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The map label for this gene is dltR [H]

Identifier: 78778557

GI number: 78778557

Start: 163664

End: 164392

Strand: Reverse

Name: dltR [H]

Synonym: PMT9312_0171

Alternate gene names: 78778557

Gene position: 164392-163664 (Counterclockwise)

Preceding gene: 78778559

Following gene: 78778555

Centisome position: 9.62

GC content: 33.2

Gene sequence:

>729_bases
ATGAATGAAATTAATCAAATAAATAATGAAACAGTAAGAAAATCAAGAATTTTATTAGTTGATGATGAACCTGGTTTAAG
AACAGCTGTTAAAACATTTCTAGAAGATGAAGGGTTTGAAATATTTATTGCAGTTGATGGAGAGGACGGTTGGGAAAAAG
CTCAAACAATTTTTCCTGATTTGATTATTAGCGACGTTATGATGCCCCGAGCTAACGGTTATGCTTTATTAGAAAAAATT
AGAGAAGATGAAAAATTAGGAGGAACTCCAGTTATATTTTTAACCGCAAAAGGAATGACCTTAGACAGAACAGAGGGTTA
TCTTGCAGGAGTTGATGATTATATTTCCAAACCTTTCGACCCCGATGAATTAGCTGCGAGAGTTAAAAATGTAATCAATA
GACAAGAACGTTTACTAAAAGAAGCAGCACGATTCGCAGATATTGATGTAAGCAAAATGGCTAAGCAAATTACTGAAATA
AAATCTATGCTAACAGACCAAAATCCGACTAATTCAGAAAATAAAATAAATCTTCCTAGTTTTACTCCAAGAGAAGCAAG
TGTACTTCAACTAGTAGCAGAGGGGCTGATGAACAAGGAAATTGCAAGACAGCTTGAAACATCGATTAGAAATGTTGAAA
AATATGTAAGTAGACTTTTTATCAAGACAGGTACATCTAGCCGAACCGAATTAGTTCGTTATGCACTTGAAAATAATTTA
GTAAAATAA

Upstream 100 bases:

>100_bases
AGTTGATGATTGGTAGTCTAGTAGTATGGGAGTTGATAGCATTGTATTTAGTATATAAAATTCTCATTATTACTAGAAAC
CAAATTAAAGAATTTAAAAA

Downstream 100 bases:

>100_bases
ATTATTTATTTTTTTCGAATACAATTAGTTTTGAAAAATAAAAAGGAGCTTGATTTAATTTCGTTTTCACGACGTTAAAT
CCTTTTTCTTTAGCAGCATT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNEINQINNETVRKSRILLVDDEPGLRTAVKTFLEDEGFEIFIAVDGEDGWEKAQTIFPDLIISDVMMPRANGYALLEKI
REDEKLGGTPVIFLTAKGMTLDRTEGYLAGVDDYISKPFDPDELAARVKNVINRQERLLKEAARFADIDVSKMAKQITEI
KSMLTDQNPTNSENKINLPSFTPREASVLQLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENNL
VK

Sequences:

>Translated_242_residues
MNEINQINNETVRKSRILLVDDEPGLRTAVKTFLEDEGFEIFIAVDGEDGWEKAQTIFPDLIISDVMMPRANGYALLEKI
REDEKLGGTPVIFLTAKGMTLDRTEGYLAGVDDYISKPFDPDELAARVKNVINRQERLLKEAARFADIDVSKMAKQITEI
KSMLTDQNPTNSENKINLPSFTPREASVLQLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENNL
VK
>Mature_242_residues
MNEINQINNETVRKSRILLVDDEPGLRTAVKTFLEDEGFEIFIAVDGEDGWEKAQTIFPDLIISDVMMPRANGYALLEKI
REDEKLGGTPVIFLTAKGMTLDRTEGYLAGVDDYISKPFDPDELAARVKNVINRQERLLKEAARFADIDVSKMAKQITEI
KSMLTDQNPTNSENKINLPSFTPREASVLQLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENNL
VK

Specific function: Member of the two-component regulatory system dltS/dltR. Regulates the expression of the dlt operon [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=39.4957983193277, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367329, Length=122, Percent_Identity=42.6229508196721, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786784, Length=151, Percent_Identity=33.112582781457, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790860, Length=155, Percent_Identity=30.3225806451613, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790863, Length=119, Percent_Identity=35.2941176470588, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=35, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786911, Length=143, Percent_Identity=34.965034965035, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788394, Length=119, Percent_Identity=35.2941176470588, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=35.5371900826446, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787229, Length=120, Percent_Identity=32.5, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787473, Length=217, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87082012, Length=123, Percent_Identity=35.7723577235772, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=31.0924369747899, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789402, Length=119, Percent_Identity=34.453781512605, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=125, Percent_Identity=29.6, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788222, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=103, Percent_Identity=35.9223300970874, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788712, Length=224, Percent_Identity=24.5535714285714, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27372; Mature: 27372

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEINQINNETVRKSRILLVDDEPGLRTAVKTFLEDEGFEIFIAVDGEDGWEKAQTIFPD
CCCHHHHCHHHHHHCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
LIISDVMMPRANGYALLEKIREDEKLGGTPVIFLTAKGMTLDRTEGYLAGVDDYISKPFD
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCCCCCCHHHHCCCCC
PDELAARVKNVINRQERLLKEAARFADIDVSKMAKQITEIKSMLTDQNPTNSENKINLPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCC
FTPREASVLQLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENNL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
VK
CC
>Mature Secondary Structure
MNEINQINNETVRKSRILLVDDEPGLRTAVKTFLEDEGFEIFIAVDGEDGWEKAQTIFPD
CCCHHHHCHHHHHHCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
LIISDVMMPRANGYALLEKIREDEKLGGTPVIFLTAKGMTLDRTEGYLAGVDDYISKPFD
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCCCCCCHHHHCCCCC
PDELAARVKNVINRQERLLKEAARFADIDVSKMAKQITEIKSMLTDQNPTNSENKINLPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCC
FTPREASVLQLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENNL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11591677; 12354221 [H]