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The map label for this gene is aroK

Identifier: 83590399

GI number: 83590399

Start: 1599500

End: 1600021

Strand: Reverse

Name: aroK

Synonym: Moth_1556

Alternate gene names: 83590399

Gene position: 1600021-1599500 (Counterclockwise)

Preceding gene: 83590400

Following gene: 83590398

Centisome position: 60.87

GC content: 63.6

Gene sequence:

>522_bases
ATGCCGGGGAACATCGTCCTGATCGGTTTTATGGGCAGCGGTAAGACGACCGTCGGCCGGCTCCTGGCCCGGGATCTGGG
GTGGAGCTTCCTGGACACCGATACCATGGTTGAGGAACGCTTGGGCCTGCCCGTAAAAGAGATCTTTGCCCGGGAAGGGG
AGGAGTTTTTCCGGGAAGTAGAAAAAGAAGCCGTCGCCCGGGTGGCGACCGCCCGGCAGGCAGTTATTGCCACCGGCGGG
GGGGCGGTCCTTTGCGGGGTCAACGTCAAGTTGCTGCGGGAGGGCAACAAGGTCGTCTGGCTTCAGGTGCGGCCGGAGAC
GGCCCTCAAACGGGCCGGGCTGGACGACAGCCGTCCCCTACTCCAGGGGCGGGAACCACGGGACATCGCCGCCCTCCTCC
GGCGCCGGGAGCCCTATTATGCCTTCGCTGATATCTATATCGATACCGACGGTAAGGAGGCGGCCGCCGTGGCGCGGGAA
ATAAAGGAGGCTTTAAAGGCGTGGCTGGAGAGCTTAACGTAG

Upstream 100 bases:

>100_bases
ATCCAGGAACGCCTGGCTGCCTACCGGCAGTACCTGCAGGAAATTTGAGACTGAATTCAATTGAATTGACATTTCTTGCT
AACAGAAGGGGTGAGGAAGG

Downstream 100 bases:

>100_bases
ACCTGGGCGAGCGAACTTATAAAATCCACTGCGGCTCCGGATTGCTGCCGGTGGCAGGTTCCATCTTGCGTAATCTTAAT
CTGGCAGCCCCCTGCCTGGT

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MPGNIVLIGFMGSGKTTVGRLLARDLGWSFLDTDTMVEERLGLPVKEIFAREGEEFFREVEKEAVARVATARQAVIATGG
GAVLCGVNVKLLREGNKVVWLQVRPETALKRAGLDDSRPLLQGREPRDIAALLRRREPYYAFADIYIDTDGKEAAAVARE
IKEALKAWLESLT

Sequences:

>Translated_173_residues
MPGNIVLIGFMGSGKTTVGRLLARDLGWSFLDTDTMVEERLGLPVKEIFAREGEEFFREVEKEAVARVATARQAVIATGG
GAVLCGVNVKLLREGNKVVWLQVRPETALKRAGLDDSRPLLQGREPRDIAALLRRREPYYAFADIYIDTDGKEAAAVARE
IKEALKAWLESLT
>Mature_172_residues
PGNIVLIGFMGSGKTTVGRLLARDLGWSFLDTDTMVEERLGLPVKEIFAREGEEFFREVEKEAVARVATARQAVIATGGG
AVLCGVNVKLLREGNKVVWLQVRPETALKRAGLDDSRPLLQGREPRDIAALLRRREPYYAFADIYIDTDGKEAAAVAREI
KEALKAWLESLT

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=167, Percent_Identity=38.9221556886228, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786587, Length=170, Percent_Identity=37.0588235294118, Blast_Score=77, Evalue=6e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_MOOTA (Q2RI74)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430408.1
- ProteinModelPortal:   Q2RI74
- SMR:   Q2RI74
- STRING:   Q2RI74
- GeneID:   3832189
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1556
- NMPDR:   fig|264732.9.peg.1560
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- PhylomeDB:   Q2RI74
- BioCyc:   MTHE264732:MOTH_1556-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 19114; Mature: 18983

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 34-34 BINDING 58-58 BINDING 80-80 BINDING 118-118 BINDING 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGNIVLIGFMGSGKTTVGRLLARDLGWSFLDTDTMVEERLGLPVKEIFAREGEEFFREV
CCCCEEEEEEECCCCHHHHHHHHHHHCCCHHCHHHHHHHHHCCCHHHHHHCCHHHHHHHH
EKEAVARVATARQAVIATGGGAVLCGVNVKLLREGNKVVWLQVRPETALKRAGLDDSRPL
HHHHHHHHHHHHHHEEEECCCEEEECCCEEEEECCCEEEEEEECCHHHHHHCCCCCCCCC
LQGREPRDIAALLRRREPYYAFADIYIDTDGKEAAAVAREIKEALKAWLESLT
CCCCCCHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGNIVLIGFMGSGKTTVGRLLARDLGWSFLDTDTMVEERLGLPVKEIFAREGEEFFREV
CCCEEEEEEECCCCHHHHHHHHHHHCCCHHCHHHHHHHHHCCCHHHHHHCCHHHHHHHH
EKEAVARVATARQAVIATGGGAVLCGVNVKLLREGNKVVWLQVRPETALKRAGLDDSRPL
HHHHHHHHHHHHHHEEEECCCEEEECCCEEEEECCCEEEEEEECCHHHHHHCCCCCCCCC
LQGREPRDIAALLRRREPYYAFADIYIDTDGKEAAAVAREIKEALKAWLESLT
CCCCCCHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA