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The map label for this gene is ald

Identifier: 82751039

GI number: 82751039

Start: 1427437

End: 1428555

Strand: Reverse

Name: ald

Synonym: SAB1304c

Alternate gene names: 82751039

Gene position: 1428555-1427437 (Counterclockwise)

Preceding gene: 82751040

Following gene: 82751038

Centisome position: 52.09

GC content: 35.48

Gene sequence:

>1119_bases
ATGTTAGTTGCAGTAGTCAAAGAATTAAAACAAGGTGAAGGACGTGTAGCTTGCACACCCGAAAATGTGCGTAAGTTAAC
GGCTGCAGGACATAAAGTAATTGTAGAAAAAAATGCTGGCATTGGTTCAGGATTTTCTAACGATATGTATGAAAAAGAAG
GCGCTAAGATCGTAACTCACGAACAAGCATGGGAAGCAGATCTTGTTATCAAAGTAAAAGAACCTCATGAAAGCGAATAT
CAATATTTCAAAAAGAATCAAATCATCTGGGGATTTTTACATCTAGCATCTTCAAAAGAAATAGTAGAAAAAATGCAAGG
AGTTGGTGTAATTGCGATTAGTGGTGAAACCATTATAAAAAATGGAAAAGCAGAATTATTAGCGCCAATGAGTGCTATAG
CAGGTCAACGCTCAGCAATTATGGGAGCTTACTACTCTGAAGCACAACATGGTGGTCAAGGTACTTTAGTGACTGGTGTA
CATGAAAATGTGGATATACCTGGTAGTACATATGTGATTTTCGGTGGTGGAGTAGCAGCAACAAATGCAGCAAATGTTGC
CTTGGGACTAAATGCTAAAGTAATCATTATCGAGTTAAACGATGACCGCATTAAATATCTTGAAGATATGTATGCAGAAA
AAGATGTCACAGTAGTCAAATCAACACCAGAAAATTTAGCAGAACAAATTAAAAAAGCAGATGTATTTATTTCTACAATT
TTAATTCCTGGTGCGAAACCGCCAAAATTGGTTACTCGTGAGATGGTTAAATCAATGAAAAAAGGTTCAGTATTAATCGA
TATAGCTATTGACCAAGGTGGAACTATTGAAACAATTAGACCAACTACAATTTCTGATCCAGTGTATGAAGAAGAAGGTG
TGATTCATTATGGTGTACCAAATCAACCAGGAGCAGTCCCAAGAACTTCAACAATGGCATTAGCACAAGGAAATATTGAT
TATATATTAGAAATTTGTGACAAAGGCTTAGAACAAGCAATTAAAGATAATGAAGCATTAAGTGCTGGTGTAAACATTTA
CCAAGGACAAGAGACAAATCAAGGATTAGCTACATCACATGACCTAGATTATAAAGAAATATTAAATGTTATCGAATAG

Upstream 100 bases:

>100_bases
ATAGATAAAATATGAATAATTAATTAATGGTATTACATATTCATAACCAAAGGATAAAATAATTGTGAAATTATTCACAA
ACGAAAGAGGAGTGTTGCAA

Downstream 100 bases:

>100_bases
ATAGTAATTTAAATGAAATTGAGTGAAATGAATATTTTAAATATAGCATTATAGTTTGGACTAAAAATTTACAAAACGGA
AGGATGTAATTATTATGACA

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLVAVVKELKQGEGRVACTPENVRKLTAAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQGVGVIAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSAGVNIYQGQETNQGLATSHDLDYKEILNVIE

Sequences:

>Translated_372_residues
MLVAVVKELKQGEGRVACTPENVRKLTAAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQGVGVIAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSAGVNIYQGQETNQGLATSHDLDYKEILNVIE
>Mature_372_residues
MLVAVVKELKQGEGRVACTPENVRKLTAAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQGVGVIAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSAGVNIYQGQETNQGLATSHDLDYKEILNVIE

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=359, Percent_Identity=29.8050139275766, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI122939153, Length=359, Percent_Identity=29.8050139275766, Blast_Score=130, Evalue=1e-30,
Organism=Escherichia coli, GI1787887, Length=352, Percent_Identity=28.9772727272727, Blast_Score=128, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17550456, Length=346, Percent_Identity=29.7687861271676, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 40145; Mature: 40145

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVAVVKELKQGEGRVACTPENVRKLTAAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTH
CHHHHHHHHHCCCCEEEECHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHCCCEEEEE
EQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQGVGVIAISGETIIK
CCCCCCEEEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCEEEEECCCEEEE
NGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCEEE
TNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
CCCCEEEEECCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHEEEEE
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVP
EECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCC
NQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSAGVNIYQGQETNQGLATSH
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCCCCCCCCC
DLDYKEILNVIE
CCCHHHHHHHCC
>Mature Secondary Structure
MLVAVVKELKQGEGRVACTPENVRKLTAAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTH
CHHHHHHHHHCCCCEEEECHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHCCCEEEEE
EQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQGVGVIAISGETIIK
CCCCCCEEEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCEEEEECCCEEEE
NGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCEEE
TNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
CCCCEEEEECCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHEEEEE
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVP
EECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCC
NQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSAGVNIYQGQETNQGLATSH
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCCCCCCCCC
DLDYKEILNVIE
CCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA