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The map label for this gene is pyrH

Identifier: 78778907

GI number: 78778907

Start: 488053

End: 488757

Strand: Reverse

Name: pyrH

Synonym: PMT9312_0522

Alternate gene names: 78778907

Gene position: 488757-488053 (Counterclockwise)

Preceding gene: 78778908

Following gene: 78778906

Centisome position: 28.6

GC content: 39.86

Gene sequence:

>705_bases
ATGACTTACAAAAGAGTTCTCTTAAAACTTAGTGGTGAAGCACTAATGGGTGAAAAACCTTATGGGATTGATCCTGCTAT
AGTTCAGTCAATTGCAGAAGACGTTTCAAAAGTAGTCGGAAATAATATTCAACTTGCAATAGTTGTTGGGGGTGGGAACA
TTTTTAGGGGACTTAAAGGCTCTGCAGATGGCATGGATAGAGCGACAGCTGATTATGTGGGCATGCTAGCAACAGTAATG
AATGCGATTTCACTTCAAGATGGTTTGGAAAGAGTAGGAGTAGCAACCAGAGTTCAAACTGCAATAGAAATGCAGGAAAT
TGCAGAGCCCTATATTAGAAGAAGGGCCATGAGGCACCTAGAAAAAGGTAGGGTTGTTGTTTTCGGAGGTGGGTGCGGAA
ATCCATTTTTCACAACTGACACGACGGCAGCTCTTAGGGCAGCAGAGATAAATGCTGAGGTTGTCATGAAAGCCACCAAA
GTTGATGGAGTATATAATTGTGATCCCAATAAATTTCAAGACGCAAAAAAATATACCAATCTCAGTTATCAACAAGTTCT
TAGTGATGAAATCGCAGTAATGGACAGTACTGCAATTGCGCTTTGCAAAGACAATAATATCCCTATTATGGTATTTGATA
TATTCAAAAAAGGGAACATCTCTAAAGCTGTCGCTGGGGAGGCTATAGGTTCATTAATTAGTTAA

Upstream 100 bases:

>100_bases
TTCAGATAGGTTTAGAAATGTTTAAAGACGCAAGCAATATCTGAACAAAAAATAAATTCGGTACATTTACTTGCTAAGGT
CTTAAAAGTATGATTATTGA

Downstream 100 bases:

>100_bases
AGCTTATTTAAATTTTTTTATTATGAAAGAACAAGAAATTCAAGAAAACATGAATAAAAGTATTGAAGCCACGCAAAGAA
ACTTTAATACTATAAGAACT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVGNNIQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVM
NAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATK
VDGVYNCDPNKFQDAKKYTNLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISKAVAGEAIGSLIS

Sequences:

>Translated_234_residues
MTYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVGNNIQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVM
NAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATK
VDGVYNCDPNKFQDAKKYTNLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISKAVAGEAIGSLIS
>Mature_233_residues
TYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVGNNIQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVMN
AISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKV
DGVYNCDPNKFQDAKKYTNLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISKAVAGEAIGSLIS

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=232, Percent_Identity=46.1206896551724, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25129; Mature: 24998

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVGNNIQLAIVVGGGNIFRGLKG
CCHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHCCCCC
SADGMDRATADYVGMLATVMNAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKVDGVYNCDPNKFQDAKKYTN
HCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHEEEEHHCCCEECCCCHHHHHHHHHCC
LSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISKAVAGEAIGSLIS
CHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVGNNIQLAIVVGGGNIFRGLKG
CHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHCCCCC
SADGMDRATADYVGMLATVMNAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKVDGVYNCDPNKFQDAKKYTN
HCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHEEEEHHCCCEECCCCHHHHHHHHHCC
LSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISKAVAGEAIGSLIS
CHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA