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The map label for this gene is prpC [H]

Identifier: 82703118

GI number: 82703118

Start: 2294135

End: 2294869

Strand: Reverse

Name: prpC [H]

Synonym: Nmul_A1997

Alternate gene names: 82703118

Gene position: 2294869-2294135 (Counterclockwise)

Preceding gene: 82703120

Following gene: 82703117

Centisome position: 72.07

GC content: 54.56

Gene sequence:

>735_bases
TTGATCAGCTTACACTCGGCTGGTGCAACCAACGTGGGCCTGTGGCGGGATAACAATGAGGATAGTTATCTGATCATACC
ACAGGCCCGCGTCCTGGCACTCGCAGATGGCATGGGTGGCGCGGCGGCCGGCGAGGTCGCCAGTCAACATTTTGTCGACA
TGGTGCGAATCGCATTTTCCGAACTGGCTTCGCCTCGGAAAGAGAGCGTTTCTGAGCGCATTCAGCATGTATTCGAGCGG
GCAAATGCGCGCATCCTCGAACACATCATCCAGCACCCGGCCGATACAGGAATGGGATGCACAGCAGATCTTCTCGTGTT
CGACGGCGAGCGGTATATTATCGGCCACGTGGGGGATAGCAGAGTTTATCTGCTGCGCGACGGAAGACTGCAGCAGTTGA
CTAAAGATCATTCGCTGGTACAGTCACAGGTGGATAGAGGCATGCTCACGCCCCAGGAGGCAAAGCATCACTTCCGAAAA
AACATTCTCCTGCGCGCCGTGGGAACCGATTCGGCAATAGCATGCGATATCGTGCAAGGGGCGGTGCTCGGCAGCGATAT
TTTTTTATTGTGTTCGGATGGATTGACCGACATGGTGGGGAACGCGGATATCGAAATTGTGCTCGCTTCCGCGGAACCTC
TTGAGCAAAAAGTGGAGAGACTGATCTCGGCAGCTTTGGAAGCTGGGGGAAAAGACAATGTCACCGTGATTCTCTGTGAA
GTAGAGGATGCGTAG

Upstream 100 bases:

>100_bases
CTGCAATGCTCCCCGATATTTGGAGCCACATGCTGCTGCAGGCCGAGAGTCGTGGCCAAGACGGGGGAACACATCGAGCG
ACCAAGCCAAAGGAGCTAAC

Downstream 100 bases:

>100_bases
ATTGCGGTTGAAGGCGGCAGTTATCGGGAATTGCTGGCATTAGCAATTGTCAGTTGTATCAGTAATCCAGAGGGGCAGCT
GCCGCTCGACGGGGAGGAAG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MISLHSAGATNVGLWRDNNEDSYLIIPQARVLALADGMGGAAAGEVASQHFVDMVRIAFSELASPRKESVSERIQHVFER
ANARILEHIIQHPADTGMGCTADLLVFDGERYIIGHVGDSRVYLLRDGRLQQLTKDHSLVQSQVDRGMLTPQEAKHHFRK
NILLRAVGTDSAIACDIVQGAVLGSDIFLLCSDGLTDMVGNADIEIVLASAEPLEQKVERLISAALEAGGKDNVTVILCE
VEDA

Sequences:

>Translated_244_residues
MISLHSAGATNVGLWRDNNEDSYLIIPQARVLALADGMGGAAAGEVASQHFVDMVRIAFSELASPRKESVSERIQHVFER
ANARILEHIIQHPADTGMGCTADLLVFDGERYIIGHVGDSRVYLLRDGRLQQLTKDHSLVQSQVDRGMLTPQEAKHHFRK
NILLRAVGTDSAIACDIVQGAVLGSDIFLLCSDGLTDMVGNADIEIVLASAEPLEQKVERLISAALEAGGKDNVTVILCE
VEDA
>Mature_244_residues
MISLHSAGATNVGLWRDNNEDSYLIIPQARVLALADGMGGAAAGEVASQHFVDMVRIAFSELASPRKESVSERIQHVFER
ANARILEHIIQHPADTGMGCTADLLVFDGERYIIGHVGDSRVYLLRDGRLQQLTKDHSLVQSQVDRGMLTPQEAKHHFRK
NILLRAVGTDSAIACDIVQGAVLGSDIFLLCSDGLTDMVGNADIEIVLASAEPLEQKVERLISAALEAGGKDNVTVILCE
VEDA

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26392; Mature: 26392

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLHSAGATNVGLWRDNNEDSYLIIPQARVLALADGMGGAAAGEVASQHFVDMVRIAFS
CCEECCCCCCCEEEEECCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ELASPRKESVSERIQHVFERANARILEHIIQHPADTGMGCTADLLVFDGERYIIGHVGDS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEECCCC
RVYLLRDGRLQQLTKDHSLVQSQVDRGMLTPQEAKHHFRKNILLRAVGTDSAIACDIVQG
EEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHH
AVLGSDIFLLCSDGLTDMVGNADIEIVLASAEPLEQKVERLISAALEAGGKDNVTVILCE
HHCCCCEEEEECCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEEE
VEDA
ECCC
>Mature Secondary Structure
MISLHSAGATNVGLWRDNNEDSYLIIPQARVLALADGMGGAAAGEVASQHFVDMVRIAFS
CCEECCCCCCCEEEEECCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ELASPRKESVSERIQHVFERANARILEHIIQHPADTGMGCTADLLVFDGERYIIGHVGDS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEECCCC
RVYLLRDGRLQQLTKDHSLVQSQVDRGMLTPQEAKHHFRKNILLRAVGTDSAIACDIVQG
EEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEECCCCHHHHHHHHH
AVLGSDIFLLCSDGLTDMVGNADIEIVLASAEPLEQKVERLISAALEAGGKDNVTVILCE
HHCCCCEEEEECCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEEE
VEDA
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]