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The map label for this gene is proX [H]

Identifier: 83593812

GI number: 83593812

Start: 2877507

End: 2878538

Strand: Direct

Name: proX [H]

Synonym: Rru_A2477

Alternate gene names: 83593812

Gene position: 2877507-2878538 (Clockwise)

Preceding gene: 83593811

Following gene: 83593816

Centisome position: 66.11

GC content: 64.83

Gene sequence:

>1032_bases
ATGATCTTGCCCGCCGCGCCGCGCCTCCGCTTTCTCGCCCCCGTGTCGGCCCCCGTTCTGGCGGTTGTCTGCGCCCTTGG
CGTCTTGCCGGCAAACGCCGCCGAGCAGCCGGGCAAAGGCGTCTCCGTCCTGCCGATCAAATCCTCGATCGCCGAAGAGA
CCTTCCAGACGCTGCTGGTCTCGCGCGCCCTGGCAGAGCTGGGCTATGACGTGAAGGACATCGGCGAGATCGATTACGCC
GCCGGTCACGTGGCCTTGGCCAATGGCGACGCCACCTTCCTGGCCGCCCATTGGAATCCGCTTCATAAGGATTTCTATGA
GCGCGCCGGCGGCGACGCCAAGCTCTATCGCGACGGGGTTTATTCCGAAGGCGCCTTGCAGGGCTATCTGATCGACAAGA
AGACGGCCGAGGCCCACGCCATCACCCGCATCGACCAACTGAAAGACCCGAAGATCGCCGCCCTCTTCGACCATGACGGC
GACGGCAAGGCCGATCTCGCCGGCTGCACCCCTGGCTGGGGCTGCGAGGCGGTCATCGAGCACCATCTCGACGCCTATGG
CCTGCGCAAAACCGTCACCCATCAGCAAGGGTCCTATTCGGCGCTGATGGCCGATACGATCACCCGCTTCAAGAAGGGCG
CCTCGGTGCTCTATTACACCTGGACCCCCTATTGGGTTTCCGGGGTTCTGGTTCCCGGGCGCGATGTCACGTGGCTGCAA
GTGCCGTTCTCAGCCCTGCCCGGCAGCCGCAAGGATGTTGATACGGCGCTGGCCACCGGTCAGAACTACGGCTTCCAGGC
GAACACTCAGCAAATCGTCGCCAATCGCGCCTGGGCCGAGGCCAATCCGGCCGCCGCCACGCTGTTTTCCCTGATGCGTC
TGCCCAACGCCGATATCAACGCCCAGAACCTGCGCATGCGCAACGGCGAGAACAGCCAAGCCGATATCGCCCGCCATGTC
GACGGCTGGATCGCCGGCCATCGCCAGACCTGGGACGGTTGGCTGGCCCAAGCCCGCAAGGCCGCGCATTAA

Upstream 100 bases:

>100_bases
ACACCAGCGGTCCCGTCGGACTGGTCGTGCGTCTGGTGTCCCTGCGCAAGGGCACCGCCCACCCCGCTCGCGAAAGCCTG
CCAAAAGGAGAACCGATCTC

Downstream 100 bases:

>100_bases
GCCCAGGCCAGCCCTTTAGATACGGTGCGCGGGACCCATGGTCCCCGCGTACCGCTCTAAGAGCTTGATCGTGAAGCAAA
TCGTCGCCGCACTCTGGACC

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MILPAAPRLRFLAPVSAPVLAVVCALGVLPANAAEQPGKGVSVLPIKSSIAEETFQTLLVSRALAELGYDVKDIGEIDYA
AGHVALANGDATFLAAHWNPLHKDFYERAGGDAKLYRDGVYSEGALQGYLIDKKTAEAHAITRIDQLKDPKIAALFDHDG
DGKADLAGCTPGWGCEAVIEHHLDAYGLRKTVTHQQGSYSALMADTITRFKKGASVLYYTWTPYWVSGVLVPGRDVTWLQ
VPFSALPGSRKDVDTALATGQNYGFQANTQQIVANRAWAEANPAAATLFSLMRLPNADINAQNLRMRNGENSQADIARHV
DGWIAGHRQTWDGWLAQARKAAH

Sequences:

>Translated_343_residues
MILPAAPRLRFLAPVSAPVLAVVCALGVLPANAAEQPGKGVSVLPIKSSIAEETFQTLLVSRALAELGYDVKDIGEIDYA
AGHVALANGDATFLAAHWNPLHKDFYERAGGDAKLYRDGVYSEGALQGYLIDKKTAEAHAITRIDQLKDPKIAALFDHDG
DGKADLAGCTPGWGCEAVIEHHLDAYGLRKTVTHQQGSYSALMADTITRFKKGASVLYYTWTPYWVSGVLVPGRDVTWLQ
VPFSALPGSRKDVDTALATGQNYGFQANTQQIVANRAWAEANPAAATLFSLMRLPNADINAQNLRMRNGENSQADIARHV
DGWIAGHRQTWDGWLAQARKAAH
>Mature_343_residues
MILPAAPRLRFLAPVSAPVLAVVCALGVLPANAAEQPGKGVSVLPIKSSIAEETFQTLLVSRALAELGYDVKDIGEIDYA
AGHVALANGDATFLAAHWNPLHKDFYERAGGDAKLYRDGVYSEGALQGYLIDKKTAEAHAITRIDQLKDPKIAALFDHDG
DGKADLAGCTPGWGCEAVIEHHLDAYGLRKTVTHQQGSYSALMADTITRFKKGASVLYYTWTPYWVSGVLVPGRDVTWLQ
VPFSALPGSRKDVDTALATGQNYGFQANTQQIVANRAWAEANPAAATLFSLMRLPNADINAQNLRMRNGENSQADIARHV
DGWIAGHRQTWDGWLAQARKAAH

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=309, Percent_Identity=63.7540453074434, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 37083; Mature: 37083

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPAAPRLRFLAPVSAPVLAVVCALGVLPANAAEQPGKGVSVLPIKSSIAEETFQTLLV
CCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHH
SRALAELGYDVKDIGEIDYAAGHVALANGDATFLAAHWNPLHKDFYERAGGDAKLYRDGV
HHHHHHHCCCHHHHCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHCCCCCEEHHCCC
YSEGALQGYLIDKKTAEAHAITRIDQLKDPKIAALFDHDGDGKADLAGCTPGWGCEAVIE
CCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHH
HHLDAYGLRKTVTHQQGSYSALMADTITRFKKGASVLYYTWTPYWVSGVLVPGRDVTWLQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHEEEEECCCCEEEEE
VPFSALPGSRKDVDTALATGQNYGFQANTQQIVANRAWAEANPAAATLFSLMRLPNADIN
CCHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
AQNLRMRNGENSQADIARHVDGWIAGHRQTWDGWLAQARKAAH
HHHEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MILPAAPRLRFLAPVSAPVLAVVCALGVLPANAAEQPGKGVSVLPIKSSIAEETFQTLLV
CCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHH
SRALAELGYDVKDIGEIDYAAGHVALANGDATFLAAHWNPLHKDFYERAGGDAKLYRDGV
HHHHHHHCCCHHHHCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHCCCCCEEHHCCC
YSEGALQGYLIDKKTAEAHAITRIDQLKDPKIAALFDHDGDGKADLAGCTPGWGCEAVIE
CCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHH
HHLDAYGLRKTVTHQQGSYSALMADTITRFKKGASVLYYTWTPYWVSGVLVPGRDVTWLQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHEEEEECCCCEEEEE
VPFSALPGSRKDVDTALATGQNYGFQANTQQIVANRAWAEANPAAATLFSLMRLPNADIN
CCHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
AQNLRMRNGENSQADIARHVDGWIAGHRQTWDGWLAQARKAAH
HHHEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]