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The map label for this gene is hisC [H]

Identifier: 82750426

GI number: 82750426

Start: 740318

End: 741376

Strand: Direct

Name: hisC [H]

Synonym: SAB0673

Alternate gene names: 82750426

Gene position: 740318-741376 (Clockwise)

Preceding gene: 82750425

Following gene: 82750427

Centisome position: 26.99

GC content: 33.52

Gene sequence:

>1059_bases
ATGAAAGAACAACTTAATCAACTATCAGCATATCAGCCTGGTTTATCTCCAAGGGCATTGAAAGAAAAGTATGGCATTGA
AGGAGATTTATATAAACTTGCATCAAATGAAAATTTGTATGGACCATCGCCTAAAGTTAAAGAAGCGATATCAGCACACT
TAGATGAGTTATATTATTATCCTGAAACAGGATCACCGACATTAAAAGCGGCGATTAGTAAACATTTAAATGTAGATCAA
TCACGCATTTTATTTGGTGCGGGATTAGATGAAGTTATATTAATGATTTCTAGAGCAGTATTAACACCAGGGGATACTAT
TGTTACAAGTGAAGCGACATTCGGTCAATATTATCACAATGCGATTGTTGAATCAGCTAATGTGATACAAGTACCTTTAA
AAGATGGTGGCTTCGATTTAGAAGGTATTTTAAAACAAGTTAATGAAGATACGTCATTGGTATGGTTATGTAATCCAAAT
AATCCTACAGGTACATATTTTAATCATGAGAGCTTAGATTCGTTTTTATCTCAAGTACCTCCACATGTACCAGTAATTAT
AGATGAAGCTTATTTTGAATTTGTGACAGCAGAGGACTACCCGGATACACTTGCTTTGCAACAAAAATATGACAATGCAT
TCTTATTACGTACATTTTCAAAGGCGTATGGATTAGCCGGTTTACGTGTAGGATATGTGGTAGCAAGCGAACATGCGATT
GAAAAATGGAACATCATTAGACCACCATTTAATGTGACACGTATATCTGAATACGCAGCAGTTGCAGCACTTGAAGATCA
ACAATATTTAAAAGAGGTAACACATAAAAATAGTGTTGAACGCGAAAGATTTTATCAATTACCTCAAAGTAAGCATTTCT
TACCAAGTCAAACGAATTTTATATTTGTAAAAACAAAGCGGGTAAATGAACTTTATGAAGCACTTTTAAATGTAGGGTGT
ATTACGCGACCATTTCCAACTGGTGTTAGAATTACAATTGGTTTTAAAGAACAAAATGATAAAATGTTAGAAGTTTTATC
AAACTTTAAATACGAATAG

Upstream 100 bases:

>100_bases
TGATGTGAAAATAGTAGCATTGCATTTTAGAAACATAGAGCGATATAATGAATATAAGTTTTTTAAAATTTCAGTTAATT
CTAAGGAGGTTGTTTTTATT

Downstream 100 bases:

>100_bases
TAAGTGTTGTCACATTGTATAAAAATGTGACTAAATGCAGTGTGAATGATGAGGTGAGAGTATTCAGTGTAAAAAGCAAC
AATAGATGATATTGTTTTGT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQ
SRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKQVNEDTSLVWLCNPN
NPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAI
EKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSKHFLPSQTNFIFVKTKRVNELYEALLNVGC
ITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE

Sequences:

>Translated_352_residues
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQ
SRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKQVNEDTSLVWLCNPN
NPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAI
EKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSKHFLPSQTNFIFVKTKRVNELYEALLNVGC
ITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>Mature_352_residues
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQ
SRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKQVNEDTSLVWLCNPN
NPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAI
EKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSKHFLPSQTNFIFVKTKRVNELYEALLNVGC
ITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=348, Percent_Identity=28.735632183908, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788722, Length=239, Percent_Identity=25.5230125523013, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322075, Length=352, Percent_Identity=26.4204545454545, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39760; Mature: 39760

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYY
CCHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHEEC
PETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHN
CCCCCHHHHHHHHHHCCCCHHHEEEECCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHH
AIVESANVIQVPLKDGGFDLEGILKQVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVP
HHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
PHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAI
CCCCEEECCHHHHEEECCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCHHH
EKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSKHFLPSQTNF
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCE
IFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
EEEEEHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYY
CCHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHEEC
PETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHN
CCCCCHHHHHHHHHHCCCCHHHEEEECCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHH
AIVESANVIQVPLKDGGFDLEGILKQVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVP
HHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCC
PHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAI
CCCCEEECCHHHHEEECCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCHHH
EKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSKHFLPSQTNF
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCE
IFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
EEEEEHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA