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The map label for this gene is arlS [H]

Identifier: 83590321

GI number: 83590321

Start: 1524852

End: 1526231

Strand: Reverse

Name: arlS [H]

Synonym: Moth_1477

Alternate gene names: 83590321

Gene position: 1526231-1524852 (Counterclockwise)

Preceding gene: 83590322

Following gene: 83590320

Centisome position: 58.06

GC content: 59.71

Gene sequence:

>1380_bases
TTGCGGCAGAAATTTTCCACCTGGCTCCGCGGTATTCCCCTGCGGTGGCGGCTGACGGCCTGGTATGTTTTCTTGCTGGC
CTTGATCCTGGCCGGCTTCAGCGCTTTTATTTACTTTAACATGTCCCGGAGCCTGAAACAGGGCCTGGATTCTTTATTAT
TCTCCCAGGGGGAACAGGTTTTAAGCAGCCTGGACAACGAGAACGGCCTGCCACGCCTGGACCCCAATTTGCCCCTCCTG
CCCGGTACTTACTTTGGCCTTTACGACACCGGAGGTAAAGTCCTGGATACAAACATGCCGGCGGACCTGGCTACCGGCTT
CCAGGTGAAGGGCTTAACGGCCAGCCGGCCCGCAACAGTGGAGATTAAGGGGGCCGAATGGCGGGTGCTCCTGGTCCCGG
TAAGGGAAAAAGGCCAGCAACCTTACTGGGTCCTGGTTGTACGCTCGGTCGAAGAGACCGAAAAGCCCCTGGACCGCCTG
CTGTTATTTATCCTTATTGCCATCCCCATGACCCTGCTGGTGGCGGCGGGAGGGGGTATTTTCCTGGCCCGGCGGGCGTT
GCAGCCTATTGATAGAATTGCCGCCAAAGCCCGCCAGATCAGCGCTACTGACCTGAGCCGGCGCCTGGACCTGCCCCACG
GTAACGACGAGGTGGGGCACCTGGTGGCCACCCTGGACGAGATGCTGGATCGCCTGGACCGGGCCTTTCAGCGCCAGCGG
CAGTTTACTGCCGACGCCTCCCACGAATTTCGCACCCCCCTGGCCGTCATCCGCAGCCAGGCCGAAGCGGCCCTACAGCG
GCAGCACTCGCCGGCAGAGTACCGCCAGGCCCTGGAAATAATCCGTGATCAGGCGGAGTGGATGGGTAACCTGGTCGCCA
AGTTATTGCTTTTGGCCCGGAGCGACGACAGGATGGAACAGATGGAGATGGAACCCCTGGATTTGGGCGAACTGGTGGAA
GGCGTCACGGCCGAATTCCAGGGGATGGCGGCGGAAAAGGGCCTGAGGCTGGTAAAAAAAATTAAGGAAAAAGTGGTCGT
TCGCGGGGATCAGACACGCTTGACCCAGCTCCTGGCCAATCTGGTGGATAATGCCATCAAATATACGCCGGAAGGGGAGG
TGGTCGTCAGCCTGGAACGGCGCGGCCGGCAGGCCCTGCTGCAGGTGCAGGATACGGGAGTAGGTATCCCGGAGGAACAT
CTGGCCCATATCTTTGAGCGATTCTACCGGGTCGATAAAGCCCGTTCCCGGGCGGAAGGGGGCTTTGGCCTGGGACTGGC
TATCTGCGACTGGATCGTCCGCGCCCATAACGGCAAAATTGAGGTAGAAAGTGCGGTGGGGCGGGGAACAACCTTTAAAG
TATGGTTGCCGGTTGAATGA

Upstream 100 bases:

>100_bases
TAATTTTGAACCCAAGTTACTCTATACCATTCGCGGCAGCGGCTATTGCCTCCGGGAACCTGGTAAAAGCTAGGCCTAGA
GGGGCATGGGAGGCTTTAAC

Downstream 100 bases:

>100_bases
AGGGTTACATTAAAAAACTCTAATCTTCCATTAATAACCCTTTAATTCAAAGGTCTTATTCTATAATCGTCGGGTACCCG
ATAGATTAAATTTACGAAAG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRQKFSTWLRGIPLRWRLTAWYVFLLALILAGFSAFIYFNMSRSLKQGLDSLLFSQGEQVLSSLDNENGLPRLDPNLPLL
PGTYFGLYDTGGKVLDTNMPADLATGFQVKGLTASRPATVEIKGAEWRVLLVPVREKGQQPYWVLVVRSVEETEKPLDRL
LLFILIAIPMTLLVAAGGGIFLARRALQPIDRIAAKARQISATDLSRRLDLPHGNDEVGHLVATLDEMLDRLDRAFQRQR
QFTADASHEFRTPLAVIRSQAEAALQRQHSPAEYRQALEIIRDQAEWMGNLVAKLLLLARSDDRMEQMEMEPLDLGELVE
GVTAEFQGMAAEKGLRLVKKIKEKVVVRGDQTRLTQLLANLVDNAIKYTPEGEVVVSLERRGRQALLQVQDTGVGIPEEH
LAHIFERFYRVDKARSRAEGGFGLGLAICDWIVRAHNGKIEVESAVGRGTTFKVWLPVE

Sequences:

>Translated_459_residues
MRQKFSTWLRGIPLRWRLTAWYVFLLALILAGFSAFIYFNMSRSLKQGLDSLLFSQGEQVLSSLDNENGLPRLDPNLPLL
PGTYFGLYDTGGKVLDTNMPADLATGFQVKGLTASRPATVEIKGAEWRVLLVPVREKGQQPYWVLVVRSVEETEKPLDRL
LLFILIAIPMTLLVAAGGGIFLARRALQPIDRIAAKARQISATDLSRRLDLPHGNDEVGHLVATLDEMLDRLDRAFQRQR
QFTADASHEFRTPLAVIRSQAEAALQRQHSPAEYRQALEIIRDQAEWMGNLVAKLLLLARSDDRMEQMEMEPLDLGELVE
GVTAEFQGMAAEKGLRLVKKIKEKVVVRGDQTRLTQLLANLVDNAIKYTPEGEVVVSLERRGRQALLQVQDTGVGIPEEH
LAHIFERFYRVDKARSRAEGGFGLGLAICDWIVRAHNGKIEVESAVGRGTTFKVWLPVE
>Mature_459_residues
MRQKFSTWLRGIPLRWRLTAWYVFLLALILAGFSAFIYFNMSRSLKQGLDSLLFSQGEQVLSSLDNENGLPRLDPNLPLL
PGTYFGLYDTGGKVLDTNMPADLATGFQVKGLTASRPATVEIKGAEWRVLLVPVREKGQQPYWVLVVRSVEETEKPLDRL
LLFILIAIPMTLLVAAGGGIFLARRALQPIDRIAAKARQISATDLSRRLDLPHGNDEVGHLVATLDEMLDRLDRAFQRQR
QFTADASHEFRTPLAVIRSQAEAALQRQHSPAEYRQALEIIRDQAEWMGNLVAKLLLLARSDDRMEQMEMEPLDLGELVE
GVTAEFQGMAAEKGLRLVKKIKEKVVVRGDQTRLTQLLANLVDNAIKYTPEGEVVVSLERRGRQALLQVQDTGVGIPEEH
LAHIFERFYRVDKARSRAEGGFGLGLAICDWIVRAHNGKIEVESAVGRGTTFKVWLPVE

Specific function: Member of the two-component regulatory system ArlS/ArlR. ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=340, Percent_Identity=30.8823529411765, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=34.7670250896057, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=37.2727272727273, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=31.7991631799163, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=32.7659574468085, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=31.4410480349345, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787894, Length=301, Percent_Identity=29.5681063122924, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790346, Length=292, Percent_Identity=29.4520547945205, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1789403, Length=292, Percent_Identity=29.7945205479452, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=26.8, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=25.5102040816327, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790861, Length=275, Percent_Identity=32.3636363636364, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=29.8642533936652, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790551, Length=228, Percent_Identity=31.140350877193, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081816, Length=230, Percent_Identity=29.5652173913043, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789808, Length=287, Percent_Identity=28.2229965156794, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787374, Length=283, Percent_Identity=27.208480565371, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=33.1858407079646, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=28.3950617283951, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=24.7747747747748, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51509; Mature: 51509

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQKFSTWLRGIPLRWRLTAWYVFLLALILAGFSAFIYFNMSRSLKQGLDSLLFSQGEQV
CCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LSSLDNENGLPRLDPNLPLLPGTYFGLYDTGGKVLDTNMPADLATGFQVKGLTASRPATV
HHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHCCCEEECCCCCCCCEE
EIKGAEWRVLLVPVREKGQQPYWVLVVRSVEETEKPLDRLLLFILIAIPMTLLVAAGGGI
EEECCCEEEEEEEHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FLARRALQPIDRIAAKARQISATDLSRRLDLPHGNDEVGHLVATLDEMLDRLDRAFQRQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QFTADASHEFRTPLAVIRSQAEAALQRQHSPAEYRQALEIIRDQAEWMGNLVAKLLLLAR
HHCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDDRMEQMEMEPLDLGELVEGVTAEFQGMAAEKGLRLVKKIKEKVVVRGDQTRLTQLLAN
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LVDNAIKYTPEGEVVVSLERRGRQALLQVQDTGVGIPEEHLAHIFERFYRVDKARSRAEG
HHHHHHEECCCCCEEEEHHHCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GFGLGLAICDWIVRAHNGKIEVESAVGRGTTFKVWLPVE
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure
MRQKFSTWLRGIPLRWRLTAWYVFLLALILAGFSAFIYFNMSRSLKQGLDSLLFSQGEQV
CCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LSSLDNENGLPRLDPNLPLLPGTYFGLYDTGGKVLDTNMPADLATGFQVKGLTASRPATV
HHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHCCCEEECCCCCCCCEE
EIKGAEWRVLLVPVREKGQQPYWVLVVRSVEETEKPLDRLLLFILIAIPMTLLVAAGGGI
EEECCCEEEEEEEHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FLARRALQPIDRIAAKARQISATDLSRRLDLPHGNDEVGHLVATLDEMLDRLDRAFQRQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QFTADASHEFRTPLAVIRSQAEAALQRQHSPAEYRQALEIIRDQAEWMGNLVAKLLLLAR
HHCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDDRMEQMEMEPLDLGELVEGVTAEFQGMAAEKGLRLVKKIKEKVVVRGDQTRLTQLLAN
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LVDNAIKYTPEGEVVVSLERRGRQALLQVQDTGVGIPEEHLAHIFERFYRVDKARSRAEG
HHHHHHEECCCCCEEEEHHHCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GFGLGLAICDWIVRAHNGKIEVESAVGRGTTFKVWLPVE
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA