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The map label for this gene is aroC

Identifier: 83590400

GI number: 83590400

Start: 1600074

End: 1601225

Strand: Reverse

Name: aroC

Synonym: Moth_1557

Alternate gene names: 83590400

Gene position: 1601225-1600074 (Counterclockwise)

Preceding gene: 83590401

Following gene: 83590399

Centisome position: 60.91

GC content: 67.45

Gene sequence:

>1152_bases
ATGCTGCGCTATCTGACTGCCGGGGAATCCCACGGCCGGGGCCTGAGCGTCATTGTCGAAGGGCTGCCGGCCGGGGTGCC
CCTGACAGATGGAGACATAAATACCTGGCTGACCCGCCGCCAGGGGGGATATGGCCGCGGCGGCCGCATGGCCATTGAAC
GGGATCAGGCCGAGATCCTGGCCGGGGTGCGCGGTGGCCTGACCCTGGGCAGTCCTATAGCCCTCTTCATCGCCAACCGG
GACTGGGAGAACTGGCAGGAGATCATGGCCCCGGGACCGGAAGCCAGGGCCGCCCGGGTAGTAACCCGACCGCGGCCGGG
ACATGCCGACCTGGCGGGAGGATTGAAATACCACCAGGCGGACCTGCGCAATATCCTGGAGCGGGCCAGCGCCCGGGAAA
CGGCGGCCAGGGTGGCCGCCGGGGCGGTGGCGGCAGTGCTGCTCAAAGAATTAGCCATTGAACTGGCCTTCCACGTCGTG
CGGATCGGGCCCGTAGAGGTCCGGGAGCAGGTGGATTGGGAGGCCGCCTGCCGGGCCGTCGAGTCACCGGTCTACTGCGC
TGACCCGGAAGCGGGCCGGGCCATGGTGGCGGCCATTGAAGAAGCACGACAGCAGGGAGATACCCTGGGAGGGGTAGTCG
AGGTCCTGGCCCGGGGCGTTCCTGCCGGCCTGGGCAGTCATGTCCACTGGGACCGGCGCCTGGACGGCCGCCTGGCCCAG
GCGCTCATGAGCATCCCGGCCATCAAAGGAGTTGAGATCGGCGCCGGCTTCAGGGTGGCTGCCCTGCCGGGGAGCCGGGC
CCACGACGCCATTGCCTACCGCAAGGGGCAGGGCTTCTATCATCCTACCAACCGGGCCGGCGGCCTGGAAGGCGGCCTGA
CCAATGGCGAAACCCTCGTCCTGCGAGCAGCCATGAAACCCATTCCCACCCTAATGCACCCACTGCCCAGCGTCGATTTG
GTCACCAAACAACCGGCGACAGCCAGCATCGAGCGTTCCGATGTCTGCGCCGTTCCGGCGGCGGCGGTGGTAGCCGCGGC
AGCGGTGGCCTGGGTCCTGGCCGGGGCTATACTGGAACAATTCGGGGGCGACTATTTACCGGTCATCCAGGAACGCCTGG
CTGCCTACCGGCAGTACCTGCAGGAAATTTGA

Upstream 100 bases:

>100_bases
CCCGGTAGCAGTCATGGACAGGGTCCTCCGGGAGGCCATGGGGGCGAGTTCAGGCGGGCCTGCTGCCGGCCGGTGAAAGC
TTGAGAAAGGATGGATACAT

Downstream 100 bases:

>100_bases
GACTGAATTCAATTGAATTGACATTTCTTGCTAACAGAAGGGGTGAGGAAGGATGCCGGGGAACATCGTCCTGATCGGTT
TTATGGGCAGCGGTAAGACG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MLRYLTAGESHGRGLSVIVEGLPAGVPLTDGDINTWLTRRQGGYGRGGRMAIERDQAEILAGVRGGLTLGSPIALFIANR
DWENWQEIMAPGPEARAARVVTRPRPGHADLAGGLKYHQADLRNILERASARETAARVAAGAVAAVLLKELAIELAFHVV
RIGPVEVREQVDWEAACRAVESPVYCADPEAGRAMVAAIEEARQQGDTLGGVVEVLARGVPAGLGSHVHWDRRLDGRLAQ
ALMSIPAIKGVEIGAGFRVAALPGSRAHDAIAYRKGQGFYHPTNRAGGLEGGLTNGETLVLRAAMKPIPTLMHPLPSVDL
VTKQPATASIERSDVCAVPAAAVVAAAAVAWVLAGAILEQFGGDYLPVIQERLAAYRQYLQEI

Sequences:

>Translated_383_residues
MLRYLTAGESHGRGLSVIVEGLPAGVPLTDGDINTWLTRRQGGYGRGGRMAIERDQAEILAGVRGGLTLGSPIALFIANR
DWENWQEIMAPGPEARAARVVTRPRPGHADLAGGLKYHQADLRNILERASARETAARVAAGAVAAVLLKELAIELAFHVV
RIGPVEVREQVDWEAACRAVESPVYCADPEAGRAMVAAIEEARQQGDTLGGVVEVLARGVPAGLGSHVHWDRRLDGRLAQ
ALMSIPAIKGVEIGAGFRVAALPGSRAHDAIAYRKGQGFYHPTNRAGGLEGGLTNGETLVLRAAMKPIPTLMHPLPSVDL
VTKQPATASIERSDVCAVPAAAVVAAAAVAWVLAGAILEQFGGDYLPVIQERLAAYRQYLQEI
>Mature_383_residues
MLRYLTAGESHGRGLSVIVEGLPAGVPLTDGDINTWLTRRQGGYGRGGRMAIERDQAEILAGVRGGLTLGSPIALFIANR
DWENWQEIMAPGPEARAARVVTRPRPGHADLAGGLKYHQADLRNILERASARETAARVAAGAVAAVLLKELAIELAFHVV
RIGPVEVREQVDWEAACRAVESPVYCADPEAGRAMVAAIEEARQQGDTLGGVVEVLARGVPAGLGSHVHWDRRLDGRLAQ
ALMSIPAIKGVEIGAGFRVAALPGSRAHDAIAYRKGQGFYHPTNRAGGLEGGLTNGETLVLRAAMKPIPTLMHPLPSVDL
VTKQPATASIERSDVCAVPAAAVVAAAAVAWVLAGAILEQFGGDYLPVIQERLAAYRQYLQEI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=363, Percent_Identity=38.2920110192837, Blast_Score=184, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=34.7480106100796, Blast_Score=191, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_MOOTA (Q2RI73)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430409.1
- HSSP:   P63611
- ProteinModelPortal:   Q2RI73
- SMR:   Q2RI73
- STRING:   Q2RI73
- GeneID:   3832190
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1557
- NMPDR:   fig|264732.9.peg.1561
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   MTHE264732:MOTH_1557-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 40608; Mature: 40608

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRYLTAGESHGRGLSVIVEGLPAGVPLTDGDINTWLTRRQGGYGRGGRMAIERDQAEIL
CCEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEHHHHHHH
AGVRGGLTLGSPIALFIANRDWENWQEIMAPGPEARAARVVTRPRPGHADLAGGLKYHQA
HHHCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHEEECCCCCCCHHHCCHHHHHH
DLRNILERASARETAARVAAGAVAAVLLKELAIELAFHVVRIGPVEVREQVDWEAACRAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHH
ESPVYCADPEAGRAMVAAIEEARQQGDTLGGVVEVLARGVPAGLGSHVHWDRRLDGRLAQ
CCCCEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
ALMSIPAIKGVEIGAGFRVAALPGSRAHDAIAYRKGQGFYHPTNRAGGLEGGLTNGETLV
HHHHCCCCCCEEECCCEEEEECCCCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCCEEE
LRAAMKPIPTLMHPLPSVDLVTKQPATASIERSDVCAVPAAAVVAAAAVAWVLAGAILEQ
EHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FGGDYLPVIQERLAAYRQYLQEI
HCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLRYLTAGESHGRGLSVIVEGLPAGVPLTDGDINTWLTRRQGGYGRGGRMAIERDQAEIL
CCEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEHHHHHHH
AGVRGGLTLGSPIALFIANRDWENWQEIMAPGPEARAARVVTRPRPGHADLAGGLKYHQA
HHHCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHEEECCCCCCCHHHCCHHHHHH
DLRNILERASARETAARVAAGAVAAVLLKELAIELAFHVVRIGPVEVREQVDWEAACRAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHH
ESPVYCADPEAGRAMVAAIEEARQQGDTLGGVVEVLARGVPAGLGSHVHWDRRLDGRLAQ
CCCCEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
ALMSIPAIKGVEIGAGFRVAALPGSRAHDAIAYRKGQGFYHPTNRAGGLEGGLTNGETLV
HHHHCCCCCCEEECCCEEEEECCCCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCCEEE
LRAAMKPIPTLMHPLPSVDLVTKQPATASIERSDVCAVPAAAVVAAAAVAWVLAGAILEQ
EHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FGGDYLPVIQERLAAYRQYLQEI
HCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA