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The map label for this gene is hchA [H]

Identifier: 82750259

GI number: 82750259

Start: 563603

End: 564481

Strand: Direct

Name: hchA [H]

Synonym: SAB0502

Alternate gene names: 82750259

Gene position: 563603-564481 (Clockwise)

Preceding gene: 82750258

Following gene: 82750260

Centisome position: 20.55

GC content: 34.58

Gene sequence:

>879_bases
ATGTCACAAGATGTAAATGAATTAAGTAAGCAACCAACGCCAGATAAAGCAGAAGATAACGCATTTTTCCCATCACCATA
TTCCCTTAGTCAATATACAGCACCTAAAACAGATTTTGATGGTGTTGAACACAAAGGTGCCTATAAAGATGGTAAATGGA
AAGTATTGATGATTGCTGCTGAAGAGAGATATGTATTATTGGAAAATGGAAAAATGTTCTCTACGGGTAATCATCCTGTT
GAAATGTTATTACCTTTACATCATTTAATGGAAGCAGGTTTTGACGTTGATGTTGCGACATTATCTGGTTATCCAGCTAA
ATTAGAATTATGGGCTATGCCAACTGAAGACGAGGCAGTTATAACCACTTATAATAAATTGAAAGAAAAATTAAAACAGC
CAAAAAAATTAGCAGATGTGATTAAAAATGAATTAGGACCTGATTCAGACTATTTATCTGTCTTTATCCCAGGTGGACAT
GCTGCAGTTGTTGGTATTTCTGAAAGCGAAGACGTTCAAAAAACATTAGATTGGGCATTAGAAAATGACCGCTTTATAGT
TACATTATGTCATGGACCAGCAGCACTACTTTCAGCAGGGCTTAACAGAGAAAAATCTCCATTAGAAGGATACTCTGTTT
GTGTCTTCCCTGACTCATTAGATGAAGGTGCAAATATTGAAATAGGTTATTTACCTGGACGCTTGAAATGGTTAGTTGCT
GAGTTATTAACTAAACAAGGATTAAAAGTAGTCAACGACGATATGACAGGAAGAACGTTAAAAGATCGCAAATTATTAAC
AGGTGACAGTCCTTTAGCTTCAAATGAGTTAGGAAAATTAGCAGTTAATGAAATGTTAAATGCAATACAAAATAAATAA

Upstream 100 bases:

>100_bases
ATTAGTTTTGATAATGAGCGTTTTAATAGTAATACATGTTTATAGTGTGTAGTATATGTCTATACTAATAGTAACTATAT
AGAGAAAGTAGGAATAAACT

Downstream 100 bases:

>100_bases
TTAAATATAAATTAGGGGAGCCCCATATGTAAATGTATGAGGGCTCTTTTTTTTGGCAAAATTTAAGTGATACTTGTAAA
ATAGAACCTATTATGAGTAT

Product: chaperone protein HchA

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPV
EMLLPLHHLMEAGFDVDVATLSGYPAKLELWAMPTEDEAVITTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGH
AAVVGISESEDVQKTLDWALENDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVA
ELLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK

Sequences:

>Translated_292_residues
MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPV
EMLLPLHHLMEAGFDVDVATLSGYPAKLELWAMPTEDEAVITTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGH
AAVVGISESEDVQKTLDWALENDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVA
ELLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
>Mature_291_residues
SQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVE
MLLPLHHLMEAGFDVDVATLSGYPAKLELWAMPTEDEAVITTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHA
AVVGISESEDVQKTLDWALENDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVAE
LLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788278, Length=282, Percent_Identity=56.3829787234042, Blast_Score=333, Evalue=6e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 32191; Mature: 32060

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAA
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
EERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPAKLELWAMPTEDEAV
CCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEE
ITTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQKTLDWAL
EHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHC
ENDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVA
CCCCEEEEEECCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHH
ELLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
HHHHHCCCEEECCCCCCCEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAA
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
EERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPAKLELWAMPTEDEAV
CCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEE
ITTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQKTLDWAL
EHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHC
ENDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVA
CCCCEEEEEECCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHH
ELLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
HHHHHCCCEEECCCCCCCEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA