Click here to switch to the map view.

The map label for this gene is sucD [H]

Identifier: 82703116

GI number: 82703116

Start: 2291847

End: 2292725

Strand: Reverse

Name: sucD [H]

Synonym: Nmul_A1995

Alternate gene names: 82703116

Gene position: 2292725-2291847 (Counterclockwise)

Preceding gene: 82703117

Following gene: 82703115

Centisome position: 72.0

GC content: 55.29

Gene sequence:

>879_bases
ATGGCGATCCTGATCGACCGTAACACTCGTATCATGACGCAGGGGATTACCGGCAAGACCGGGCAATTCCACACGCGGAT
GTGTCGGGATTATGCTTATGGAAAAGAATGCTTTGTTGCCGGAGTCAATCCGAAGAAAGGGGGCGAGGATTTTGATGGCA
TCCCGATTTTCGGCACCGTAGAGGAAGCAAAGCAGGCAACAGGAGCCGCCGTTTCTGTAATCTATGTGCCGCCACCGTTT
GCCGCTGCCGCAATCGATGAAGCGGTGGATGCGGAACTGGATCTGGTAATCTGTATTACCGAAGGTATCCCTGTGCGCGA
TATGATACGTACCTGCCACAGGATGGAAGGAAAAAAAACGCGGCTGGTAGGACCGAATTGTCCCGGCATCATTACGCCCG
ACGAGATCAAGATTGGCATCATGCCCGGTTACATTCATCGAAAGGGACGCATCGGGGTGGTTTCCCGTTCCGGGACACTC
ACTTACGAAGCGGTGGCGCAATTGATGGAGCAGGAATTGGGTCAATCCACCTGCATCGGTATCGGCGGCGACCCGGTGAA
TGGCTTGAGGCATCGGGATGTGATGAAGCTGTTCAACGAAGATGATGAAACCGACGCTGTTTTAATGGTGGGGGAAATCG
GCGGTACCGACGAGGAGGATTGCGCTCGCTGGGTCAAGGAGAATATGCGTAAACCAGTGGTAGGATATATCGCAGGCTTG
ACAGCCCCTCCGGGCAGGCGCATGGGCCACGCCGGCGCCGTTATTTCGGGCGGTCGCGGAACCGCTCAGGAAAAGCTTGC
GGTCCTGGAAGAATGCGGAATCAAAGTCGCGCGAAATCCCGCTGAGATGGGCAAGGTTCTCAAGTCCGCATTGGGTTGA

Upstream 100 bases:

>100_bases
GATGCCGCGGAAAAGGCCGTTACCGCAGCCGCATCAGCCACCTCGGCCGCCATGCCGGCCACAGGGTCGTGAACAGAATC
GGCAAACGAGGGAAATCAGT

Downstream 100 bases:

>100_bases
ATAATGCTTATCCCTGAAACTGCTTTGAAGGAAAGCAGCATGATTTTCTCGCAATGAATTTTCTTTCGTTGATTTTCGCT
CTTCTGCTGGATCAGTGGCG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MAILIDRNTRIMTQGITGKTGQFHTRMCRDYAYGKECFVAGVNPKKGGEDFDGIPIFGTVEEAKQATGAAVSVIYVPPPF
AAAAIDEAVDAELDLVICITEGIPVRDMIRTCHRMEGKKTRLVGPNCPGIITPDEIKIGIMPGYIHRKGRIGVVSRSGTL
TYEAVAQLMEQELGQSTCIGIGGDPVNGLRHRDVMKLFNEDDETDAVLMVGEIGGTDEEDCARWVKENMRKPVVGYIAGL
TAPPGRRMGHAGAVISGGRGTAQEKLAVLEECGIKVARNPAEMGKVLKSALG

Sequences:

>Translated_292_residues
MAILIDRNTRIMTQGITGKTGQFHTRMCRDYAYGKECFVAGVNPKKGGEDFDGIPIFGTVEEAKQATGAAVSVIYVPPPF
AAAAIDEAVDAELDLVICITEGIPVRDMIRTCHRMEGKKTRLVGPNCPGIITPDEIKIGIMPGYIHRKGRIGVVSRSGTL
TYEAVAQLMEQELGQSTCIGIGGDPVNGLRHRDVMKLFNEDDETDAVLMVGEIGGTDEEDCARWVKENMRKPVVGYIAGL
TAPPGRRMGHAGAVISGGRGTAQEKLAVLEECGIKVARNPAEMGKVLKSALG
>Mature_291_residues
AILIDRNTRIMTQGITGKTGQFHTRMCRDYAYGKECFVAGVNPKKGGEDFDGIPIFGTVEEAKQATGAAVSVIYVPPPFA
AAAIDEAVDAELDLVICITEGIPVRDMIRTCHRMEGKKTRLVGPNCPGIITPDEIKIGIMPGYIHRKGRIGVVSRSGTLT
YEAVAQLMEQELGQSTCIGIGGDPVNGLRHRDVMKLFNEDDETDAVLMVGEIGGTDEEDCARWVKENMRKPVVGYIAGLT
APPGRRMGHAGAVISGGRGTAQEKLAVLEECGIKVARNPAEMGKVLKSALG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=290, Percent_Identity=55.5172413793103, Blast_Score=279, Evalue=2e-75,
Organism=Homo sapiens, GI38569423, Length=211, Percent_Identity=29.3838862559242, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI38569421, Length=211, Percent_Identity=29.3838862559242, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786949, Length=291, Percent_Identity=54.639175257732, Blast_Score=331, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=53.4246575342466, Blast_Score=300, Evalue=8e-82,
Organism=Caenorhabditis elegans, GI17553126, Length=294, Percent_Identity=51.0204081632653, Blast_Score=286, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI17557344, Length=209, Percent_Identity=27.7511961722488, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=212, Percent_Identity=27.8301886792453, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=45.578231292517, Blast_Score=257, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=50, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=53.8194444444444, Blast_Score=279, Evalue=1e-75,
Organism=Drosophila melanogaster, GI281363477, Length=213, Percent_Identity=28.6384976525822, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363475, Length=213, Percent_Identity=28.6384976525822, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363473, Length=213, Percent_Identity=28.6384976525822, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31269; Mature: 31137

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILIDRNTRIMTQGITGKTGQFHTRMCRDYAYGKECFVAGVNPKKGGEDFDGIPIFGTV
CEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEECH
EEAKQATGAAVSVIYVPPPFAAAAIDEAVDAELDLVICITEGIPVRDMIRTCHRMEGKKT
HHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCE
RLVGPNCPGIITPDEIKIGIMPGYIHRKGRIGVVSRSGTLTYEAVAQLMEQELGQSTCIG
EEECCCCCCCCCCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHHHHCCCCEEEE
IGGDPVNGLRHRDVMKLFNEDDETDAVLMVGEIGGTDEEDCARWVKENMRKPVVGYIAGL
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHCC
TAPPGRRMGHAGAVISGGRGTAQEKLAVLEECGIKVARNPAEMGKVLKSALG
CCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
AILIDRNTRIMTQGITGKTGQFHTRMCRDYAYGKECFVAGVNPKKGGEDFDGIPIFGTV
EEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEECH
EEAKQATGAAVSVIYVPPPFAAAAIDEAVDAELDLVICITEGIPVRDMIRTCHRMEGKKT
HHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCE
RLVGPNCPGIITPDEIKIGIMPGYIHRKGRIGVVSRSGTLTYEAVAQLMEQELGQSTCIG
EEECCCCCCCCCCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHHHHCCCCEEEE
IGGDPVNGLRHRDVMKLFNEDDETDAVLMVGEIGGTDEEDCARWVKENMRKPVVGYIAGL
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHCC
TAPPGRRMGHAGAVISGGRGTAQEKLAVLEECGIKVARNPAEMGKVLKSALG
CCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA