Click here to switch to the map view.

The map label for this gene is argS

Identifier: 78778575

GI number: 78778575

Start: 178789

End: 180603

Strand: Reverse

Name: argS

Synonym: PMT9312_0189

Alternate gene names: 78778575

Gene position: 180603-178789 (Counterclockwise)

Preceding gene: 78778576

Following gene: 78778574

Centisome position: 10.57

GC content: 28.82

Gene sequence:

>1815_bases
ATGCTAATCATTTTTAAAGAATTAACAAAACAATTTGAACAATCTCTTTTAGATAGTCTTGAAAAAAATGATAAAAGAGG
AGAATTCGACAATCTTAGAAAAAATTTAGTTACACAATCATCAAAAGAAGAGTTTGGTGATTATCAATGTAATGTTTGTC
TATGTTTATCTAAAATATATAAAAAGAAACCACGAGAAATCTCTGAAGATTTTGTTTATCTTTTAAATAAAAATAAAAGC
ATATCAAAATTATGCAAGAGTCTAGAAATAGCAGGACCTGGATTTATAAATATAAAATTAAAAGATGAAGTTCTAATAAA
TGAAATCAAATCAAATATTCAATGCCCTAGGGCTGGCATACCTCTAATTAAAAAAGATTTAGATAGTGGTTTGTCTAATA
AAGTGATTGTAGATTTTTCTAGTCCGAATATTGCTAAAGAAATGCATGTAGGGCATTTAAGATCAACAATAATAGGTGAC
TCAATATCTAGAATTTTCGAGTTAAGGGGTTATCAAGTATTAAGACTCAATCATGTTGGTGATTGGGGAACACAATTTGG
AATGCTTATTACTCAGCTCAAAGATTTATATTCAAATGATCTAGAAGAAATAGGAAAGATCAAGATAAGTGATTTAGTTG
AATTTTATAAAGCATCAAAAAAAAGATTTGATAATGAATCTGAATTCCAAAAAAGATCTAGGGAGGAAGTAGTCAAGTTA
CAAAGTGGAGATAGTAAATCTATCCAAGCCTGGAAATTGTTATGTGATCAATCGAGAAAGGAATTTGATGAAATCTATAA
AAATTTAAAAATCAAAATAAAAGAAAGAGGTGAATCTTTTTATAATCCATTTTTAAAGTCAGTTATTGAGGATTTGAAGT
TTAAAAAAATACTCATAGAAGATCAAGGAGCTAAATGTGTATTTTTAGATGGGATGACTAATAAAGAAGGCAAACCTTTA
CCGCTAATTGTTCAAAAAAAAGATGGCGGTTTTAATTATGCCACCACGGATCTTGCTGCCATAAGATACAGATTCAATAA
AGCGCCTAATGGGGATGATGCTTCAAGAATTATTTATGTAACTGATCATGGACAAGCAAATCATTTTGCTGGAGTTTTTC
AAGTTGCAAAAAAAGCAAAATGGATCCCAGATAAGTGTCAAGTAGACCATGTACCTTTTGGATTAGTTCAAGGAATTGAT
GGCAAAAAACTTAAGACAAGAGAAGGTGAAACAATACGTCTAAAAGATTTATTAAATGAAGCGGTTAGAAGAGCTAAAGA
AGATCTATTGAAAAGATTAGAAGATGAAGATCGTTACGAGACCGAAGAGTTTATTGCAAATACTTCAAGAATTATTGGAT
TAGGAGCTGTTAAGTATGCAGATTTAAGTCAAAATAGGATTACTAATTATCAATTTAGTTTTGATAAAATGCTTTCCCTT
AATGGAAATACTGCTCCTTATTTGCTATATACACTTGTAAGAATTTCAGGAATTAAAAGAAAAAATGATTTTGTTTATGA
CTCTGAAGATTTTCAGTACATAAATTATGAACATAAATCTGAGTGGAAACTTATCAGAAAATTACTTAAGTTCGATGAAG
TCATAATTTCTATTGAAAAAGACTTAATGCCAAATAGACTATGCAATTATCTGTTCGAGCTATGTCAAACTTTTAATAGA
TTCTATGATCAAGTTCCAATACTCAAAGAAGAAAAAAATATAAAAATTTCTAGACTTAATTTATGTGACCTAACTGCAAA
AACACTAAAATTAAGCTTAGAGCTTTTAGGAATTGAAACTTTAGAAAGAATGTAA

Upstream 100 bases:

>100_bases
TGATTTGATTTCAACAAGTTCTTCAATTACCAAAAGTAATTGGATTGATTTAAGTATGCGTTATATTAATTAATTATATA
GATAAATAATTGAATAATTA

Downstream 100 bases:

>100_bases
TGAATGATTTTGATCCATTAAATAATCTTTTCCCAAAACCAAGAGAAGAAATAATAAATATGCAGTCTTACTCTGCACCT
TTAGAAAATAGAAGAAATTT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MLIIFKELTKQFEQSLLDSLEKNDKRGEFDNLRKNLVTQSSKEEFGDYQCNVCLCLSKIYKKKPREISEDFVYLLNKNKS
ISKLCKSLEIAGPGFINIKLKDEVLINEIKSNIQCPRAGIPLIKKDLDSGLSNKVIVDFSSPNIAKEMHVGHLRSTIIGD
SISRIFELRGYQVLRLNHVGDWGTQFGMLITQLKDLYSNDLEEIGKIKISDLVEFYKASKKRFDNESEFQKRSREEVVKL
QSGDSKSIQAWKLLCDQSRKEFDEIYKNLKIKIKERGESFYNPFLKSVIEDLKFKKILIEDQGAKCVFLDGMTNKEGKPL
PLIVQKKDGGFNYATTDLAAIRYRFNKAPNGDDASRIIYVTDHGQANHFAGVFQVAKKAKWIPDKCQVDHVPFGLVQGID
GKKLKTREGETIRLKDLLNEAVRRAKEDLLKRLEDEDRYETEEFIANTSRIIGLGAVKYADLSQNRITNYQFSFDKMLSL
NGNTAPYLLYTLVRISGIKRKNDFVYDSEDFQYINYEHKSEWKLIRKLLKFDEVIISIEKDLMPNRLCNYLFELCQTFNR
FYDQVPILKEEKNIKISRLNLCDLTAKTLKLSLELLGIETLERM

Sequences:

>Translated_604_residues
MLIIFKELTKQFEQSLLDSLEKNDKRGEFDNLRKNLVTQSSKEEFGDYQCNVCLCLSKIYKKKPREISEDFVYLLNKNKS
ISKLCKSLEIAGPGFINIKLKDEVLINEIKSNIQCPRAGIPLIKKDLDSGLSNKVIVDFSSPNIAKEMHVGHLRSTIIGD
SISRIFELRGYQVLRLNHVGDWGTQFGMLITQLKDLYSNDLEEIGKIKISDLVEFYKASKKRFDNESEFQKRSREEVVKL
QSGDSKSIQAWKLLCDQSRKEFDEIYKNLKIKIKERGESFYNPFLKSVIEDLKFKKILIEDQGAKCVFLDGMTNKEGKPL
PLIVQKKDGGFNYATTDLAAIRYRFNKAPNGDDASRIIYVTDHGQANHFAGVFQVAKKAKWIPDKCQVDHVPFGLVQGID
GKKLKTREGETIRLKDLLNEAVRRAKEDLLKRLEDEDRYETEEFIANTSRIIGLGAVKYADLSQNRITNYQFSFDKMLSL
NGNTAPYLLYTLVRISGIKRKNDFVYDSEDFQYINYEHKSEWKLIRKLLKFDEVIISIEKDLMPNRLCNYLFELCQTFNR
FYDQVPILKEEKNIKISRLNLCDLTAKTLKLSLELLGIETLERM
>Mature_604_residues
MLIIFKELTKQFEQSLLDSLEKNDKRGEFDNLRKNLVTQSSKEEFGDYQCNVCLCLSKIYKKKPREISEDFVYLLNKNKS
ISKLCKSLEIAGPGFINIKLKDEVLINEIKSNIQCPRAGIPLIKKDLDSGLSNKVIVDFSSPNIAKEMHVGHLRSTIIGD
SISRIFELRGYQVLRLNHVGDWGTQFGMLITQLKDLYSNDLEEIGKIKISDLVEFYKASKKRFDNESEFQKRSREEVVKL
QSGDSKSIQAWKLLCDQSRKEFDEIYKNLKIKIKERGESFYNPFLKSVIEDLKFKKILIEDQGAKCVFLDGMTNKEGKPL
PLIVQKKDGGFNYATTDLAAIRYRFNKAPNGDDASRIIYVTDHGQANHFAGVFQVAKKAKWIPDKCQVDHVPFGLVQGID
GKKLKTREGETIRLKDLLNEAVRRAKEDLLKRLEDEDRYETEEFIANTSRIIGLGAVKYADLSQNRITNYQFSFDKMLSL
NGNTAPYLLYTLVRISGIKRKNDFVYDSEDFQYINYEHKSEWKLIRKLLKFDEVIISIEKDLMPNRLCNYLFELCQTFNR
FYDQVPILKEEKNIKISRLNLCDLTAKTLKLSLELLGIETLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=591, Percent_Identity=43.1472081218274, Blast_Score=446, Evalue=1e-125,
Organism=Homo sapiens, GI197100773, Length=587, Percent_Identity=31.8568994889268, Blast_Score=231, Evalue=1e-60,
Organism=Escherichia coli, GI1788184, Length=572, Percent_Identity=41.6083916083916, Blast_Score=454, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI71985061, Length=586, Percent_Identity=39.5904436860068, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71985068, Length=554, Percent_Identity=40.4332129963899, Blast_Score=377, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17532153, Length=506, Percent_Identity=26.6798418972332, Blast_Score=145, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6320548, Length=487, Percent_Identity=31.8275154004107, Blast_Score=213, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6321883, Length=569, Percent_Identity=28.6467486818981, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI18859963, Length=584, Percent_Identity=43.3219178082192, Blast_Score=439, Evalue=1e-123,
Organism=Drosophila melanogaster, GI28571570, Length=487, Percent_Identity=30.5954825462012, Blast_Score=195, Evalue=7e-50,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_PROM9 (Q31CZ4)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_396687.1
- ProteinModelPortal:   Q31CZ4
- SMR:   Q31CZ4
- STRING:   Q31CZ4
- GeneID:   3764974
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_0189
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- ProtClustDB:   PRK01611
- BioCyc:   PMAR74546:PMT9312_0189-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 69958; Mature: 69958

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIFKELTKQFEQSLLDSLEKNDKRGEFDNLRKNLVTQSSKEEFGDYQCNVCLCLSKIY
CEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHH
KKKPREISEDFVYLLNKNKSISKLCKSLEIAGPGFINIKLKDEVLINEIKSNIQCPRAGI
HCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCC
PLIKKDLDSGLSNKVIVDFSSPNIAKEMHVGHLRSTIIGDSISRIFELRGYQVLRLNHVG
CHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
DWGTQFGMLITQLKDLYSNDLEEIGKIKISDLVEFYKASKKRFDNESEFQKRSREEVVKL
CHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QSGDSKSIQAWKLLCDQSRKEFDEIYKNLKIKIKERGESFYNPFLKSVIEDLKFKKILIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHCCHHHHHHHHHHHHHHHHHEEEEE
DQGAKCVFLDGMTNKEGKPLPLIVQKKDGGFNYATTDLAAIRYRFNKAPNGDDASRIIYV
CCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
TDHGQANHFAGVFQVAKKAKWIPDKCQVDHVPFGLVQGIDGKKLKTREGETIRLKDLLNE
ECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCEECCCCCEEEHHHHHHH
AVRRAKEDLLKRLEDEDRYETEEFIANTSRIIGLGAVKYADLSQNRITNYQFSFDKMLSL
HHHHHHHHHHHHCCCCCCHHHHHHHHCCHHEEEECCEEECCCCCCCCCCEEECHHHHEEC
NGNTAPYLLYTLVRISGIKRKNDFVYDSEDFQYINYEHKSEWKLIRKLLKFDEVIISIEK
CCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
DLMPNRLCNYLFELCQTFNRFYDQVPILKEEKNIKISRLNLCDLTAKTLKLSLELLGIET
HCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
LERM
HHCC
>Mature Secondary Structure
MLIIFKELTKQFEQSLLDSLEKNDKRGEFDNLRKNLVTQSSKEEFGDYQCNVCLCLSKIY
CEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHH
KKKPREISEDFVYLLNKNKSISKLCKSLEIAGPGFINIKLKDEVLINEIKSNIQCPRAGI
HCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCC
PLIKKDLDSGLSNKVIVDFSSPNIAKEMHVGHLRSTIIGDSISRIFELRGYQVLRLNHVG
CHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
DWGTQFGMLITQLKDLYSNDLEEIGKIKISDLVEFYKASKKRFDNESEFQKRSREEVVKL
CHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QSGDSKSIQAWKLLCDQSRKEFDEIYKNLKIKIKERGESFYNPFLKSVIEDLKFKKILIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHCCHHHHHHHHHHHHHHHHHEEEEE
DQGAKCVFLDGMTNKEGKPLPLIVQKKDGGFNYATTDLAAIRYRFNKAPNGDDASRIIYV
CCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
TDHGQANHFAGVFQVAKKAKWIPDKCQVDHVPFGLVQGIDGKKLKTREGETIRLKDLLNE
ECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCEECCCCCEEEHHHHHHH
AVRRAKEDLLKRLEDEDRYETEEFIANTSRIIGLGAVKYADLSQNRITNYQFSFDKMLSL
HHHHHHHHHHHHCCCCCCHHHHHHHHCCHHEEEECCEEECCCCCCCCCCEEECHHHHEEC
NGNTAPYLLYTLVRISGIKRKNDFVYDSEDFQYINYEHKSEWKLIRKLLKFDEVIISIEK
CCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
DLMPNRLCNYLFELCQTFNRFYDQVPILKEEKNIKISRLNLCDLTAKTLKLSLELLGIET
HCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
LERM
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA