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The map label for this gene is apr [H]

Identifier: 78779568

GI number: 78779568

Start: 1102422

End: 1105097

Strand: Reverse

Name: apr [H]

Synonym: PMT9312_1185

Alternate gene names: 78779568

Gene position: 1105097-1102422 (Counterclockwise)

Preceding gene: 78779570

Following gene: 78779567

Centisome position: 64.66

GC content: 30.04

Gene sequence:

>2676_bases
ATGAGCAATAAAAAAGAAGGCTCATCAGGTAGTTTTGATAAATTAAACACTGATAACAATAACAATAAAAAAAATCTTTC
GAAACAAAATAGTGAAGTTGAAAATGGATTAAATAAGCTAGAAAATAATAAAAGTAATACAGAAATAAATTTAATTAAAC
AAATATCAACTGAAGGAGAATCATATGAGATTGAATATTCAATTGATCAAATACAGAATCCTATAGATAAAAGTTCAGAT
TTAAAACAATTTAATCTAGAAAGAATTCGAAAATTGCAAACATTTGATTTGGAATATAAAAATAAATACTACGAAGATTA
TTTTAATTCGTATTCAATAGATAGTTATGAAAATCAAGAAATTTCTTTAATTCAATTTAATCAAAATACAATTATAGATT
TTAAAAATTCAGAAAATATACTTGAACGAACAAAATCATCTTCAGGTTCAGGATGTGGTAATCAGGAAATTCCTACTCCT
ATAAATTTTTCAAGTACAGATGGCTATGGACATGCAAATATTGAAAGGGCATTTGAGATTCTTAAAGGGATTGATATCTC
TTCAAAGGATGATTTGGGAGGTAATTTATGGGGTTTAGATAATATTGGAGCCCCTGAGGTTTGGACAAGTACAGGATGTT
TTAGTGGCAGTACGGGAAAAGATGTTGTTGTAGCTGTATTAGATACTGGTCTTGATTATAGTCATTCTGAATTTTCTGGG
AGAATTGTAGATGGATATGATTTTATTGATAATGATAATATTGCACAAGATGTGCATGGACATGGTACTCATTGTTCAGG
AACTATATTAGGAGCTAATGATGGAGTGGGAATTACAGGAGTTGCTTATGATGCAAAAATTATGCCAATTAAAGTTTTAA
ATGATAGTGGCCGTGGATCGATAGCAGGAATAGTTGCTGGTATGAGATGGGCGGTAGATAATGGAGCTGATGTACTTAAT
CTTTCTTTAGGGGGTGGCGCGCCTAATAGCGATTATTTGGATGCTTTAAAATATGCTGCAGATAATGGGGTTGTGGTTGC
GATGGCTTCAGGAAATTCTTCCTCTAGTGCTCCTTTATGGCCTGCTAGATATGCTACGGATTATGGAATAGCAGTTGGTG
CTGTTGATATAAACAAAAATGATGCTTATTTTTCTAATCGCGCTGGCAACACCACGATGGATTATGTATCTGCACCTGGT
GTAAATGTTTATTCTTCTCTTCCTGGAGGAGGATATGAAAGTTGGAATGGAACTTCAATGGCTGCTCCGCATGTTGCTGG
AATGGCTGCATTATTGAAAAGTTATGATAAAACTTTAACTCCATTACAAATAGAAACTTTAATTTCTGCATCAGCGTCTA
ATTCGGATTCAAACTCATCTAATAATTCAAATAATTATTTTGAATCCAATTCAGAATTTAATATGTTCTATTCCAAAGAC
TTTGATGATTTGTTCTTTGAATCTAACGAATTAATCTCAGGTTATGAATATAGTTTTGATTCAAACTCATCTGGTTCAGA
TTATTTGGATTGGGCCCTAGATTTAATTGGTGAGAATAATGAAAAAATGTACATAGCAGGAACAGATGGATTTTATGAAA
ACCAAAGTAAAAATAAAATTGAAGAATTAAATTCTTTTATTGATGAAATTAATCAAGGAGTAGAAGATAAAGAAGAAGAG
ATAGCATATGCGGGCGGAACAGATGGATTTTATGAAAACCAAAGTAAAAATAAAATTGAAGAATTAAATTCTTTTATTGA
TGAAATTAATCAAGGAGTAGAAGATAAAGAAGAAGAGATAGCATATGCGGGCGGAACAGATGGATTTTATGAAAACCAAA
GTAAAAATAAAATTGAAGAATTAAATTCTTTTATTGATGAAATTAATCAAGGAGTAGAAGATAAAGAAGAAGAGATAGCA
TATGCGGGCGGAACAGATGGATTTTATGAAAACCAAAGTAAAAATAAAATTGAAGAATTAAATTCTTTTATTGATGAAAT
TAATCAAGGAGTAGAAGATAAAGAAGAAGAGATAGCATATGCGGGCGGAACAGATGGATTTTATGAAAACCAAAGTAAAA
ATAAAATTGAAGAATTAAATTCTTTTATTGATGAAATTAATCAAGGAGTAGAAGATAAAGAAGAAGAGATAGCATATGCG
GGCGGAACAGATGGATTTTATGAAAACCAAAGTAAAAATAAAATTGAAGAATTAAATTCTTTTATTGATGAAATTAATCA
AGGAGTAGAAGATAAAGAAGAAGAGATAGCATATGCGGGCGGAACAGATGGATTTTATGAAAACCAAAGTAAAAATAAAA
TTGAAGAATTAAATTCTTTTATTGATGAAATTAATCAAGGAGTAGAAGATAAAGAAGAAGAGATAGCATATGCGGGCGGA
ACAGATGGATTTTATGAAAACCAAAGTAAAAATAAAATTGAAGAATTAAATTCTTTTATTGATGAAATTAATCAAGGAGT
AGAAGATAAAGAAGAAGAGATAGCATATGCGGGCGGAACAGATGGATTTTATGAAAACCAAAGTAAAAATGGAACTATTT
TGGGTTTTAACTCTAATTTAGAAAATGAAAATAATCTTTTTGAAGATAATTTAATTTTGAGTAATAATGGTTTCCAAAAT
TATTTAGAAAATCAAAATAATAATTATTCTGTTTAA

Upstream 100 bases:

>100_bases
ATTTTTGGGATAAAAGATTTTTCTTTTAAATTATAATTTTAAAAATAAAATTGCCAATTCTATAAAAAACTAATATATTT
AATGAATAAATGAGTAGTTT

Downstream 100 bases:

>100_bases
CAAGTTAATTGATAGAAAGCTTTCTCCTGTCATGTTTTTTAAATGCCAAACAGCCTGTATTTATTTCTATGGATTATCAG
AATTTTATTGTTAAAGGTTT

Product: subtilisin-like serine protease-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 891; Mature: 890

Protein sequence:

>891_residues
MSNKKEGSSGSFDKLNTDNNNNKKNLSKQNSEVENGLNKLENNKSNTEINLIKQISTEGESYEIEYSIDQIQNPIDKSSD
LKQFNLERIRKLQTFDLEYKNKYYEDYFNSYSIDSYENQEISLIQFNQNTIIDFKNSENILERTKSSSGSGCGNQEIPTP
INFSSTDGYGHANIERAFEILKGIDISSKDDLGGNLWGLDNIGAPEVWTSTGCFSGSTGKDVVVAVLDTGLDYSHSEFSG
RIVDGYDFIDNDNIAQDVHGHGTHCSGTILGANDGVGITGVAYDAKIMPIKVLNDSGRGSIAGIVAGMRWAVDNGADVLN
LSLGGGAPNSDYLDALKYAADNGVVVAMASGNSSSSAPLWPARYATDYGIAVGAVDINKNDAYFSNRAGNTTMDYVSAPG
VNVYSSLPGGGYESWNGTSMAAPHVAGMAALLKSYDKTLTPLQIETLISASASNSDSNSSNNSNNYFESNSEFNMFYSKD
FDDLFFESNELISGYEYSFDSNSSGSDYLDWALDLIGENNEKMYIAGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEE
IAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIA
YAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYA
GGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGG
TDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNGTILGFNSNLENENNLFEDNLILSNNGFQN
YLENQNNNYSV

Sequences:

>Translated_891_residues
MSNKKEGSSGSFDKLNTDNNNNKKNLSKQNSEVENGLNKLENNKSNTEINLIKQISTEGESYEIEYSIDQIQNPIDKSSD
LKQFNLERIRKLQTFDLEYKNKYYEDYFNSYSIDSYENQEISLIQFNQNTIIDFKNSENILERTKSSSGSGCGNQEIPTP
INFSSTDGYGHANIERAFEILKGIDISSKDDLGGNLWGLDNIGAPEVWTSTGCFSGSTGKDVVVAVLDTGLDYSHSEFSG
RIVDGYDFIDNDNIAQDVHGHGTHCSGTILGANDGVGITGVAYDAKIMPIKVLNDSGRGSIAGIVAGMRWAVDNGADVLN
LSLGGGAPNSDYLDALKYAADNGVVVAMASGNSSSSAPLWPARYATDYGIAVGAVDINKNDAYFSNRAGNTTMDYVSAPG
VNVYSSLPGGGYESWNGTSMAAPHVAGMAALLKSYDKTLTPLQIETLISASASNSDSNSSNNSNNYFESNSEFNMFYSKD
FDDLFFESNELISGYEYSFDSNSSGSDYLDWALDLIGENNEKMYIAGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEE
IAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIA
YAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYA
GGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGG
TDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNGTILGFNSNLENENNLFEDNLILSNNGFQN
YLENQNNNYSV
>Mature_890_residues
SNKKEGSSGSFDKLNTDNNNNKKNLSKQNSEVENGLNKLENNKSNTEINLIKQISTEGESYEIEYSIDQIQNPIDKSSDL
KQFNLERIRKLQTFDLEYKNKYYEDYFNSYSIDSYENQEISLIQFNQNTIIDFKNSENILERTKSSSGSGCGNQEIPTPI
NFSSTDGYGHANIERAFEILKGIDISSKDDLGGNLWGLDNIGAPEVWTSTGCFSGSTGKDVVVAVLDTGLDYSHSEFSGR
IVDGYDFIDNDNIAQDVHGHGTHCSGTILGANDGVGITGVAYDAKIMPIKVLNDSGRGSIAGIVAGMRWAVDNGADVLNL
SLGGGAPNSDYLDALKYAADNGVVVAMASGNSSSSAPLWPARYATDYGIAVGAVDINKNDAYFSNRAGNTTMDYVSAPGV
NVYSSLPGGGYESWNGTSMAAPHVAGMAALLKSYDKTLTPLQIETLISASASNSDSNSSNNSNNYFESNSEFNMFYSKDF
DDLFFESNELISGYEYSFDSNSSGSDYLDWALDLIGENNEKMYIAGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEI
AYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAY
AGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAG
GTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGT
DGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNGTILGFNSNLENENNLFEDNLILSNNGFQNY
LENQNNNYSV

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=237, Percent_Identity=31.6455696202532, Blast_Score=69, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324576, Length=239, Percent_Identity=35.9832635983264, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6320775, Length=282, Percent_Identity=32.9787234042553, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6319893, Length=230, Percent_Identity=31.304347826087, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550681, Length=240, Percent_Identity=30.4166666666667, Blast_Score=66, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 98385; Mature: 98254

Theoretical pI: Translated: 3.84; Mature: 3.84

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKKEGSSGSFDKLNTDNNNNKKNLSKQNSEVENGLNKLENNKSNTEINLIKQISTEGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCC
SYEIEYSIDQIQNPIDKSSDLKQFNLERIRKLQTFDLEYKNKYYEDYFNSYSIDSYENQE
CEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCE
ISLIQFNQNTIIDFKNSENILERTKSSSGSGCGNQEIPTPINFSSTDGYGHANIERAFEI
EEEEEECCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LKGIDISSKDDLGGNLWGLDNIGAPEVWTSTGCFSGSTGKDVVVAVLDTGLDYSHSEFSG
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCC
RIVDGYDFIDNDNIAQDVHGHGTHCSGTILGANDGVGITGVAYDAKIMPIKVLNDSGRGS
EEEECCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCEEEEEECCEEEEEEEECCCCCCC
IAGIVAGMRWAVDNGADVLNLSLGGGAPNSDYLDALKYAADNGVVVAMASGNSSSSAPLW
HHHHHHHHHEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
PARYATDYGIAVGAVDINKNDAYFSNRAGNTTMDYVSAPGVNVYSSLPGGGYESWNGTSM
CHHHCCCCCEEEEEEEECCCCCEECCCCCCCCHHHHCCCCCCCEECCCCCCCCCCCCCCC
AAPHVAGMAALLKSYDKTLTPLQIETLISASASNSDSNSSNNSNNYFESNSEFNMFYSKD
CCHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
FDDLFFESNELISGYEYSFDSNSSGSDYLDWALDLIGENNEKMYIAGTDGFYENQSKNKI
CHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHH
EELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEI
HHHHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHE
AYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEEL
EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHH
NSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYA
HHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEEC
GGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSF
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHHH
IDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGT
HHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEECCCC
DGFYENQSKNGTILGFNSNLENENNLFEDNLILSNNGFQNYLENQNNNYSV
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
SNKKEGSSGSFDKLNTDNNNNKKNLSKQNSEVENGLNKLENNKSNTEINLIKQISTEGE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCC
SYEIEYSIDQIQNPIDKSSDLKQFNLERIRKLQTFDLEYKNKYYEDYFNSYSIDSYENQE
CEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCE
ISLIQFNQNTIIDFKNSENILERTKSSSGSGCGNQEIPTPINFSSTDGYGHANIERAFEI
EEEEEECCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LKGIDISSKDDLGGNLWGLDNIGAPEVWTSTGCFSGSTGKDVVVAVLDTGLDYSHSEFSG
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCC
RIVDGYDFIDNDNIAQDVHGHGTHCSGTILGANDGVGITGVAYDAKIMPIKVLNDSGRGS
EEEECCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCEEEEEECCEEEEEEEECCCCCCC
IAGIVAGMRWAVDNGADVLNLSLGGGAPNSDYLDALKYAADNGVVVAMASGNSSSSAPLW
HHHHHHHHHEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
PARYATDYGIAVGAVDINKNDAYFSNRAGNTTMDYVSAPGVNVYSSLPGGGYESWNGTSM
CHHHCCCCCEEEEEEEECCCCCEECCCCCCCCHHHHCCCCCCCEECCCCCCCCCCCCCCC
AAPHVAGMAALLKSYDKTLTPLQIETLISASASNSDSNSSNNSNNYFESNSEFNMFYSKD
CCHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
FDDLFFESNELISGYEYSFDSNSSGSDYLDWALDLIGENNEKMYIAGTDGFYENQSKNKI
CHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHH
EELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEI
HHHHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHE
AYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEEL
EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHH
NSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYA
HHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEEC
GGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSF
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHHH
IDEINQGVEDKEEEIAYAGGTDGFYENQSKNKIEELNSFIDEINQGVEDKEEEIAYAGGT
HHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEECCCC
DGFYENQSKNGTILGFNSNLENENNLFEDNLILSNNGFQNYLENQNNNYSV
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6420308; 9826175 [H]