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The map label for this gene is tcrA [H]

Identifier: 83590322

GI number: 83590322

Start: 1526259

End: 1526981

Strand: Reverse

Name: tcrA [H]

Synonym: Moth_1478

Alternate gene names: 83590322

Gene position: 1526981-1526259 (Counterclockwise)

Preceding gene: 83590323

Following gene: 83590321

Centisome position: 58.09

GC content: 58.51

Gene sequence:

>723_bases
ATGGGGAGACCGGCTGCAAGCCTTTGGGTACCAGGCGGCGATATGCGGATCCTGGTCGTTGAGGACGAAACCACCCTGGC
CAATACCCTGGCCCGTTGCCTGCGGGAGGAAGGATACGCCACCGACATTGCCTACGACGGCGAAGAGGGGGTCGCCTTCG
CGGAAACAGTGGTCTATGATTTGATAATTTTGGACCTCATGCTGCCCCGGCTGGATGGCATGGAAGTTATCCGGCGCCTG
CGGAATGAACGCATTGAGACCCCGGTCCTTATGCTGACGGCCCGGGATACGGTGGCCGACAAGGTCAGAGGACTGGATGC
CGGCGCCGACGATTACCTCACCAAGCCCTTTGCCCTGGCTGAACTCCTGGCCCGGGTCCGGGCCCTGCTGCGGCGGGAAA
GCGACAATAAGAGCACTGTCCTGCAGGTCGGGGACCTGGTGATGGACACGGTGTCCCGCCAGGTACGCCGGGGCGACCGG
GAAATTAACCTTACTAATAAGGAATACGCCCTGCTGGAGTACTTGATGCGCAATCCCAACCGGGTCCTGACCCGCACCCA
GATAGCCGAACACGTCTGGGATTATGATTTCAGCGGCATGTCCAATATAGTCGATGTCTATATCCGCTACCTGCGGCGCA
AGATAGACGATAATTTTGAACCCAAGTTACTCTATACCATTCGCGGCAGCGGCTATTGCCTCCGGGAACCTGGTAAAAGC
TAG

Upstream 100 bases:

>100_bases
GTGTTACCATAAATAATTAGATTTAGATTTAAGGGTCTCCCTGCCTCTAACCTGCTCCGGGAGTAGGTAAATCCAACCTG
AGGGGAGCGAAAGCCTGGTC

Downstream 100 bases:

>100_bases
GCCTAGAGGGGCATGGGAGGCTTTAACTTGCGGCAGAAATTTTCCACCTGGCTCCGCGGTATTCCCCTGCGGTGGCGGCT
GACGGCCTGGTATGTTTTCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MGRPAASLWVPGGDMRILVVEDETTLANTLARCLREEGYATDIAYDGEEGVAFAETVVYDLIILDLMLPRLDGMEVIRRL
RNERIETPVLMLTARDTVADKVRGLDAGADDYLTKPFALAELLARVRALLRRESDNKSTVLQVGDLVMDTVSRQVRRGDR
EINLTNKEYALLEYLMRNPNRVLTRTQIAEHVWDYDFSGMSNIVDVYIRYLRRKIDDNFEPKLLYTIRGSGYCLREPGKS

Sequences:

>Translated_240_residues
MGRPAASLWVPGGDMRILVVEDETTLANTLARCLREEGYATDIAYDGEEGVAFAETVVYDLIILDLMLPRLDGMEVIRRL
RNERIETPVLMLTARDTVADKVRGLDAGADDYLTKPFALAELLARVRALLRRESDNKSTVLQVGDLVMDTVSRQVRRGDR
EINLTNKEYALLEYLMRNPNRVLTRTQIAEHVWDYDFSGMSNIVDVYIRYLRRKIDDNFEPKLLYTIRGSGYCLREPGKS
>Mature_239_residues
GRPAASLWVPGGDMRILVVEDETTLANTLARCLREEGYATDIAYDGEEGVAFAETVVYDLIILDLMLPRLDGMEVIRRLR
NERIETPVLMLTARDTVADKVRGLDAGADDYLTKPFALAELLARVRALLRRESDNKSTVLQVGDLVMDTVSRQVRRGDRE
INLTNKEYALLEYLMRNPNRVLTRTQIAEHVWDYDFSGMSNIVDVYIRYLRRKIDDNFEPKLLYTIRGSGYCLREPGKS

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=48.6607142857143, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=47.2727272727273, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=40.990990990991, Blast_Score=166, Evalue=9e-43,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=42.7272727272727, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=38.1818181818182, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=36.8181818181818, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=39.2694063926941, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=37.5, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=34.3612334801762, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=33.7719298245614, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=33.9366515837104, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=32.5991189427313, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=31.6017316017316, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=28.448275862069, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788550, Length=144, Percent_Identity=29.8611111111111, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=33.6633663366337, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI48994928, Length=134, Percent_Identity=32.089552238806, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=127, Percent_Identity=30.7086614173228, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=34.2857142857143, Blast_Score=61, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=104, Percent_Identity=29.8076923076923, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27408; Mature: 27277

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRPAASLWVPGGDMRILVVEDETTLANTLARCLREEGYATDIAYDGEEGVAFAETVVYD
CCCCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCEECEEECCCCCHHHHHHHHHH
LIILDLMLPRLDGMEVIRRLRNERIETPVLMLTARDTVADKVRGLDAGADDYLTKPFALA
HHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCCCHHHHCCHHHHH
ELLARVRALLRRESDNKSTVLQVGDLVMDTVSRQVRRGDREINLTNKEYALLEYLMRNPN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCC
RVLTRTQIAEHVWDYDFSGMSNIVDVYIRYLRRKIDDNFEPKLLYTIRGSGYCLREPGKS
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCCCC
>Mature Secondary Structure 
GRPAASLWVPGGDMRILVVEDETTLANTLARCLREEGYATDIAYDGEEGVAFAETVVYD
CCCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCEECEEECCCCCHHHHHHHHHH
LIILDLMLPRLDGMEVIRRLRNERIETPVLMLTARDTVADKVRGLDAGADDYLTKPFALA
HHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCCCHHHHCCHHHHH
ELLARVRALLRRESDNKSTVLQVGDLVMDTVSRQVRRGDREINLTNKEYALLEYLMRNPN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCC
RVLTRTQIAEHVWDYDFSGMSNIVDVYIRYLRRKIDDNFEPKLLYTIRGSGYCLREPGKS
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]