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The map label for this gene is rsbRA [H]

Identifier: 83590319

GI number: 83590319

Start: 1523147

End: 1523965

Strand: Reverse

Name: rsbRA [H]

Synonym: Moth_1475

Alternate gene names: 83590319

Gene position: 1523965-1523147 (Counterclockwise)

Preceding gene: 83590320

Following gene: 83590318

Centisome position: 57.97

GC content: 45.42

Gene sequence:

>819_bases
GTGGATATATGTGGAGAACTAAAAGCAGAGAACATTGTCGAAAAGGCTATAAATTTGTTGAGTAAAGAAGACCAGGCGGG
GGTCCATTTTAATGAAATATCAGCTTTAACCCGTGATTTTTGCCGCGCCATCTTGAGCGATCTCGAACAATCTGGCTTTA
CTACTTCAGAACTCGAAAAGGAAATAGCAGATAAAGTAAAAATAATGTTTGCCCAGGGATATCATATCGAGGTTCTTCAA
CTTATATTAGAAAAGATTTTAGACAGCTTTATAAGCGTTATCCGGGAGCAGTATCATGACCTGCAAGCAGCAGCATCTTA
CATTACCACAGTCAGGGACCATATTTTTAAAGGCACATCTTTTTTACTAAAAATGGCTTTGCAGACCCAGCGCGAGGTAA
TCCAGAAGCAAAACGAGGCCTTAATGGAGCTATCGACACCGGTAATACCCCTTATGCAGGATATTCTTTTATTGCCGTTA
ATCGGTACTATCGATACCAGGCGGGCTAAAGAAATAATGGATAATCTCCTGGAAGGTATAGTGCGCTACCAGGCCGAGGT
TGTCATCATTGATATCAGCGGCGTGCCGGTAGTAGACACCCAGGTTGCCCATCACTTGATTAAAACTGTCAAAGCCGCCA
GGCTTTTAGGAAGCCGTTGCATTCTGGTGGGTATCAGGCCGGAGCTGGCCCAAACAATTGTCCGTCTGGGGATCGATTTT
CCGGATATTATTACCAAAAATAACCTCCACGCCGGGCTGGAACTGGCCTTTCGCTGGCTGGGCTACAGGCTGGAGCGGGT
GGAGCACGACCATGAGTAG

Upstream 100 bases:

>100_bases
TTGGACGCGGGGATACCAGGTAAAATTTTCTTGACGGTAAAAAAGGCTCCCCCTATAATTAGGGTTATAGAATAATGTCA
AATTAAGGAGGAAAGCGTCG

Downstream 100 bases:

>100_bases
CCGGGTGCCCATCCTGAAAGTGGACGATTACTGGGTAGTGGCCATTGAAGAAACCCTGCACGATCAAAGCGTTATCCAGT
TTAAAGAGGAATTATTACAT

Product: anti-sigma-factor antagonist domain-containing protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MDICGELKAENIVEKAINLLSKEDQAGVHFNEISALTRDFCRAILSDLEQSGFTTSELEKEIADKVKIMFAQGYHIEVLQ
LILEKILDSFISVIREQYHDLQAAASYITTVRDHIFKGTSFLLKMALQTQREVIQKQNEALMELSTPVIPLMQDILLLPL
IGTIDTRRAKEIMDNLLEGIVRYQAEVVIIDISGVPVVDTQVAHHLIKTVKAARLLGSRCILVGIRPELAQTIVRLGIDF
PDIITKNNLHAGLELAFRWLGYRLERVEHDHE

Sequences:

>Translated_272_residues
MDICGELKAENIVEKAINLLSKEDQAGVHFNEISALTRDFCRAILSDLEQSGFTTSELEKEIADKVKIMFAQGYHIEVLQ
LILEKILDSFISVIREQYHDLQAAASYITTVRDHIFKGTSFLLKMALQTQREVIQKQNEALMELSTPVIPLMQDILLLPL
IGTIDTRRAKEIMDNLLEGIVRYQAEVVIIDISGVPVVDTQVAHHLIKTVKAARLLGSRCILVGIRPELAQTIVRLGIDF
PDIITKNNLHAGLELAFRWLGYRLERVEHDHE
>Mature_272_residues
MDICGELKAENIVEKAINLLSKEDQAGVHFNEISALTRDFCRAILSDLEQSGFTTSELEKEIADKVKIMFAQGYHIEVLQ
LILEKILDSFISVIREQYHDLQAAASYITTVRDHIFKGTSFLLKMALQTQREVIQKQNEALMELSTPVIPLMQDILLLPL
IGTIDTRRAKEIMDNLLEGIVRYQAEVVIIDISGVPVVDTQVAHHLIKTVKAARLLGSRCILVGIRPELAQTIVRLGIDF
PDIITKNNLHAGLELAFRWLGYRLERVEHDHE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 30775; Mature: 30775

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50801 STAS ; PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDICGELKAENIVEKAINLLSKEDQAGVHFNEISALTRDFCRAILSDLEQSGFTTSELEK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EIADKVKIMFAQGYHIEVLQLILEKILDSFISVIREQYHDLQAAASYITTVRDHIFKGTS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLKMALQTQREVIQKQNEALMELSTPVIPLMQDILLLPLIGTIDTRRAKEIMDNLLEGI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VRYQAEVVIIDISGVPVVDTQVAHHLIKTVKAARLLGSRCILVGIRPELAQTIVRLGIDF
HHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCC
PDIITKNNLHAGLELAFRWLGYRLERVEHDHE
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDICGELKAENIVEKAINLLSKEDQAGVHFNEISALTRDFCRAILSDLEQSGFTTSELEK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EIADKVKIMFAQGYHIEVLQLILEKILDSFISVIREQYHDLQAAASYITTVRDHIFKGTS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLKMALQTQREVIQKQNEALMELSTPVIPLMQDILLLPLIGTIDTRRAKEIMDNLLEGI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VRYQAEVVIIDISGVPVVDTQVAHHLIKTVKAARLLGSRCILVGIRPELAQTIVRLGIDF
HHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCC
PDIITKNNLHAGLELAFRWLGYRLERVEHDHE
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]