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The map label for this gene is sucC [H]

Identifier: 82703117

GI number: 82703117

Start: 2292754

End: 2293950

Strand: Reverse

Name: sucC [H]

Synonym: Nmul_A1996

Alternate gene names: 82703117

Gene position: 2293950-2292754 (Counterclockwise)

Preceding gene: 82703118

Following gene: 82703116

Centisome position: 72.04

GC content: 54.97

Gene sequence:

>1197_bases
ATGAAAATCCATGAATACCAGGCCAAACATATCCTGCATCAGTTTGGTATACCCATACCTCGAGGGCATTCCTGCTTCAA
CGTGGATGAAGCGGTGGCAACCGCTAAAAAACTGGGTGGAAGCACATGGGTGGTCAAGGCCCAAATCCATGCAGGGGGAC
GCGGGAAGGGTGGCGGGGTGAAGATCGCCAGATCGCTTGACGAGGTGAAACAATTTGCCGAAAAAATACTCGGCATGACG
CTCGTCACGCCACAGACGGGTTCGCAGGGTCAGATCGTACGACGGCTGCTGGTCGAACAGGGTCTCGATATCAGGAAGGA
GTTCTACATTGGACTGGTGGTGGATCGGGGCCGCCGCCGTGTCTGCCTGATGGCGAGTGCCGAAGGGGGGATGGATATCG
AGCGGGTCGCTGCCGATTATCCGGAAAAGATCCACAAAGTGTATATCGATCCGGGGGCGGGACTGACCGCTACGGAAGCG
GAAGATATCACGAGCAGGATCGGCTTTTCCGGTGCGGCAGTGGCGGAAACGGCTGCACTGTTGCAGAATCTATACCGCGC
TTACGACAGCACGGACGCATCGCTCGTCGAAATCAATCCGCTGATACTCACCGGCGAAAATCGCATTGTCGCGCTCGATG
CGAAGATGAATTTTGACGATAACGCGCTTTTCCGGCACCCCGATATCGCCGACTTGCGTGATCTTGACGAAGAAGATGCG
GCAGAGATCGAGGCGTCCAGATACGGTCTTTCCTACATCTCGCTCGATGGCAACATAGGTTGCCTGGTAAATGGAGCCGG
TCTTGCAATGGCTACCATGGATATCATCAAGTTCTACGGAGGAAATCCGGCCAATTTTCTCGACGTGGGAGGAGGCGCAA
CCACTGAAAAAGTCATGGAAGCCTTCAAACTGATGCTGCGCAATCCAAGACTGCAAGCCATACTGATCAATATATTCGGG
GGCATCATGAAATGTGATGTCATTGCAGAGGGAGTAGTGGCAGCAGCGCGTGAAGTAAGGTTGAATGTTCCCCTGGTGGT
TCGTCTCGAAGGCACGAATGCGGAGATCGGGAAAAAGATCCTGACCGAATCAGGTCTTGCCATCATTTCAGCCGCGAATA
TGGCGGATGCCGCGGAAAAGGCCGTTACCGCAGCCGCATCAGCCACCTCGGCCGCCATGCCGGCCACAGGGTCGTGA

Upstream 100 bases:

>100_bases
CTCGACGGGGAGGAAGCAGGATGTTCGACCTCTCTTCCTCTCCCCGTAACGCCAATACAACTATTGAGCTATACTCCCTA
TTCACGTCGTTGGAGGTATC

Downstream 100 bases:

>100_bases
ACAGAATCGGCAAACGAGGGAAATCAGTATGGCGATCCTGATCGACCGTAACACTCGTATCATGACGCAGGGGATTACCG
GCAAGACCGGGCAATTCCAC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MKIHEYQAKHILHQFGIPIPRGHSCFNVDEAVATAKKLGGSTWVVKAQIHAGGRGKGGGVKIARSLDEVKQFAEKILGMT
LVTPQTGSQGQIVRRLLVEQGLDIRKEFYIGLVVDRGRRRVCLMASAEGGMDIERVAADYPEKIHKVYIDPGAGLTATEA
EDITSRIGFSGAAVAETAALLQNLYRAYDSTDASLVEINPLILTGENRIVALDAKMNFDDNALFRHPDIADLRDLDEEDA
AEIEASRYGLSYISLDGNIGCLVNGAGLAMATMDIIKFYGGNPANFLDVGGGATTEKVMEAFKLMLRNPRLQAILINIFG
GIMKCDVIAEGVVAAAREVRLNVPLVVRLEGTNAEIGKKILTESGLAIISAANMADAAEKAVTAAASATSAAMPATGS

Sequences:

>Translated_398_residues
MKIHEYQAKHILHQFGIPIPRGHSCFNVDEAVATAKKLGGSTWVVKAQIHAGGRGKGGGVKIARSLDEVKQFAEKILGMT
LVTPQTGSQGQIVRRLLVEQGLDIRKEFYIGLVVDRGRRRVCLMASAEGGMDIERVAADYPEKIHKVYIDPGAGLTATEA
EDITSRIGFSGAAVAETAALLQNLYRAYDSTDASLVEINPLILTGENRIVALDAKMNFDDNALFRHPDIADLRDLDEEDA
AEIEASRYGLSYISLDGNIGCLVNGAGLAMATMDIIKFYGGNPANFLDVGGGATTEKVMEAFKLMLRNPRLQAILINIFG
GIMKCDVIAEGVVAAAREVRLNVPLVVRLEGTNAEIGKKILTESGLAIISAANMADAAEKAVTAAASATSAAMPATGS
>Mature_398_residues
MKIHEYQAKHILHQFGIPIPRGHSCFNVDEAVATAKKLGGSTWVVKAQIHAGGRGKGGGVKIARSLDEVKQFAEKILGMT
LVTPQTGSQGQIVRRLLVEQGLDIRKEFYIGLVVDRGRRRVCLMASAEGGMDIERVAADYPEKIHKVYIDPGAGLTATEA
EDITSRIGFSGAAVAETAALLQNLYRAYDSTDASLVEINPLILTGENRIVALDAKMNFDDNALFRHPDIADLRDLDEEDA
AEIEASRYGLSYISLDGNIGCLVNGAGLAMATMDIIKFYGGNPANFLDVGGGATTEKVMEAFKLMLRNPRLQAILINIFG
GIMKCDVIAEGVVAAAREVRLNVPLVVRLEGTNAEIGKKILTESGLAIISAANMADAAEKAVTAAASATSAAMPATGS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=398, Percent_Identity=43.7185929648241, Blast_Score=342, Evalue=3e-94,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=45.1697127937337, Blast_Score=332, Evalue=4e-91,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=45.0276243093923, Blast_Score=312, Evalue=3e-85,
Organism=Escherichia coli, GI1786948, Length=384, Percent_Identity=50.78125, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=43.765903307888, Blast_Score=334, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.3589743589744, Blast_Score=333, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=43.8775510204082, Blast_Score=335, Evalue=8e-93,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=45.6632653061224, Blast_Score=341, Evalue=5e-94,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=45.6632653061224, Blast_Score=341, Evalue=5e-94,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=44.3877551020408, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI281361397, Length=395, Percent_Identity=45.5696202531646, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI281361395, Length=395, Percent_Identity=45.5696202531646, Blast_Score=337, Evalue=1e-92,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42367; Mature: 42367

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQAKHILHQFGIPIPRGHSCFNVDEAVATAKKLGGSTWVVKAQIHAGGRGKGGGV
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KIARSLDEVKQFAEKILGMTLVTPQTGSQGQIVRRLLVEQGLDIRKEFYIGLVVDRGRRR
HHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCE
VCLMASAEGGMDIERVAADYPEKIHKVYIDPGAGLTATEAEDITSRIGFSGAAVAETAAL
EEEEEECCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHH
LQNLYRAYDSTDASLVEINPLILTGENRIVALDAKMNFDDNALFRHPDIADLRDLDEEDA
HHHHHHHHCCCCCEEEEECEEEEECCCEEEEEEEECCCCCCCEECCCCCHHHHCCCCHHH
AEIEASRYGLSYISLDGNIGCLVNGAGLAMATMDIIKFYGGNPANFLDVGGGATTEKVME
HHHHHHHCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKLMLRNPRLQAILINIFGGIMKCDVIAEGVVAAAREVRLNVPLVVRLEGTNAEIGKKI
HHHHHHCCCCHHEEHEEHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCHHHHHHH
LTESGLAIISAANMADAAEKAVTAAASATSAAMPATGS
HHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKIHEYQAKHILHQFGIPIPRGHSCFNVDEAVATAKKLGGSTWVVKAQIHAGGRGKGGGV
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KIARSLDEVKQFAEKILGMTLVTPQTGSQGQIVRRLLVEQGLDIRKEFYIGLVVDRGRRR
HHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCE
VCLMASAEGGMDIERVAADYPEKIHKVYIDPGAGLTATEAEDITSRIGFSGAAVAETAAL
EEEEEECCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHH
LQNLYRAYDSTDASLVEINPLILTGENRIVALDAKMNFDDNALFRHPDIADLRDLDEEDA
HHHHHHHHCCCCCEEEEECEEEEECCCEEEEEEEECCCCCCCEECCCCCHHHHCCCCHHH
AEIEASRYGLSYISLDGNIGCLVNGAGLAMATMDIIKFYGGNPANFLDVGGGATTEKVME
HHHHHHHCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKLMLRNPRLQAILINIFGGIMKCDVIAEGVVAAAREVRLNVPLVVRLEGTNAEIGKKI
HHHHHHCCCCHHEEHEEHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCHHHHHHH
LTESGLAIISAANMADAAEKAVTAAASATSAAMPATGS
HHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA