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The map label for this gene is ltaS [H]

Identifier: 82750421

GI number: 82750421

Start: 731486

End: 733426

Strand: Direct

Name: ltaS [H]

Synonym: SAB0668

Alternate gene names: 82750421

Gene position: 731486-733426 (Clockwise)

Preceding gene: 82750420

Following gene: 82750422

Centisome position: 26.67

GC content: 31.17

Gene sequence:

>1941_bases
ATGAGTTCACAAAAAAAGAAAATTAGTCTTTTTGCGTTCTTTTTATTAACCGTAATAACGATTACCTTGAAGACGTATTT
TTCTTATTATGTTGATTTTTCTTTAGGTGTTAAAGGTTTAGTACAAAACTTAATATTATTGATGAATCCTTATAGTTTAG
TAGCACTGGTTTTAAGTGTGTTCCTATTCTTTAAAGGCAAAAAAGCATTTTGGTTCATGTTCATAGGTGGCTTCTTATTG
ACGTTCCTATTATATGCCAATGTTGTGTACTTTAGATTCTTCTCGGATTTTTTAACGTTTAGTACTTTAAACCAAGTAGG
TAACGTAGAATCTATGGGTGGTGCGGTTAGTGCATCATTCAAATGGTATGACTTTGTTTATTTCATTGATACGTTAGTTT
ACTTATTCATTTTAATATTTAAAACAAAATGGTTAGACACAAAAGCATTTAGTAAGAAATTTGTTCCTGTCGTAATGGCG
GCTTCAGTAGCATTATTCTTCTTAAACTTAGCTTTTGCTGAAACTGATAGACCAGAATTATTAACACGTACATTTGACCA
TAAATATTTAGTGAAATATTTAGGACCGTATAACTTTACAGTATACGATGGTGTTAAAACTATCGAAAATAATCAACAAA
AAGCGTTAGCATCTGAAGATGACTTAACAAAAGTATTAAATTATACGAAACAACGTCAAACAGAGCCTAACCCAGAATAT
TATGGGGTGGCAAAGAAGAAAAATATTATTAAGATTCATTTAGAAAGTTTCCAAACCTTCTTAATTAATAAAAAGGTTAA
TGGTAAAGAAGTAACACCGTTTTTAAACAAATTATCAAGTGGGAAACAGCAATTCACATACTTCCCTAACTTTTTCCATC
AAACAGGTCAAGGTAAAACATCTGACTCTGAATTTACAATGGATAACAGTTTATACGGTTTACCGCAAGGTTCTGCCTTT
TCATTAAAAGGAGATAATACGTATCAGTCATTACCAGCAATTTTAGATCAAAAGCAAGGCTACAAATCTGATGTCATGCA
CGGTGACTATAAAACATTCTGGAACAGAGACCAAGTATATAAACACTTTGGTATCGATAAATTCTATGATGCAACATACT
ATGACATGTCAGATAAAAACGTTGTAAACTTAGGCTTGAAAGACAAAATTTTCTTTAAAGATTCTGCTAATTATCAAGCT
AAGATGAAATCACCATTCTATTCTCATTTAATTACATTGACTAACCACTATCCATTCACATTAGATGAAAAGGATGCAAC
TATTGAGAAGTCAAACACAGGTGATGCAACAGTTGATGGTTATATTCAAACAGCGCGTTATTTAGACGAAGCATTAGAAG
AATATATTAATGACTTGAAGAAAAAAGGATTATATGACAATTCAGTGATTATGATTTATGGTGACCACTATGGTATCTCT
GAAAACCATAACAATGCCATGGAAAAACTATTAGGTGAAAAAATCACACCGGCTAAATTTACAGATTTAAACAGAACTGG
TTTCTGGATTAAAATCCCTGGTAAATCTGGTGGTATCAATAACGAATATGCTGGTCAAGTCGATGTAATGCCAACAATTT
TACATTTGGCTGGTATAGATACGAAGAACTATTTAATGTTCGGTACTGATTTATTCTCTAAAGGTCATAATCAAGTAGTT
CCATTCAGAAATGGTGACTTTATAACAAAAGATTATAAATATGTTAATGGTAAGATTTATTCTAATAAAAATAATGAACT
CATAACTACTCAACCAGCTGATTTCGAAAAGAATAAAAAGCAAGTTGAAAAGGATCTCGAAATGAGTGACAACGTGCTTA
ATGGTGATTTGTTTAGATTCTACAAAAATCCAGACTTCAAAAAGGTAAATCCTTCGAAGTATAAATATGAAACAGGACCT
AAAGCAAACTCTAAAAAATAA

Upstream 100 bases:

>100_bases
AACTTTTAAACGCACTTATTAATTAACTACATAATGTTAATATCTAATTTATTCAAGTACTTTCGCAAGATTTATTATCT
AAATAACGGGGGAAAGAATC

Downstream 100 bases:

>100_bases
TATCTAAACACGAACTCGGATTGATAAAATATCAATCCGGGTTTTTATTATGATCTTTTATATTATGTTTTACATTATAT
GTGTTGATAAAAAGGTATAT

Product: transmembrane sulfatase

Products: NA

Alternate protein names: LTA synthase; Polyglycerol phosphate synthase [H]

Number of amino acids: Translated: 646; Mature: 645

Protein sequence:

>646_residues
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLL
TFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMA
ASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKQQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAF
SLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQA
KMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVV
PFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGP
KANSKK

Sequences:

>Translated_646_residues
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLL
TFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMA
ASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKQQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAF
SLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQA
KMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVV
PFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGP
KANSKK
>Mature_645_residues
SSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLT
FLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAA
SVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYY
GVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKQQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFS
LKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAK
MKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISE
NHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVP
FRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPK
ANSKK

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Is required for staphylococcal growth and cell division process [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase:Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 74400; Mature: 74269

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEECCC
KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
HHHHCCHHHHHHHCCCCCEEEECCHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCE
YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKQQFTYFPNFFHQTGQGKT
EEECCCCCEEEEEHHHHHHHHEECCCCCCHHHHHHHHHCCCCCEEEECCHHHHHCCCCCC
SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
CCCCEEECCCEECCCCCCEEEECCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHCCHHHHH
KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
HHCCCCHHCCCEEEECCCCCEEEECCCCEEEEECCCCCCEECCCCHHHHHHHHCCCCCEE
LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
ECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
CCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
CCCEEEEEHHHHHCCCCEEECCCCCCEEECCEEEECCEEEECCCCCEEEECCCCCHHHHH
QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
HHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
SSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEECCC
KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
HHHHCCHHHHHHHCCCCCEEEECCHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCE
YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKQQFTYFPNFFHQTGQGKT
EEECCCCCEEEEEHHHHHHHHEECCCCCCHHHHHHHHHCCCCCEEEECCHHHHHCCCCCC
SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
CCCCEEECCCEECCCCCCEEEECCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHCCHHHHH
KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
HHCCCCHHCCCEEEECCCCCEEEECCCCEEEEECCCCCCEECCCCHHHHHHHHCCCCCEE
LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
ECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
CCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
CCCEEEEEHHHHHCCCCEEECCCCCCEEECCEEEECCEEEECCCCCEEEECCCCCHHHHH
QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
HHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA