Click here to switch to the map view.

The map label for this gene is fieF [H]

Identifier: 83593960

GI number: 83593960

Start: 3057457

End: 3058434

Strand: Direct

Name: fieF [H]

Synonym: Rru_A2628

Alternate gene names: 83593960

Gene position: 3057457-3058434 (Clockwise)

Preceding gene: 83593959

Following gene: 83593962

Centisome position: 70.24

GC content: 65.95

Gene sequence:

>978_bases
ATGGGGACGCAACGATCCGACACCCGCGACCAATCGGCGCGGCTGATGCGCCGGGCCACCTACGCCTCGGTCACCGTGGC
CATGACCCTGGTCGTCGCCAAGCTGGTGGCCTGGGTGCTGACGGATTCGGTCGCCCTGCTCTCGACCCTGATCGACAGCC
TGATCGATGTCGGGGCCTCGCTGGTCACCTTGCTGGCCGTGCGCGAGGCCCTGACCCCGGCCGACGAGGAGCACCGCTTT
GGCCATGGCAAGGCCGAACCCTTGGCCGGCCTCGGGCAGGCGGCCTTCATCGCCGGCTCGGGCATTTTCCTGGTGATCGA
GGCGGCCGGGCGCCTGACCGCTCCGCTGCCGGTGCAGCGCGGCGAAATCGGCATCGCGGTGATGGTGTTTTCCATCCTGG
CCACCATCGGGCTGGTCGCCTATCAGCGGCGGGTGATCGCCCAGACCAAATCGGTGGCGATCAGCGCCGATAGCCTGCAT
TACGCCGGCGATCTGCTGATCAACCTGTCGGTAATCGTCTCGCTGGGATTGGCGATGACCGTCGACCTGCCGATCCTCGA
TCCGCTGTTCGCCATCGCCATCGCCCTTTGGCTGATGAAGAACGCCTGGACCATCGGCGCCAACAGCGTGAACCTGCTGA
TGGACCGCGAACTGCCGCCCGAGGACCGGGTCCGCATCATCAAGCTCGCCCTGGAAAACCCCCGGGTCTTCGATATCCAC
GATCTGCGCACCCGCTCTTCGGGGCCGCAAACCTTCATCCAGCTCAATGTCGAACTTGATGGCGAGATGACGCTGTCGGC
CTCCCACGCCATCGTCACCGAGATCGAGAACCGCCTGCGCGCCGCCTTCCCCGGGGCCGAGGTGCTAATCCACCAGGACC
CGGCCGGCATTCAGGAAGACCACCACCCCGATTTTGCCTATGAAGACACCTCGGCCCTGCTTGAAGCCGATGCCGCCAGC
CAGCCGCGCCGCTTATAG

Upstream 100 bases:

>100_bases
TGTATCGTAGCGAGGGAAGCGGCTGGACCCACAGCCGGCTTTATCCCTAAGGAACCTCGTATTCCCCAAAAGGTCGGGGT
GCGACGGGAAAGGAAAACCC

Downstream 100 bases:

>100_bases
CGGTATCCTGATCAAGCGATCGCCGTGAAGCGGACGACGCCATCGACCTCGCTGCGCCGCAAGCGTCCCTGACCTTCCAA
CCAATGGGCATGGGCCAGGG

Product: cation efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MGTQRSDTRDQSARLMRRATYASVTVAMTLVVAKLVAWVLTDSVALLSTLIDSLIDVGASLVTLLAVREALTPADEEHRF
GHGKAEPLAGLGQAAFIAGSGIFLVIEAAGRLTAPLPVQRGEIGIAVMVFSILATIGLVAYQRRVIAQTKSVAISADSLH
YAGDLLINLSVIVSLGLAMTVDLPILDPLFAIAIALWLMKNAWTIGANSVNLLMDRELPPEDRVRIIKLALENPRVFDIH
DLRTRSSGPQTFIQLNVELDGEMTLSASHAIVTEIENRLRAAFPGAEVLIHQDPAGIQEDHHPDFAYEDTSALLEADAAS
QPRRL

Sequences:

>Translated_325_residues
MGTQRSDTRDQSARLMRRATYASVTVAMTLVVAKLVAWVLTDSVALLSTLIDSLIDVGASLVTLLAVREALTPADEEHRF
GHGKAEPLAGLGQAAFIAGSGIFLVIEAAGRLTAPLPVQRGEIGIAVMVFSILATIGLVAYQRRVIAQTKSVAISADSLH
YAGDLLINLSVIVSLGLAMTVDLPILDPLFAIAIALWLMKNAWTIGANSVNLLMDRELPPEDRVRIIKLALENPRVFDIH
DLRTRSSGPQTFIQLNVELDGEMTLSASHAIVTEIENRLRAAFPGAEVLIHQDPAGIQEDHHPDFAYEDTSALLEADAAS
QPRRL
>Mature_324_residues
GTQRSDTRDQSARLMRRATYASVTVAMTLVVAKLVAWVLTDSVALLSTLIDSLIDVGASLVTLLAVREALTPADEEHRFG
HGKAEPLAGLGQAAFIAGSGIFLVIEAAGRLTAPLPVQRGEIGIAVMVFSILATIGLVAYQRRVIAQTKSVAISADSLHY
AGDLLINLSVIVSLGLAMTVDLPILDPLFAIAIALWLMKNAWTIGANSVNLLMDRELPPEDRVRIIKLALENPRVFDIHD
LRTRSSGPQTFIQLNVELDGEMTLSASHAIVTEIENRLRAAFPGAEVLIHQDPAGIQEDHHPDFAYEDTSALLEADAASQ
PRRL

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=285, Percent_Identity=41.4035087719298, Blast_Score=230, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI72000060, Length=322, Percent_Identity=21.7391304347826, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI72000062, Length=322, Percent_Identity=21.7391304347826, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 35033; Mature: 34902

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTQRSDTRDQSARLMRRATYASVTVAMTLVVAKLVAWVLTDSVALLSTLIDSLIDVGAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVTLLAVREALTPADEEHRFGHGKAEPLAGLGQAAFIAGSGIFLVIEAAGRLTAPLPVQR
HHHHHHHHHHCCCCCHHHCCCCCCCCCHHCCCCHHEEECCCEEEEEEECCCCCCCCCCCC
GEIGIAVMVFSILATIGLVAYQRRVIAQTKSVAISADSLHYAGDLLINLSVIVSLGLAMT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHE
VDLPILDPLFAIAIALWLMKNAWTIGANSVNLLMDRELPPEDRVRIIKLALENPRVFDIH
ECCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCCHHHEEEEEEEECCCCEEEEH
DLRTRSSGPQTFIQLNVELDGEMTLSASHAIVTEIENRLRAAFPGAEVLIHQDPAGIQED
HHHCCCCCCCEEEEEEEEECCCEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
HHPDFAYEDTSALLEADAASQPRRL
CCCCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GTQRSDTRDQSARLMRRATYASVTVAMTLVVAKLVAWVLTDSVALLSTLIDSLIDVGAS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVTLLAVREALTPADEEHRFGHGKAEPLAGLGQAAFIAGSGIFLVIEAAGRLTAPLPVQR
HHHHHHHHHHCCCCCHHHCCCCCCCCCHHCCCCHHEEECCCEEEEEEECCCCCCCCCCCC
GEIGIAVMVFSILATIGLVAYQRRVIAQTKSVAISADSLHYAGDLLINLSVIVSLGLAMT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHE
VDLPILDPLFAIAIALWLMKNAWTIGANSVNLLMDRELPPEDRVRIIKLALENPRVFDIH
ECCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCCHHHEEEEEEEECCCCEEEEH
DLRTRSSGPQTFIQLNVELDGEMTLSASHAIVTEIENRLRAAFPGAEVLIHQDPAGIQED
HHHCCCCCCCEEEEEEEEECCCEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
HHPDFAYEDTSALLEADAASQPRRL
CCCCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA