Click here to switch to the map view.

The map label for this gene is bioD [H]

Identifier: 78357705

GI number: 78357705

Start: 2676019

End: 2676735

Strand: Direct

Name: bioD [H]

Synonym: Dde_2663

Alternate gene names: 78357705

Gene position: 2676019-2676735 (Clockwise)

Preceding gene: 78357704

Following gene: 78357708

Centisome position: 71.74

GC content: 60.39

Gene sequence:

>717_bases
ATGAATCATCGTGAACCGATGCCCCTGCACCTGTTTGTCACAGGAACGGACACCGGTGCGGGAAAAACCGTGGTCAGCCT
GCTGCTGCTTAAAGTTCTGCACGGGCGCGGGCACATGCCCCGTTACTTCAAACCGCTGCAGACCGGCTGTATTTCTCCCT
CGGATGCGGACAGTGACGCCCGTTTCATCCATAACTATCATGAGCCGCTGCGGAACATTGCGCCGGAACATTCCACGGGG
CTGTGCTTCAAGTCTCCCAAGGCTCCGCTCTATGCCGCGCGCGACGAAGGCCGCGGCATAGAGGCGGAAACCGTCTTGCG
CAGGCTGGCATCCCTGCGCAGGGAAAAGGCGCCCCTCGTGGCGGAAGGAGCAGGCGGGCTGCTGGTACCGGTAACCCCGC
ACGCCACCGTTATCGATATTATCGAACAGTCGGGCATGCGGCCCGTACTGGTGGCCCGCACGGGGCTGGGCACCATCAAC
CATACGCTCCTTTCACTGGAGGTGCTCAGGCTGCGGAACATAAAACCGGCAGGGATTGTGTTTGTCGAGGCAAGGGATGA
ACCCACGCCCGCAGCCATGATTCAGGAAAACATGGACGCCGTGTCCGCATTTTCCGGAATATCCGTCAGCGGCGTTGTGC
CGCATATTTCTGATTTTCATTCACCGCCCCGGCAGGCTCTGGCCGTCGTGGAGCGGCTTGTGGACGGGATGCTTTAG

Upstream 100 bases:

>100_bases
CACGAAGAGCCGTCATACGTCTGGGCATGACGGCTCTGCATTCGGCCCGCGACGTAGAGGTATGCGTGCGGAGCCTTACG
ACGATCCTGCGAGGTATTGT

Downstream 100 bases:

>100_bases
CCCCGTCCGCCTGCCACCCGCACAGACCCGCCGGTCTTTTCCGCATGCTCCGGAAAGCAGGCCAGCAGGTCGTCCAGAGT
TTCGCGGCGGCGGATAAGCC

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MNHREPMPLHLFVTGTDTGAGKTVVSLLLLKVLHGRGHMPRYFKPLQTGCISPSDADSDARFIHNYHEPLRNIAPEHSTG
LCFKSPKAPLYAARDEGRGIEAETVLRRLASLRREKAPLVAEGAGGLLVPVTPHATVIDIIEQSGMRPVLVARTGLGTIN
HTLLSLEVLRLRNIKPAGIVFVEARDEPTPAAMIQENMDAVSAFSGISVSGVVPHISDFHSPPRQALAVVERLVDGML

Sequences:

>Translated_238_residues
MNHREPMPLHLFVTGTDTGAGKTVVSLLLLKVLHGRGHMPRYFKPLQTGCISPSDADSDARFIHNYHEPLRNIAPEHSTG
LCFKSPKAPLYAARDEGRGIEAETVLRRLASLRREKAPLVAEGAGGLLVPVTPHATVIDIIEQSGMRPVLVARTGLGTIN
HTLLSLEVLRLRNIKPAGIVFVEARDEPTPAAMIQENMDAVSAFSGISVSGVVPHISDFHSPPRQALAVVERLVDGML
>Mature_238_residues
MNHREPMPLHLFVTGTDTGAGKTVVSLLLLKVLHGRGHMPRYFKPLQTGCISPSDADSDARFIHNYHEPLRNIAPEHSTG
LCFKSPKAPLYAARDEGRGIEAETVLRRLASLRREKAPLVAEGAGGLLVPVTPHATVIDIIEQSGMRPVLVARTGLGTIN
HTLLSLEVLRLRNIKPAGIVFVEARDEPTPAAMIQENMDAVSAFSGISVSGVVPHISDFHSPPRQALAVVERLVDGML

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=214, Percent_Identity=28.5046728971963, Blast_Score=79, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324385, Length=177, Percent_Identity=36.1581920903955, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25757; Mature: 25757

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHREPMPLHLFVTGTDTGAGKTVVSLLLLKVLHGRGHMPRYFKPLQTGCISPSDADSDA
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHH
RFIHNYHEPLRNIAPEHSTGLCFKSPKAPLYAARDEGRGIEAETVLRRLASLRREKAPLV
HHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCEE
AEGAGGLLVPVTPHATVIDIIEQSGMRPVLVARTGLGTINHTLLSLEVLRLRNIKPAGIV
EECCCCEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEE
FVEARDEPTPAAMIQENMDAVSAFSGISVSGVVPHISDFHSPPRQALAVVERLVDGML
EEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNHREPMPLHLFVTGTDTGAGKTVVSLLLLKVLHGRGHMPRYFKPLQTGCISPSDADSDA
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHH
RFIHNYHEPLRNIAPEHSTGLCFKSPKAPLYAARDEGRGIEAETVLRRLASLRREKAPLV
HHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCEE
AEGAGGLLVPVTPHATVIDIIEQSGMRPVLVARTGLGTINHTLLSLEVLRLRNIKPAGIV
EECCCCEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEE
FVEARDEPTPAAMIQENMDAVSAFSGISVSGVVPHISDFHSPPRQALAVVERLVDGML
EEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA