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The map label for this gene is ubiE

Identifier: 82751068

GI number: 82751068

Start: 1461762

End: 1462487

Strand: Reverse

Name: ubiE

Synonym: SAB1333c

Alternate gene names: 82751068

Gene position: 1462487-1461762 (Counterclockwise)

Preceding gene: 82751069

Following gene: 82751067

Centisome position: 53.33

GC content: 34.3

Gene sequence:

>726_bases
ATGGCTGACAATAAAGCAAATAAAGAGCAAGTACATCGCGTTTTTCAAAATATTTCAAAAAAATATGACAGATTAAATAA
TATTATTAGTTTTGAGCAGCATAAAGTATGGAGAAAACGTGTCATGAAAGACATGGGTGTTAGAAAAGGTACGAAAGCAT
TAGATGTTTGTTGTGGTACTGGTGATTGGACAATCGCATTAAGCAAAGCTGTAGGACCAACAGGAGAAGTTACTGGTATT
GACTTTAGTGAGAATATGTTAGAAGTAGGAAAAGAAAAAACTGCTTCAATGGAAAATGTTAAACTTGTTCATGGTGATGC
AATGGAATTGCCGTTTGGAGACAATTCTTTTGATTATGTAACAATTGGGTTTGGATTAAGGAATGTTCCAGACTATTTAG
TCGCGTTAAAAGAAATGAATAGAGTACTTAAACCAGGTGGTATGGTGGTATGTCTTGAAACGAGCCAACCAACTTTGCCA
GCCTTTAAACAAATGTATGCATTATACTTTAAATTTGTTATGCCTATTTTTGGAAAATTATTTGCAAAATCAAAAGAAGA
ATATGAATGGTTACAGCAATCTACGTTTAATTTTCCTGGAAAAGAAGAGTTGAAGCGCATGTTTGAAGAAGCGGGTTTCA
TAAATGTAAGAGTACGTAGTTTTACAGGGGGCGTTGCTGCAATGCACCTTGGCTATAAAGAAAAAGATAATACCAAAGGT
GATTAA

Upstream 100 bases:

>100_bases
ATTACTATCCATCATACTTCAAGAAATATAATCAAAGTGAAGTAAAGCATTACTTACACGATATCCAAAAAAGTTATTTA
AAAAGTAGAGGTAATTAAGC

Downstream 100 bases:

>100_bases
CGTGGCAAAGTTAAACATGAACAATGAAATTAAGAAAGTGGAACAACGACTTGAAAAGGCGATAAAAAGTAAAGATTCTG
TATTAGAACAGGCATCATTA

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGI
DFSENMLEVGKEKTASMENVKLVHGDAMELPFGDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLP
AFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKG
D

Sequences:

>Translated_241_residues
MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGI
DFSENMLEVGKEKTASMENVKLVHGDAMELPFGDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLP
AFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKG
D
>Mature_240_residues
ADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGID
FSENMLEVGKEKTASMENVKLVHGDAMELPFGDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLPA
FKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKGD

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI116063536, Length=260, Percent_Identity=35.7692307692308, Blast_Score=159, Evalue=1e-39,
Organism=Escherichia coli, GI48994983, Length=228, Percent_Identity=41.6666666666667, Blast_Score=187, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17557039, Length=238, Percent_Identity=35.2941176470588, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323526, Length=251, Percent_Identity=30.6772908366534, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24641702, Length=246, Percent_Identity=35.7723577235772, Blast_Score=144, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 27323; Mature: 27192

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS01183 UBIE_1 ; PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECC
GDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKLVHGDAMELPFGDNSFDYV
CCEEEEEECCCCCCCCEECCCCHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCCEE
TIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLPAFKQMYALYFKFVMPIFGKL
EECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
FAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKG
HHCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCCCCCCC
D
C
>Mature Secondary Structure 
ADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECC
GDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKLVHGDAMELPFGDNSFDYV
CCEEEEEECCCCCCCCEECCCCHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCCEE
TIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLPAFKQMYALYFKFVMPIFGKL
EECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
FAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKG
HHCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA