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The map label for this gene is tdcB

Identifier: 82751038

GI number: 82751038

Start: 1426440

End: 1427342

Strand: Reverse

Name: tdcB

Synonym: SAB1303c

Alternate gene names: 82751038

Gene position: 1427342-1426440 (Counterclockwise)

Preceding gene: 82751039

Following gene: 82751037

Centisome position: 52.04

GC content: 34.66

Gene sequence:

>903_bases
ATGACAACCAACACAGTTACATTACAAACAGCACATATTGTAAGTTTAGGAGATATCGAAGAAGCTAAAGCAAGCATTAA
ACCATTTATTCGTCGAACACCTCTAATTAAATCAATGTATTTAAGCCAAAGTATAACTAAAGGGAATGTATTTCTAAAAT
TAGAAAATATGCAATTCACAGGATCTTTTAAATTTAGAGGCGCTAGCAATAAAATTAATCACTTAACAGATGAACAAAAA
GAAAAAGGCATTATCGCAGCATCTGCTGGGAACCATGCACAAGGTGTTGCTTTAACAGCTAAATTATTAGGCATTGATGC
AACTATCGTAATGCCTGAAACAGCACCACAAGCGAAACAACAAGCAACAAAAGGCTATGGGACAAAGGTTATTTTAAAAG
GTAAAAACTTTAACGAAACTAGACTTTATATGGAAGAATTAGCGAAAGAAAATGGCATGACAATCGTTCATCCATATGAC
GATAAGTTTGTAATGGCAGGCCAAGGAACAATTGGTTTAGAAATTTTAGATGATATTTGGAATGTGAATACAGTCATCGT
ACCAGTTGGCGGTGGAGGATTAATTGCAGGTATTGCCACCGCATTAAAATCATTTAACCCTTCAATTCATATTATCGGTG
TTCAATCTGAGAATGTTCATGGTATGGCTGAGTCTTTCTATAAAAGAGATTTAACTGAACATCGAGTGGATAGCACAATA
GCAGATGGTTGTGATGTAAAAGTTCCTGGTGAACAAACATATGAAGTAGTTAAACATTTAGTAGATGAATTTATTCTTGT
TATTGAAGAAGAAATTGAACATGCTATGAAAGATTTAATGCAGCGTGCCAAGATTATTACTGAAGGTGCAGGCGCATTAC
CAACAGCTGCAATTTTAAGTTGA

Upstream 100 bases:

>100_bases
GAATAGATAGTAATTTAAATGAAATTGAGTGAAATGAATATTTTAAATATAGCATTATAGTTTGGACTAAAAATTTACAA
AACGGAAGGATGTAATTATT

Downstream 100 bases:

>100_bases
AAAATAAACAATAAATGGCTTGAAGATAAAAATGTTGTTGCTTTAGTTTCAGGCGGGAATGTTGACTTAACTAGAGTTTC
AGGTGTCATTGAACATGGAC

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTTNTVTLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQSITKGNVFLKLENMQFTGSFKFRGASNKINHLTDEQK
EKGIIAASAGNHAQGVALTAKLLGIDATIVMPETAPQAKQQATKGYGTKVILKGKNFNETRLYMEELAKENGMTIVHPYD
DKFVMAGQGTIGLEILDDIWNVNTVIVPVGGGGLIAGIATALKSFNPSIHIIGVQSENVHGMAESFYKRDLTEHRVDSTI
ADGCDVKVPGEQTYEVVKHLVDEFILVIEEEIEHAMKDLMQRAKIITEGAGALPTAAILS

Sequences:

>Translated_300_residues
MTTNTVTLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQSITKGNVFLKLENMQFTGSFKFRGASNKINHLTDEQK
EKGIIAASAGNHAQGVALTAKLLGIDATIVMPETAPQAKQQATKGYGTKVILKGKNFNETRLYMEELAKENGMTIVHPYD
DKFVMAGQGTIGLEILDDIWNVNTVIVPVGGGGLIAGIATALKSFNPSIHIIGVQSENVHGMAESFYKRDLTEHRVDSTI
ADGCDVKVPGEQTYEVVKHLVDEFILVIEEEIEHAMKDLMQRAKIITEGAGALPTAAILS
>Mature_299_residues
TTNTVTLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQSITKGNVFLKLENMQFTGSFKFRGASNKINHLTDEQKE
KGIIAASAGNHAQGVALTAKLLGIDATIVMPETAPQAKQQATKGYGTKVILKGKNFNETRLYMEELAKENGMTIVHPYDD
KFVMAGQGTIGLEILDDIWNVNTVIVPVGGGGLIAGIATALKSFNPSIHIIGVQSENVHGMAESFYKRDLTEHRVDSTIA
DGCDVKVPGEQTYEVVKHLVDEFILVIEEEIEHAMKDLMQRAKIITEGAGALPTAAILS

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=293, Percent_Identity=36.1774744027304, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI19923959, Length=155, Percent_Identity=39.3548387096774, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI33469958, Length=158, Percent_Identity=32.9113924050633, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1789505, Length=275, Percent_Identity=54.9090909090909, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1790207, Length=271, Percent_Identity=40.590405904059, Blast_Score=161, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71991565, Length=286, Percent_Identity=40.9090909090909, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17537387, Length=280, Percent_Identity=36.4285714285714, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17508781, Length=289, Percent_Identity=30.4498269896194, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320930, Length=279, Percent_Identity=42.6523297491039, Blast_Score=190, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6322631, Length=287, Percent_Identity=37.9790940766551, Blast_Score=189, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6319788, Length=282, Percent_Identity=24.822695035461, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355833, Length=275, Percent_Identity=39.2727272727273, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24645328, Length=178, Percent_Identity=38.7640449438202, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 32592; Mature: 32461

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNTVTLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQSITKGNVFLKLENMQFT
CCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEECEEEE
GSFKFRGASNKINHLTDEQKEKGIIAASAGNHAQGVALTAKLLGIDATIVMPETAPQAKQ
EEEEECCCCCCHHHCCCHHHHCCEEEECCCCCCCCCEEEEEEECCCEEEEECCCCCHHHH
QATKGYGTKVILKGKNFNETRLYMEELAKENGMTIVHPYDDKFVMAGQGTIGLEILDDIW
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCHHHHHHHHC
NVNTVIVPVGGGGLIAGIATALKSFNPSIHIIGVQSENVHGMAESFYKRDLTEHRVDSTI
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ADGCDVKVPGEQTYEVVKHLVDEFILVIEEEIEHAMKDLMQRAKIITEGAGALPTAAILS
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure 
TTNTVTLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQSITKGNVFLKLENMQFT
CCCEEEEEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEECEEEE
GSFKFRGASNKINHLTDEQKEKGIIAASAGNHAQGVALTAKLLGIDATIVMPETAPQAKQ
EEEEECCCCCCHHHCCCHHHHCCEEEECCCCCCCCCEEEEEEECCCEEEEECCCCCHHHH
QATKGYGTKVILKGKNFNETRLYMEELAKENGMTIVHPYDDKFVMAGQGTIGLEILDDIW
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCHHHHHHHHC
NVNTVIVPVGGGGLIAGIATALKSFNPSIHIIGVQSENVHGMAESFYKRDLTEHRVDSTI
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ADGCDVKVPGEQTYEVVKHLVDEFILVIEEEIEHAMKDLMQRAKIITEGAGALPTAAILS
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA