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The map label for this gene is cobO [H]

Identifier: 78778908

GI number: 78778908

Start: 488883

End: 489575

Strand: Reverse

Name: cobO [H]

Synonym: PMT9312_0523

Alternate gene names: 78778908

Gene position: 489575-488883 (Counterclockwise)

Preceding gene: 78778909

Following gene: 78778907

Centisome position: 28.64

GC content: 33.48

Gene sequence:

>693_bases
ATGCAAGAGCAACCATTATCTTCCGAGAAAATATTCAACCTCGATAATCAAGCCAAAGAACTTGGAATGGGAGGCAAGCT
ATCCCCAGAAAACGATGAGAGCTCATATAAAAAAAGAATGCAGCAAAGAAAAGATATTCAAGCTGAAAGATTACAAATTA
GAAAAACAAAAAAAGGATTATTGATTGTTTTTACGGGGAATGGCAAAGGTAAAACAACTGCATCTTTAGGGATGGCATTA
AGGACAATAGGGCACGGTTATAAAGTAGCAATTATTCAATTTATTAAAGGGGGCTGGACCACTGGAGAAGAAAAAGCACT
GAAGAATTTGTCTTCAAACATATCTTGGCATTCATTAGGAGAGGGATTTACTTGGGAAACACAAGATAGAATTAGGGATG
AAAAATTAGTTCAAGAAGCATGGCGACTTGCCAAAAAATATATTAAGAATGATTCTTATAAACTTATAATCCTTGATGAA
ATTAATATAGCTACAAAACTTGGCTATCTTGCTTCAGAAGAAATAATCACCTTTTTTAAAAGTTTAAATAATAGAAAAAA
TCATGTTGTTTTAACTGGAAGGGGAGCATCTGATTCTATTATCAATTACGCTGATCTAGTTACAGAAATGAAGCTAATAA
GACATCCTTTCAAAGAACAAGGAATAAAAGCTCAAAAGTGCGTTGAGTTCTAG

Upstream 100 bases:

>100_bases
TAAAAGAGATCAACAACAGGCAGTCAATAATGCACTTTTAAGAGTTAAGAGAGCTAAAAGTCTTTAAAGATTTATAATCA
CTTAATAAAATTAGAGTTAT

Downstream 100 bases:

>100_bases
TTAAAACAAATTTTTAATTAATTTCTTCAGATAGGTTTAGAAATGTTTAAAGACGCAAGCAATATCTGAACAAAAAATAA
ATTCGGTACATTTACTTGCT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MQEQPLSSEKIFNLDNQAKELGMGGKLSPENDESSYKKRMQQRKDIQAERLQIRKTKKGLLIVFTGNGKGKTTASLGMAL
RTIGHGYKVAIIQFIKGGWTTGEEKALKNLSSNISWHSLGEGFTWETQDRIRDEKLVQEAWRLAKKYIKNDSYKLIILDE
INIATKLGYLASEEIITFFKSLNNRKNHVVLTGRGASDSIINYADLVTEMKLIRHPFKEQGIKAQKCVEF

Sequences:

>Translated_230_residues
MQEQPLSSEKIFNLDNQAKELGMGGKLSPENDESSYKKRMQQRKDIQAERLQIRKTKKGLLIVFTGNGKGKTTASLGMAL
RTIGHGYKVAIIQFIKGGWTTGEEKALKNLSSNISWHSLGEGFTWETQDRIRDEKLVQEAWRLAKKYIKNDSYKLIILDE
INIATKLGYLASEEIITFFKSLNNRKNHVVLTGRGASDSIINYADLVTEMKLIRHPFKEQGIKAQKCVEF
>Mature_230_residues
MQEQPLSSEKIFNLDNQAKELGMGGKLSPENDESSYKKRMQQRKDIQAERLQIRKTKKGLLIVFTGNGKGKTTASLGMAL
RTIGHGYKVAIIQFIKGGWTTGEEKALKNLSSNISWHSLGEGFTWETQDRIRDEKLVQEAWRLAKKYIKNDSYKLIILDE
INIATKLGYLASEEIITFFKSLNNRKNHVVLTGRGASDSIINYADLVTEMKLIRHPFKEQGIKAQKCVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=200, Percent_Identity=37.5, Blast_Score=153, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 26153; Mature: 26153

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEQPLSSEKIFNLDNQAKELGMGGKLSPENDESSYKKRMQQRKDIQAERLQIRKTKKGL
CCCCCCCCCHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCE
LIVFTGNGKGKTTASLGMALRTIGHGYKVAIIQFIKGGWTTGEEKALKNLSSNISWHSLG
EEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCC
EGFTWETQDRIRDEKLVQEAWRLAKKYIKNDSYKLIILDEINIATKLGYLASEEIITFFK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
SLNNRKNHVVLTGRGASDSIINYADLVTEMKLIRHPFKEQGIKAQKCVEF
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCCHHHHCCC
>Mature Secondary Structure
MQEQPLSSEKIFNLDNQAKELGMGGKLSPENDESSYKKRMQQRKDIQAERLQIRKTKKGL
CCCCCCCCCHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCE
LIVFTGNGKGKTTASLGMALRTIGHGYKVAIIQFIKGGWTTGEEKALKNLSSNISWHSLG
EEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCC
EGFTWETQDRIRDEKLVQEAWRLAKKYIKNDSYKLIILDEINIATKLGYLASEEIITFFK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
SLNNRKNHVVLTGRGASDSIINYADLVTEMKLIRHPFKEQGIKAQKCVEF
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]