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The map label for this gene is aroA [H]

Identifier: 78358525

GI number: 78358525

Start: 3446338

End: 3447666

Strand: Reverse

Name: aroA [H]

Synonym: Dde_3486

Alternate gene names: 78358525

Gene position: 3447666-3446338 (Counterclockwise)

Preceding gene: 78358526

Following gene: 78358524

Centisome position: 92.42

GC content: 63.28

Gene sequence:

>1329_bases
ATGAACAGCAAGACCGTAACGGCTCCGGCCTCCAAATCCGTGTCCCACCGCATGGTCATAGGTGCCGCGCTGGCCGCCGG
CACTTCCACGCTGACCAACGTGCTGGAAAGTGATGATCTGACGCGCACCGTGGAGATAATGAAAACCTGCGGCGCAGACA
TTGTGCGGCAGGGTGCAGGCCGGTATTCGGTGCGTGGTGTGGCCGGTACGCCGCGCGGCGGCAGTACCGAACCCGCTTCG
TGCTATGTGCACGAATCCGGCACCACCTGCAGGCTGCTGACCGCGGTTGTGGCGTGCGGGCTGGGCACGTTCCGCATTCA
CGGGGTGCCCCGCATGCATGAACGTCCCATAGGCGAACTGGTCACCGCTTTGCGCATGGCCGGGGCTGATGTGCGCTATG
AACAGCATGAGGGGTTTCCGCCGCTCATTGTCGAGGCGCTGGGACTTTCGGGCGGCATGGTGACCATCGGGCTGGACGAA
TCCAGCCAGTACCTGTCGGGGCTTCTGCTGGCCGCGCCGCAGGCGCGTTCCATGACAATCACCGTGGGCGGAGCCAAAGT
GGTCTCGTGGCCCTATGTGGGGCTGACGTTGCAGGCCATGGAGGATTTCGGACTGCGTTTCAGCGTGGAGACAAAGGACG
ACGAAGGCTGGCACAAGACAGACTGGCGGACAGTGAAGGATATCGTGCCCGGCAGGGTGCGGTTTGTGGTACCCCCCGGC
ATGTACAGAGCCGGTGACTATACCGTGGAAGGCGACTGGTCCAGTTCGTCGTATTTTCTTGCCGCGGGAGCGGCGGGGCA
GGTTCCCGTAACCGTGCGGGGGTTGCGCCGCGATTCTCTGCAGGGTGACCGCGCCATGCTGGATATTCTCCGGCGCATGG
GGGCCGGTGTGGCATGGGACGGCGACGCCGTCACCGTGAGCCCGGCTCCGCTCAAAGGGATAGCGGTGGACATGGGCCAC
TGTCCTGACCTTGTTCCCACCGTGGCCACAGTGGCTGCTTTTGCCTCGGGTGACACCACCATCAGCAATGTGGGGCACCT
GCGCATCAAAGAATGCGACCGTCTTGCCTCGCCTGCCGCGGAACTTGCCCGCGCGGGTGTGCAGTGCGAGGTGCGCGACG
ACGGTCTGGTGGTGCACGGCGCAGGCAGAGAAAATATCCGGATAGCACCCGGCACCGTGTTCAGCACCTACGCGGACCAC
CGTATGGCCATGAGCATGGCTGTGCTGGAAATGGCCGGACAGCCCGTCACCGTGGATGATCCTGCCTGTGTGGGCAAATC
ATTTCCCGCATTCTGGGAACAGTGGAAAAAGGTTTCGCCATGCGTATAG

Upstream 100 bases:

>100_bases
TGTGGCCCGCACGGCCGATGGTTCGGAACGGCTGGTGACCGAATAGTTTTTTTAGCGCACGACGCCCGCAGGGGCGCACA
AGCATACGACGGATGAACGC

Downstream 100 bases:

>100_bases
ACAATGTTGCCGTGGTGGGCGCGGACGGCCGCATGGGGCAGCTGTTCTGCGCGCGGGCCCGTGCGGCCGGCATGGGGGTG
GTCGCTCTGGACAGGCCTCT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNSKTVTAPASKSVSHRMVIGAALAAGTSTLTNVLESDDLTRTVEIMKTCGADIVRQGAGRYSVRGVAGTPRGGSTEPAS
CYVHESGTTCRLLTAVVACGLGTFRIHGVPRMHERPIGELVTALRMAGADVRYEQHEGFPPLIVEALGLSGGMVTIGLDE
SSQYLSGLLLAAPQARSMTITVGGAKVVSWPYVGLTLQAMEDFGLRFSVETKDDEGWHKTDWRTVKDIVPGRVRFVVPPG
MYRAGDYTVEGDWSSSSYFLAAGAAGQVPVTVRGLRRDSLQGDRAMLDILRRMGAGVAWDGDAVTVSPAPLKGIAVDMGH
CPDLVPTVATVAAFASGDTTISNVGHLRIKECDRLASPAAELARAGVQCEVRDDGLVVHGAGRENIRIAPGTVFSTYADH
RMAMSMAVLEMAGQPVTVDDPACVGKSFPAFWEQWKKVSPCV

Sequences:

>Translated_442_residues
MNSKTVTAPASKSVSHRMVIGAALAAGTSTLTNVLESDDLTRTVEIMKTCGADIVRQGAGRYSVRGVAGTPRGGSTEPAS
CYVHESGTTCRLLTAVVACGLGTFRIHGVPRMHERPIGELVTALRMAGADVRYEQHEGFPPLIVEALGLSGGMVTIGLDE
SSQYLSGLLLAAPQARSMTITVGGAKVVSWPYVGLTLQAMEDFGLRFSVETKDDEGWHKTDWRTVKDIVPGRVRFVVPPG
MYRAGDYTVEGDWSSSSYFLAAGAAGQVPVTVRGLRRDSLQGDRAMLDILRRMGAGVAWDGDAVTVSPAPLKGIAVDMGH
CPDLVPTVATVAAFASGDTTISNVGHLRIKECDRLASPAAELARAGVQCEVRDDGLVVHGAGRENIRIAPGTVFSTYADH
RMAMSMAVLEMAGQPVTVDDPACVGKSFPAFWEQWKKVSPCV
>Mature_442_residues
MNSKTVTAPASKSVSHRMVIGAALAAGTSTLTNVLESDDLTRTVEIMKTCGADIVRQGAGRYSVRGVAGTPRGGSTEPAS
CYVHESGTTCRLLTAVVACGLGTFRIHGVPRMHERPIGELVTALRMAGADVRYEQHEGFPPLIVEALGLSGGMVTIGLDE
SSQYLSGLLLAAPQARSMTITVGGAKVVSWPYVGLTLQAMEDFGLRFSVETKDDEGWHKTDWRTVKDIVPGRVRFVVPPG
MYRAGDYTVEGDWSSSSYFLAAGAAGQVPVTVRGLRRDSLQGDRAMLDILRRMGAGVAWDGDAVTVSPAPLKGIAVDMGH
CPDLVPTVATVAAFASGDTTISNVGHLRIKECDRLASPAAELARAGVQCEVRDDGLVVHGAGRENIRIAPGTVFSTYADH
RMAMSMAVLEMAGQPVTVDDPACVGKSFPAFWEQWKKVSPCV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=442, Percent_Identity=37.10407239819, Blast_Score=259, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6320332, Length=467, Percent_Identity=32.1199143468951, Blast_Score=191, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46832; Mature: 46832

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKTVTAPASKSVSHRMVIGAALAAGTSTLTNVLESDDLTRTVEIMKTCGADIVRQGAG
CCCCEECCCCCCCCCHHHEEHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHCCCC
RYSVRGVAGTPRGGSTEPASCYVHESGTTCRLLTAVVACGLGTFRIHGVPRMHERPIGEL
CEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHCCCHHHH
VTALRMAGADVRYEQHEGFPPLIVEALGLSGGMVTIGLDESSQYLSGLLLAAPQARSMTI
HHHHHHCCCCCEEHHCCCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHEECCCCCEEEE
TVGGAKVVSWPYVGLTLQAMEDFGLRFSVETKDDEGWHKTDWRTVKDIVPGRVRFVVPPG
EECCCEEEECCCCCEEEEEHHHCCCEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEECCC
MYRAGDYTVEGDWSSSSYFLAAGAAGQVPVTVRGLRRDSLQGDRAMLDILRRMGAGVAWD
CEECCCEEEECCCCCCCEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEEC
GDAVTVSPAPLKGIAVDMGHCPDLVPTVATVAAFASGDTTISNVGHLRIKECDRLASPAA
CCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEECCCCCEEHHHHHHHCCCHH
ELARAGVQCEVRDDGLVVHGAGRENIRIAPGTVFSTYADHRMAMSMAVLEMAGQPVTVDD
HHHHCCCEEEEECCCEEEECCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHCCCCEECCC
PACVGKSFPAFWEQWKKVSPCV
HHHCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MNSKTVTAPASKSVSHRMVIGAALAAGTSTLTNVLESDDLTRTVEIMKTCGADIVRQGAG
CCCCEECCCCCCCCCHHHEEHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHCCCC
RYSVRGVAGTPRGGSTEPASCYVHESGTTCRLLTAVVACGLGTFRIHGVPRMHERPIGEL
CEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHCCCHHHH
VTALRMAGADVRYEQHEGFPPLIVEALGLSGGMVTIGLDESSQYLSGLLLAAPQARSMTI
HHHHHHCCCCCEEHHCCCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHEECCCCCEEEE
TVGGAKVVSWPYVGLTLQAMEDFGLRFSVETKDDEGWHKTDWRTVKDIVPGRVRFVVPPG
EECCCEEEECCCCCEEEEEHHHCCCEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEECCC
MYRAGDYTVEGDWSSSSYFLAAGAAGQVPVTVRGLRRDSLQGDRAMLDILRRMGAGVAWD
CEECCCEEEECCCCCCCEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEEC
GDAVTVSPAPLKGIAVDMGHCPDLVPTVATVAAFASGDTTISNVGHLRIKECDRLASPAA
CCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEECCCCCEEHHHHHHHCCCHH
ELARAGVQCEVRDDGLVVHGAGRENIRIAPGTVFSTYADHRMAMSMAVLEMAGQPVTVDD
HHHHCCCEEEEECCCEEEECCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHCCCCEECCC
PACVGKSFPAFWEQWKKVSPCV
HHHCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA