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The map label for this gene is mdtA [H]

Identifier: 82702962

GI number: 82702962

Start: 2122326

End: 2123558

Strand: Direct

Name: mdtA [H]

Synonym: Nmul_A1841

Alternate gene names: 82702962

Gene position: 2122326-2123558 (Clockwise)

Preceding gene: 82702961

Following gene: 82702963

Centisome position: 66.65

GC content: 59.12

Gene sequence:

>1233_bases
GTGCTGAAACAACTGGCAAGCAAGGGCATGCTCAAAATCATCATCCCCGTTCTTGTTGTGCTGGCCGGCATCAGTATTTC
GTGGGCGATTGCTGTTCACCGCCCGTCACTGAAATCCGAATTGCCGGATAGCGGAATACCAGCGGTACAGGTGATCGAGA
CAACTCCCCAAACGATCAAGCTGAATATTAGTTCCCAAGGTGTAGTCGTGCCCCGTACCGAGATTGATCTCGTCCCCGAG
GTAGCGGGTCAGATCGTTCGACTTCATCCCAGCCTGGCGGCCGGAGGTTTTTTTGAGGCGGGCGATATACTGATGATGAT
CGATCCCCGCGACTATGATCATGCGATCGCGGAGGCATACGCGCGCATCGCCGAGGCGGAGCGCCAGGTTGCGATGGAAG
AGGCGCAGGCGGAACAGGCACGCCAGGAATGGCAGGTTCTGGGGGAAGGAACACCCTCGCCTTTGACCATGCGGGAGCCG
CAACTGGCGGAGGCACGCGCAAAACTGAAGGCAGCGCAGGCCGACATGGTAAAAGCCCGCCTGCAGCGAGGCCGGTGCGA
GTGGCGCTCGCCATTTGCCGGGCGTGTGCGCAACATGCATATCGGTCTTGGTCAGTACGTTCAACCTGGAGAAAAGCTGG
CCCGCCTTTATGCGACCGATGTTGCCCAGATACGCCTGCCTTTGGCGACCGACCAATTCGCATACCTCGATCTTCTCCTC
GACCATAGGGACAACAAGGCAGAAAGGGGACCCAGGGTTGTCTTGAGCGGGGAATTTGCGGGCGCAACTCACCGATGGGA
GGGGCACGTTATCCGGACGGAGGGTGCGCTGGATGAGGAAACCGGGCTCCTCCACGCCGTTGCCGAAGTGCGGAATCCTT
ATAAGGTCAAGTCCGGCCAGCCTCCGCTCATACCCGGCTTGTTTGTAAAAGCGGAGATCGAAGGGCGGGAGCAGGCCGAT
GTCTTTGTATTGCCGCCCGGAGCCGTCAATGCTTCCCGGGAGGTGCTACTCGTCGATGCGGAAAACCGCCTGCATATCCG
CGGTGTAGAAATTTTGCGGCGTGAGCCCGATCGCATTCTCGCCAAAAGGGGGTTGAACGCGGGAGATAGGCTCGTCATCT
CGAGGATCGAGGTCCCCGTGGAGGGAATGAAGGTAAGCGCCGAGATTGTGGATCCGGGGCCGAAGCTCAAAAAGACCGGT
CTGGAGGCGCCAACACAGGATGGTGCGCTATGA

Upstream 100 bases:

>100_bases
GCACCCTCACTGCCCAGAGTGCGCATCTTTCCGTCAGGCGCCAGCTTCTGAGCAATCGAATCAATCTTTACCTGGCATTA
GGAGGCAGCATTTGCGAGGC

Downstream 100 bases:

>100_bases
GCGAAGCTTATATGCCCAGCTGTTCTTCGTTCCATTTGCTATGCCCGCCACTTTGCCAAGAGAAGAGTCTATCCGTGAGT
TTTTTTTAATGAAGGGCATC

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLKQLASKGMLKIIIPVLVVLAGISISWAIAVHRPSLKSELPDSGIPAVQVIETTPQTIKLNISSQGVVVPRTEIDLVPE
VAGQIVRLHPSLAAGGFFEAGDILMMIDPRDYDHAIAEAYARIAEAERQVAMEEAQAEQARQEWQVLGEGTPSPLTMREP
QLAEARAKLKAAQADMVKARLQRGRCEWRSPFAGRVRNMHIGLGQYVQPGEKLARLYATDVAQIRLPLATDQFAYLDLLL
DHRDNKAERGPRVVLSGEFAGATHRWEGHVIRTEGALDEETGLLHAVAEVRNPYKVKSGQPPLIPGLFVKAEIEGREQAD
VFVLPPGAVNASREVLLVDAENRLHIRGVEILRREPDRILAKRGLNAGDRLVISRIEVPVEGMKVSAEIVDPGPKLKKTG
LEAPTQDGAL

Sequences:

>Translated_410_residues
MLKQLASKGMLKIIIPVLVVLAGISISWAIAVHRPSLKSELPDSGIPAVQVIETTPQTIKLNISSQGVVVPRTEIDLVPE
VAGQIVRLHPSLAAGGFFEAGDILMMIDPRDYDHAIAEAYARIAEAERQVAMEEAQAEQARQEWQVLGEGTPSPLTMREP
QLAEARAKLKAAQADMVKARLQRGRCEWRSPFAGRVRNMHIGLGQYVQPGEKLARLYATDVAQIRLPLATDQFAYLDLLL
DHRDNKAERGPRVVLSGEFAGATHRWEGHVIRTEGALDEETGLLHAVAEVRNPYKVKSGQPPLIPGLFVKAEIEGREQAD
VFVLPPGAVNASREVLLVDAENRLHIRGVEILRREPDRILAKRGLNAGDRLVISRIEVPVEGMKVSAEIVDPGPKLKKTG
LEAPTQDGAL
>Mature_410_residues
MLKQLASKGMLKIIIPVLVVLAGISISWAIAVHRPSLKSELPDSGIPAVQVIETTPQTIKLNISSQGVVVPRTEIDLVPE
VAGQIVRLHPSLAAGGFFEAGDILMMIDPRDYDHAIAEAYARIAEAERQVAMEEAQAEQARQEWQVLGEGTPSPLTMREP
QLAEARAKLKAAQADMVKARLQRGRCEWRSPFAGRVRNMHIGLGQYVQPGEKLARLYATDVAQIRLPLATDQFAYLDLLL
DHRDNKAERGPRVVLSGEFAGATHRWEGHVIRTEGALDEETGLLHAVAEVRNPYKVKSGQPPLIPGLFVKAEIEGREQAD
VFVLPPGAVNASREVLLVDAENRLHIRGVEILRREPDRILAKRGLNAGDRLVISRIEVPVEGMKVSAEIVDPGPKLKKTG
LEAPTQDGAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=343, Percent_Identity=23.0320699708455, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789665, Length=374, Percent_Identity=22.7272727272727, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44876; Mature: 44876

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQLASKGMLKIIIPVLVVLAGISISWAIAVHRPSLKSELPDSGIPAVQVIETTPQTIK
CCHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCEEEEEECCCCEEE
LNISSQGVVVPRTEIDLVPEVAGQIVRLHPSLAAGGFFEAGDILMMIDPRDYDHAIAEAY
EEECCCCEEECCCCCCCCHHHHCCEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
ARIAEAERQVAMEEAQAEQARQEWQVLGEGTPSPLTMREPQLAEARAKLKAAQADMVKAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQRGRCEWRSPFAGRVRNMHIGLGQYVQPGEKLARLYATDVAQIRLPLATDQFAYLDLLL
HHCCCCCCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
DHRDNKAERGPRVVLSGEFAGATHRWEGHVIRTEGALDEETGLLHAVAEVRNPYKVKSGQ
HCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEECCCC
PPLIPGLFVKAEIEGREQADVFVLPPGAVNASREVLLVDAENRLHIRGVEILRREPDRIL
CCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEHHHHHCCHHHHH
AKRGLNAGDRLVISRIEVPVEGMKVSAEIVDPGPKLKKTGLEAPTQDGAL
HHCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLKQLASKGMLKIIIPVLVVLAGISISWAIAVHRPSLKSELPDSGIPAVQVIETTPQTIK
CCHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCEEEEEECCCCEEE
LNISSQGVVVPRTEIDLVPEVAGQIVRLHPSLAAGGFFEAGDILMMIDPRDYDHAIAEAY
EEECCCCEEECCCCCCCCHHHHCCEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
ARIAEAERQVAMEEAQAEQARQEWQVLGEGTPSPLTMREPQLAEARAKLKAAQADMVKAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQRGRCEWRSPFAGRVRNMHIGLGQYVQPGEKLARLYATDVAQIRLPLATDQFAYLDLLL
HHCCCCCCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
DHRDNKAERGPRVVLSGEFAGATHRWEGHVIRTEGALDEETGLLHAVAEVRNPYKVKSGQ
HCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEECCCC
PPLIPGLFVKAEIEGREQADVFVLPPGAVNASREVLLVDAENRLHIRGVEILRREPDRIL
CCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEHHHHHCCHHHHH
AKRGLNAGDRLVISRIEVPVEGMKVSAEIVDPGPKLKKTGLEAPTQDGAL
HHCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA