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The map label for this gene is putA [H]

Identifier: 82702675

GI number: 82702675

Start: 1768095

End: 1771760

Strand: Reverse

Name: putA [H]

Synonym: Nmul_A1546

Alternate gene names: 82702675

Gene position: 1771760-1768095 (Counterclockwise)

Preceding gene: 82702679

Following gene: 82702674

Centisome position: 55.64

GC content: 57.72

Gene sequence:

>3666_bases
GTGGGAAAAACGGCCGCCTGTCCTCGCTTCTTGCGCTCTGCAATTACCCACGCGTATCGGCACAATGAGACTGAAAGCGT
GAATGGCTTGTTGAGGCAGATCGATTGGCCGCCATGCAGTCGTGCCCGAGCTGAGGAACTCGCCCGTAAGCTGGTGACTT
CGATGCGAGGCAAATACAGTCATAGGGGCGGCGTGGATGCCTTGATGCACGAATTTTCCCTGTCGAGTCAAGAGGGTGTA
GCTCTGATGTGCCTGGCCGAGGCGCTGCTGCGCATCCCGGATCGGGAGACTGCAGATCGTCTCATACGGGACAAGATCAG
CAAGGGTGACTGGCGCGTACATGTGGGACACAGCCCTTCGCTTTTCGTAAATGCGGCGGCCTGGGGCCTTCTGATCTCTC
GCAAGCTGGTTTCGACCCACAGAGAAGATGGACTGTCAGCCGCATTATCCGGATTGATGGAAAAGGGGGGCGAGCCGCTG
ATTCGAAAAGGAATGGATCTGGCAATGCGTATGCTGGGCCACCAGTTCGTGATTGGCGAAACCATCGAGGAAGCGCTGGA
GCGTAGCCGTGAGCGCGAGATGCGGGGATATCGTTATTCATACGATATGCTGGGGGAAGCGGCAATAACGGAGGCTGACG
CCCAGCGCTACTGGACTTCCTACGCCTCGGCTATCCATGCTATCGGCAAGTCGCGCGGCAAGGGTGGTATTAAGAGCGGT
ATTTATAGGGGACCAGGAATTTCAGTAAAGCTTTCCGCACTGCATCCCCGCTATGTGCGCTCCCAGCGCGAGCGAGTGAT
GTCTGAGCTGTTGCCACGTCTTAAATCACTGCTGCTGCTTGCCAAGCACTATGACATGGGCTTCAACATGGATGCGGAGG
AAGCCGATCGGCTCGATCTCTCGCTCGATCTCCTGGAAGCGCTCGTGTTCGACCCGGATCTTGCGGGTTGGGATGGCATC
GGCTTTGTCGTCCAGGCCTATCAGAAGCGATGCCCGTTCGTTGTCGATTGGCTCATCGATCTTGCGCGGCGCAGCGGTCA
TCGCCTCATGGTTCGGCTTGTGAAGGGCGCATACTGGGATGGGGAAATCAAGCGTGCACAGGTAGAGGGGCTGGATGGCT
ATCCCGTTTACACGCGCAAGATTCACACCGACATATGCTATATGGTTTGCGCGCAGAAACTTCTTCGCGCTGCGGAAGCG
GTCTTTCCCCAGTTCGCCACTCATAATGCACACACATTGTCAGCCGTATACCAAATAGCACAGGATGCGGATATCGAAGA
TTACGAGTTCCAGTACCTGCACGGGATGGGCGAGACGCTGTATGACCAGGTCGAACTTCTGAAAGAGGACCGGTTCGTAA
AGCCGTGCCGCATTTATGCGCCTGTAGGCAGCTATGAGACGCTGCTTGCTTACCTCGCGCGCCGCCTGCTTGAGAATGGC
GCAAATTCGTCATTCGTCAACCGCATTCTCGACGATGATATCGTTGTAGAAGAGCTGGTTGCGGATCCAGTCAGTCAGAT
CGAACAGGAGGGGGTGCATCCTCATCCGGCGATTCCCTTACCCGGCGATTTGTACGGCCACAAGCGCAGGAATTCCGCAG
GCCTTGATTTCAGCGACGAGCAAGCGCTGGCTGCGCTGTCTGCTGAATTGACTGAAATGGAAAGGCGTGAATGGAGAGCC
AGGCCTGTGCTGGCAGCGGGGGGGAATGCCGGAAATGCGGGTTCACGGGTTCTCAATCCTGCTGATCGCAATGATTCCGC
CGGCACGGTGGTAGAGGCGACCGAGCATGATGTCGAAGATGCAATCGCTGTCGCGCACGCGTTCGTAGCCGAATGGCAAA
GTGTATCGCATGAAGCCAGAGCCGCGATGCTTGAGCGGGCAGCGGATGCACTGGAAGCGCACCGCACGGAACTGATGGGA
CTTGCGATACGCGAAGCCGGCAAGTCATTACCGGATGCAGTCGCGGAAGTGCGTGAAGCGGTTGATTTTTGCCGTTATTA
CGGGCAACAGATACGCGACTGGCCCAACATGAGTCCGTCTTCAGCGCTCGGCCCTGTCGTCTGTATCAGCCCCTGGAATT
TCCCGCTGGCAATATTCATTGGCCAGGTAAGTGCCGCACTTGCTGCCGGCAATCCCGTACTCGCGAAGCCAGCCGAGCAG
ACGCCCTTGATTGCCGCCGTTGCCGTCAGGCTGCTGCACGCGGCAGGTATTCCACGGGCAGCATTGCAGCTTTTGCCGGG
ACAGGGCGAGAGGGTTGGAGAGCAGCTTGTCAAAGATGTCCGGGTGCGTGGAGTTATTTTCACTGGCTCTACCGAAGTGG
CGCAACTCATTTGCCGTACACTCGCCCTTCGTGCGCAGAAAAGCGAAATCCTCTTCATCGCCGAGACCGGAGGCCAGAAT
GCGATGATCGTCGATTCATCCGCTCGTATCGAGCAGGTGGTGCAGGATGCGCTGACGTCGGCGTTCGATAGCGCGGGACA
GCGTTGCTCGGCGCTGCGGGTATTGTGCTTGCAGGAAGATATCGCTGAACAGGTGCTGGAGGTTCTGAGAGGGGCAATGG
GAGAACTCACGGTGGGGGATCCCCGGGAGCTCGCTACCGATGTCGGCCCGGTAATTGATGCAGATGCTCAGCACGCGCTG
CTCGATCATATCGAAAAAATGCGCGCGGCAGGTCATACCGTGTTCCAAGCGGCACTACCGTCGGTTTGCGCAAACGGCAC
TTTCGTTGCACCAACCTTGATCGAGATTGATCATATAGATGAGCTAGAGCGTGAGGTGTTCGGGCCGGTGCTGCATGTCG
TGCGTTTTGCCCGCGAACGGGTGGACGAGCTTGTTGGCCAGATCAACGCGACTGGCTACGGTCTGACGCATGGCATTCAC
AGTCGGGTCGATGAGACCATCGATTTCATTACCAAGCGTGTGCATGCCGGCAACATCTATGTCAATCGCAATATGATCGG
GGCCGTGGTCGGCGTGCAACCCTTTGGCGGGGAGGGCAAATCGGGTACCGGGCCCAAGGCCGGAGGGCCGCTCTACCTGC
ATCGGCTGATGCCTCAGACGCCCCTCTTGCTGGCGGATAACGGCGGACTGCGGGTGAACAGTCCACCAGTTGAGTTGCAA
GTGCTTGCCGCGTGGGCTCGGCAAGCGGGACGGGACGTACTCGCCTCGTTGTGCGAGGATTACGCGATGCGCACACCCTT
TGCATTCAGCATTCCATTACCGGGACCGACAGGCGAGAGCAATACATTAAAATTCGCCCCACGGAGAGCGGTAGCTTGTA
TTGCCGTAGACGAAGATGCATTGCTTGAGCAGATGGCGGCGGCACTGGCAACCGGCAACCAGATTATCTTGGCTGATAAC
CCGCCTTTGCGCGCGTTGCTGGATAAGCTGCCGTCGCAAGTGCGGAATCGATTGCGCATCGAGCGGGAGTGGATCCACGC
ACCCGTTTCTGCGGTGCTCTATTCAGGCCCTGAAGATGAGGCGTACCGGCTCCGAAACGAGCTGGCGGGACGCGAAGGCG
CTCTAGTCGCATTCATTACAGCCTCCGGCACTGACTTCCCTTTATATCGGCTGACGGCTGAGCGGGTGGTTAGCGTGAAT
ACCACTGCTGCTGGCGGCAATCCTGGCTTGATGGGACTTGATTTCAATGGATCATCCACCCATTAG

Upstream 100 bases:

>100_bases
AAAGCGATTCGAAAATCTAGAACGTTCTGCACTGCTTTTATAACTTTTTGCCGTAATCAGCTTCCCATCAGGAATCATCG
CTTCGCTCATAAGGAAAAAC

Downstream 100 bases:

>100_bases
CCGGCCATAAGGCAAGAATCTAGGTTTGGATTCAAGCTTCTCAAGATGAACTGAGGCGCTATATTTAAAACAGATCTTGA
TATTCATATATAAAGCGAGG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1221; Mature: 1220

Protein sequence:

>1221_residues
MGKTAACPRFLRSAITHAYRHNETESVNGLLRQIDWPPCSRARAEELARKLVTSMRGKYSHRGGVDALMHEFSLSSQEGV
ALMCLAEALLRIPDRETADRLIRDKISKGDWRVHVGHSPSLFVNAAAWGLLISRKLVSTHREDGLSAALSGLMEKGGEPL
IRKGMDLAMRMLGHQFVIGETIEEALERSREREMRGYRYSYDMLGEAAITEADAQRYWTSYASAIHAIGKSRGKGGIKSG
IYRGPGISVKLSALHPRYVRSQRERVMSELLPRLKSLLLLAKHYDMGFNMDAEEADRLDLSLDLLEALVFDPDLAGWDGI
GFVVQAYQKRCPFVVDWLIDLARRSGHRLMVRLVKGAYWDGEIKRAQVEGLDGYPVYTRKIHTDICYMVCAQKLLRAAEA
VFPQFATHNAHTLSAVYQIAQDADIEDYEFQYLHGMGETLYDQVELLKEDRFVKPCRIYAPVGSYETLLAYLARRLLENG
ANSSFVNRILDDDIVVEELVADPVSQIEQEGVHPHPAIPLPGDLYGHKRRNSAGLDFSDEQALAALSAELTEMERREWRA
RPVLAAGGNAGNAGSRVLNPADRNDSAGTVVEATEHDVEDAIAVAHAFVAEWQSVSHEARAAMLERAADALEAHRTELMG
LAIREAGKSLPDAVAEVREAVDFCRYYGQQIRDWPNMSPSSALGPVVCISPWNFPLAIFIGQVSAALAAGNPVLAKPAEQ
TPLIAAVAVRLLHAAGIPRAALQLLPGQGERVGEQLVKDVRVRGVIFTGSTEVAQLICRTLALRAQKSEILFIAETGGQN
AMIVDSSARIEQVVQDALTSAFDSAGQRCSALRVLCLQEDIAEQVLEVLRGAMGELTVGDPRELATDVGPVIDADAQHAL
LDHIEKMRAAGHTVFQAALPSVCANGTFVAPTLIEIDHIDELEREVFGPVLHVVRFARERVDELVGQINATGYGLTHGIH
SRVDETIDFITKRVHAGNIYVNRNMIGAVVGVQPFGGEGKSGTGPKAGGPLYLHRLMPQTPLLLADNGGLRVNSPPVELQ
VLAAWARQAGRDVLASLCEDYAMRTPFAFSIPLPGPTGESNTLKFAPRRAVACIAVDEDALLEQMAAALATGNQIILADN
PPLRALLDKLPSQVRNRLRIEREWIHAPVSAVLYSGPEDEAYRLRNELAGREGALVAFITASGTDFPLYRLTAERVVSVN
TTAAGGNPGLMGLDFNGSSTH

Sequences:

>Translated_1221_residues
MGKTAACPRFLRSAITHAYRHNETESVNGLLRQIDWPPCSRARAEELARKLVTSMRGKYSHRGGVDALMHEFSLSSQEGV
ALMCLAEALLRIPDRETADRLIRDKISKGDWRVHVGHSPSLFVNAAAWGLLISRKLVSTHREDGLSAALSGLMEKGGEPL
IRKGMDLAMRMLGHQFVIGETIEEALERSREREMRGYRYSYDMLGEAAITEADAQRYWTSYASAIHAIGKSRGKGGIKSG
IYRGPGISVKLSALHPRYVRSQRERVMSELLPRLKSLLLLAKHYDMGFNMDAEEADRLDLSLDLLEALVFDPDLAGWDGI
GFVVQAYQKRCPFVVDWLIDLARRSGHRLMVRLVKGAYWDGEIKRAQVEGLDGYPVYTRKIHTDICYMVCAQKLLRAAEA
VFPQFATHNAHTLSAVYQIAQDADIEDYEFQYLHGMGETLYDQVELLKEDRFVKPCRIYAPVGSYETLLAYLARRLLENG
ANSSFVNRILDDDIVVEELVADPVSQIEQEGVHPHPAIPLPGDLYGHKRRNSAGLDFSDEQALAALSAELTEMERREWRA
RPVLAAGGNAGNAGSRVLNPADRNDSAGTVVEATEHDVEDAIAVAHAFVAEWQSVSHEARAAMLERAADALEAHRTELMG
LAIREAGKSLPDAVAEVREAVDFCRYYGQQIRDWPNMSPSSALGPVVCISPWNFPLAIFIGQVSAALAAGNPVLAKPAEQ
TPLIAAVAVRLLHAAGIPRAALQLLPGQGERVGEQLVKDVRVRGVIFTGSTEVAQLICRTLALRAQKSEILFIAETGGQN
AMIVDSSARIEQVVQDALTSAFDSAGQRCSALRVLCLQEDIAEQVLEVLRGAMGELTVGDPRELATDVGPVIDADAQHAL
LDHIEKMRAAGHTVFQAALPSVCANGTFVAPTLIEIDHIDELEREVFGPVLHVVRFARERVDELVGQINATGYGLTHGIH
SRVDETIDFITKRVHAGNIYVNRNMIGAVVGVQPFGGEGKSGTGPKAGGPLYLHRLMPQTPLLLADNGGLRVNSPPVELQ
VLAAWARQAGRDVLASLCEDYAMRTPFAFSIPLPGPTGESNTLKFAPRRAVACIAVDEDALLEQMAAALATGNQIILADN
PPLRALLDKLPSQVRNRLRIEREWIHAPVSAVLYSGPEDEAYRLRNELAGREGALVAFITASGTDFPLYRLTAERVVSVN
TTAAGGNPGLMGLDFNGSSTH
>Mature_1220_residues
GKTAACPRFLRSAITHAYRHNETESVNGLLRQIDWPPCSRARAEELARKLVTSMRGKYSHRGGVDALMHEFSLSSQEGVA
LMCLAEALLRIPDRETADRLIRDKISKGDWRVHVGHSPSLFVNAAAWGLLISRKLVSTHREDGLSAALSGLMEKGGEPLI
RKGMDLAMRMLGHQFVIGETIEEALERSREREMRGYRYSYDMLGEAAITEADAQRYWTSYASAIHAIGKSRGKGGIKSGI
YRGPGISVKLSALHPRYVRSQRERVMSELLPRLKSLLLLAKHYDMGFNMDAEEADRLDLSLDLLEALVFDPDLAGWDGIG
FVVQAYQKRCPFVVDWLIDLARRSGHRLMVRLVKGAYWDGEIKRAQVEGLDGYPVYTRKIHTDICYMVCAQKLLRAAEAV
FPQFATHNAHTLSAVYQIAQDADIEDYEFQYLHGMGETLYDQVELLKEDRFVKPCRIYAPVGSYETLLAYLARRLLENGA
NSSFVNRILDDDIVVEELVADPVSQIEQEGVHPHPAIPLPGDLYGHKRRNSAGLDFSDEQALAALSAELTEMERREWRAR
PVLAAGGNAGNAGSRVLNPADRNDSAGTVVEATEHDVEDAIAVAHAFVAEWQSVSHEARAAMLERAADALEAHRTELMGL
AIREAGKSLPDAVAEVREAVDFCRYYGQQIRDWPNMSPSSALGPVVCISPWNFPLAIFIGQVSAALAAGNPVLAKPAEQT
PLIAAVAVRLLHAAGIPRAALQLLPGQGERVGEQLVKDVRVRGVIFTGSTEVAQLICRTLALRAQKSEILFIAETGGQNA
MIVDSSARIEQVVQDALTSAFDSAGQRCSALRVLCLQEDIAEQVLEVLRGAMGELTVGDPRELATDVGPVIDADAQHALL
DHIEKMRAAGHTVFQAALPSVCANGTFVAPTLIEIDHIDELEREVFGPVLHVVRFARERVDELVGQINATGYGLTHGIHS
RVDETIDFITKRVHAGNIYVNRNMIGAVVGVQPFGGEGKSGTGPKAGGPLYLHRLMPQTPLLLADNGGLRVNSPPVELQV
LAAWARQAGRDVLASLCEDYAMRTPFAFSIPLPGPTGESNTLKFAPRRAVACIAVDEDALLEQMAAALATGNQIILADNP
PLRALLDKLPSQVRNRLRIEREWIHAPVSAVLYSGPEDEAYRLRNELAGREGALVAFITASGTDFPLYRLTAERVVSVNT
TAAGGNPGLMGLDFNGSSTH

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=460, Percent_Identity=30.4347826086957, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI25777734, Length=460, Percent_Identity=30.4347826086957, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI21614513, Length=420, Percent_Identity=30.7142857142857, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI238859541, Length=460, Percent_Identity=30.4347826086957, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI21361176, Length=450, Percent_Identity=30.4444444444444, Blast_Score=171, Evalue=5e-42,
Organism=Homo sapiens, GI153266822, Length=449, Percent_Identity=28.2850779510022, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI25777732, Length=449, Percent_Identity=29.3986636971047, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI25777730, Length=452, Percent_Identity=29.646017699115, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI25777724, Length=449, Percent_Identity=28.0623608017817, Blast_Score=165, Evalue=3e-40,
Organism=Homo sapiens, GI238814322, Length=417, Percent_Identity=27.0983213429257, Blast_Score=162, Evalue=3e-39,
Organism=Homo sapiens, GI25777728, Length=403, Percent_Identity=28.5359801488834, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI12007648, Length=437, Percent_Identity=27.4599542334096, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI310128093, Length=451, Percent_Identity=29.7117516629712, Blast_Score=144, Evalue=5e-34,
Organism=Homo sapiens, GI310128103, Length=451, Percent_Identity=29.490022172949, Blast_Score=143, Evalue=8e-34,
Organism=Homo sapiens, GI188035924, Length=451, Percent_Identity=29.490022172949, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI4507229, Length=411, Percent_Identity=28.4671532846715, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI310128091, Length=386, Percent_Identity=30.5699481865285, Blast_Score=130, Evalue=7e-30,
Organism=Homo sapiens, GI25777721, Length=424, Percent_Identity=27.3584905660377, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI25952152, Length=431, Percent_Identity=26.6821345707657, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI115387104, Length=439, Percent_Identity=25.7403189066059, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI25777726, Length=449, Percent_Identity=25.1670378619154, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI11095441, Length=421, Percent_Identity=26.1282660332542, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI310128089, Length=322, Percent_Identity=29.1925465838509, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI206597441, Length=463, Percent_Identity=25.7019438444924, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI206597439, Length=463, Percent_Identity=25.7019438444924, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI22907049, Length=463, Percent_Identity=25.7019438444924, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI310128087, Length=276, Percent_Identity=31.1594202898551, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=29.0322580645161, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI310128097, Length=257, Percent_Identity=30.3501945525292, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI301500698, Length=425, Percent_Identity=23.5294117647059, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI71773324, Length=394, Percent_Identity=24.3654822335025, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI4502043, Length=324, Percent_Identity=24.0740740740741, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI238814371, Length=324, Percent_Identity=24.0740740740741, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI73695881, Length=324, Percent_Identity=24.3827160493827, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI73695879, Length=324, Percent_Identity=24.3827160493827, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI73466520, Length=364, Percent_Identity=25.5494505494505, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI4557303, Length=364, Percent_Identity=25.5494505494505, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI310128101, Length=216, Percent_Identity=30.0925925925926, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI310128099, Length=216, Percent_Identity=30.0925925925926, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787250, Length=1236, Percent_Identity=57.3624595469256, Blast_Score=1305, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=448, Percent_Identity=28.5714285714286, Blast_Score=166, Evalue=9e-42,
Organism=Escherichia coli, GI1788042, Length=452, Percent_Identity=31.6371681415929, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1787715, Length=443, Percent_Identity=30.2483069977427, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI87081896, Length=466, Percent_Identity=30.4721030042918, Blast_Score=154, Evalue=3e-38,
Organism=Escherichia coli, GI1787558, Length=427, Percent_Identity=29.5081967213115, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1787684, Length=464, Percent_Identity=29.0948275862069, Blast_Score=143, Evalue=7e-35,
Organism=Escherichia coli, GI1786504, Length=456, Percent_Identity=27.4122807017544, Blast_Score=135, Evalue=2e-32,
Organism=Escherichia coli, GI87082295, Length=462, Percent_Identity=27.7056277056277, Blast_Score=133, Evalue=6e-32,
Organism=Escherichia coli, GI87081926, Length=441, Percent_Identity=26.530612244898, Blast_Score=133, Evalue=8e-32,
Organism=Escherichia coli, GI1787653, Length=266, Percent_Identity=24.812030075188, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI133930964, Length=557, Percent_Identity=27.8276481149013, Blast_Score=169, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17534447, Length=460, Percent_Identity=31.0869565217391, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=451, Percent_Identity=30.5986696230599, Blast_Score=163, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI25144435, Length=451, Percent_Identity=30.3769401330377, Blast_Score=161, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17562198, Length=448, Percent_Identity=29.6875, Blast_Score=161, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI32564736, Length=405, Percent_Identity=30.3703703703704, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI115532534, Length=343, Percent_Identity=33.5276967930029, Blast_Score=150, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=469, Percent_Identity=27.5053304904051, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=469, Percent_Identity=27.5053304904051, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17551164, Length=433, Percent_Identity=26.0969976905312, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32564151, Length=409, Percent_Identity=29.3398533007335, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71995606, Length=434, Percent_Identity=26.2672811059908, Blast_Score=131, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=456, Percent_Identity=26.9736842105263, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71995613, Length=391, Percent_Identity=25.8312020460358, Blast_Score=122, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71986308, Length=422, Percent_Identity=26.7772511848341, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=297, Percent_Identity=27.9461279461279, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=359, Percent_Identity=24.7910863509749, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25146391, Length=370, Percent_Identity=23.5135135135135, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=370, Percent_Identity=23.5135135135135, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=370, Percent_Identity=23.5135135135135, Blast_Score=84, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=449, Percent_Identity=34.075723830735, Blast_Score=209, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6325196, Length=454, Percent_Identity=30.1762114537445, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6321826, Length=476, Percent_Identity=28.781512605042, Blast_Score=171, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=450, Percent_Identity=27.1111111111111, Blast_Score=165, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=440, Percent_Identity=29.0909090909091, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6323822, Length=438, Percent_Identity=27.8538812785388, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319478, Length=433, Percent_Identity=26.5588914549654, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6321828, Length=472, Percent_Identity=22.2457627118644, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323757, Length=324, Percent_Identity=26.2345679012346, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281362580, Length=445, Percent_Identity=30.1123595505618, Blast_Score=182, Evalue=9e-46,
Organism=Drosophila melanogaster, GI62472918, Length=445, Percent_Identity=30.1123595505618, Blast_Score=182, Evalue=9e-46,
Organism=Drosophila melanogaster, GI62472926, Length=445, Percent_Identity=30.1123595505618, Blast_Score=182, Evalue=9e-46,
Organism=Drosophila melanogaster, GI62472936, Length=445, Percent_Identity=30.1123595505618, Blast_Score=182, Evalue=9e-46,
Organism=Drosophila melanogaster, GI21356737, Length=445, Percent_Identity=30.1123595505618, Blast_Score=182, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24585660, Length=504, Percent_Identity=26.984126984127, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24668425, Length=531, Percent_Identity=26.5536723163842, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24668417, Length=531, Percent_Identity=26.5536723163842, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24668413, Length=531, Percent_Identity=26.5536723163842, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI20129399, Length=434, Percent_Identity=28.5714285714286, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24650465, Length=449, Percent_Identity=28.0623608017817, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666674, Length=442, Percent_Identity=28.9592760180996, Blast_Score=143, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28574525, Length=488, Percent_Identity=26.4344262295082, Blast_Score=129, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571806, Length=437, Percent_Identity=25.858123569794, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28571802, Length=437, Percent_Identity=25.858123569794, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28571800, Length=437, Percent_Identity=25.858123569794, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28571798, Length=434, Percent_Identity=25.8064516129032, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28571796, Length=434, Percent_Identity=25.8064516129032, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28571794, Length=434, Percent_Identity=25.8064516129032, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24638876, Length=425, Percent_Identity=25.8823529411765, Blast_Score=103, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24638878, Length=425, Percent_Identity=25.8823529411765, Blast_Score=103, Evalue=7e-22,
Organism=Drosophila melanogaster, GI281360299, Length=346, Percent_Identity=28.6127167630058, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281360297, Length=346, Percent_Identity=28.6127167630058, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281360295, Length=346, Percent_Identity=28.6127167630058, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24586250, Length=346, Percent_Identity=28.6127167630058, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281360301, Length=335, Percent_Identity=28.6567164179104, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI45552499, Length=346, Percent_Identity=28.0346820809249, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281360303, Length=346, Percent_Identity=28.0346820809249, Blast_Score=98, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 133486; Mature: 133355

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTAACPRFLRSAITHAYRHNETESVNGLLRQIDWPPCSRARAEELARKLVTSMRGKYS
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
HRGGVDALMHEFSLSSQEGVALMCLAEALLRIPDRETADRLIRDKISKGDWRVHVGHSPS
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCC
LFVNAAAWGLLISRKLVSTHREDGLSAALSGLMEKGGEPLIRKGMDLAMRMLGHQFVIGE
EEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHH
TIEEALERSREREMRGYRYSYDMLGEAAITEADAQRYWTSYASAIHAIGKSRGKGGIKSG
HHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHC
IYRGPGISVKLSALHPRYVRSQRERVMSELLPRLKSLLLLAKHYDMGFNMDAEEADRLDL
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SLDLLEALVFDPDLAGWDGIGFVVQAYQKRCPFVVDWLIDLARRSGHRLMVRLVKGAYWD
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCCC
GEIKRAQVEGLDGYPVYTRKIHTDICYMVCAQKLLRAAEAVFPQFATHNAHTLSAVYQIA
CCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QDADIEDYEFQYLHGMGETLYDQVELLKEDRFVKPCRIYAPVGSYETLLAYLARRLLENG
HCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
ANSSFVNRILDDDIVVEELVADPVSQIEQEGVHPHPAIPLPGDLYGHKRRNSAGLDFSDE
CCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QALAALSAELTEMERREWRARPVLAAGGNAGNAGSRVLNPADRNDSAGTVVEATEHDVED
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHH
AIAVAHAFVAEWQSVSHEARAAMLERAADALEAHRTELMGLAIREAGKSLPDAVAEVREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VDFCRYYGQQIRDWPNMSPSSALGPVVCISPWNFPLAIFIGQVSAALAAGNPVLAKPAEQ
HHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
TPLIAAVAVRLLHAAGIPRAALQLLPGQGERVGEQLVKDVRVRGVIFTGSTEVAQLICRT
CHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCHHHHHHHHHH
LALRAQKSEILFIAETGGQNAMIVDSSARIEQVVQDALTSAFDSAGQRCSALRVLCLQED
HHHHCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAEQVLEVLRGAMGELTVGDPRELATDVGPVIDADAQHALLDHIEKMRAAGHTVFQAALP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVCANGTFVAPTLIEIDHIDELEREVFGPVLHVVRFARERVDELVGQINATGYGLTHGIH
HHHCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
SRVDETIDFITKRVHAGNIYVNRNMIGAVVGVQPFGGEGKSGTGPKAGGPLYLHRLMPQT
HHHHHHHHHHHHHHHCCEEEEECCCEEHEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCC
PLLLADNGGLRVNSPPVELQVLAAWARQAGRDVLASLCEDYAMRTPFAFSIPLPGPTGES
CEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
NTLKFAPRRAVACIAVDEDALLEQMAAALATGNQIILADNPPLRALLDKLPSQVRNRLRI
CCEEECCCCEEEEEEECHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
EREWIHAPVSAVLYSGPEDEAYRLRNELAGREGALVAFITASGTDFPLYRLTAERVVSVN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHCCHHHHEEEE
TTAAGGNPGLMGLDFNGSSTH
CCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
GKTAACPRFLRSAITHAYRHNETESVNGLLRQIDWPPCSRARAEELARKLVTSMRGKYS
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
HRGGVDALMHEFSLSSQEGVALMCLAEALLRIPDRETADRLIRDKISKGDWRVHVGHSPS
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCC
LFVNAAAWGLLISRKLVSTHREDGLSAALSGLMEKGGEPLIRKGMDLAMRMLGHQFVIGE
EEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHH
TIEEALERSREREMRGYRYSYDMLGEAAITEADAQRYWTSYASAIHAIGKSRGKGGIKSG
HHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHC
IYRGPGISVKLSALHPRYVRSQRERVMSELLPRLKSLLLLAKHYDMGFNMDAEEADRLDL
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SLDLLEALVFDPDLAGWDGIGFVVQAYQKRCPFVVDWLIDLARRSGHRLMVRLVKGAYWD
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCCC
GEIKRAQVEGLDGYPVYTRKIHTDICYMVCAQKLLRAAEAVFPQFATHNAHTLSAVYQIA
CCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QDADIEDYEFQYLHGMGETLYDQVELLKEDRFVKPCRIYAPVGSYETLLAYLARRLLENG
HCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
ANSSFVNRILDDDIVVEELVADPVSQIEQEGVHPHPAIPLPGDLYGHKRRNSAGLDFSDE
CCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QALAALSAELTEMERREWRARPVLAAGGNAGNAGSRVLNPADRNDSAGTVVEATEHDVED
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHH
AIAVAHAFVAEWQSVSHEARAAMLERAADALEAHRTELMGLAIREAGKSLPDAVAEVREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VDFCRYYGQQIRDWPNMSPSSALGPVVCISPWNFPLAIFIGQVSAALAAGNPVLAKPAEQ
HHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
TPLIAAVAVRLLHAAGIPRAALQLLPGQGERVGEQLVKDVRVRGVIFTGSTEVAQLICRT
CHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCHHHHHHHHHH
LALRAQKSEILFIAETGGQNAMIVDSSARIEQVVQDALTSAFDSAGQRCSALRVLCLQED
HHHHCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAEQVLEVLRGAMGELTVGDPRELATDVGPVIDADAQHALLDHIEKMRAAGHTVFQAALP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVCANGTFVAPTLIEIDHIDELEREVFGPVLHVVRFARERVDELVGQINATGYGLTHGIH
HHHCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
SRVDETIDFITKRVHAGNIYVNRNMIGAVVGVQPFGGEGKSGTGPKAGGPLYLHRLMPQT
HHHHHHHHHHHHHHHCCEEEEECCCEEHEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCC
PLLLADNGGLRVNSPPVELQVLAAWARQAGRDVLASLCEDYAMRTPFAFSIPLPGPTGES
CEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
NTLKFAPRRAVACIAVDEDALLEQMAAALATGNQIILADNPPLRALLDKLPSQVRNRLRI
CCEEECCCCEEEEEEECHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
EREWIHAPVSAVLYSGPEDEAYRLRNELAGREGALVAFITASGTDFPLYRLTAERVVSVN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHCCHHHHEEEE
TTAAGGNPGLMGLDFNGSSTH
CCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]