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The map label for this gene is pdxA

Identifier: 78778413

GI number: 78778413

Start: 28364

End: 29395

Strand: Reverse

Name: pdxA

Synonym: PMT9312_0028

Alternate gene names: 78778413

Gene position: 29395-28364 (Counterclockwise)

Preceding gene: 78778414

Following gene: 78778410

Centisome position: 1.72

GC content: 32.66

Gene sequence:

>1032_bases
ATGAATTTTCAGAATACAAGTAATAGATTGAAATTAGTTTTAAGCGTCGGAGACGAGTCCGGTATTGGACCTGAAATAAT
CTTAAAAGCTCTTTATTCTAATGAGATTCCAGAAAATATTGACTTTGTAATTGTTGGTTCAAAAAAAAATCTACAAAATA
CATATAGAAAACTGAAATCTTTAGGATTAGAAAACCTCGCAAATCCTAAAAATTTAAATATCCATGATCTTGAAATTTCT
TCATCTGATGATTCTAAAGCAAGTTATGGTGATTCAAGTTTTAATTACCTAACAAAAGCAATTGAAATTGTAAAACAATA
TCCTAATTCAGCACTTGTAACTGGACCAATTTGCAAAAAATCATGGTCACTAGCAGGTCATTACTTCTCTGGCCAAACTG
AAGTTTTAGCAAAATCATGCGGAGTAAAAAATGTTGGAATGTTATTCACAGCAAAATCACCAATTACAGGCTGGAGATTA
AATACTTTGCTAGCTACAACCCACATAGCTCTTTGTGAGGTTCCCAAGAAATTAACTACAGAATTAATACATTCTAAATT
AGATCTTTTCAAAGATTTTTGTAGTACCTATGTTGATAAACCTTCTTTTAAAGTTTCAGGATTAAACCCTCATGCTGGTG
AAGAAGGGCTTTTAGGTAATGAAGAAAAAGATTGGCTCAATGATGCGTTGATTGCTTGGAATGAGAATAATAGAGATATT
AAATTATTAGGCCCTTTATCACCAGATAGTTGCTGGAACTCTTCCGCAAAAGCTTGGAGAAACAAAGATGCCGAAAAACA
TGATGGCATTCTTGCTATGTATCATGATCAAGGTTTAATTCCAATGAAAGTTATAGCTCTTAATTATTCAGTAAATATGA
CAATAGGTTTACCCTTTATAAGAACATCTCCAGACCATGGAACAGGATTTGATATTGCTGGCAAAGGAATAGCTGAATCT
CAAAGCATGATTGAAGCTATAATTACAGCCATAGAAATGACTAAAAGTTCAAGACTGCTTAACACGCATTAA

Upstream 100 bases:

>100_bases
TATGCGAAACACTTGGATATAAACTAATTTATAAAAACTATAAAATAGGCTTAAAAAATTGCTTATTAAATAGTTAAAAA
AAATAAATTTTAAACTGTCT

Downstream 100 bases:

>100_bases
AACTTGACCAAATTCAACTGGCGTTCCATTTTCAACGAGAATCTCTACTATTTCTGCATTAAATTCAGATTCTATTTCAT
TCATTAACTTCATAGCTTCC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNFQNTSNRLKLVLSVGDESGIGPEIILKALYSNEIPENIDFVIVGSKKNLQNTYRKLKSLGLENLANPKNLNIHDLEIS
SSDDSKASYGDSSFNYLTKAIEIVKQYPNSALVTGPICKKSWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWRL
NTLLATTHIALCEVPKKLTTELIHSKLDLFKDFCSTYVDKPSFKVSGLNPHAGEEGLLGNEEKDWLNDALIAWNENNRDI
KLLGPLSPDSCWNSSAKAWRNKDAEKHDGILAMYHDQGLIPMKVIALNYSVNMTIGLPFIRTSPDHGTGFDIAGKGIAES
QSMIEAIITAIEMTKSSRLLNTH

Sequences:

>Translated_343_residues
MNFQNTSNRLKLVLSVGDESGIGPEIILKALYSNEIPENIDFVIVGSKKNLQNTYRKLKSLGLENLANPKNLNIHDLEIS
SSDDSKASYGDSSFNYLTKAIEIVKQYPNSALVTGPICKKSWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWRL
NTLLATTHIALCEVPKKLTTELIHSKLDLFKDFCSTYVDKPSFKVSGLNPHAGEEGLLGNEEKDWLNDALIAWNENNRDI
KLLGPLSPDSCWNSSAKAWRNKDAEKHDGILAMYHDQGLIPMKVIALNYSVNMTIGLPFIRTSPDHGTGFDIAGKGIAES
QSMIEAIITAIEMTKSSRLLNTH
>Mature_343_residues
MNFQNTSNRLKLVLSVGDESGIGPEIILKALYSNEIPENIDFVIVGSKKNLQNTYRKLKSLGLENLANPKNLNIHDLEIS
SSDDSKASYGDSSFNYLTKAIEIVKQYPNSALVTGPICKKSWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWRL
NTLLATTHIALCEVPKKLTTELIHSKLDLFKDFCSTYVDKPSFKVSGLNPHAGEEGLLGNEEKDWLNDALIAWNENNRDI
KLLGPLSPDSCWNSSAKAWRNKDAEKHDGILAMYHDQGLIPMKVIALNYSVNMTIGLPFIRTSPDHGTGFDIAGKGIAES
QSMIEAIITAIEMTKSSRLLNTH

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=346, Percent_Identity=32.0809248554913, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 37759; Mature: 37759

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQNTSNRLKLVLSVGDESGIGPEIILKALYSNEIPENIDFVIVGSKKNLQNTYRKLKS
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHH
LGLENLANPKNLNIHDLEISSSDDSKASYGDSSFNYLTKAIEIVKQYPNSALVTGPICKK
CCHHHCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHC
SWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWRLNTLLATTHIALCEVPKKLTT
CCCCCCEEECCCHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHH
ELIHSKLDLFKDFCSTYVDKPSFKVSGLNPHAGEEGLLGNEEKDWLNDALIAWNENNRDI
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHCCEEEEECCCCCEE
KLLGPLSPDSCWNSSAKAWRNKDAEKHDGILAMYHDQGLIPMKVIALNYSVNMTIGLPFI
EEECCCCCCHHCCCCHHHHHCCCCHHHCCEEEEEECCCCCEEEEEEEEEEEEEEEECCEE
RTSPDHGTGFDIAGKGIAESQSMIEAIITAIEMTKSSRLLNTH
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNFQNTSNRLKLVLSVGDESGIGPEIILKALYSNEIPENIDFVIVGSKKNLQNTYRKLKS
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHH
LGLENLANPKNLNIHDLEISSSDDSKASYGDSSFNYLTKAIEIVKQYPNSALVTGPICKK
CCHHHCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHC
SWSLAGHYFSGQTEVLAKSCGVKNVGMLFTAKSPITGWRLNTLLATTHIALCEVPKKLTT
CCCCCCEEECCCHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHH
ELIHSKLDLFKDFCSTYVDKPSFKVSGLNPHAGEEGLLGNEEKDWLNDALIAWNENNRDI
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHCCEEEEECCCCCEE
KLLGPLSPDSCWNSSAKAWRNKDAEKHDGILAMYHDQGLIPMKVIALNYSVNMTIGLPFI
EEECCCCCCHHCCCCHHHHHCCCCHHHCCEEEEEECCCCCEEEEEEEEEEEEEEEECCEE
RTSPDHGTGFDIAGKGIAESQSMIEAIITAIEMTKSSRLLNTH
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA