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The map label for this gene is yicE [H]

Identifier: 82546077

GI number: 82546077

Start: 3738111

End: 3739502

Strand: Reverse

Name: yicE [H]

Synonym: SBO_3723

Alternate gene names: 82546077

Gene position: 3739502-3738111 (Counterclockwise)

Preceding gene: 82546079

Following gene: 82546076

Centisome position: 82.74

GC content: 54.89

Gene sequence:

>1392_bases
ATGTCTGTTTCCACCCTCGAGTCAGAAAATGCGCAACCGGTTGCGCAGACTCAAAACAGCGAACTGATTTACCGTCTTGA
AGATCGTCCGCCGCTTCCTCAAACCCTGTTTGCCGCCTGTCAGCATCTGCTGGCGATGTTCGTTGCGGTGATCACGCCAG
CGCTATTAATCTGCCAGGCGCTGGGTTTACCGGCACAAGACACGCAACACATTATTAGTATGTCGCTGTTTGCCTCCGGT
GTGGCATCGATTATTCAAATTAAGACCTGGGGTCCGGTTGGCTCCGGGCTGTTGTCTATTCAGGGCACCAGCTTCAACTT
TGTTGCCCCGCTGATTATGGGCGGTACCGCGCTGAAAACCGGTGGTGCTGATGTTCCTACCATGATGGCGGCTTTGTTCG
GCACGTTGATGCTGGCAAGTTGCACCGAGATGGTGATCTCCCGCGTTCTGCATCTGGCGCGCCGCATTATTACGCCGCTG
GTTTCTGGCGTTGTGGTGATGATTATCGGCCTGTCGCTAATTCAGGTTGGGTTAACGTCCATTGGCGGCGGTTACGCAGC
CATGAGCGATAACACCTTCGGCGCACCGAAAAATCTGCTGCTGGCAGGCGTGGTCTTAGCCTTAATTATCCTGCTTAACC
GTCAACGTAACCCTTACTTACGCGTGGCCTCACTGGTGATTGCGATGGCGGCCGGATATGCGCTGGCGTGGTTTATGGGC
ATGTTGCCAGAAAGCAACGAACCGATGACGCAAGAACTGATTATGGTGCCAACGCCGCTCTATTACGGTCTTGGCATTGA
ATGGAGTCTGCTGCTGCCGCTGATGCTGGTCTTTATGATCACTTCGCTGGAAACCATTGGCGATATCACGTCGACCTCTG
ACGTTTCCGAACAGCCAGTGTCCGGTCCGCTGTACATGAAACGCCTGAAAGGCGGCGTGCTGGCAAACGGCCTGAACTCG
TTTGTTTCGGCGGTGTTTAACACCTTCCCGAACTCCTGCTTCGGGCAAAACAACGGAGTGATCCAGTTGACTGGTGTTGC
CAGCCGCTATGTCGGTTTTGTCGTCGCGCTGATGTTGATCGTGCTGGGTCTGTTCCCGGCAGTGAGCGGTTTTGTACAAC
ACATTCCAGAACCGGTTCTGGGCGGCGCAACGCTTGTAATGTTTGGCACCATCGCCGCCTCCGGTGTGCGTATCGTTTCT
CGTGAGCCGCTGAACCGTCGGGCGATTCTGATTATCGCGCTGTCGCTGGCGGTTGGTCTGGGCGTGTCTCAGCAGCCGCT
GATTTTGCAGTTTGCCCCTGAATGGCTGAAAAACCTGCTCTCCTCCGGGATCGCCGCGGGCGGTATTACTGCCATCGTGC
TGAATCTGATTTTCCCACCAGAAAAACAGTAA

Upstream 100 bases:

>100_bases
ATTTATCTCATTTAAATATTTAGATGAGGATGTGGCAAACGTTTGCTTTTCTCTTTCGGTCAGCTAAAATGCCCGCTTTG
CTACCACGGGATTGTTTTCG

Downstream 100 bases:

>100_bases
TTCACTGGCGGCGGTAAGATAATTACCGCCGCAGTCTCACCTCTTTCACCATTCCCGCCTTGAGGATTGCGCGTAAATCG
TGCATAACTCTCTTATGTGC

Product: transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQALGLPAQDTQHIISMSLFASG
VASIIQIKTWGPVGSGLLSIQGTSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNPYLRVASLVIAMAAGYALAWFMG
MLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLMLVFMITSLETIGDITSTSDVSEQPVSGPLYMKRLKGGVLANGLNS
FVSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIAASGVRIVS
REPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGITAIVLNLIFPPEKQ

Sequences:

>Translated_463_residues
MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQALGLPAQDTQHIISMSLFASG
VASIIQIKTWGPVGSGLLSIQGTSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNPYLRVASLVIAMAAGYALAWFMG
MLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLMLVFMITSLETIGDITSTSDVSEQPVSGPLYMKRLKGGVLANGLNS
FVSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIAASGVRIVS
REPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGITAIVLNLIFPPEKQ
>Mature_462_residues
SVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQALGLPAQDTQHIISMSLFASGV
ASIIQIKTWGPVGSGLLSIQGTSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPLV
SGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNPYLRVASLVIAMAAGYALAWFMGM
LPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLMLVFMITSLETIGDITSTSDVSEQPVSGPLYMKRLKGGVLANGLNSF
VSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIAASGVRIVSR
EPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGITAIVLNLIFPPEKQ

Specific function: Specific, proton motive force-dependent high-affinity transporter for xanthine [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=516, Percent_Identity=22.8682170542636, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI40316845, Length=516, Percent_Identity=22.8682170542636, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1790087, Length=463, Percent_Identity=99.5680345572354, Blast_Score=912, Evalue=0.0,
Organism=Escherichia coli, GI87082178, Length=444, Percent_Identity=44.8198198198198, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI87082181, Length=460, Percent_Identity=28.4782608695652, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788843, Length=444, Percent_Identity=25.6756756756757, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081818, Length=410, Percent_Identity=24.390243902439, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48915; Mature: 48784

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQA
CCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLPAQDTQHIISMSLFASGVASIIQIKTWGPVGSGLLSIQGTSFNFVAPLIMGGTALKT
HCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCHHHHHHHHCCCCCCC
GGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPLVSGVVVMIIGLSLIQVGLTS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNPYLRVASLVIAMAAGYALAWFMG
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLMLVFMITSLETIGDITSTSDVSEQPV
HCCCCCCCHHHHHEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLI
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHH
VLGLFPAVSGFVQHIPEPVLGGATLVMFGTIAASGVRIVSREPLNRRAILIIALSLAVGL
HHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHC
GVSQQPLILQFAPEWLKNLLSSGIAAGGITAIVLNLIFPPEKQ
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQA
CCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLPAQDTQHIISMSLFASGVASIIQIKTWGPVGSGLLSIQGTSFNFVAPLIMGGTALKT
HCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCHHHHHHHHCCCCCCC
GGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPLVSGVVVMIIGLSLIQVGLTS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNPYLRVASLVIAMAAGYALAWFMG
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLMLVFMITSLETIGDITSTSDVSEQPV
HCCCCCCCHHHHHEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLI
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHH
VLGLFPAVSGFVQHIPEPVLGGATLVMFGTIAASGVRIVSREPLNRRAILIIALSLAVGL
HHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHC
GVSQQPLILQFAPEWLKNLLSSGIAAGGITAIVLNLIFPPEKQ
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]