Click here to switch to the map view.

The map label for this gene is mraW

Identifier: 78778559

GI number: 78778559

Start: 165611

End: 166513

Strand: Reverse

Name: mraW

Synonym: PMT9312_0173

Alternate gene names: 78778559

Gene position: 166513-165611 (Counterclockwise)

Preceding gene: 78778562

Following gene: 78778557

Centisome position: 9.74

GC content: 32.34

Gene sequence:

>903_bases
ATGCAAACTGACCTATCTGATTCATCTTTTTTCAATCATAAATCAGTGATGACAGATGAAATTTTAGCCTCATTAGAGCA
TTACCCATTAATACATAACAACCAACTTAAAGGAATAGACGCAACTTTAGGCGGAGGCGGGCACTCTTATCATTTACTGA
GAAAATATTCGGATTTACATATAATTGGACTTGATCAAGATCCATTCGCAAGAAAATCAGCATCAAAAAAGCTTGATGAA
TTTAAAAATAGGATTGACATAAGGGCTGCAAATTTTGCGGATTTTGAACCAAAAGAAAAAGTTTCTTTTGTAATTGCAGA
TCTTGGAGTAAATAGTAACCAAATTGATGACCCTAAAAGAGGATTTAGTTTCCAAAAAGATGGTCCACTTGATATGCGCA
TGAATCCTTTTCTTGAGGTTGATGCAGAGAAATTAATTGAGACTTTACAAGAAAAAGATCTAGCTAACTTAATTTATAAA
TATGGAGATGAGAGATTATCAAGAAAGATTGCTAGGAAAATAAAAATGGATTTAAAGGTAAATGGGAAATATTCTGGGAC
AAAAGAGTTAGCTTATTCTATTGCAGGCTGCTTCCCACCAAAACAAAGATATAAAAAAATACACCCAGCAACTAGAACAT
TCCAAGCACTAAGAATTGCCGTTAATAAAGAAATTGAAGTATTAGAAAAATTTTTGCAAATTGTCCCTGATTGGCTATTG
CCAGGCGGAATTATTTCTATTATTAGTTTTCATTCCCTAGAGGATAGGTTAGTTAAAAGTTCTTTTAAGAATGATCAAAG
ATTAAAAAACCTGACAAAAAAGCCAATAACTCCCTCCGAACAAGAAGTAGAAATAAATAAAAGAGCTAGAAGTGGAAAAT
TAAGAGTTGCTCAATTAAATTAG

Upstream 100 bases:

>100_bases
GAGGGATGGTGAGGGCCAAAATTGACCACCATTGGTTCTGTTCTAGTCTCTAGCTGGGCCATTCGAAATTTAACTTCTAA
ATAAATCTTAGTCGAAAGTT

Downstream 100 bases:

>100_bases
TGAGCCAATAATTCCTAACGTAATGCTTTGATTGTATTAGTAAGTATTTGAATTGCTTGTTTTATATCTTTTGAACTAGT
GCTTAATCCAATACTTAGCC

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MQTDLSDSSFFNHKSVMTDEILASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLHIIGLDQDPFARKSASKKLDE
FKNRIDIRAANFADFEPKEKVSFVIADLGVNSNQIDDPKRGFSFQKDGPLDMRMNPFLEVDAEKLIETLQEKDLANLIYK
YGDERLSRKIARKIKMDLKVNGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQIVPDWLL
PGGIISIISFHSLEDRLVKSSFKNDQRLKNLTKKPITPSEQEVEINKRARSGKLRVAQLN

Sequences:

>Translated_300_residues
MQTDLSDSSFFNHKSVMTDEILASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLHIIGLDQDPFARKSASKKLDE
FKNRIDIRAANFADFEPKEKVSFVIADLGVNSNQIDDPKRGFSFQKDGPLDMRMNPFLEVDAEKLIETLQEKDLANLIYK
YGDERLSRKIARKIKMDLKVNGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQIVPDWLL
PGGIISIISFHSLEDRLVKSSFKNDQRLKNLTKKPITPSEQEVEINKRARSGKLRVAQLN
>Mature_300_residues
MQTDLSDSSFFNHKSVMTDEILASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLHIIGLDQDPFARKSASKKLDE
FKNRIDIRAANFADFEPKEKVSFVIADLGVNSNQIDDPKRGFSFQKDGPLDMRMNPFLEVDAEKLIETLQEKDLANLIYK
YGDERLSRKIARKIKMDLKVNGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQIVPDWLL
PGGIISIISFHSLEDRLVKSSFKNDQRLKNLTKKPITPSEQEVEINKRARSGKLRVAQLN

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=345, Percent_Identity=33.9130434782609, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI165377202, Length=176, Percent_Identity=35.7954545454545, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786270, Length=317, Percent_Identity=38.1703470031546, Blast_Score=179, Evalue=2e-46,
Organism=Drosophila melanogaster, GI62472493, Length=304, Percent_Identity=33.5526315789474, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571637, Length=304, Percent_Identity=33.5526315789474, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34243; Mature: 34243

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS01048 RIBOSOMAL_S6

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTDLSDSSFFNHKSVMTDEILASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLH
CCCCCCCCCHHCHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCCHHHHHHHCCCEE
IIGLDQDPFARKSASKKLDEFKNRIDIRAANFADFEPKEKVSFVIADLGVNSNQIDDPKR
EEECCCCCHHHHHHHHHHHHHHHHHCEEECCCCCCCCHHHHEEEEEECCCCCCCCCCHHH
GFSFQKDGPLDMRMNPFLEVDAEKLIETLQEKDLANLIYKYGDERLSRKIARKIKMDLKV
CCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
NGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQIVPDWLL
CCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
PGGIISIISFHSLEDRLVKSSFKNDQRLKNLTKKPITPSEQEVEINKRARSGKLRVAQLN
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MQTDLSDSSFFNHKSVMTDEILASLEHYPLIHNNQLKGIDATLGGGGHSYHLLRKYSDLH
CCCCCCCCCHHCHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCCHHHHHHHCCCEE
IIGLDQDPFARKSASKKLDEFKNRIDIRAANFADFEPKEKVSFVIADLGVNSNQIDDPKR
EEECCCCCHHHHHHHHHHHHHHHHHCEEECCCCCCCCHHHHEEEEEECCCCCCCCCCHHH
GFSFQKDGPLDMRMNPFLEVDAEKLIETLQEKDLANLIYKYGDERLSRKIARKIKMDLKV
CCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
NGKYSGTKELAYSIAGCFPPKQRYKKIHPATRTFQALRIAVNKEIEVLEKFLQIVPDWLL
CCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
PGGIISIISFHSLEDRLVKSSFKNDQRLKNLTKKPITPSEQEVEINKRARSGKLRVAQLN
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA