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The map label for this gene is czcB [H]

Identifier: 82702766

GI number: 82702766

Start: 1878083

End: 1879237

Strand: Reverse

Name: czcB [H]

Synonym: Nmul_A1640

Alternate gene names: 82702766

Gene position: 1879237-1878083 (Counterclockwise)

Preceding gene: 82702767

Following gene: 82702765

Centisome position: 59.02

GC content: 57.75

Gene sequence:

>1155_bases
ATGAAGTTACACCTTGTTATTCAGCTTGCGACAGGATTGCTGTGCCTGTCCCTGCTGGCCTGCCAGCAGCAAAACAACAG
CGAACCCCAACACACGGCTGTTCTGCCGCCTGCAGACGAAGTGATATTGCGGCCGGAATCGCCCAAGCGTCAGTATATCG
GGGAGGCCGTTATCGAACTCGTTCAGCGGCCATTGATGGATCCTGTCACGGGCAAGATTACCTATGACGAAATCCGCACG
GCGCGTGTCTCCTCGCCGATTGCCGGACGCGTAATCGGCGACATTGCCCCCCTGGGGGCACCGGTTCGCAAAGGCGACAC
ACTGGCGGTGCTGGATAGTCCGGACCTTGGAGAAGCGCAATCCGCTTACGCGGCCGCCGTGGCCGATCTGAATCTCGCCG
AGAGGAATTTTCAGCGGATACAGGAGTTGTATGAGAACGGCATTGCGCCGCGCAAGGAGCACGAGCAGGCCGAAGATAAT
CTGACACGCACGCGCAGCGAGGCCGAACGGGCCAGGCTCAAGCTTGCAAACCTGGGGGCGCGTCCGGGACGAATGGATAA
CCGCTTTTCCCTGCGCGCATCCATTCCGGGAACGGTTACGGAACGCAATATCAATCCTGGGATGGAAGTCAGGCCGGACC
TTGTTGCACCGCTGTTTGTCATTTCCGACCTGCAGCAGTTATGGGTGCAGATGGATATTTTCGAGAAGGATATCGGCCAG
ATTCACATAGGCACGAAGATTGTGCTGAAAGTGCCTGCCTATTCCGGCCGGAATTTTAATGCGACTGTCAGCTACATCAG
TCAGGTGGTGGACGAAAGCTCGCGCACGGTAAAAGTGCGCTGCATTCTGCCTAATGAGGATGGCCGCCTGCTGCCTTCCA
TGTTTGCCGCCATCGATGTCCAAAGCGATGCGGGCGATCTTGCAATTGTCGTGCCATTAACGGCACTATTTACCGAGAAC
GAGTCCGACTGGGTCTATGTGAACATCGGAGATTACCGCTACCGCAGGCGTCCGGTTAAAGTAGGCCTGCGTCTCAAGGA
CCGCGCCGTAATTCTCGAGGGCCTGAAGCCGGGTGAGCGCCTGGTCGTGCATGGCGCCCTGCTGTTGCGCACCGAGCAGG
ACACCGAGCATCAAACCGGGGAAAGCGCACCATGA

Upstream 100 bases:

>100_bases
TGACGTGCCGTTTATCCCATCTTCCCGATCCTGACAGTCCGCATCCTGCATCATTCCTTCATGAAGCTAATCCACAGCGC
CTGAACGGCTTGAATATGAA

Downstream 100 bases:

>100_bases
CTTATAAAATCATTGCGTTCTGCCTGCAGCAGCGCCTGCTGGTCCTTATTGCATCAGGATTGCTGGCGGTCATCGGCCTC
TTTTCGTTCGAGCGTCTGCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKLHLVIQLATGLLCLSLLACQQQNNSEPQHTAVLPPADEVILRPESPKRQYIGEAVIELVQRPLMDPVTGKITYDEIRT
ARVSSPIAGRVIGDIAPLGAPVRKGDTLAVLDSPDLGEAQSAYAAAVADLNLAERNFQRIQELYENGIAPRKEHEQAEDN
LTRTRSEAERARLKLANLGARPGRMDNRFSLRASIPGTVTERNINPGMEVRPDLVAPLFVISDLQQLWVQMDIFEKDIGQ
IHIGTKIVLKVPAYSGRNFNATVSYISQVVDESSRTVKVRCILPNEDGRLLPSMFAAIDVQSDAGDLAIVVPLTALFTEN
ESDWVYVNIGDYRYRRRPVKVGLRLKDRAVILEGLKPGERLVVHGALLLRTEQDTEHQTGESAP

Sequences:

>Translated_384_residues
MKLHLVIQLATGLLCLSLLACQQQNNSEPQHTAVLPPADEVILRPESPKRQYIGEAVIELVQRPLMDPVTGKITYDEIRT
ARVSSPIAGRVIGDIAPLGAPVRKGDTLAVLDSPDLGEAQSAYAAAVADLNLAERNFQRIQELYENGIAPRKEHEQAEDN
LTRTRSEAERARLKLANLGARPGRMDNRFSLRASIPGTVTERNINPGMEVRPDLVAPLFVISDLQQLWVQMDIFEKDIGQ
IHIGTKIVLKVPAYSGRNFNATVSYISQVVDESSRTVKVRCILPNEDGRLLPSMFAAIDVQSDAGDLAIVVPLTALFTEN
ESDWVYVNIGDYRYRRRPVKVGLRLKDRAVILEGLKPGERLVVHGALLLRTEQDTEHQTGESAP
>Mature_384_residues
MKLHLVIQLATGLLCLSLLACQQQNNSEPQHTAVLPPADEVILRPESPKRQYIGEAVIELVQRPLMDPVTGKITYDEIRT
ARVSSPIAGRVIGDIAPLGAPVRKGDTLAVLDSPDLGEAQSAYAAAVADLNLAERNFQRIQELYENGIAPRKEHEQAEDN
LTRTRSEAERARLKLANLGARPGRMDNRFSLRASIPGTVTERNINPGMEVRPDLVAPLFVISDLQQLWVQMDIFEKDIGQ
IHIGTKIVLKVPAYSGRNFNATVSYISQVVDESSRTVKVRCILPNEDGRLLPSMFAAIDVQSDAGDLAIVVPLTALFTEN
ESDWVYVNIGDYRYRRRPVKVGLRLKDRAVILEGLKPGERLVVHGALLLRTEQDTEHQTGESAP

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=309, Percent_Identity=25.5663430420712, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786787, Length=308, Percent_Identity=26.6233766233766, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42468; Mature: 42468

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHLVIQLATGLLCLSLLACQQQNNSEPQHTAVLPPADEVILRPESPKRQYIGEAVIEL
CEEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHH
VQRPLMDPVTGKITYDEIRTARVSSPIAGRVIGDIAPLGAPVRKGDTLAVLDSPDLGEAQ
HHHHCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHH
SAYAAAVADLNLAERNFQRIQELYENGIAPRKEHEQAEDNLTRTRSEAERARLKLANLGA
HHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RPGRMDNRFSLRASIPGTVTERNINPGMEVRPDLVAPLFVISDLQQLWVQMDIFEKDIGQ
CCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IHIGTKIVLKVPAYSGRNFNATVSYISQVVDESSRTVKVRCILPNEDGRLLPSMFAAIDV
EEECEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHEEE
QSDAGDLAIVVPLTALFTENESDWVYVNIGDYRYRRRPVKVGLRLKDRAVILEGLKPGER
CCCCCCEEEEEEEEEEEECCCCCEEEEEECCCHHHCCCEEECEEEECCEEEEECCCCCCE
LVVHGALLLRTEQDTEHQTGESAP
EEEEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKLHLVIQLATGLLCLSLLACQQQNNSEPQHTAVLPPADEVILRPESPKRQYIGEAVIEL
CEEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHH
VQRPLMDPVTGKITYDEIRTARVSSPIAGRVIGDIAPLGAPVRKGDTLAVLDSPDLGEAQ
HHHHCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHH
SAYAAAVADLNLAERNFQRIQELYENGIAPRKEHEQAEDNLTRTRSEAERARLKLANLGA
HHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RPGRMDNRFSLRASIPGTVTERNINPGMEVRPDLVAPLFVISDLQQLWVQMDIFEKDIGQ
CCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IHIGTKIVLKVPAYSGRNFNATVSYISQVVDESSRTVKVRCILPNEDGRLLPSMFAAIDV
EEECEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHEEE
QSDAGDLAIVVPLTALFTENESDWVYVNIGDYRYRRRPVKVGLRLKDRAVILEGLKPGER
CCCCCCEEEEEEEEEEEECCCCCEEEEEECCCHHHCCCEEECEEEECCEEEEECCCCCCE
LVVHGALLLRTEQDTEHQTGESAP
EEEEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]