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The map label for this gene is coaX

Identifier: 82703201

GI number: 82703201

Start: 2373450

End: 2374238

Strand: Reverse

Name: coaX

Synonym: Nmul_A2081

Alternate gene names: 82703201

Gene position: 2374238-2373450 (Counterclockwise)

Preceding gene: 82703202

Following gene: 82703200

Centisome position: 74.56

GC content: 59.57

Gene sequence:

>789_bases
ATGAACCCTCTTCTGCTGGCGGTGGATTCCGGCAACACGCGCGTGAAGTGGGGGCTGCATGATGGCCGCAACTGGCTCAT
GCAAGGGGTCGCGGCGCAGGGCGACAGAGTGCAGCTCGAGCGGGAATGGAGGGATTTGCGTGAACCTTCACGCGTAGTGA
TATCCAATGTCGCCAATGCCGGGGTCAAGGGCAGTCTGTCGGAGCTACTGGCGCAGTGGAAAGCGGAGCCACAATGGATT
ACTGCCGTTCCCTATCAATGCGGGGTTCGCAACTATTACTCCAATCCTGCCCAGCTTGGCAGCGACCGCTGGGCGGCGCT
CGTGGCAGCGTGGGTGCTGGAGCGACAGGGGTGCCTGGTAGTCGATGCGGGAACCGCCATGACGGTGGATGCGCTTTCCG
ACACAGGTGAATTTCTCGGAGGACTCATAACCCCCGGGCTCGATCTGATGCAGAAGATACTGGTGGAGGACCTTGGATCA
CTGGAATCGGAGGGCGGAAAATTTTGCGATTATCCTGACAGTACCGCAGATGCGCTCTATAGCGGCGCGGTGCACGCGAT
GGCGGGCGCCATCGAACGCATGGCGGCCTTGCTTGCCGGTACCCTCGGCCACATGCCCGAGTGCATTCTCAGCGGGGGTG
CAGCGCAGCAGTTGCAGCCCCAGCTTAACGTGAATGTGAAAGTGATGGATAATCTCGTTTTGCAAGGCTTGCTGGCCATT
GCCCGGGAGACTTCAGAAACAGCTTCGGGAGGGGTCGTAGCTTCCCCGGAAGATTCCATCGAAAATTGA

Upstream 100 bases:

>100_bases
GGTGCACGGGGTATCGGATAGCGGGTCGCTGTTGCTGCAAACGTCACTGGGTCTTCGCAGTTTCAGCGGCGGCGAGATAT
CGCTGCGCAGGACAGCATAA

Downstream 100 bases:

>100_bases
TCTGCTTTTGCGTCCTGCGGACGTAGACTGGATATGTCCGTTTTTCAGAACGCAACCTTTTACACTACCGTCAACGAGCT
GCGCGACCTGCCCCCCCCGG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNPLLLAVDSGNTRVKWGLHDGRNWLMQGVAAQGDRVQLEREWRDLREPSRVVISNVANAGVKGSLSELLAQWKAEPQWI
TAVPYQCGVRNYYSNPAQLGSDRWAALVAAWVLERQGCLVVDAGTAMTVDALSDTGEFLGGLITPGLDLMQKILVEDLGS
LESEGGKFCDYPDSTADALYSGAVHAMAGAIERMAALLAGTLGHMPECILSGGAAQQLQPQLNVNVKVMDNLVLQGLLAI
ARETSETASGGVVASPEDSIEN

Sequences:

>Translated_262_residues
MNPLLLAVDSGNTRVKWGLHDGRNWLMQGVAAQGDRVQLEREWRDLREPSRVVISNVANAGVKGSLSELLAQWKAEPQWI
TAVPYQCGVRNYYSNPAQLGSDRWAALVAAWVLERQGCLVVDAGTAMTVDALSDTGEFLGGLITPGLDLMQKILVEDLGS
LESEGGKFCDYPDSTADALYSGAVHAMAGAIERMAALLAGTLGHMPECILSGGAAQQLQPQLNVNVKVMDNLVLQGLLAI
ARETSETASGGVVASPEDSIEN
>Mature_262_residues
MNPLLLAVDSGNTRVKWGLHDGRNWLMQGVAAQGDRVQLEREWRDLREPSRVVISNVANAGVKGSLSELLAQWKAEPQWI
TAVPYQCGVRNYYSNPAQLGSDRWAALVAAWVLERQGCLVVDAGTAMTVDALSDTGEFLGGLITPGLDLMQKILVEDLGS
LESEGGKFCDYPDSTADALYSGAVHAMAGAIERMAALLAGTLGHMPECILSGGAAQQLQPQLNVNVKVMDNLVLQGLLAI
ARETSETASGGVVASPEDSIEN

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_NITMU (Q2Y796)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412767.1
- ProteinModelPortal:   Q2Y796
- SMR:   Q2Y796
- STRING:   Q2Y796
- GeneID:   3786085
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2081
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   RTTIRSR
- ProtClustDB:   PRK13329
- BioCyc:   NMUL323848:NMUL_A2081-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27916; Mature: 27916

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: ACT_SITE 102-102 BINDING 93-93 BINDING 125-125 BINDING 175-175

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLLLAVDSGNTRVKWGLHDGRNWLMQGVAAQGDRVQLEREWRDLREPSRVVISNVANA
CCCEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHHHHHHCC
GVKGSLSELLAQWKAEPQWITAVPYQCGVRNYYSNPAQLGSDRWAALVAAWVLERQGCLV
CCCCCHHHHHHHHCCCCCEEEECCHHHCHHHHCCCHHHCCCHHHHHHHHHHHHHCCCEEE
VDAGTAMTVDALSDTGEFLGGLITPGLDLMQKILVEDLGSLESEGGKFCDYPDSTADALY
EECCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
SGAVHAMAGAIERMAALLAGTLGHMPECILSGGAAQQLQPQLNVNVKVMDNLVLQGLLAI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHH
ARETSETASGGVVASPEDSIEN
HHHHCHHCCCCEEECCHHCCCC
>Mature Secondary Structure
MNPLLLAVDSGNTRVKWGLHDGRNWLMQGVAAQGDRVQLEREWRDLREPSRVVISNVANA
CCCEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHHHHHHCC
GVKGSLSELLAQWKAEPQWITAVPYQCGVRNYYSNPAQLGSDRWAALVAAWVLERQGCLV
CCCCCHHHHHHHHCCCCCEEEECCHHHCHHHHCCCHHHCCCHHHHHHHHHHHHHCCCEEE
VDAGTAMTVDALSDTGEFLGGLITPGLDLMQKILVEDLGSLESEGGKFCDYPDSTADALY
EECCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
SGAVHAMAGAIERMAALLAGTLGHMPECILSGGAAQQLQPQLNVNVKVMDNLVLQGLLAI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHH
ARETSETASGGVVASPEDSIEN
HHHHCHHCCCCEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA