Click here to switch to the map view.

The map label for this gene is yrkA [H]

Identifier: 78778661

GI number: 78778661

Start: 263615

End: 264883

Strand: Reverse

Name: yrkA [H]

Synonym: PMT9312_0276

Alternate gene names: 78778661

Gene position: 264883-263615 (Counterclockwise)

Preceding gene: 78778664

Following gene: 78778660

Centisome position: 15.5

GC content: 32.47

Gene sequence:

>1269_bases
ATGAAAATAACTCTACTTTTATTTCTTTTATTTTTCCCAGCTTTTTTCGCAGCAAGTGAACTCTCTTTTTTGTTAATAAG
GCCAAGTAAAGTTTTAAGGCTAATAGAAGAAAAAAAGAAAGGAGCATTTTCAATTTTAAAAATTCAAAAACGATTTAGAT
CTTCCTTAATTGCTTCTCAATTTGGAGTAACAATTTCATTAATTGCAATTGGTTGGCTAAGTAATAGCATTGCAAATGAT
TATTGGAGAAGAAATATTTTGCCAAATAGGTTTTATGATCTTCTATTATTTTTGTTTGTGGTTTTAGTTGTTACACTTGT
CTCTGGACTAATTCCTAAAGCCCTAGTAATTAATAATCCAGAGTCTGCTGCATTAAGGTTAACCACCATATTCGACTCAG
TTAGAAAAGGTATGCAACCTGTTGTTGCGATAATAGAATTCTTTGCCAGCGCCTGTTTAGGTTTATTCAATTTAAATAAC
AAATGGGATTCTTTAAATTCGGGTTTATCTGCAGGTGAATTAGAAACTCTTATAGAAACAGATAATGTTACCGGTTTAAA
GCCAGATGAGAAGAATATTCTGGAAGGAGTTTTTGCTTTAAAAGACACACAGGTCAGAGAAGTAATGATTCCAAGATCTG
AAATGGTAACCTTGCCAAAAAATATAACTTTTTCAGAACTGATGAAACAAGTAGACAAGACTCGACATGCACGTTTTTTT
GTAATTGGCGAGTCTCTAGATGATGTATTAGGTGTATTAGATTTGCGTTATTTAGCTAAGCCAATATCAAAGAGTGAAAT
GGAAGCCGATACATTATTGGAGCCCTTCCTTTTACCAGTGACAAAAATAATAGAAACATGCTCATTAGCTGAAATATTGC
CAATAGTCAGAGACTATAATCCTTTTTTACTAGTGGTTGATGAACACGGTGGAACAGAGGGGCTCATAACTGCAGCTGAT
CTAAATGGCGAAATAGTTGGAGAGGAAATGCTTAATAATAGAACTTATTCAGATATGAAAATCTTAGATAATTTGTCTAA
AAAATGGTCAATAGCTGGAAAATCAGAAATTATAGATATCAACAAAAAGTTAGGATGTTCTATTCCAGAGGGTACAGACT
ACCATACCCTTGCTGGATTTCTGCTAGAAAAATTCCAAATGGTTCCAAAAATTGGAGATGTTTTAGATTTTAATAACATT
AAATTTGAAGTTATTTCTATGTCAGGTCCAAAAATTGATCGTGTTAAAATAATTCTTCCCAAAAGCTAA

Upstream 100 bases:

>100_bases
AACTCCCTTGGGGGTGTAGCAATCTGGTGAATGCACCAAACTCATAATTTGGCTAAGGCGAGTTCGATCCTCGCCACCCC
CATTATTTATTTGTCATTGA

Downstream 100 bases:

>100_bases
ATGGTGCTTCCAATAGAGGATAATAATACTTAAATATATGGATTTAAGTTATGCACCCAACCTCATCCCCCGTAAAGGTT
GGAGTCATAGGTATAGGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKITLLLFLLFFPAFFAASELSFLLIRPSKVLRLIEEKKKGAFSILKIQKRFRSSLIASQFGVTISLIAIGWLSNSIAND
YWRRNILPNRFYDLLLFLFVVLVVTLVSGLIPKALVINNPESAALRLTTIFDSVRKGMQPVVAIIEFFASACLGLFNLNN
KWDSLNSGLSAGELETLIETDNVTGLKPDEKNILEGVFALKDTQVREVMIPRSEMVTLPKNITFSELMKQVDKTRHARFF
VIGESLDDVLGVLDLRYLAKPISKSEMEADTLLEPFLLPVTKIIETCSLAEILPIVRDYNPFLLVVDEHGGTEGLITAAD
LNGEIVGEEMLNNRTYSDMKILDNLSKKWSIAGKSEIIDINKKLGCSIPEGTDYHTLAGFLLEKFQMVPKIGDVLDFNNI
KFEVISMSGPKIDRVKIILPKS

Sequences:

>Translated_422_residues
MKITLLLFLLFFPAFFAASELSFLLIRPSKVLRLIEEKKKGAFSILKIQKRFRSSLIASQFGVTISLIAIGWLSNSIAND
YWRRNILPNRFYDLLLFLFVVLVVTLVSGLIPKALVINNPESAALRLTTIFDSVRKGMQPVVAIIEFFASACLGLFNLNN
KWDSLNSGLSAGELETLIETDNVTGLKPDEKNILEGVFALKDTQVREVMIPRSEMVTLPKNITFSELMKQVDKTRHARFF
VIGESLDDVLGVLDLRYLAKPISKSEMEADTLLEPFLLPVTKIIETCSLAEILPIVRDYNPFLLVVDEHGGTEGLITAAD
LNGEIVGEEMLNNRTYSDMKILDNLSKKWSIAGKSEIIDINKKLGCSIPEGTDYHTLAGFLLEKFQMVPKIGDVLDFNNI
KFEVISMSGPKIDRVKIILPKS
>Mature_422_residues
MKITLLLFLLFFPAFFAASELSFLLIRPSKVLRLIEEKKKGAFSILKIQKRFRSSLIASQFGVTISLIAIGWLSNSIAND
YWRRNILPNRFYDLLLFLFVVLVVTLVSGLIPKALVINNPESAALRLTTIFDSVRKGMQPVVAIIEFFASACLGLFNLNN
KWDSLNSGLSAGELETLIETDNVTGLKPDEKNILEGVFALKDTQVREVMIPRSEMVTLPKNITFSELMKQVDKTRHARFF
VIGESLDDVLGVLDLRYLAKPISKSEMEADTLLEPFLLPVTKIIETCSLAEILPIVRDYNPFLLVVDEHGGTEGLITAAD
LNGEIVGEEMLNNRTYSDMKILDNLSKKWSIAGKSEIIDINKKLGCSIPEGTDYHTLAGFLLEKFQMVPKIGDVLDFNNI
KFEVISMSGPKIDRVKIILPKS

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=22.8947368421053, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1786879, Length=236, Percent_Identity=28.3898305084746, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790664, Length=435, Percent_Identity=23.2183908045977, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI145693175, Length=425, Percent_Identity=23.0588235294118, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082033, Length=259, Percent_Identity=25.0965250965251, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788119, Length=232, Percent_Identity=23.2758620689655, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47263; Mature: 47263

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITLLLFLLFFPAFFAASELSFLLIRPSKVLRLIEEKKKGAFSILKIQKRFRSSLIASQ
CHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FGVTISLIAIGWLSNSIANDYWRRNILPNRFYDLLLFLFVVLVVTLVSGLIPKALVINNP
HCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
ESAALRLTTIFDSVRKGMQPVVAIIEFFASACLGLFNLNNKWDSLNSGLSAGELETLIET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHCC
DNVTGLKPDEKNILEGVFALKDTQVREVMIPRSEMVTLPKNITFSELMKQVDKTRHARFF
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHEECCCCCCHHHHHHHHHHHHCCEEE
VIGESLDDVLGVLDLRYLAKPISKSEMEADTLLEPFLLPVTKIIETCSLAEILPIVRDYN
EECCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PFLLVVDEHGGTEGLITAADLNGEIVGEEMLNNRTYSDMKILDNLSKKWSIAGKSEIIDI
CEEEEEECCCCCCCEEEEECCCCCEECHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEC
NKKLGCSIPEGTDYHTLAGFLLEKFQMVPKIGDVLDFNNIKFEVISMSGPKIDRVKIILP
CHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEC
KS
CC
>Mature Secondary Structure
MKITLLLFLLFFPAFFAASELSFLLIRPSKVLRLIEEKKKGAFSILKIQKRFRSSLIASQ
CHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FGVTISLIAIGWLSNSIANDYWRRNILPNRFYDLLLFLFVVLVVTLVSGLIPKALVINNP
HCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
ESAALRLTTIFDSVRKGMQPVVAIIEFFASACLGLFNLNNKWDSLNSGLSAGELETLIET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHCC
DNVTGLKPDEKNILEGVFALKDTQVREVMIPRSEMVTLPKNITFSELMKQVDKTRHARFF
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHEECCCCCCHHHHHHHHHHHHCCEEE
VIGESLDDVLGVLDLRYLAKPISKSEMEADTLLEPFLLPVTKIIETCSLAEILPIVRDYN
EECCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PFLLVVDEHGGTEGLITAADLNGEIVGEEMLNNRTYSDMKILDNLSKKWSIAGKSEIIDI
CEEEEEECCCCCCCEEEEECCCCCEECHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEC
NKKLGCSIPEGTDYHTLAGFLLEKFQMVPKIGDVLDFNNIKFEVISMSGPKIDRVKIILP
CHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEC
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377; 8969508; 7608059 [H]