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The map label for this gene is hepT [H]

Identifier: 82751067

GI number: 82751067

Start: 1460801

End: 1461760

Strand: Reverse

Name: hepT [H]

Synonym: SAB1332c

Alternate gene names: 82751067

Gene position: 1461760-1460801 (Counterclockwise)

Preceding gene: 82751068

Following gene: 82751066

Centisome position: 53.3

GC content: 35.0

Gene sequence:

>960_bases
GTGGCAAAGTTAAACATGAACAATGAAATTAAGAAAGTGGAACAACGACTTGAAAAGGCGATAAAAAGTAAAGATTCTGT
ATTAGAACAGGCATCATTACACTTATTGTCTTCTGGTGGTAAAAGAGTACGCCCAGCATTTGTAATTCTGAGTAGCCAAT
TTGGCAAAGATGAACAAACGTCTGAACAAACGTATCAAGTTGCAGTCGCATTAGAGTTAATTCATATGGCAACACTTGTT
CATGATGACGTTATTGATAAAAGTGACAAGCGTCGAGGCAAGTTAACCATATCGAAGAAATGGGATCAGACAACTGCTAT
TTTAACTGGGAATTTTTTATTGGCATTAGGACTTGAACACTTAATGGCCGTTAAAGATAATCGTGTACATCAATTAATAT
CTGAATCTATCGTTGATGTTTGTAGAGGGGAACTTTTCCAATTTCAAGACCAATTTAACAGTCAACAGACAATTATCAAT
TATTTACGACGTATCAATCGCAAAACAGCACTGTTAATTCAGTTATCAACTGAAGTTGGTGCAATTACATCTCAATCTGA
TAAAGAGACTGTACGAAAATTGAAAATGATTGGTCATTATATAGGTATGAGCTTCCAAATCATTGATGATGTATTAGACT
TCACAAGTACCGAAAAGAAATTAGGTAAGCCGGTCGGAAGTGATTTGCTTAATGGTCATATTACGTTACCGATTTTATTA
GAAATGCGTAAAAACCCAGACTTCAAATTGAAAATCGAACAATTACGTCGTGATAGTGAACGCAAAGAATTTGACGAATG
TATCCAAATCATTAGAAAATCTGACAGCATCGATGAGGCTAAGTCAGTAAGTTCGAAGTATTTAAGTAAAGCTTTGGATT
TGATTTCTGAGTTACCAGATGGACATCCGAAATCACTACTTTTAAGTTTGACGAAAAAAATGGGCTCAAGAAACACATAG

Upstream 100 bases:

>100_bases
GAAGCGGGTTTCATAAATGTAAGAGTACGTAGTTTTACAGGGGGCGTTGCTGCAATGCACCTTGGCTATAAAGAAAAAGA
TAATACCAAAGGTGATTAAC

Downstream 100 bases:

>100_bases
TATTTATGAAAAGTATTGAAAGCGCTTTACCAACCTGTTAATATATAATAGTAATATACATAAACCTATTAAACACAGGG
GGATACATAAAGTGGAACGT

Product: heptaprenyl diphosphate syntase component II

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLV
HDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIIN
YLRRINRKTALLIQLSTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILL
EMRKNPDFKLKIEQLRRDSERKEFDECIQIIRKSDSIDEAKSVSSKYLSKALDLISELPDGHPKSLLLSLTKKMGSRNT

Sequences:

>Translated_319_residues
MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLV
HDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIIN
YLRRINRKTALLIQLSTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILL
EMRKNPDFKLKIEQLRRDSERKEFDECIQIIRKSDSIDEAKSVSSKYLSKALDLISELPDGHPKSLLLSLTKKMGSRNT
>Mature_318_residues
AKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLVH
DDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINY
LRRINRKTALLIQLSTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILLE
MRKNPDFKLKIEQLRRDSERKEFDECIQIIRKSDSIDEAKSVSSKYLSKALDLISELPDGHPKSLLLSLTKKMGSRNT

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=315, Percent_Identity=30.4761904761905, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1789578, Length=308, Percent_Identity=28.8961038961039, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1786623, Length=223, Percent_Identity=32.7354260089686, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17505681, Length=244, Percent_Identity=28.6885245901639, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319475, Length=309, Percent_Identity=29.126213592233, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24651612, Length=277, Percent_Identity=28.5198555956679, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281365769, Length=267, Percent_Identity=24.7191011235955, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24660002, Length=267, Percent_Identity=24.7191011235955, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36146; Mature: 36015

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCCCCCH
SEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHH
LMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINYLRRINRKTALLIQLSTEVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCHHC
AITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCCCHHHHCCCCHHHHHE
EMRKNPDFKLKIEQLRRDSERKEFDECIQIIRKSDSIDEAKSVSSKYLSKALDLISELPD
EECCCCCCEEEHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GHPKSLLLSLTKKMGSRNT
CCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCCCCCH
SEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHH
LMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINYLRRINRKTALLIQLSTEVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCHHC
AITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCCCHHHHCCCCHHHHHE
EMRKNPDFKLKIEQLRRDSERKEFDECIQIIRKSDSIDEAKSVSSKYLSKALDLISELPD
EECCCCCCEEEHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GHPKSLLLSLTKKMGSRNT
CCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]