTAIVVAA
CCCHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHHCCCCCEEECCCCCCEEEEEE
AVTNGLKVVGKSIKEVKLVASGAGAAALACLDLLVDLGLPLENITVTDLAGVVYKGRTEL
HHHCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCHHC
MDPDKERFARETDARTLSEVIGGADIFLGLSAAGVLKADMVKTMAARPLILALANPTPEI
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCHHH
LPEVALEARPDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAE
HHHHHHCCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LAQHEQSDIVATAYGIQDLSFGPEYLIPKPFDPRLIVKIAPAVAQAAMDGGVATRPIEDM
HHHCCCCCEEEEEECCEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHCCCCCCCCHHHH
EAYKVHLQQFVYHSGTTMKPVFQIARSAPAEKKRVVFAEGEEERVLRAVQIVVDEKLAKP
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
ILIGRPAVIEHRIQRYGLRLTPGVDFTIVNTEHDERYRDFWQTYFKMMARKGISEQLARV
EEECCCHHHHHHHHHCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
EMRRRTTLIGSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRAGCSVYGAMNALVLPG
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEECC
RQIFLVDTHVNVDPTPAQLAEITIMAAEEVRRFGIEPKVALLSHSNFGTSNAPSAQKMRD
CEEEEEEEECCCCCCHHHHHHEEEEEHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHH
TLAILHERAPELQVDGEMHGDVALDAALRKEILPESTLEGEANLLVLPNIDAANIAYNLL
HHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHH
KTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMTALLVADVNAAR
HHCCCCCEEECCEEECCCCCHHHHHCHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]