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The map label for this gene is czcC [H]

Identifier: 82702767

GI number: 82702767

Start: 1879350

End: 1880789

Strand: Reverse

Name: czcC [H]

Synonym: Nmul_A1641

Alternate gene names: 82702767

Gene position: 1880789-1879350 (Counterclockwise)

Preceding gene: 82702770

Following gene: 82702766

Centisome position: 59.07

GC content: 53.75

Gene sequence:

>1440_bases
ATGTATCCCGGAGTACTAGTTGATCGTGAGCAAGTTGATGTGCTTAATCTTCTGAGCAATGTGCTGCCTGCAGTACGAAT
TGCTCTGGGGATCATGCTGTTTTCGAGTATATCGGCAATGCTTCATGCAGCTTCTTTCACGGTTCAGGCAGAACCTGCAA
AAGAGGAATTTTCCATCACCGAACAGCAAGCGATCGCACTGTTCTATCAGCGCAACCTCGGCTTGATCGCAGCCAGCCTC
AACATCGATAACGCCAGGGCCCAGGAAATCATCGCCGCAGCGATTCCCAATCCGGTATTCAGTTTTACAGTTCACGAACT
GGCCCCAAAGGCATTCGCGCCGGAAAGCCGTCACCTGGCAGTCCCCGCGTATTTACCGCAGATTCAGCAGCTCATAGAAA
CGGCCGGAAAACGGCGTTTACGGATAGAAAGCAGCGAGCTGGCTACCGAGGCTGTGAACTTCGACGTGCAAGACGTTGCA
CGCGTGCTCACAAACACCGTGCGGCGCAGTTTTTACAACCTCCTGTTGGCCCAGAAGACGATCAAGGTTGCACGGGATAA
CCTCGAGCATTACCGGGAAATTCTGAGGGTAAACGAAATACGGCTCAAGGTAGGCGATGTTGCGGAGATGGATTTCGTTC
GTATCGAGGTTGAAAGCCTCAAGGTTCAAAGCGATCAGGATCAGGCAAGGGCTGCATTGAATCAGGCACGGGCCGACCTG
CTATTGCTGCTGGGCTGGCCTGAAAACAGCATAGAAATCAATGCCGCCGAAACCTGGCCTCAAGCAACGCCCGAGATTGC
GCTGGCGACGCAGGATCAATTGGTTGAACGCGCGCTGGAACGACGTCCGGATATGCGCGCTGCAAGGATACGCATCGCCC
AGGCGCGAAAAGTGCTCACACTCGCGCAACGGCAGGTTATTCCCGATGTGACAATAAGCGCGTTCTACGATCGGGATCAG
GGTAACCAGTTTCCGCGTACTGGCGGCGTGGGTATCAGCATACCAATCCCTTTGTTCTACCAGCAAAAAGGTGAAATTTC
CCAGGCTCGCGTAGGTTTGACTTCCAGCGAACTGGCATTAAGGCAGGCCGAGTATGACGTGCGCGCTGAAGTCATGAAGG
CCTCGGCAGCTTGGCAAAGCGCCGACGCCATAGCCCGGCGCTTTGAAACTTACGTGGTCAAAAAAATCGAGGCATTGCGC
AAGGCACAGGAAATTGCTTATCAAAAAGGGGCAGTGGGAGTGCTGGATCTGATCGATGCTGAGCGAAGCTATCGGACAAT
TATGCTGGATTATTATGCCGCGCTGGCAAACCGCAGCAAAGCCTGGGCTGATTTGCTGATGGCATATGGCGAGGAAACCG
GAAATCCGCGCTATCAATCCGGCAGCAACCAGGATGATTGGCGGTCCGCGCGTTCCCACCGGGTGAATTTCGGTAAATAA

Upstream 100 bases:

>100_bases
TGAACATGCTTGAAGGCGTGCGAAAGGCATTTTCCTGGTGCCGGAATTATCCGGACCGAAAGCCCCTCACCTTGCTTAGG
TAATACTCAGCGGTAAAGAT

Downstream 100 bases:

>100_bases
CCCTTTGCAGGCTGACGTGCCGTTTATCCCATCTTCCCGATCCTGACAGTCCGCATCCTGCATCATTCCTTCATGAAGCT
AATCCACAGCGCCTGAACGG

Product: Outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MYPGVLVDREQVDVLNLLSNVLPAVRIALGIMLFSSISAMLHAASFTVQAEPAKEEFSITEQQAIALFYQRNLGLIAASL
NIDNARAQEIIAAAIPNPVFSFTVHELAPKAFAPESRHLAVPAYLPQIQQLIETAGKRRLRIESSELATEAVNFDVQDVA
RVLTNTVRRSFYNLLLAQKTIKVARDNLEHYREILRVNEIRLKVGDVAEMDFVRIEVESLKVQSDQDQARAALNQARADL
LLLLGWPENSIEINAAETWPQATPEIALATQDQLVERALERRPDMRAARIRIAQARKVLTLAQRQVIPDVTISAFYDRDQ
GNQFPRTGGVGISIPIPLFYQQKGEISQARVGLTSSELALRQAEYDVRAEVMKASAAWQSADAIARRFETYVVKKIEALR
KAQEIAYQKGAVGVLDLIDAERSYRTIMLDYYAALANRSKAWADLLMAYGEETGNPRYQSGSNQDDWRSARSHRVNFGK

Sequences:

>Translated_479_residues
MYPGVLVDREQVDVLNLLSNVLPAVRIALGIMLFSSISAMLHAASFTVQAEPAKEEFSITEQQAIALFYQRNLGLIAASL
NIDNARAQEIIAAAIPNPVFSFTVHELAPKAFAPESRHLAVPAYLPQIQQLIETAGKRRLRIESSELATEAVNFDVQDVA
RVLTNTVRRSFYNLLLAQKTIKVARDNLEHYREILRVNEIRLKVGDVAEMDFVRIEVESLKVQSDQDQARAALNQARADL
LLLLGWPENSIEINAAETWPQATPEIALATQDQLVERALERRPDMRAARIRIAQARKVLTLAQRQVIPDVTISAFYDRDQ
GNQFPRTGGVGISIPIPLFYQQKGEISQARVGLTSSELALRQAEYDVRAEVMKASAAWQSADAIARRFETYVVKKIEALR
KAQEIAYQKGAVGVLDLIDAERSYRTIMLDYYAALANRSKAWADLLMAYGEETGNPRYQSGSNQDDWRSARSHRVNFGK
>Mature_479_residues
MYPGVLVDREQVDVLNLLSNVLPAVRIALGIMLFSSISAMLHAASFTVQAEPAKEEFSITEQQAIALFYQRNLGLIAASL
NIDNARAQEIIAAAIPNPVFSFTVHELAPKAFAPESRHLAVPAYLPQIQQLIETAGKRRLRIESSELATEAVNFDVQDVA
RVLTNTVRRSFYNLLLAQKTIKVARDNLEHYREILRVNEIRLKVGDVAEMDFVRIEVESLKVQSDQDQARAALNQARADL
LLLLGWPENSIEINAAETWPQATPEIALATQDQLVERALERRPDMRAARIRIAQARKVLTLAQRQVIPDVTISAFYDRDQ
GNQFPRTGGVGISIPIPLFYQQKGEISQARVGLTSSELALRQAEYDVRAEVMKASAAWQSADAIARRFETYVVKKIEALR
KAQEIAYQKGAVGVLDLIDAERSYRTIMLDYYAALANRSKAWADLLMAYGEETGNPRYQSGSNQDDWRSARSHRVNFGK

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53646; Mature: 53646

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPGVLVDREQVDVLNLLSNVLPAVRIALGIMLFSSISAMLHAASFTVQAEPAKEEFSIT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHH
EQQAIALFYQRNLGLIAASLNIDNARAQEIIAAAIPNPVFSFTVHELAPKAFAPESRHLA
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEE
VPAYLPQIQQLIETAGKRRLRIESSELATEAVNFDVQDVARVLTNTVRRSFYNLLLAQKT
CHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IKVARDNLEHYREILRVNEIRLKVGDVAEMDFVRIEVESLKVQSDQDQARAALNQARADL
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEEHHEECCCHHHHHHHHHHHCCCE
LLLLGWPENSIEINAAETWPQATPEIALATQDQLVERALERRPDMRAARIRIAQARKVLT
EEEEECCCCCEEEEECCCCCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LAQRQVIPDVTISAFYDRDQGNQFPRTGGVGISIPIPLFYQQKGEISQARVGLTSSELAL
HHHHHHCCCCCHHHEEECCCCCCCCCCCCCEEEECCCEEECCCCCHHHHHCCCCHHHHHH
RQAEYDVRAEVMKASAAWQSADAIARRFETYVVKKIEALRKAQEIAYQKGAVGVLDLIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
ERSYRTIMLDYYAALANRSKAWADLLMAYGEETGNPRYQSGSNQDDWRSARSHRVNFGK
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYPGVLVDREQVDVLNLLSNVLPAVRIALGIMLFSSISAMLHAASFTVQAEPAKEEFSIT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHH
EQQAIALFYQRNLGLIAASLNIDNARAQEIIAAAIPNPVFSFTVHELAPKAFAPESRHLA
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEE
VPAYLPQIQQLIETAGKRRLRIESSELATEAVNFDVQDVARVLTNTVRRSFYNLLLAQKT
CHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IKVARDNLEHYREILRVNEIRLKVGDVAEMDFVRIEVESLKVQSDQDQARAALNQARADL
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEEHHEECCCHHHHHHHHHHHCCCE
LLLLGWPENSIEINAAETWPQATPEIALATQDQLVERALERRPDMRAARIRIAQARKVLT
EEEEECCCCCEEEEECCCCCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LAQRQVIPDVTISAFYDRDQGNQFPRTGGVGISIPIPLFYQQKGEISQARVGLTSSELAL
HHHHHHCCCCCHHHEEECCCCCCCCCCCCCEEEECCCEEECCCCCHHHHHCCCCHHHHHH
RQAEYDVRAEVMKASAAWQSADAIARRFETYVVKKIEALRKAQEIAYQKGAVGVLDLIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
ERSYRTIMLDYYAALANRSKAWADLLMAYGEETGNPRYQSGSNQDDWRSARSHRVNFGK
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]