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The map label for this gene is trpD

Identifier: 78358521

GI number: 78358521

Start: 3442419

End: 3443414

Strand: Reverse

Name: trpD

Synonym: Dde_3482

Alternate gene names: 78358521

Gene position: 3443414-3442419 (Counterclockwise)

Preceding gene: 78358522

Following gene: 78358520

Centisome position: 92.31

GC content: 63.86

Gene sequence:

>996_bases
ATGCATACTGCAGAAATACTGGAAACACTGGCTTCGGGCGGCGTGCTGCCGCCCGAAACGGCACACATGGCGTTTGACAG
ACTCATGTCCGGCGAGATGACTCCGGCGCAGGCGGGCAGCTTTCTTATGGGGCTGCGCAGCCACGGAGAAACGCCGGAAC
TGGTGGCCAGCGCGGTGCGTGCGGCGCTGGCGCATGCACGGCTCATACAGGGGCTTGAATATGACCGCATAGACATAGTG
GGCACGGGCGGAGACGGACGCAACAGTTTCAACTGCTCCACCGCCGCGGCGCTGACTTTGGCAGGCATGGGGTACAAGGT
GGTCAAGCACGGCAACAGGGCTGTTTCGTCCACCAGCGGCAGCGCCGATGTGGTGGAAGGTCTGGGACTGCCGCTGGAAA
CCGCGCCCGAAGATGTGCCGGTTTTGCTGGCACGGCATAACTTCGTGTTTCTGTTTGCCCCCTTTTATCATCCCGCTTTC
CGTCATGTGATGCCTGTACGCCGCGATCTGGGTATCCGTACGCTTTTCAACGTACTGGGCCCGCTGCTTAATCCCGCCCG
TCCCACCCGCATGCTGCTGGGTGTGGCAAAACCGGCCATGCTGCATACCATGGCCGACGCCCTGCTGCTGACAGGCGTGC
GGCGCGCGGCGGTGGTGCACGGTGCCGGCGGCTATGATGAGCTGACCACCATGGGGCCTGCCCGCGTGGTCATGGTGCGC
GACGGCGCCACGGAAGAGATGGAAATAAATCCGGCGGACCACGGATTTGCCCCGTGCACGCCCGCGCAGCTGGAAGTGCA
CGACAGGCAGGAGGCGCTGGAGGTCATGCGGCTGCTGCTGGCCGGAGAAGGCCCGGCTCCCATGCTTGACATGATGGCGT
TCAATGCGGGGCTGGCGGTGTATCTGATGGAGGATTCCATGCCTATTTCCGCAGCCATGGCCCGTGCGCGGCAGGCTGTT
GCCGGCGGCGCCGGCGGGAAGGTGCTGGATGCTTAG

Upstream 100 bases:

>100_bases
GTCCGTTCTGACCCCGCAGGGTGAAACCCTGTTGCAAAACTTCTGCCGCATGGCGACTGCCTGCACGGCCGGGGCCGTGT
GAATACGAGGTAAAAAGACA

Downstream 100 bases:

>100_bases
CCGTTTTGCCGCAGCAAAGGAGGCCGAAATTGCAGTGCTGTGCGCCCGGGAACGGGCCGGTACGCTGCCGCAGGCGTACC
GGGGTGCCCGTCCGGTGTTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MHTAEILETLASGGVLPPETAHMAFDRLMSGEMTPAQAGSFLMGLRSHGETPELVASAVRAALAHARLIQGLEYDRIDIV
GTGGDGRNSFNCSTAAALTLAGMGYKVVKHGNRAVSSTSGSADVVEGLGLPLETAPEDVPVLLARHNFVFLFAPFYHPAF
RHVMPVRRDLGIRTLFNVLGPLLNPARPTRMLLGVAKPAMLHTMADALLLTGVRRAAVVHGAGGYDELTTMGPARVVMVR
DGATEEMEINPADHGFAPCTPAQLEVHDRQEALEVMRLLLAGEGPAPMLDMMAFNAGLAVYLMEDSMPISAAMARARQAV
AGGAGGKVLDA

Sequences:

>Translated_331_residues
MHTAEILETLASGGVLPPETAHMAFDRLMSGEMTPAQAGSFLMGLRSHGETPELVASAVRAALAHARLIQGLEYDRIDIV
GTGGDGRNSFNCSTAAALTLAGMGYKVVKHGNRAVSSTSGSADVVEGLGLPLETAPEDVPVLLARHNFVFLFAPFYHPAF
RHVMPVRRDLGIRTLFNVLGPLLNPARPTRMLLGVAKPAMLHTMADALLLTGVRRAAVVHGAGGYDELTTMGPARVVMVR
DGATEEMEINPADHGFAPCTPAQLEVHDRQEALEVMRLLLAGEGPAPMLDMMAFNAGLAVYLMEDSMPISAAMARARQAV
AGGAGGKVLDA
>Mature_331_residues
MHTAEILETLASGGVLPPETAHMAFDRLMSGEMTPAQAGSFLMGLRSHGETPELVASAVRAALAHARLIQGLEYDRIDIV
GTGGDGRNSFNCSTAAALTLAGMGYKVVKHGNRAVSSTSGSADVVEGLGLPLETAPEDVPVLLARHNFVFLFAPFYHPAF
RHVMPVRRDLGIRTLFNVLGPLLNPARPTRMLLGVAKPAMLHTMADALLLTGVRRAAVVHGAGGYDELTTMGPARVVMVR
DGATEEMEINPADHGFAPCTPAQLEVHDRQEALEVMRLLLAGEGPAPMLDMMAFNAGLAVYLMEDSMPISAAMARARQAV
AGGAGGKVLDA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=279, Percent_Identity=41.5770609318996, Blast_Score=191, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6320561, Length=323, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_DESDG (Q30VM1)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_389970.1
- HSSP:   P66992
- ProteinModelPortal:   Q30VM1
- SMR:   Q30VM1
- STRING:   Q30VM1
- GeneID:   3758460
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_3482
- NMPDR:   fig|207559.3.peg.3690
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   CLSK704641
- BioCyc:   DDES207559:DDE_3482-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34907; Mature: 34907

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTAEILETLASGGVLPPETAHMAFDRLMSGEMTPAQAGSFLMGLRSHGETPELVASAVR
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AALAHARLIQGLEYDRIDIVGTGGDGRNSFNCSTAAALTLAGMGYKVVKHGNRAVSSTSG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCC
SADVVEGLGLPLETAPEDVPVLLARHNFVFLFAPFYHPAFRHVMPVRRDLGIRTLFNVLG
CHHHHHHCCCCCCCCCCCCCEEEEECCEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHH
PLLNPARPTRMLLGVAKPAMLHTMADALLLTGVRRAAVVHGAGGYDELTTMGPARVVMVR
HHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCCCEEEEEEE
DGATEEMEINPADHGFAPCTPAQLEVHDRQEALEVMRLLLAGEGPAPMLDMMAFNAGLAV
CCCCCCEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEE
YLMEDSMPISAAMARARQAVAGGAGGKVLDA
EEEECCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHTAEILETLASGGVLPPETAHMAFDRLMSGEMTPAQAGSFLMGLRSHGETPELVASAVR
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AALAHARLIQGLEYDRIDIVGTGGDGRNSFNCSTAAALTLAGMGYKVVKHGNRAVSSTSG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCC
SADVVEGLGLPLETAPEDVPVLLARHNFVFLFAPFYHPAFRHVMPVRRDLGIRTLFNVLG
CHHHHHHCCCCCCCCCCCCCEEEEECCEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHH
PLLNPARPTRMLLGVAKPAMLHTMADALLLTGVRRAAVVHGAGGYDELTTMGPARVVMVR
HHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCCCEEEEEEE
DGATEEMEINPADHGFAPCTPAQLEVHDRQEALEVMRLLLAGEGPAPMLDMMAFNAGLAV
CCCCCCEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEE
YLMEDSMPISAAMARARQAVAGGAGGKVLDA
EEEECCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA