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The map label for this gene is tyrA [H]

Identifier: 78358524

GI number: 78358524

Start: 3445565

End: 3446347

Strand: Reverse

Name: tyrA [H]

Synonym: Dde_3485

Alternate gene names: 78358524

Gene position: 3446347-3445565 (Counterclockwise)

Preceding gene: 78358525

Following gene: 78358523

Centisome position: 92.39

GC content: 62.2

Gene sequence:

>783_bases
ATGCGTATAGACAATGTTGCCGTGGTGGGCGCGGACGGCCGCATGGGGCAGCTGTTCTGCGCGCGGGCCCGTGCGGCCGG
CATGGGGGTGGTCGCTCTGGACAGGCCTCTGGAGCCGGAAGCCGTGCGGCAGGCTGTGCACGGGGTCCAGATGGTGTTGC
TGTGTGTTCCGGCAGCAGTACTTGACAGAGTAGCTGGACTCATGTCAGGTATTCTCTCAGGTAATCAGATTCTGGCAGAC
ATAACTTCGGTAAAGGTTCTTCCCATGCAGCAGATGCGCAGACAGTACAGCGGCCCCGTGGTGGGTACGCATCCTCTTTT
CGGGCCGGCGCCCGCGCAGGGCGAAACCCGCGTGGCCGTTGTTCCCGACAGCGGCCATGCTGCCGGTGAAGCGGCCTGCG
CCGCGGTGGAGGATTTTTTTGTGCGTCTGGGGTGCGAGCCTTTCCGTACCACGGCGCAGGAACACGACCGTGCGGCCGCG
TGCATCCAGAATCTCAACTTCATCACGTCCGTGGCATATTTTGCCACACTGGCGCATGACGACGCCATTACGCCTTTTCT
TACTCCTTCGTTCCGCCGCAGGCTGGACGCCGCACGTAAAATGCTGACCGAAGACGCCGAACTTTTCGAAGGGCTTTTCG
AGGCCAACCCCTACAGTCAGGACGCCGTGCGTGCGTTCCGTGCCATTCTGAATCATGCCTGCGCAGGTGACGTGAATCTG
CTCGTCGACCGTGCCGGCTGGTGGTGGCGCTCCTCGGATAACAGGGGAGGTGCGCCCTCGTAG

Upstream 100 bases:

>100_bases
CTGTGCTGGAAATGGCCGGACAGCCCGTCACCGTGGATGATCCTGCCTGTGTGGGCAAATCATTTCCCGCATTCTGGGAA
CAGTGGAAAAAGGTTTCGCC

Downstream 100 bases:

>100_bases
CGCATGGCAGCACGATATGTGCAACAGTTTGGTTGATACCAAGGCCGCATCCTCCCCGGATGCGGCCTTTTTTGTTTTTA
CCGCCGGAACCACCGCAAAG

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MRIDNVAVVGADGRMGQLFCARARAAGMGVVALDRPLEPEAVRQAVHGVQMVLLCVPAAVLDRVAGLMSGILSGNQILAD
ITSVKVLPMQQMRRQYSGPVVGTHPLFGPAPAQGETRVAVVPDSGHAAGEAACAAVEDFFVRLGCEPFRTTAQEHDRAAA
CIQNLNFITSVAYFATLAHDDAITPFLTPSFRRRLDAARKMLTEDAELFEGLFEANPYSQDAVRAFRAILNHACAGDVNL
LVDRAGWWWRSSDNRGGAPS

Sequences:

>Translated_260_residues
MRIDNVAVVGADGRMGQLFCARARAAGMGVVALDRPLEPEAVRQAVHGVQMVLLCVPAAVLDRVAGLMSGILSGNQILAD
ITSVKVLPMQQMRRQYSGPVVGTHPLFGPAPAQGETRVAVVPDSGHAAGEAACAAVEDFFVRLGCEPFRTTAQEHDRAAA
CIQNLNFITSVAYFATLAHDDAITPFLTPSFRRRLDAARKMLTEDAELFEGLFEANPYSQDAVRAFRAILNHACAGDVNL
LVDRAGWWWRSSDNRGGAPS
>Mature_260_residues
MRIDNVAVVGADGRMGQLFCARARAAGMGVVALDRPLEPEAVRQAVHGVQMVLLCVPAAVLDRVAGLMSGILSGNQILAD
ITSVKVLPMQQMRRQYSGPVVGTHPLFGPAPAQGETRVAVVPDSGHAAGEAACAAVEDFFVRLGCEPFRTTAQEHDRAAA
CIQNLNFITSVAYFATLAHDDAITPFLTPSFRRRLDAARKMLTEDAELFEGLFEANPYSQDAVRAFRAILNHACAGDVNL
LVDRAGWWWRSSDNRGGAPS

Specific function: Tyrosine biosynthesis [C]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

Organism=Escherichia coli, GI1788952, Length=208, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR008244
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR011277
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF01817 CM_2; PF02153 PDH [H]

EC number: =5.4.99.5; =1.3.1.12 [H]

Molecular weight: Translated: 27914; Mature: 27914

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDNVAVVGADGRMGQLFCARARAAGMGVVALDRPLEPEAVRQAVHGVQMVLLCVPAAV
CCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LDRVAGLMSGILSGNQILADITSVKVLPMQQMRRQYSGPVVGTHPLFGPAPAQGETRVAV
HHHHHHHHHHHHCCCHHHHHHHHHEECCHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEE
VPDSGHAAGEAACAAVEDFFVRLGCEPFRTTAQEHDRAAACIQNLNFITSVAYFATLAHD
ECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAITPFLTPSFRRRLDAARKMLTEDAELFEGLFEANPYSQDAVRAFRAILNHACAGDVNL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHE
LVDRAGWWWRSSDNRGGAPS
EEECCCCEEECCCCCCCCCC
>Mature Secondary Structure
MRIDNVAVVGADGRMGQLFCARARAAGMGVVALDRPLEPEAVRQAVHGVQMVLLCVPAAV
CCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LDRVAGLMSGILSGNQILADITSVKVLPMQQMRRQYSGPVVGTHPLFGPAPAQGETRVAV
HHHHHHHHHHHHCCCHHHHHHHHHEECCHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEE
VPDSGHAAGEAACAAVEDFFVRLGCEPFRTTAQEHDRAAACIQNLNFITSVAYFATLAHD
ECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DAITPFLTPSFRRRLDAARKMLTEDAELFEGLFEANPYSQDAVRAFRAILNHACAGDVNL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHE
LVDRAGWWWRSSDNRGGAPS
EEECCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512561 [H]