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The map label for this gene is ribF [H]

Identifier: 78358544

GI number: 78358544

Start: 3464444

End: 3465388

Strand: Reverse

Name: ribF [H]

Synonym: Dde_3505

Alternate gene names: 78358544

Gene position: 3465388-3464444 (Counterclockwise)

Preceding gene: 78358545

Following gene: 78358543

Centisome position: 92.9

GC content: 55.34

Gene sequence:

>945_bases
ATGCAGATCGCAAGACAGCTTCAGGAAATAACCCTTGATCTTTCCGGCGGGTCGTGTGTCACCATCGGCAATTTTGACGG
TGTGCACAACGGCCACCGCAAGCTTATAGGCCGCATGATGGCCAAAGCCGCCAAGGCTTCGTTGCCGGGTGTGGTGGTCA
CGTTCTGTCCGCATCCGCTAAGGGTGCTTGTGGGCCCGCATACCCCCCCGTTCATTACTGATTATGAAAAAAAACTTGAC
CTGCTGGAAGCGCTGGGGGTTGATCTGACCCTTATGCTGCAGTTCACGCGGGAACTGGCGGCGCTGGAGCCTGAAGAATT
TGTGCGCAGTATTCTGGTGGACGGCCTGAATGTGAAGGAGCTGGTCGTAGGGTACGATTACTCCTTTGGCAAAGGGCGCA
AGGGACACTTTGAGCTGCTGGTGGAACTGGGAGAAAAATACGGCTTTTCATGTGAGCGGCTGGACCCTGTCATCATCGAC
GGTGCCGTGGTAAGTTCCACGCGCATACGTGATATGATTAAGGCCGGTGATGTATGGGGAGTGCGGCCTCTCATGGACAG
GTTCTATGTGGTGCGGGGCACTGTTGTGCACGGTAAAAAACGCGGAGGCCGGCTGCTGGGTTTTCCCACGGCCAACCTTG
AGGTGAGGGACGAGCTTGTTCCGGGACCGGGCGTATACGCCGTGTGGGTTGAAGTGGACGGCAACCTGTACAAGGGTGTC
ACCAATATCGGGTACAATCCCACATTCGGCAACGAGACGCTGAGTGTGGAAACATATATTATGGATTTTGACCGCGACAT
CTACGGATGGGAGCTGCGGTTGAATTTTGTGCACAGGCTGCGGGATGAACGCAAGTTTTCGGGTCTTGACGATCTGATGA
CGCAGATTCGCAGCGATGTGGAACTGGGGCGGCAGATACTGGATTCTCAGGAAGCCGGACTGTAG

Upstream 100 bases:

>100_bases
TATGCTTGAACGGATGCGGGTTTTGGGGTAGCTATAGCGGTCTTCGGCGGGCCGAACGGATATTTCCGGCGCCCAACCCA
ACCCGGAGAACGGGAACCCC

Downstream 100 bases:

>100_bases
CCTCCCTCTGCGTTGTTTCGCGCCTTTCTGTACGCCGCCCGGCACCGCCGCGCGGCGTGGCGGTGTTTGCACCGTGCAAA
AGCGGGGCGGCAGTTATCTG

Product: riboflavin kinase / FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MQIARQLQEITLDLSGGSCVTIGNFDGVHNGHRKLIGRMMAKAAKASLPGVVVTFCPHPLRVLVGPHTPPFITDYEKKLD
LLEALGVDLTLMLQFTRELAALEPEEFVRSILVDGLNVKELVVGYDYSFGKGRKGHFELLVELGEKYGFSCERLDPVIID
GAVVSSTRIRDMIKAGDVWGVRPLMDRFYVVRGTVVHGKKRGGRLLGFPTANLEVRDELVPGPGVYAVWVEVDGNLYKGV
TNIGYNPTFGNETLSVETYIMDFDRDIYGWELRLNFVHRLRDERKFSGLDDLMTQIRSDVELGRQILDSQEAGL

Sequences:

>Translated_314_residues
MQIARQLQEITLDLSGGSCVTIGNFDGVHNGHRKLIGRMMAKAAKASLPGVVVTFCPHPLRVLVGPHTPPFITDYEKKLD
LLEALGVDLTLMLQFTRELAALEPEEFVRSILVDGLNVKELVVGYDYSFGKGRKGHFELLVELGEKYGFSCERLDPVIID
GAVVSSTRIRDMIKAGDVWGVRPLMDRFYVVRGTVVHGKKRGGRLLGFPTANLEVRDELVPGPGVYAVWVEVDGNLYKGV
TNIGYNPTFGNETLSVETYIMDFDRDIYGWELRLNFVHRLRDERKFSGLDDLMTQIRSDVELGRQILDSQEAGL
>Mature_314_residues
MQIARQLQEITLDLSGGSCVTIGNFDGVHNGHRKLIGRMMAKAAKASLPGVVVTFCPHPLRVLVGPHTPPFITDYEKKLD
LLEALGVDLTLMLQFTRELAALEPEEFVRSILVDGLNVKELVVGYDYSFGKGRKGHFELLVELGEKYGFSCERLDPVIID
GAVVSSTRIRDMIKAGDVWGVRPLMDRFYVVRGTVVHGKKRGGRLLGFPTANLEVRDELVPGPGVYAVWVEVDGNLYKGV
TNIGYNPTFGNETLSVETYIMDFDRDIYGWELRLNFVHRLRDERKFSGLDDLMTQIRSDVELGRQILDSQEAGL

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Homo sapiens, GI269973877, Length=129, Percent_Identity=39.5348837209302, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1786208, Length=308, Percent_Identity=35.7142857142857, Blast_Score=189, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17541882, Length=122, Percent_Identity=36.8852459016393, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644927, Length=125, Percent_Identity=41.6, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 35099; Mature: 35099

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIARQLQEITLDLSGGSCVTIGNFDGVHNGHRKLIGRMMAKAAKASLPGVVVTFCPHPL
CCHHHHHHHHEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCE
RVLVGPHTPPFITDYEKKLDLLEALGVDLTLMLQFTRELAALEPEEFVRSILVDGLNVKE
EEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHH
LVVGYDYSFGKGRKGHFELLVELGEKYGFSCERLDPVIIDGAVVSSTRIRDMIKAGDVWG
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCEEECCEEHHHHHHHHHHHCCCCCC
VRPLMDRFYVVRGTVVHGKKRGGRLLGFPTANLEVRDELVPGPGVYAVWVEVDGNLYKGV
HHHHHHHEEHEEEEEEECCCCCCEEEECCCCCCEEHHCCCCCCCEEEEEEEECCCEEECH
TNIGYNPTFGNETLSVETYIMDFDRDIYGWELRLNFVHRLRDERKFSGLDDLMTQIRSDV
HHCCCCCCCCCCEEEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELGRQILDSQEAGL
HHHHHHHHHHCCCC
>Mature Secondary Structure
MQIARQLQEITLDLSGGSCVTIGNFDGVHNGHRKLIGRMMAKAAKASLPGVVVTFCPHPL
CCHHHHHHHHEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCE
RVLVGPHTPPFITDYEKKLDLLEALGVDLTLMLQFTRELAALEPEEFVRSILVDGLNVKE
EEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHH
LVVGYDYSFGKGRKGHFELLVELGEKYGFSCERLDPVIIDGAVVSSTRIRDMIKAGDVWG
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCEEECCEEHHHHHHHHHHHCCCCCC
VRPLMDRFYVVRGTVVHGKKRGGRLLGFPTANLEVRDELVPGPGVYAVWVEVDGNLYKGV
HHHHHHHEEHEEEEEEECCCCCCEEEECCCCCCEEHHCCCCCCCEEEEEEEECCCEEECH
TNIGYNPTFGNETLSVETYIMDFDRDIYGWELRLNFVHRLRDERKFSGLDDLMTQIRSDV
HHCCCCCCCCCCEEEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELGRQILDSQEAGL
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7772835; 3023344 [H]