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The map label for this gene is glpD

Identifier: 78358772

GI number: 78358772

Start: 3690682

End: 3692184

Strand: Direct

Name: glpD

Synonym: Dde_3733

Alternate gene names: 78358772

Gene position: 3690682-3692184 (Clockwise)

Preceding gene: 78358771

Following gene: 78358777

Centisome position: 98.94

GC content: 59.02

Gene sequence:

>1503_bases
ATGGAAACGAACATTTATGATGTGCTTATTGTCGGTGGCGGCATCAACGGTGCCTCCGCGGCCCGCGATGCGGCCGGCCG
AGGGCTTTCCGTTGCACTCTGCGAGGCCGAAGACATAGGCTGGGCAACGTCCTCCGCGTCGTCCAAGCTTATTCACGGCG
GCCTGCGCTATCTTGAACACTATGAATTCAGACTGGTGCGCGAAGCCCTGGCGGAACGCGAGGTAATCCTCGCCAATGCG
CCGCACATTTCATGGCCCATGCGCATCGTGCTCCCCCATGCTCCGTGGCTGCGACCGGCGTGGCTCATCCGCGCCGGACT
GTTCCTCTATGACCACCTGAGCCCGCTGCGGCAGATTGCCGGATCAGAAAAAGTCAATCTGAAAAAGCATCTCGCCGGAA
GGCCGCTTTCGGACAAATTCAAAACCGGCTTTGAATATTCCGACCTCGGCGTGCTGGACACCCGTTTCTGCCTGTACAAT
GCCCTTGACGCGGCACTGCGCGGTGCGGCGGTGCACACGCGAACCCGCGTGGAAAAAGCCGTGCGCGAAAACGGCCTGTG
GGTGGCCCGCATCCGCAACACCCGTACCGGCGAAGAAAGCGAAATCAGAGCGCGCTCCATGGTCAACACAACCGGCCCAT
GGAGCAACGAATTTCTGACCAGCAGGGCTGAATCCAGCGATTCCGGCCGTATCCGCATGGTACTGGGCAGCCATATCATC
GTGCCCAGACTGTACGATCATCCGTACAGCTATATTCTGCAGAACGACGACAACCGCATCGTGTTCGCCATTCCGTATGA
ATATGATTACACGATGATAGGCACCACTGATGTGGACTATCAGGGAGACCCCGCAAACGCTGCCTGTTCTCAGGCCGAAC
GCGAATACCTGTGCAAAATCACCAACAGCTACTTCCGCACGCAGATTACGCCCGAAGATATCGTCTGGGACTTTGCAGGT
ATCCGGCCGCTGTACTCTGACGGTAAGGATGCCACATCCGCCACACGCGATTATGTTTTCAAGGTGGAAAAAGACGCCGC
CGGCAATGCCCCGCTGCTGAATGTTTTCGGCGGCAAGATAACGGCAGGCCGCGAGATAGGCGAAAAAATCGTCAACCAGC
TGCTGCCGCTGCTGGGCCGCAGCGAGGCGCCCGAAACCAGCCAGTGGACAGCCACAGCTCCTCTGCCCGGCGGCGACATG
CCCGAAGGCTTCGATGCCTATCTGTACGCTTTTCACCGCCGGTACCCGTGGCTGCCGGAACGCATGGCACACAGGCTGTG
CCGCCACTACGGCACGCTGGCACACGATGTGCTGGCCGGTGCAACCAGCCTTGACGATCTGGGTGAACACTTCGGCGGCG
GGCTGTATGAAGCCGAAGTACGCTATCAGCAGAAAAATGAATGGGCCGATGATGCCGAAAGCGTCATCTGGCGCCGTACG
CGCCTTGGCCTGCATATGACTGAAGAAGAACAGGACAGGCTGCGTCGCTGGTTCGACGCATAA

Upstream 100 bases:

>100_bases
TCCATCCGGCTTTTTTTCGCACCTGTTTCGTTTTTCCTTTTTTATTTTCGTTTGCGAAAATTATTTTGACCATTCCGAAA
GCAGGGTCTATGCTGCCCCC

Downstream 100 bases:

>100_bases
CCTCCTTCACACGTGTTCTCCTCACTCCACTGCGGCGGTCTGCGAAAGCGGGCCGCCGTACTTTGTTGCATGCAGCAGAA
AAGCCCGCACCTGTTCTGGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
METNIYDVLIVGGGINGASAARDAAGRGLSVALCEAEDIGWATSSASSKLIHGGLRYLEHYEFRLVREALAEREVILANA
PHISWPMRIVLPHAPWLRPAWLIRAGLFLYDHLSPLRQIAGSEKVNLKKHLAGRPLSDKFKTGFEYSDLGVLDTRFCLYN
ALDAALRGAAVHTRTRVEKAVRENGLWVARIRNTRTGEESEIRARSMVNTTGPWSNEFLTSRAESSDSGRIRMVLGSHII
VPRLYDHPYSYILQNDDNRIVFAIPYEYDYTMIGTTDVDYQGDPANAACSQAEREYLCKITNSYFRTQITPEDIVWDFAG
IRPLYSDGKDATSATRDYVFKVEKDAAGNAPLLNVFGGKITAGREIGEKIVNQLLPLLGRSEAPETSQWTATAPLPGGDM
PEGFDAYLYAFHRRYPWLPERMAHRLCRHYGTLAHDVLAGATSLDDLGEHFGGGLYEAEVRYQQKNEWADDAESVIWRRT
RLGLHMTEEEQDRLRRWFDA

Sequences:

>Translated_500_residues
METNIYDVLIVGGGINGASAARDAAGRGLSVALCEAEDIGWATSSASSKLIHGGLRYLEHYEFRLVREALAEREVILANA
PHISWPMRIVLPHAPWLRPAWLIRAGLFLYDHLSPLRQIAGSEKVNLKKHLAGRPLSDKFKTGFEYSDLGVLDTRFCLYN
ALDAALRGAAVHTRTRVEKAVRENGLWVARIRNTRTGEESEIRARSMVNTTGPWSNEFLTSRAESSDSGRIRMVLGSHII
VPRLYDHPYSYILQNDDNRIVFAIPYEYDYTMIGTTDVDYQGDPANAACSQAEREYLCKITNSYFRTQITPEDIVWDFAG
IRPLYSDGKDATSATRDYVFKVEKDAAGNAPLLNVFGGKITAGREIGEKIVNQLLPLLGRSEAPETSQWTATAPLPGGDM
PEGFDAYLYAFHRRYPWLPERMAHRLCRHYGTLAHDVLAGATSLDDLGEHFGGGLYEAEVRYQQKNEWADDAESVIWRRT
RLGLHMTEEEQDRLRRWFDA
>Mature_500_residues
METNIYDVLIVGGGINGASAARDAAGRGLSVALCEAEDIGWATSSASSKLIHGGLRYLEHYEFRLVREALAEREVILANA
PHISWPMRIVLPHAPWLRPAWLIRAGLFLYDHLSPLRQIAGSEKVNLKKHLAGRPLSDKFKTGFEYSDLGVLDTRFCLYN
ALDAALRGAAVHTRTRVEKAVRENGLWVARIRNTRTGEESEIRARSMVNTTGPWSNEFLTSRAESSDSGRIRMVLGSHII
VPRLYDHPYSYILQNDDNRIVFAIPYEYDYTMIGTTDVDYQGDPANAACSQAEREYLCKITNSYFRTQITPEDIVWDFAG
IRPLYSDGKDATSATRDYVFKVEKDAAGNAPLLNVFGGKITAGREIGEKIVNQLLPLLGRSEAPETSQWTATAPLPGGDM
PEGFDAYLYAFHRRYPWLPERMAHRLCRHYGTLAHDVLAGATSLDDLGEHFGGGLYEAEVRYQQKNEWADDAESVIWRRT
RLGLHMTEEEQDRLRRWFDA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=526, Percent_Identity=29.6577946768061, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI285002231, Length=526, Percent_Identity=29.6577946768061, Blast_Score=169, Evalue=7e-42,
Organism=Escherichia coli, GI2367226, Length=471, Percent_Identity=45.859872611465, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1788574, Length=394, Percent_Identity=26.9035532994924, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534726, Length=509, Percent_Identity=30.4518664047151, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17509253, Length=516, Percent_Identity=30.8139534883721, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322036, Length=479, Percent_Identity=30.062630480167, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI161077125, Length=522, Percent_Identity=28.735632183908, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24653942, Length=522, Percent_Identity=28.735632183908, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24653944, Length=522, Percent_Identity=28.735632183908, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI20130025, Length=522, Percent_Identity=28.735632183908, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24586295, Length=519, Percent_Identity=28.3236994219653, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19921278, Length=507, Percent_Identity=26.0355029585799, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56301; Mature: 56301

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNIYDVLIVGGGINGASAARDAAGRGLSVALCEAEDIGWATSSASSKLIHGGLRYLEH
CCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
YEFRLVREALAEREVILANAPHISWPMRIVLPHAPWLRPAWLIRAGLFLYDHLSPLRQIA
HHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GSEKVNLKKHLAGRPLSDKFKTGFEYSDLGVLDTRFCLYNALDAALRGAAVHTRTRVEKA
CCCCCCHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VRENGLWVARIRNTRTGEESEIRARSMVNTTGPWSNEFLTSRAESSDSGRIRMVLGSHII
HHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCEEE
VPRLYDHPYSYILQNDDNRIVFAIPYEYDYTMIGTTDVDYQGDPANAACSQAEREYLCKI
ECCCCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
TNSYFRTQITPEDIVWDFAGIRPLYSDGKDATSATRDYVFKVEKDAAGNAPLLNVFGGKI
HHHHHEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCEEEECCCCE
TAGREIGEKIVNQLLPLLGRSEAPETSQWTATAPLPGGDMPEGFDAYLYAFHRRYPWLPE
ECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHH
RMAHRLCRHYGTLAHDVLAGATSLDDLGEHFGGGLYEAEVRYQQKNEWADDAESVIWRRT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEHHHHHHHCCCCHHHHHHHHHHH
RLGLHMTEEEQDRLRRWFDA
HCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
METNIYDVLIVGGGINGASAARDAAGRGLSVALCEAEDIGWATSSASSKLIHGGLRYLEH
CCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
YEFRLVREALAEREVILANAPHISWPMRIVLPHAPWLRPAWLIRAGLFLYDHLSPLRQIA
HHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GSEKVNLKKHLAGRPLSDKFKTGFEYSDLGVLDTRFCLYNALDAALRGAAVHTRTRVEKA
CCCCCCHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VRENGLWVARIRNTRTGEESEIRARSMVNTTGPWSNEFLTSRAESSDSGRIRMVLGSHII
HHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCEEE
VPRLYDHPYSYILQNDDNRIVFAIPYEYDYTMIGTTDVDYQGDPANAACSQAEREYLCKI
ECCCCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
TNSYFRTQITPEDIVWDFAGIRPLYSDGKDATSATRDYVFKVEKDAAGNAPLLNVFGGKI
HHHHHEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCEEEECCCCE
TAGREIGEKIVNQLLPLLGRSEAPETSQWTATAPLPGGDMPEGFDAYLYAFHRRYPWLPE
ECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHH
RMAHRLCRHYGTLAHDVLAGATSLDDLGEHFGGGLYEAEVRYQQKNEWADDAESVIWRRT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEHHHHHHHCCCCHHHHHHHHHHH
RLGLHMTEEEQDRLRRWFDA
HCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]