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The map label for this gene is ndhD [H]

Identifier: 78778538

GI number: 78778538

Start: 147400

End: 149004

Strand: Direct

Name: ndhD [H]

Synonym: PMT9312_0152

Alternate gene names: 78778538

Gene position: 147400-149004 (Clockwise)

Preceding gene: 78778537

Following gene: 78778539

Centisome position: 8.62

GC content: 34.89

Gene sequence:

>1605_bases
ATGTTGGGAACTTTGGGATCTGGATTCTCTAATTTTCCTTGGCTATCTGCCTCAATTTTGTTTCCAATTGGTAGTGCATT
TGTTATACCTTTTTTCCCAGATAAAGGCGATGGGAAAGAGGTTAGATGGTTTGCATTATCTATTGCATTAACAACTTTTT
TAATAACTGTAGGTTCATACATAAATGGCTTTGATATTAATAATGAAAATGTTCAACTGAAAGAAAATGTTAGTTGGCTC
CCTGATTTAGGTCTTACTTGGTCTGTTGGTGCTGATGGTATTTCGATGCCGTTAATATTATTAACTAGTTTTATAACTGC
TTTAGCAGTTCTAGCTGCATGGCCTGTCAAGTTCAAGCCAAAGTTATTTTTCTTTTTGATATTGGTCATGGATGGTGGGC
AAATCGCTGTATTCGCAGTTCAAGATATGCTTTTATTCTTTCTAACTTGGGAACTTGAGTTAATTCCCGTTTATTTACTA
TTGGCTATATGGGGTGGCAAAAATAGACAATATGCAGCAACAAAATTCATTATTTATACAGCTGGAAGTTCTATATTTAT
CCTACTAGCAGCATTGGCAATGGGTTTCTACGGAACAGAAATTCCTAACTTTGAGTTTTCGCACTTGGCAGCTCAAGATT
TTACTCAAAAATTCCAAATTCTTTGTTACGTTGGGCTTTTAATTGCATTTGGAGTAAAGCTACCAATAGTGCCTCTTCAT
ACTTGGCTTCCAGACGCTCATGGAGAGGCTACAGCTCCTGTTCATATGCTGCTAGCTGGAATTTTATTAAAAATGGGAGG
ATATGCTCTTTTAAGATTTAATGCTCAATTATTACCCGCTGCTCATGCACAATTTGCTCCATTATTAATAGTTTTGGGAG
TAGTAAATATAATTTATGCTGCATTAACTTCTTTTGCACAAAGAAATCTCAAAAGAAAAATTGCATACAGTTCTATAAGT
CATATGGGTTTTGTTCTTATTGGAATAGGCAGTTTTAGTAGTCTTGGAACAAGCGGAGCAATGCTACAAATGGTTAGTCA
TGGATTAATTGGAGCTAGTTTATTTTTTCTTGTTGGAGCAACCTATGACAGAACAAAGACTCTTAAACTTGATGAAATGA
GTGGTGTAGGACAAAAAATGAGAATAATGTTTGCCTTATGGACTGCTTGCTCCCTTGCTTCACTTGCTTTGCCAGGTATG
AGTGGATTTGTTTCCGAATTAATGGTATTCACAGGATTTGTTACCGATGAAGTTTATACACTTCCGTTTAGGGTGATTAT
GGCCTCTTTAGCTGCTATAGGTGTAATACTTACTCCTATTTATCTACTTTCAATGTTACGAGAAATTTTCTTTGGTAAAG
AAAATCCTAAATTAACCGAAGAACGTAAACTTATCGATGCAGAGCCCAGGGAAGTTTATATTATTGCTTGTTTACTTTTG
CCGATAATTGGAATAGGTCTATACCCAAGATTAGTTACTGAAAGTTATCTTGCATCTATTAATAATTTAGTTGATAGAGA
TTTAACTGCTGTTAAAAGTGCTGTGAAAACAAATATTTTTTCAGGAACAAAAAAAAATGAGATCCTAAAAGCTCCAACAA
TATAA

Upstream 100 bases:

>100_bases
GTCCATTGGGATGAAAAAATACAGATAATTTCTAGACTTTATTTAAGAGAAACTTCTTATTAAATTGAGTAATTATTATT
TTACAAATTTTGCGACACAA

Downstream 100 bases:

>100_bases
TTTTTTAAATTAATTCAATATTGTTTGGCATTAAATAATTAAGGAGATATCTTATGGGTAGATATTTAAAATTTTAAAAT
ACCTTATTTCAATTCCATTG

Product: NAD(P)H-quinone oxidoreductase subunit 4

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I, chain 4; NDH-1, chain 4 [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MLGTLGSGFSNFPWLSASILFPIGSAFVIPFFPDKGDGKEVRWFALSIALTTFLITVGSYINGFDINNENVQLKENVSWL
PDLGLTWSVGADGISMPLILLTSFITALAVLAAWPVKFKPKLFFFLILVMDGGQIAVFAVQDMLLFFLTWELELIPVYLL
LAIWGGKNRQYAATKFIIYTAGSSIFILLAALAMGFYGTEIPNFEFSHLAAQDFTQKFQILCYVGLLIAFGVKLPIVPLH
TWLPDAHGEATAPVHMLLAGILLKMGGYALLRFNAQLLPAAHAQFAPLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSIS
HMGFVLIGIGSFSSLGTSGAMLQMVSHGLIGASLFFLVGATYDRTKTLKLDEMSGVGQKMRIMFALWTACSLASLALPGM
SGFVSELMVFTGFVTDEVYTLPFRVIMASLAAIGVILTPIYLLSMLREIFFGKENPKLTEERKLIDAEPREVYIIACLLL
PIIGIGLYPRLVTESYLASINNLVDRDLTAVKSAVKTNIFSGTKKNEILKAPTI

Sequences:

>Translated_534_residues
MLGTLGSGFSNFPWLSASILFPIGSAFVIPFFPDKGDGKEVRWFALSIALTTFLITVGSYINGFDINNENVQLKENVSWL
PDLGLTWSVGADGISMPLILLTSFITALAVLAAWPVKFKPKLFFFLILVMDGGQIAVFAVQDMLLFFLTWELELIPVYLL
LAIWGGKNRQYAATKFIIYTAGSSIFILLAALAMGFYGTEIPNFEFSHLAAQDFTQKFQILCYVGLLIAFGVKLPIVPLH
TWLPDAHGEATAPVHMLLAGILLKMGGYALLRFNAQLLPAAHAQFAPLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSIS
HMGFVLIGIGSFSSLGTSGAMLQMVSHGLIGASLFFLVGATYDRTKTLKLDEMSGVGQKMRIMFALWTACSLASLALPGM
SGFVSELMVFTGFVTDEVYTLPFRVIMASLAAIGVILTPIYLLSMLREIFFGKENPKLTEERKLIDAEPREVYIIACLLL
PIIGIGLYPRLVTESYLASINNLVDRDLTAVKSAVKTNIFSGTKKNEILKAPTI
>Mature_534_residues
MLGTLGSGFSNFPWLSASILFPIGSAFVIPFFPDKGDGKEVRWFALSIALTTFLITVGSYINGFDINNENVQLKENVSWL
PDLGLTWSVGADGISMPLILLTSFITALAVLAAWPVKFKPKLFFFLILVMDGGQIAVFAVQDMLLFFLTWELELIPVYLL
LAIWGGKNRQYAATKFIIYTAGSSIFILLAALAMGFYGTEIPNFEFSHLAAQDFTQKFQILCYVGLLIAFGVKLPIVPLH
TWLPDAHGEATAPVHMLLAGILLKMGGYALLRFNAQLLPAAHAQFAPLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSIS
HMGFVLIGIGSFSSLGTSGAMLQMVSHGLIGASLFFLVGATYDRTKTLKLDEMSGVGQKMRIMFALWTACSLASLALPGM
SGFVSELMVFTGFVTDEVYTLPFRVIMASLAAIGVILTPIYLLSMLREIFFGKENPKLTEERKLIDAEPREVYIIACLLL
PIIGIGLYPRLVTESYLASINNLVDRDLTAVKSAVKTNIFSGTKKNEILKAPTI

Specific function: NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton tran

COG id: COG1008

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 4 (chain M)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family [H]

Homologues:

Organism=Homo sapiens, GI251831116, Length=378, Percent_Identity=29.8941798941799, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1788613, Length=517, Percent_Identity=36.7504835589942, Blast_Score=294, Evalue=1e-80,
Organism=Escherichia coli, GI1788831, Length=268, Percent_Identity=30.9701492537313, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788827, Length=300, Percent_Identity=23, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI2367154, Length=203, Percent_Identity=27.0935960591133, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788614, Length=450, Percent_Identity=23.5555555555556, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI145693160, Length=384, Percent_Identity=25, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788829, Length=479, Percent_Identity=24.8434237995825, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022997
- InterPro:   IPR010227
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: 1.6.5.3

Molecular weight: Translated: 58410; Mature: 58410

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS01095 CHITINASE_18

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGTLGSGFSNFPWLSASILFPIGSAFVIPFFPDKGDGKEVRWFALSIALTTFLITVGSY
CCCCCCCCCCCCCCHHHHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
INGFDINNENVQLKENVSWLPDLGLTWSVGADGISMPLILLTSFITALAVLAAWPVKFKP
HCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
KLFFFLILVMDGGQIAVFAVQDMLLFFLTWELELIPVYLLLAIWGGKNRQYAATKFIIYT
HHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEE
AGSSIFILLAALAMGFYGTEIPNFEFSHLAAQDFTQKFQILCYVGLLIAFGVKLPIVPLH
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
TWLPDAHGEATAPVHMLLAGILLKMGGYALLRFNAQLLPAAHAQFAPLLIVLGVVNIIYA
HHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHH
ALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFSSLGTSGAMLQMVSHGLIGASLFFLVGA
HHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHCC
TYDRTKTLKLDEMSGVGQKMRIMFALWTACSLASLALPGMSGFVSELMVFTGFVTDEVYT
CCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHH
LPFRVIMASLAAIGVILTPIYLLSMLREIFFGKENPKLTEERKLIDAEPREVYIIACLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEHHHHHHH
PIIGIGLYPRLVTESYLASINNLVDRDLTAVKSAVKTNIFSGTKKNEILKAPTI
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLGTLGSGFSNFPWLSASILFPIGSAFVIPFFPDKGDGKEVRWFALSIALTTFLITVGSY
CCCCCCCCCCCCCCHHHHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
INGFDINNENVQLKENVSWLPDLGLTWSVGADGISMPLILLTSFITALAVLAAWPVKFKP
HCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
KLFFFLILVMDGGQIAVFAVQDMLLFFLTWELELIPVYLLLAIWGGKNRQYAATKFIIYT
HHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEE
AGSSIFILLAALAMGFYGTEIPNFEFSHLAAQDFTQKFQILCYVGLLIAFGVKLPIVPLH
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
TWLPDAHGEATAPVHMLLAGILLKMGGYALLRFNAQLLPAAHAQFAPLLIVLGVVNIIYA
HHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHH
ALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFSSLGTSGAMLQMVSHGLIGASLFFLVGA
HHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHCC
TYDRTKTLKLDEMSGVGQKMRIMFALWTACSLASLALPGMSGFVSELMVFTGFVTDEVYT
CCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHH
LPFRVIMASLAAIGVILTPIYLLSMLREIFFGKENPKLTEERKLIDAEPREVYIIACLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEHHHHHHH
PIIGIGLYPRLVTESYLASINNLVDRDLTAVKSAVKTNIFSGTKKNEILKAPTI
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA