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The map label for this gene is yiaY [H]

Identifier: 82545951

GI number: 82545951

Start: 3597578

End: 3598729

Strand: Reverse

Name: yiaY [H]

Synonym: SBO_3589

Alternate gene names: 82545951

Gene position: 3598729-3597578 (Counterclockwise)

Preceding gene: 82545952

Following gene: 82545950

Centisome position: 79.62

GC content: 50.26

Gene sequence:

>1152_bases
ATGGCATCTTCAACTTTCTTTATTCCTTCTGTGAATGTCATCGGCGCTGATTCATTGACTGATGCAATGAATATGATGGC
AGATTATGGATTTACCCGTACCTTAATTGTCACTGACAGTATGTTAACGAAATTAGGTATGGCGGGCGATGTGCAAAAAG
CACTGGAAGAACGCAATATTTTTAGCGTTATTTATGATGGCACCCAACCTAACCCCACCACGGAAAACGTCGCCGCAGGT
TTGAAATTACTTAAAGAGAATAATTGCGATAGCGTGATCTCCTTAGGCGGTGGTTCTCCACACGACTGCGCAAAAGGTAT
TGCGCTGGTGGCAGCCAATGGCGGCGATATTCGCGATTACGAAGGCGTTGACCGCTCTGCAAAACCGCAGCTGCCGATGA
TCGCCATCAACACCACTGCGGGTACGGCCTCTGAAATGACCCGTTTCTGCATCATCACTGACGAAGCGCGTCATATCAAA
ATGGCGATTGTTGATAAACATGTCACTCCGCTGCTTTCTGTCAATGACTCCTCTCTGATGATTGGTATGCCGAAGTCACT
GACCGCCGCAACGGGTATGGATGCCTTAACGCACGCTATCGAAGCATATGTTTCTATTGCCGCCACGCCGATCACTGACG
CTTGTGCACTGAAAGCCGTGACCATGATTGCCGAAAACCTGCCGTTAGCCGTTGAAGATGGCAGTAATGCGAAAGCGCGT
GAAGCAATGGCTTATGCCCAGTTCCTTGCCGGTATGGCGTTCAATAATGCTTCTCTGGGTTATGTTCATGCGATGGCGTA
CCAGCTGGGCGGTTTCTACAACCTGCCACACGGTGTATGTAACGCCGTTCTGCTGCCCCATGTTCAGGTATTCAACAGCA
AAGTCGCCGCTGCACGTCTGCGTGACTGTGCCGCTGCAATGGGCGTGAACGTGACAGGTAAAAACGACGCGGAAGGTGCT
GAAGCCTGCATTAACGCCATCCGTGAACTGGCGAAGAAAGTGGATATCCCGGCAGGCCTACGCGACCTGAACGTGAAAGA
AGAAGATTTCGCGGTTCTGGCGACTAATGCCCTGAAAGATGCCTGTGGTTTTACTAACCCGATCCAGGCAACTCACGAAG
AAATTGTGGCGATTTATCGCGCAGCGATGTAA

Upstream 100 bases:

>100_bases
TTTATTAGATTAATTTTGATAATTAATAATAATGATCATGTTTTCGAATGAAAATCCTCAGTAAGCTTCCCACCCTTTTT
TACACTTTCAGGAGTGTGTT

Downstream 100 bases:

>100_bases
TCATCATTTCCACAACGGCTGGCAAATTGTCAGCCGCTTTTTCAACTATCTCTGTAACCCTTGCCCGTAAATTCGTGATA
GCCGTCGTAAAGCTGTTACC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDSMLTKLGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAG
LKLLKENNCDSVISLGGGSPHDCAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALKAVTMIAENLPLAVEDGSNAKAR
EAMAYAQFLAGMAFNNASLGYVHAMAYQLGGFYNLPHGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGA
EACINAIRELAKKVDIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM

Sequences:

>Translated_383_residues
MASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDSMLTKLGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAG
LKLLKENNCDSVISLGGGSPHDCAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALKAVTMIAENLPLAVEDGSNAKAR
EAMAYAQFLAGMAFNNASLGYVHAMAYQLGGFYNLPHGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGA
EACINAIRELAKKVDIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM
>Mature_382_residues
ASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDSMLTKLGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAGL
KLLKENNCDSVISLGGGSPHDCAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIKM
AIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALKAVTMIAENLPLAVEDGSNAKARE
AMAYAQFLAGMAFNNASLGYVHAMAYQLGGFYNLPHGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAE
ACINAIRELAKKVDIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=398, Percent_Identity=24.8743718592965, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI48994951, Length=383, Percent_Identity=99.2167101827676, Blast_Score=778, Evalue=0.0,
Organism=Escherichia coli, GI1789163, Length=356, Percent_Identity=43.5393258426966, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI87082107, Length=378, Percent_Identity=37.037037037037, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1787493, Length=383, Percent_Identity=33.9425587467363, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789386, Length=309, Percent_Identity=26.2135922330097, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=396, Percent_Identity=24.7474747474747, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=383, Percent_Identity=55.3524804177546, Blast_Score=424, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24657991, Length=423, Percent_Identity=24.822695035461, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40367; Mature: 40236

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDSMLTKLGMAGDVQKALEERNI
CCCCEEECCCCCEECCHHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCHHHHHHHHHCCE
FSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHDCAKGIALVAANGGDIRDY
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHCCEEEEEECCCCCCCC
EGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIKMAIVDKHVTPLLSVNDSSLM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEECCCCCCEEEECCCEEE
IGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALKAVTMIAENLPLAVEDGSNAKAR
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHH
EAMAYAQFLAGMAFNNASLGYVHAMAYQLGGFYNLPHGVCNAVLLPHVQVFNSKVAAARL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDCAAAMGVNVTGKNDAEGAEACINAIRELAKKVDIPAGLRDLNVKEEDFAVLATNALKD
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHH
ACGFTNPIQATHEEIVAIYRAAM
HHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDSMLTKLGMAGDVQKALEERNI
CCCEEECCCCCEECCHHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCHHHHHHHHHCCE
FSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHDCAKGIALVAANGGDIRDY
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHCCEEEEEECCCCCCCC
EGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIKMAIVDKHVTPLLSVNDSSLM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEECCCCCCEEEECCCEEE
IGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALKAVTMIAENLPLAVEDGSNAKAR
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHH
EAMAYAQFLAGMAFNNASLGYVHAMAYQLGGFYNLPHGVCNAVLLPHVQVFNSKVAAARL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDCAAAMGVNVTGKNDAEGAEACINAIRELAKKVDIPAGLRDLNVKEEDFAVLATNALKD
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHH
ACGFTNPIQATHEEIVAIYRAAM
HHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]