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The map label for this gene is nagA [H]

Identifier: 82750403

GI number: 82750403

Start: 715528

End: 716709

Strand: Direct

Name: nagA [H]

Synonym: SAB0650

Alternate gene names: 82750403

Gene position: 715528-716709 (Clockwise)

Preceding gene: 82750402

Following gene: 82750404

Centisome position: 26.09

GC content: 36.63

Gene sequence:

>1182_bases
GTGTCAGAATTAATTATATATAACGGCAAAGTTTATACTGAAGATGGCAAAATCGATAATGGTTACATTCATGTGAAAGA
TGGGCAGATTGTTGCAATTGGAGAAGTAAATGATAAAGCAGCGACTGATAATGATACGACAAATAAAATTCAAGTGATGG
ATGCAAAAGGTCATCATGTAGTGCCAGGTTTTATCGATATACATATTCATGGTGGTTATGGACAGGATGCAATGGATGGG
TCATACGATGGCTTAAAATATCTATCCGAAAATTTGTTGTCTGAAGGGACGACATCATACTTGGCCACTACAATGACGCA
ATCGACTGATAAAATAGATAAAGCACTTATAAATATTGCTAAATATGAAGTGGAGCAAGATGTTCACAATGCAGCGGAAA
TTGTAGGTATACATTTGGAAGGGCCATTTATATCTGAAAATAAAGTTGGTGCTCAACATCCGCAATACGTTGTACGCCCA
TTTATCGATAAAATTAAACATTTTCAAGAGATTGCTAACGGATTAATAAAGATTATGACGTTTGCACCTGAAGTTGAAGG
TGCAAAAGAAGCGCTTGAAACGTATAAAGATGACATTATTTTTTCAATTGGTCATACAGTGGCAACATACGAAGAAGCAG
TTGAAGCTGTTGAGCGAGGAGCTAAACATGTCACGCATTTATATAATGCAGCGACGCCATTCCAACATAGAGAACCAGGT
GTTTTTGGAGCAGCATGGTTGAATGATGCTTTACATACCGAAATGATTGTTGATGGCACACATTCTCATCCGGCATCGGT
TGCAATTGCTTACCGTATGAAAGGTAATGAACGTTTTTATTTAATTACCGATGCAATGCGTGCAAAAGGTATGCCTGAGG
GAGAATATGATTTGGGTGGTCAAAAAGTAACTGTTCAATCGCAACAAGCACGTCTTGCAAATGGTGCGCTTGCTGGTAGT
ATTTTAAAAATGAATCATGGGTTACGTAACTTAATATCATTTACAGGTGATACATTAGATCATTTATGGCGTGTAACAAG
TTTAAATCAAGCCATTGCACTAGGTATCGATGATAGAAAAGGTAGTATTAAAGTAAATAAGGATGCAGATCTTGTTATTC
TAGATGAGGACATGAATGTAAAATCTACAATAAAACAAGGTAAGGTTCACACATTTAGCTAA

Upstream 100 bases:

>100_bases
ACTTTTTTAATATTTTGCAAAAAGTTATGCCAAACGAAGCAGATATAGTAAAATATGAGTGTCTTAAAGTGAAAATTTAT
AAATAAAGAAGGGTTTATAC

Downstream 100 bases:

>100_bases
TAGATAATCATAATTAAATGTATGCAATAGATTTAATCTGTTAACATAAGCACTTTATATTATGATAAAATAGAAGCAAT
AACATTTTTTTCTGGGGATG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSELIIYNGKVYTEDGKIDNGYIHVKDGQIVAIGEVNDKAATDNDTTNKIQVMDAKGHHVVPGFIDIHIHGGYGQDAMDG
SYDGLKYLSENLLSEGTTSYLATTMTQSTDKIDKALINIAKYEVEQDVHNAAEIVGIHLEGPFISENKVGAQHPQYVVRP
FIDKIKHFQEIANGLIKIMTFAPEVEGAKEALETYKDDIIFSIGHTVATYEEAVEAVERGAKHVTHLYNAATPFQHREPG
VFGAAWLNDALHTEMIVDGTHSHPASVAIAYRMKGNERFYLITDAMRAKGMPEGEYDLGGQKVTVQSQQARLANGALAGS
ILKMNHGLRNLISFTGDTLDHLWRVTSLNQAIALGIDDRKGSIKVNKDADLVILDEDMNVKSTIKQGKVHTFS

Sequences:

>Translated_393_residues
MSELIIYNGKVYTEDGKIDNGYIHVKDGQIVAIGEVNDKAATDNDTTNKIQVMDAKGHHVVPGFIDIHIHGGYGQDAMDG
SYDGLKYLSENLLSEGTTSYLATTMTQSTDKIDKALINIAKYEVEQDVHNAAEIVGIHLEGPFISENKVGAQHPQYVVRP
FIDKIKHFQEIANGLIKIMTFAPEVEGAKEALETYKDDIIFSIGHTVATYEEAVEAVERGAKHVTHLYNAATPFQHREPG
VFGAAWLNDALHTEMIVDGTHSHPASVAIAYRMKGNERFYLITDAMRAKGMPEGEYDLGGQKVTVQSQQARLANGALAGS
ILKMNHGLRNLISFTGDTLDHLWRVTSLNQAIALGIDDRKGSIKVNKDADLVILDEDMNVKSTIKQGKVHTFS
>Mature_392_residues
SELIIYNGKVYTEDGKIDNGYIHVKDGQIVAIGEVNDKAATDNDTTNKIQVMDAKGHHVVPGFIDIHIHGGYGQDAMDGS
YDGLKYLSENLLSEGTTSYLATTMTQSTDKIDKALINIAKYEVEQDVHNAAEIVGIHLEGPFISENKVGAQHPQYVVRPF
IDKIKHFQEIANGLIKIMTFAPEVEGAKEALETYKDDIIFSIGHTVATYEEAVEAVERGAKHVTHLYNAATPFQHREPGV
FGAAWLNDALHTEMIVDGTHSHPASVAIAYRMKGNERFYLITDAMRAKGMPEGEYDLGGQKVTVQSQQARLANGALAGSI
LKMNHGLRNLISFTGDTLDHLWRVTSLNQAIALGIDDRKGSIKVNKDADLVILDEDMNVKSTIKQGKVHTFS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI224922791, Length=382, Percent_Identity=32.4607329842932, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI21361513, Length=382, Percent_Identity=32.1989528795811, Blast_Score=179, Evalue=5e-45,
Organism=Escherichia coli, GI1786892, Length=386, Percent_Identity=29.0155440414508, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17553768, Length=405, Percent_Identity=31.6049382716049, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI19920392, Length=396, Percent_Identity=32.0707070707071, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI281361140, Length=410, Percent_Identity=31.219512195122, Blast_Score=181, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 43187; Mature: 43056

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELIIYNGKVYTEDGKIDNGYIHVKDGQIVAIGEVNDKAATDNDTTNKIQVMDAKGHHV
CCCEEEECCEEEECCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCEEEEEECCCCEE
VPGFIDIHIHGGYGQDAMDGSYDGLKYLSENLLSEGTTSYLATTMTQSTDKIDKALINIA
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
KYEVEQDVHNAAEIVGIHLEGPFISENKVGAQHPQYVVRPFIDKIKHFQEIANGLIKIMT
HHHHHHHHHCCEEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEHH
FAPEVEGAKEALETYKDDIIFSIGHTVATYEEAVEAVERGAKHVTHLYNAATPFQHREPG
CCCCCCHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VFGAAWLNDALHTEMIVDGTHSHPASVAIAYRMKGNERFYLITDAMRAKGMPEGEYDLGG
CEEHHHHHHHHHHEEEEECCCCCCCEEEEEEEECCCCEEEEEEHHHHHCCCCCCCCCCCC
QKVTVQSQQARLANGALAGSILKMNHGLRNLISFTGDTLDHLWRVTSLNQAIALGIDDRK
CEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCC
GSIKVNKDADLVILDEDMNVKSTIKQGKVHTFS
CCEEECCCCCEEEECCCCCHHHHHHCCCEECCC
>Mature Secondary Structure 
SELIIYNGKVYTEDGKIDNGYIHVKDGQIVAIGEVNDKAATDNDTTNKIQVMDAKGHHV
CCEEEECCEEEECCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCEEEEEECCCCEE
VPGFIDIHIHGGYGQDAMDGSYDGLKYLSENLLSEGTTSYLATTMTQSTDKIDKALINIA
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
KYEVEQDVHNAAEIVGIHLEGPFISENKVGAQHPQYVVRPFIDKIKHFQEIANGLIKIMT
HHHHHHHHHCCEEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEHH
FAPEVEGAKEALETYKDDIIFSIGHTVATYEEAVEAVERGAKHVTHLYNAATPFQHREPG
CCCCCCHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VFGAAWLNDALHTEMIVDGTHSHPASVAIAYRMKGNERFYLITDAMRAKGMPEGEYDLGG
CEEHHHHHHHHHHEEEEECCCCCCCEEEEEEEECCCCEEEEEEHHHHHCCCCCCCCCCCC
QKVTVQSQQARLANGALAGSILKMNHGLRNLISFTGDTLDHLWRVTSLNQAIALGIDDRK
CEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCC
GSIKVNKDADLVILDEDMNVKSTIKQGKVHTFS
CCEEECCCCCEEEECCCCCHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]