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The map label for this gene is nagD [H]

Identifier: 78358771

GI number: 78358771

Start: 3689724

End: 3690491

Strand: Direct

Name: nagD [H]

Synonym: Dde_3732

Alternate gene names: 78358771

Gene position: 3689724-3690491 (Clockwise)

Preceding gene: 78358761

Following gene: 78358772

Centisome position: 98.91

GC content: 59.11

Gene sequence:

>768_bases
ATGAATGCCAAACGCTGCTTTGTCTTCGACCTTGACGGCACAGTCTATCTGGGAGACAAGCCCATCCGCCCCACCGTGGA
TTTTATCCGCAACCACTGGGATACTCTCGATTTTCACTTTCTCAGCAACAACACATCCAAGTCTCCGGAAACATACATCC
GCAAACTGCGCGGCATGGGCATAGCCGCCCGCATGGAACAGATTCTTTCACCGGTCACGCCGCTGGTTGCCCATCTGCGG
CATCACGGCATCCGCACGGTCTATCCGGTGGGCAACAACGACTTTGTACGCTGCCTTACCGGTGCCATGCCCGAACTGAC
CATAGGCGAAGAGCATTGTCAGGCGGTCATTCTGGCCTACGACACCGAGTTGACGTATCAAAAACTGGCGCGCTCGGCTT
TGCTGCTGCAGAACCCCGGCGTGGCGTTCCTTGCCACGCATCCGGATCTGGTATGCCCCACTCCCGAAGGCCCCGTGCCC
GACGTGGGCAGCTTTATGGCCCTGTATCACACGGCCACGGGCCGGCGCCCGCAGCACATCTTCGGCAAGCCGGAAACAGC
CGTGCTTGCCCCGCTGCTTGAACGGTACGCGAAAGAAGACATGGTCATGGTGGGTGACAGGCTGTCCACGGACAAGCTGC
TTGCGGAAAATGCAGGAATTGATTTTCTGCTGGTGCTCAGCGGCGAAGCCAGACGGGAAGACCTTGCGGGGCTGGCCCGC
CAGCCTTCTCTTGTGCTGGAGCATCTGGGCGAACTGCAAGGCTACTGA

Upstream 100 bases:

>100_bases
GCCCGTGCTGGACAGACATACAGGCGCGGCGTATCATGCTCGGATACGCATTTTCCGGCAGAGTATTTTCATTTTCGCTC
ATCAACCGCAGGACCAGCGC

Downstream 100 bases:

>100_bases
TTTCTCTCTCAAAATAAGCGTCCGGAAACTGCATGAAAAGTTTCCGGACGCTTTTCCGTTACAATGCCCCCTCACATGCC
CGGCGCAGAATCCATCCGGC

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNAKRCFVFDLDGTVYLGDKPIRPTVDFIRNHWDTLDFHFLSNNTSKSPETYIRKLRGMGIAARMEQILSPVTPLVAHLR
HHGIRTVYPVGNNDFVRCLTGAMPELTIGEEHCQAVILAYDTELTYQKLARSALLLQNPGVAFLATHPDLVCPTPEGPVP
DVGSFMALYHTATGRRPQHIFGKPETAVLAPLLERYAKEDMVMVGDRLSTDKLLAENAGIDFLLVLSGEARREDLAGLAR
QPSLVLEHLGELQGY

Sequences:

>Translated_255_residues
MNAKRCFVFDLDGTVYLGDKPIRPTVDFIRNHWDTLDFHFLSNNTSKSPETYIRKLRGMGIAARMEQILSPVTPLVAHLR
HHGIRTVYPVGNNDFVRCLTGAMPELTIGEEHCQAVILAYDTELTYQKLARSALLLQNPGVAFLATHPDLVCPTPEGPVP
DVGSFMALYHTATGRRPQHIFGKPETAVLAPLLERYAKEDMVMVGDRLSTDKLLAENAGIDFLLVLSGEARREDLAGLAR
QPSLVLEHLGELQGY
>Mature_255_residues
MNAKRCFVFDLDGTVYLGDKPIRPTVDFIRNHWDTLDFHFLSNNTSKSPETYIRKLRGMGIAARMEQILSPVTPLVAHLR
HHGIRTVYPVGNNDFVRCLTGAMPELTIGEEHCQAVILAYDTELTYQKLARSALLLQNPGVAFLATHPDLVCPTPEGPVP
DVGSFMALYHTATGRRPQHIFGKPETAVLAPLLERYAKEDMVMVGDRLSTDKLLAENAGIDFLLVLSGEARREDLAGLAR
QPSLVLEHLGELQGY

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=259, Percent_Identity=27.7992277992278, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1786890, Length=252, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71984613, Length=274, Percent_Identity=28.4671532846715, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562458, Length=266, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558880, Length=272, Percent_Identity=28.6764705882353, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560956, Length=266, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193210059, Length=260, Percent_Identity=28.4615384615385, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI86563050, Length=252, Percent_Identity=28.968253968254, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666141, Length=252, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641437, Length=243, Percent_Identity=28.3950617283951, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24666137, Length=287, Percent_Identity=27.5261324041812, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859765, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 28331; Mature: 28331

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKRCFVFDLDGTVYLGDKPIRPTVDFIRNHWDTLDFHFLSNNTSKSPETYIRKLRGMG
CCCCEEEEEECCCEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCC
IAARMEQILSPVTPLVAHLRHHGIRTVYPVGNNDFVRCLTGAMPELTIGEEHCQAVILAY
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCCCCHHHHCEEEEEE
DTELTYQKLARSALLLQNPGVAFLATHPDLVCPTPEGPVPDVGSFMALYHTATGRRPQHI
CCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCHHH
FGKPETAVLAPLLERYAKEDMVMVGDRLSTDKLLAENAGIDFLLVLSGEARREDLAGLAR
CCCCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHC
QPSLVLEHLGELQGY
CHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAKRCFVFDLDGTVYLGDKPIRPTVDFIRNHWDTLDFHFLSNNTSKSPETYIRKLRGMG
CCCCEEEEEECCCEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCC
IAARMEQILSPVTPLVAHLRHHGIRTVYPVGNNDFVRCLTGAMPELTIGEEHCQAVILAY
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCCCCHHHHCEEEEEE
DTELTYQKLARSALLLQNPGVAFLATHPDLVCPTPEGPVPDVGSFMALYHTATGRRPQHI
CCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCHHH
FGKPETAVLAPLLERYAKEDMVMVGDRLSTDKLLAENAGIDFLLVLSGEARREDLAGLAR
CCCCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHC
QPSLVLEHLGELQGY
CHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA