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The map label for this gene is dhaR [H]

Identifier: 82703088

GI number: 82703088

Start: 2262548

End: 2263156

Strand: Direct

Name: dhaR [H]

Synonym: Nmul_A1967

Alternate gene names: 82703088

Gene position: 2262548-2263156 (Clockwise)

Preceding gene: 82703084

Following gene: 82703089

Centisome position: 71.05

GC content: 49.59

Gene sequence:

>609_bases
ATGACGCGATCTGCAAAAAAAGAAGCGAGCAGGGATAATCTGTTGAATCAGGGTGTAAGCATGCTCATGCGTCAGGGCTA
CCACGGTACTGGTCTCCAGGAAATTCTGGATGCGGTAAATATTCCCAAAGGCTCTTTTTATAATTACTTCGACAGCAAGG
AGGATTTTGGCGCCAAGGTTATCCAACATTACGTCGATCCTTTTATCACCCAGCTGACCACTCATTTACAACGCTCCGAG
CCCGACGCACTGGGTGCAATACAGTGTTATTTTGATGAGCTTGTCGCGGAGCTGGAGAAAAACGATTTCAAGGGTGGCTG
CCTCCTTGGGAATCTAATGGGCGAGATAGGTGATACCAGTCCTCTTTGCCAGCAATCCCTCCAGACGGCTGTTACCCGGT
ATCGGGATTTGCTGCAATCTGGCTTGGTCAAGGCTCAGCAACAAGGCACGGTCAGAACAGACAAATCAGCGGTGGAGATG
GCCGATTTATTAATAAATGCCTGGCAGGGAGCTTTGCTGAGAGCGAAGATCGAAAAATCGCCCGCACCTGTCAAGCAATG
CTGTCAGGATCTGCTCGGAGATTTTTTCAGGCCTCCTGCATCTGGCTAA

Upstream 100 bases:

>100_bases
CTTTTTTCTGTATGACTGAATGAGGTTCGTTAATCTGCTTCAGCATGAACATAGCAAAGAACAGTTGACGAAAAAAGACA
ACCGGTCGTATTATTAATAC

Downstream 100 bases:

>100_bases
TATTTTTTTCTCTTTTATTAAGACGACCAGTCATATATTTATTAATCGAAACAAGAGGTATAAATGCCCAAATTCATCAT
TGAACGTGAGATTCCCGAAG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTRSAKKEASRDNLLNQGVSMLMRQGYHGTGLQEILDAVNIPKGSFYNYFDSKEDFGAKVIQHYVDPFITQLTTHLQRSE
PDALGAIQCYFDELVAELEKNDFKGGCLLGNLMGEIGDTSPLCQQSLQTAVTRYRDLLQSGLVKAQQQGTVRTDKSAVEM
ADLLINAWQGALLRAKIEKSPAPVKQCCQDLLGDFFRPPASG

Sequences:

>Translated_202_residues
MTRSAKKEASRDNLLNQGVSMLMRQGYHGTGLQEILDAVNIPKGSFYNYFDSKEDFGAKVIQHYVDPFITQLTTHLQRSE
PDALGAIQCYFDELVAELEKNDFKGGCLLGNLMGEIGDTSPLCQQSLQTAVTRYRDLLQSGLVKAQQQGTVRTDKSAVEM
ADLLINAWQGALLRAKIEKSPAPVKQCCQDLLGDFFRPPASG
>Mature_201_residues
TRSAKKEASRDNLLNQGVSMLMRQGYHGTGLQEILDAVNIPKGSFYNYFDSKEDFGAKVIQHYVDPFITQLTTHLQRSEP
DALGAIQCYFDELVAELEKNDFKGGCLLGNLMGEIGDTSPLCQQSLQTAVTRYRDLLQSGLVKAQQQGTVRTDKSAVEMA
DLLINAWQGALLRAKIEKSPAPVKQCCQDLLGDFFRPPASG

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=176, Percent_Identity=28.9772727272727, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22320; Mature: 22188

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSAKKEASRDNLLNQGVSMLMRQGYHGTGLQEILDAVNIPKGSFYNYFDSKEDFGAKV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHCCCCHHHHHHH
IQHYVDPFITQLTTHLQRSEPDALGAIQCYFDELVAELEKNDFKGGCLLGNLMGEIGDTS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
PLCQQSLQTAVTRYRDLLQSGLVKAQQQGTVRTDKSAVEMADLLINAWQGALLRAKIEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAPVKQCCQDLLGDFFRPPASG
CCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRSAKKEASRDNLLNQGVSMLMRQGYHGTGLQEILDAVNIPKGSFYNYFDSKEDFGAKV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHCCCCHHHHHHH
IQHYVDPFITQLTTHLQRSEPDALGAIQCYFDELVAELEKNDFKGGCLLGNLMGEIGDTS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
PLCQQSLQTAVTRYRDLLQSGLVKAQQQGTVRTDKSAVEMADLLINAWQGALLRAKIEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAPVKQCCQDLLGDFFRPPASG
CCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]