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The map label for this gene is synA [H]

Identifier: 78778519

GI number: 78778519

Start: 128253

End: 130559

Strand: Reverse

Name: synA [H]

Synonym: PMT9312_0133

Alternate gene names: 78778519

Gene position: 130559-128253 (Counterclockwise)

Preceding gene: 78778521

Following gene: 78778518

Centisome position: 7.64

GC content: 31.6

Gene sequence:

>2307_bases
GTGATAAGAAAGGAGAGCATTCAATTAAGCATTACAGGAATGAAGTGCGGTGGTTGCGTTAGTACTGTTGAAACAATATT
AAATAATTCTGATGGTATTGAAAATGTTTCTGTTAACTTACTCACTGAAAGTGCATATTTTGAAATTAGCTATAAACATA
TAGAAATAGAAACAGTTCTCGAAAAACTTAAAGAGAATGGTTTCCCATCAAAGATTTACATAAATGATTTTTCAAAAAAA
ATAAATAAAGAAGAATTATCAAAAAAAAAGAAATGGAATAATCAATGGCAAAAGCTAACTTTTGCTCTATTACTTTTACT
ATTTTCAGGTTTAGGTCATCTGGCAGAAGGAAAATATATAAATTTTCCAATATTAGGTAATATATTTTTTCATGCCTCAT
TAGCAACAATAGCTTTATTATTTCCAGGAAGAAGAATAATTATTAATGGATTTAAATCATTTATAAAGAATCGTCCGGAT
ATGGATTCTTTAGTAGCTCTTGGAGTAACTAGCGCTTATATAACAAGTCTTCTATCCTTAATATTCCCTGCTAGTGGTTT
TCCTTGTTTTTTTAATGAACCAGTTATGCTTTTAGGTTTTATATTGATTGGGCGTTTCTTAGAAGAAAGAGCTAGATATC
AAACTGGTTCATCAATTGGAGAGTTATTAGATCTTCAACCTGAAATGGCAAATATCTACACAAAAGATAATCAAATAAAG
TCAATAAGAGTCAATGCTTTAAAGCCTGATCAAGAGATTCAAATTTTAGCAGGTGACAGAGTCCCTGCTGACTGCATTGT
TACTCAGGGTAATTCATATGTTGATGTTTCACATATTACTGGAGAATCCAAACCTATCGAAGTAAAAGAAGGTGAAAAGT
TATCCAGTGGGTCTTTAAATCTTAATTCAACTCTTAGACTAAAAGTACAGAAGGTCGGCGGGGATTCTTCTCTTGCACAA
CTAGTAAGTCTTATTGAGTCTGTAAACGCTAATAAACCTCCAATTCAAAGAATTGCTGACAAAATTGCAGGAAAATTTAC
TTACTTTGTACTTATATTTGCCACTTTAAGTTTCTTTTTTTGGTGGAAGGGGGCAAAACACATTTGGCCTGATTTATTAA
GTCACAATCATCATCAATTATTAACAAATTCAAGCCACACACTTCATAGTTCTCTTGGTAGTAATGCTGAGAATTTCCTG
AGTTTAGCAATTCAATTGTCAATTGCTGTTTTAGTAATAGCTTGTCCTTGTGCATTAGGTTTAGCCACACCAACAGTAAT
CACTGTCGCATCAGGTAAAGCCGCAAAAAAAGGGGTTTTATTCAAAGGAGGTGACAAAATAGAGATGGCTTCAAAAATTA
ATCATATTATTTTTGATAAGACTGGTACATTAACAAAAGGTAAGCTTTTCATCGTTGATTATAAAAATAATAACGATCAT
ACATACTTATTAAGAATTGCTGCCAGTTTAGAAAAGGAAAGCAGACATCCAATCGCAAATGCCTTAATTCAAGAGGCCCA
AAAACAAAATTTAAGTTTATTTCCAATAAAAAAAATATTAACTCATTCAGGGAGAGGTATATCTGGAGAACTTGAGTCAG
TTGAAGGACTGATCAATATTGGAAATATTGAATGGCTACTAAGCAAAGGGATAGTTATTGATAATAATGCAAAAAAAGTC
ATTGAAAATGAAGAAACACAAACGCATACAATTATTGGAGTCAGTATAAAAGATAAGTTACTAGGATTTATCTTATTAGG
AGATTTACTCAGAGAGGATTCAATAAAAACAGTTCAAAATTTGAGACAAAACAAATTTAAAATTAATATTTTAAGTGGAG
ATAGAAAACAAACAGTTTTAGCTTTAGCAAAAAAAATTGGTTTTAAAGAAACGGAAGTAAAATGGAACCTTCTTCCTCAT
ATGAAACTTAAAACTATAGAAAATTTAAAAATCGATAATAAAGTGGCTATGGTTGGTGATGGAATTAATGATGTCCCAGC
CTTAGCATCCTCTGACTTAGGAATTGCAGTAGGATCAGGAACTCAAATAGCGAAGGCAAATGCAGATATAGTATTAATGG
GAGATCAACTTAATGGATTACCATACTCATTAAATCTTGCAAAAAAAACTATGAGAAAAATAAAGCAGAATCTAATATGG
GCTTTTGGTTACAACTTACTAGCGATCCCAATAGCCGCAGGTATTTTGTTTCCTAAATATGACATTCTTCTTACTCCCTC
AATAGCAGCATTATTAATGGCTACAAGCTCTATTACAGTTGTCATTAATGCTTTATCTTTGGATTAA

Upstream 100 bases:

>100_bases
TCAATAAAATTATTATAGTAATTTAAAATAACTATTTAAAAAGTCTATTACATTTTTTATTATAATTACAAATGAAACCA
AGAATTAATTTGCTTCTATT

Downstream 100 bases:

>100_bases
ATGAAAGGCAAATTTATTGTTATTGAAGGTATTGATGGATGTGGTAAGACTACCCAAATAAATGAACTATCTAAATGGCT
TCCTAAAAGTGGTCTAATAA

Product: putative P-type ATPase transporter for copper

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 768; Mature: 768

Protein sequence:

>768_residues
MIRKESIQLSITGMKCGGCVSTVETILNNSDGIENVSVNLLTESAYFEISYKHIEIETVLEKLKENGFPSKIYINDFSKK
INKEELSKKKKWNNQWQKLTFALLLLLFSGLGHLAEGKYINFPILGNIFFHASLATIALLFPGRRIIINGFKSFIKNRPD
MDSLVALGVTSAYITSLLSLIFPASGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTKDNQIK
SIRVNALKPDQEIQILAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEKLSSGSLNLNSTLRLKVQKVGGDSSLAQ
LVSLIESVNANKPPIQRIADKIAGKFTYFVLIFATLSFFFWWKGAKHIWPDLLSHNHHQLLTNSSHTLHSSLGSNAENFL
SLAIQLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKLFIVDYKNNNDH
TYLLRIAASLEKESRHPIANALIQEAQKQNLSLFPIKKILTHSGRGISGELESVEGLINIGNIEWLLSKGIVIDNNAKKV
IENEETQTHTIIGVSIKDKLLGFILLGDLLREDSIKTVQNLRQNKFKINILSGDRKQTVLALAKKIGFKETEVKWNLLPH
MKLKTIENLKIDNKVAMVGDGINDVPALASSDLGIAVGSGTQIAKANADIVLMGDQLNGLPYSLNLAKKTMRKIKQNLIW
AFGYNLLAIPIAAGILFPKYDILLTPSIAALLMATSSITVVINALSLD

Sequences:

>Translated_768_residues
MIRKESIQLSITGMKCGGCVSTVETILNNSDGIENVSVNLLTESAYFEISYKHIEIETVLEKLKENGFPSKIYINDFSKK
INKEELSKKKKWNNQWQKLTFALLLLLFSGLGHLAEGKYINFPILGNIFFHASLATIALLFPGRRIIINGFKSFIKNRPD
MDSLVALGVTSAYITSLLSLIFPASGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTKDNQIK
SIRVNALKPDQEIQILAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEKLSSGSLNLNSTLRLKVQKVGGDSSLAQ
LVSLIESVNANKPPIQRIADKIAGKFTYFVLIFATLSFFFWWKGAKHIWPDLLSHNHHQLLTNSSHTLHSSLGSNAENFL
SLAIQLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKLFIVDYKNNNDH
TYLLRIAASLEKESRHPIANALIQEAQKQNLSLFPIKKILTHSGRGISGELESVEGLINIGNIEWLLSKGIVIDNNAKKV
IENEETQTHTIIGVSIKDKLLGFILLGDLLREDSIKTVQNLRQNKFKINILSGDRKQTVLALAKKIGFKETEVKWNLLPH
MKLKTIENLKIDNKVAMVGDGINDVPALASSDLGIAVGSGTQIAKANADIVLMGDQLNGLPYSLNLAKKTMRKIKQNLIW
AFGYNLLAIPIAAGILFPKYDILLTPSIAALLMATSSITVVINALSLD
>Mature_768_residues
MIRKESIQLSITGMKCGGCVSTVETILNNSDGIENVSVNLLTESAYFEISYKHIEIETVLEKLKENGFPSKIYINDFSKK
INKEELSKKKKWNNQWQKLTFALLLLLFSGLGHLAEGKYINFPILGNIFFHASLATIALLFPGRRIIINGFKSFIKNRPD
MDSLVALGVTSAYITSLLSLIFPASGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTKDNQIK
SIRVNALKPDQEIQILAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEKLSSGSLNLNSTLRLKVQKVGGDSSLAQ
LVSLIESVNANKPPIQRIADKIAGKFTYFVLIFATLSFFFWWKGAKHIWPDLLSHNHHQLLTNSSHTLHSSLGSNAENFL
SLAIQLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKLFIVDYKNNNDH
TYLLRIAASLEKESRHPIANALIQEAQKQNLSLFPIKKILTHSGRGISGELESVEGLINIGNIEWLLSKGIVIDNNAKKV
IENEETQTHTIIGVSIKDKLLGFILLGDLLREDSIKTVQNLRQNKFKINILSGDRKQTVLALAKKIGFKETEVKWNLLPH
MKLKTIENLKIDNKVAMVGDGINDVPALASSDLGIAVGSGTQIAKANADIVLMGDQLNGLPYSLNLAKKTMRKIKQNLIW
AFGYNLLAIPIAAGILFPKYDILLTPSIAALLMATSSITVVINALSLD

Specific function: Involved in copper transport [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=817, Percent_Identity=31.4565483476132, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI115529486, Length=832, Percent_Identity=28.9663461538462, Blast_Score=352, Evalue=1e-96,
Organism=Homo sapiens, GI55743073, Length=579, Percent_Identity=30.9153713298791, Blast_Score=261, Evalue=1e-69,
Organism=Escherichia coli, GI1786691, Length=774, Percent_Identity=31.9121447028424, Blast_Score=357, Evalue=1e-99,
Organism=Escherichia coli, GI1789879, Length=721, Percent_Identity=27.6005547850208, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1786914, Length=477, Percent_Identity=24.5283018867925, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17556548, Length=821, Percent_Identity=29.9634591961023, Blast_Score=311, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6320475, Length=627, Percent_Identity=34.7687400318979, Blast_Score=309, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6319772, Length=651, Percent_Identity=30.1075268817204, Blast_Score=285, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6325221, Length=588, Percent_Identity=23.2993197278912, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321430, Length=588, Percent_Identity=22.4489795918367, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321271, Length=188, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221329854, Length=594, Percent_Identity=29.2929292929293, Blast_Score=211, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 84439; Mature: 84439

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKESIQLSITGMKCGGCVSTVETILNNSDGIENVSVNLLTESAYFEISYKHIEIETVL
CCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEEECEEEEEEEEEEEHHHHH
EKLKENGFPSKIYINDFSKKINKEELSKKKKWNNQWQKLTFALLLLLFSGLGHLAEGKYI
HHHHHCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEE
NFPILGNIFFHASLATIALLFPGRRIIINGFKSFIKNRPDMDSLVALGVTSAYITSLLSL
CCEEEHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IFPASGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTKDNQIK
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHEEECCCCEE
SIRVNALKPDQEIQILAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEKLSSGSLN
EEEEEEECCCCCEEEEECCCCCCCEEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCCC
LNSTLRLKVQKVGGDSSLAQLVSLIESVNANKPPIQRIADKIAGKFTYFVLIFATLSFFF
CCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WWKGAKHIWPDLLSHNHHQLLTNSSHTLHSSLGSNAENFLSLAIQLSIAVLVIACPCALG
HHCCCHHHCHHHHCCCCCEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
LATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKLFIVDYKNNNDH
CCCCEEEEEECCCCCCCCCEEECCCCEEHHHHCCEEEECCCCCEECCEEEEEEEECCCCC
TYLLRIAASLEKESRHPIANALIQEAQKQNLSLFPIKKILTHSGRGISGELESVEGLINI
EEEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCHHHHCCEEEC
GNIEWLLSKGIVIDNNAKKVIENEETQTHTIIGVSIKDKLLGFILLGDLLREDSIKTVQN
CCEEEEECCCEEEECCCHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHH
LRQNKFKINILSGDRKQTVLALAKKIGFKETEVKWNLLPHMKLKTIENLKIDNKVAMVGD
HHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCEECCEEEEECC
GINDVPALASSDLGIAVGSGTQIAKANADIVLMGDQLNGLPYSLNLAKKTMRKIKQNLIW
CCCCCCCCCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHEH
AFGYNLLAIPIAAGILFPKYDILLTPSIAALLMATSSITVVINALSLD
HHCCHHHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCEEEEEEEEECC
>Mature Secondary Structure
MIRKESIQLSITGMKCGGCVSTVETILNNSDGIENVSVNLLTESAYFEISYKHIEIETVL
CCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEEECEEEEEEEEEEEHHHHH
EKLKENGFPSKIYINDFSKKINKEELSKKKKWNNQWQKLTFALLLLLFSGLGHLAEGKYI
HHHHHCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEE
NFPILGNIFFHASLATIALLFPGRRIIINGFKSFIKNRPDMDSLVALGVTSAYITSLLSL
CCEEEHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IFPASGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTKDNQIK
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHEEECCCCEE
SIRVNALKPDQEIQILAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEKLSSGSLN
EEEEEEECCCCCEEEEECCCCCCCEEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCCC
LNSTLRLKVQKVGGDSSLAQLVSLIESVNANKPPIQRIADKIAGKFTYFVLIFATLSFFF
CCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WWKGAKHIWPDLLSHNHHQLLTNSSHTLHSSLGSNAENFLSLAIQLSIAVLVIACPCALG
HHCCCHHHCHHHHCCCCCEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
LATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKLFIVDYKNNNDH
CCCCEEEEEECCCCCCCCCEEECCCCEEHHHHCCEEEECCCCCEECCEEEEEEEECCCCC
TYLLRIAASLEKESRHPIANALIQEAQKQNLSLFPIKKILTHSGRGISGELESVEGLINI
EEEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCHHHHCCEEEC
GNIEWLLSKGIVIDNNAKKVIENEETQTHTIIGVSIKDKLLGFILLGDLLREDSIKTVQN
CCEEEEECCCEEEECCCHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHH
LRQNKFKINILSGDRKQTVLALAKKIGFKETEVKWNLLPHMKLKTIENLKIDNKVAMVGD
HHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCEECCEEEEECC
GINDVPALASSDLGIAVGSGTQIAKANADIVLMGDQLNGLPYSLNLAKKTMRKIKQNLIW
CCCCCCCCCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHEH
AFGYNLLAIPIAAGILFPKYDILLTPSIAALLMATSSITVVINALSLD
HHCCHHHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7937823 [H]