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The map label for this gene is yitJ [H]

Identifier: 78778541

GI number: 78778541

Start: 151160

End: 152050

Strand: Reverse

Name: yitJ [H]

Synonym: PMT9312_0155

Alternate gene names: 78778541

Gene position: 152050-151160 (Counterclockwise)

Preceding gene: 78778543

Following gene: 78778535

Centisome position: 8.9

GC content: 35.58

Gene sequence:

>891_bases
TTGAAATCAAAACTTCAGCAGACTTTAGAAAAAAAATCCAAGGTGATAACAGCAGAGTTAATGCCGCCCAGAGGTGGAAA
CCCCATAAGATCTCTTAAGATAGCACAACTTTTGAAAGATAAGGTACATGCTGTTAACATTACCGACGGGAGCAGAGCTG
TAATGAGAATGTGCAGCTTGGCAATGTCCAAACTATTACTGGAAAATGGAATAGAACCAGTAATGCAGATATCTTGCAGA
GATCGTAATAAAATTGCTTTACAATCAGACATTTTGGGAGCAAATGCTTTAGGAATTAGAAACATTTTATGCATTACCGG
TGATTCAGTAAAAGCCGGGGATCAACAAGATGCTAAAGCAGTACATGAGTTTGAGTCAGTTAGATTACTTCAACAAATTC
AGTCCTTCAATAAAGGAATAGATCCTACTCTAGGAAAACTTTCCGATAAAAAAACATTTATTTTTTCAGGGGCTGCAGCT
GATCCTAGTTGCAGAAATCAAAGAAGTTTAGAAAATAGAATGAAAAAGAAAAAAGAGGCCGGAGCTGGATTCGTACAAAC
TCAAATGGTTATGAAAAAAGAAAATTTGATAGAATTTTGTGAAAAAATTAGCAACCCTCTTGAAATTCCTGTAATTGCAG
GGGTATTCCTTTTAAAGTCTTACAAAAACGCTCTCTTTATAAACAAATATGTCCCTGGTGCAAATATACCTGAAAAAATC
TTAAATCGTCTTAAAGATGCTAAAGACCCTTTACAGGAAGGTATTAACATTGCCGCTGAGCAAGCTCATGATTTTATTAA
CATCGCAAATGGTATTCATCTAATGGCAGTGAAGGCAGAGCATTTAATACCTAAGATCCTTGAAAAAGCTGATCTTACTC
TGGAATATTAA

Upstream 100 bases:

>100_bases
ACTTCTTCTTCAACCATTTGCATTTAAACAGTTCCTTTTTTATATTAGATAAGTTTAGCAATCTCAGTACACTTGTTAAC
TAAGTAGGAAACAAAAGCAA

Downstream 100 bases:

>100_bases
TCAAATCAGTACCTAACAATTCCGCCATTGCCTTCTGCTGTGGAGATGGCTCGGTCATGTCAGATCTTCTTGAATCTGTT
ATCAACCAATCCAAAGATGC

Product: methylenetetrahydrofolate reductase

Products: NA

Alternate protein names: Homocysteine S-methyltransferase; S-methylmethionine:homocysteine methyltransferase; 5,10-methylenetetrahydrofolate reductase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKSKLQQTLEKKSKVITAELMPPRGGNPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSLAMSKLLLENGIEPVMQISCR
DRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKAVHEFESVRLLQQIQSFNKGIDPTLGKLSDKKTFIFSGAAA
DPSCRNQRSLENRMKKKKEAGAGFVQTQMVMKKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPEKI
LNRLKDAKDPLQEGINIAAEQAHDFINIANGIHLMAVKAEHLIPKILEKADLTLEY

Sequences:

>Translated_296_residues
MKSKLQQTLEKKSKVITAELMPPRGGNPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSLAMSKLLLENGIEPVMQISCR
DRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKAVHEFESVRLLQQIQSFNKGIDPTLGKLSDKKTFIFSGAAA
DPSCRNQRSLENRMKKKKEAGAGFVQTQMVMKKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPEKI
LNRLKDAKDPLQEGINIAAEQAHDFINIANGIHLMAVKAEHLIPKILEKADLTLEY
>Mature_296_residues
MKSKLQQTLEKKSKVITAELMPPRGGNPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSLAMSKLLLENGIEPVMQISCR
DRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKAVHEFESVRLLQQIQSFNKGIDPTLGKLSDKKTFIFSGAAA
DPSCRNQRSLENRMKKKKEAGAGFVQTQMVMKKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPEKI
LNRLKDAKDPLQEGINIAAEQAHDFINIANGIHLMAVKAEHLIPKILEKADLTLEY

Specific function: Unknown

COG id: COG0685

COG function: function code E; 5,10-methylenetetrahydrofolate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Hcy-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003171
- InterPro:   IPR003726 [H]

Pfam domain/function: PF02219 MTHFR; PF02574 S-methyl_trans [H]

EC number: =2.1.1.10; =1.5.1.20 [H]

Molecular weight: Translated: 32754; Mature: 32754

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKLQQTLEKKSKVITAELMPPRGGNPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
CCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHH
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKA
HHHHHHHHHCCCHHHHHHCCCCCCEEHHHHCCCCCCHHHCEEEEEECCCCCCCCHHHHHH
VHEFESVRLLQQIQSFNKGIDPTLGKLSDKKTFIFSGAAADPSCRNQRSLENRMKKKKEA
HHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
GAGFVQTQMVMKKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPEKI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHH
LNRLKDAKDPLQEGINIAAEQAHDFINIANGIHLMAVKAEHLIPKILEKADLTLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MKSKLQQTLEKKSKVITAELMPPRGGNPIRSLKIAQLLKDKVHAVNITDGSRAVMRMCSL
CCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHH
AMSKLLLENGIEPVMQISCRDRNKIALQSDILGANALGIRNILCITGDSVKAGDQQDAKA
HHHHHHHHHCCCHHHHHHCCCCCCEEHHHHCCCCCCHHHCEEEEEECCCCCCCCHHHHHH
VHEFESVRLLQQIQSFNKGIDPTLGKLSDKKTFIFSGAAADPSCRNQRSLENRMKKKKEA
HHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
GAGFVQTQMVMKKENLIEFCEKISNPLEIPVIAGVFLLKSYKNALFINKYVPGANIPEKI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHH
LNRLKDAKDPLQEGINIAAEQAHDFINIANGIHLMAVKAEHLIPKILEKADLTLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]