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The map label for this gene is gmhA [H]

Identifier: 78357661

GI number: 78357661

Start: 2634947

End: 2635789

Strand: Direct

Name: gmhA [H]

Synonym: Dde_2619

Alternate gene names: 78357661

Gene position: 2634947-2635789 (Clockwise)

Preceding gene: 78357653

Following gene: 78357662

Centisome position: 70.64

GC content: 58.48

Gene sequence:

>843_bases
ATGCGCCCGCCGGACAAGAATAAAAGCCCGCACCGGCCGCGGCACAGGTGCAAACACCCGCCGACGGCAAAGACAGACTC
ATGCAACATCAATAATACCGGATTGATACATAACAATGCCACGAAACATTGCGAGCCTGCGCCATTTAGGGTAGTCCCAA
GTGGTTCCGTTTCGCCCCTTGCGTTTCGCGGAATGTTTCAACAAGGAGCCCCGATGTCAGACACTGCCAAAATAATGGTC
ATGGAGCACGCGCTGGACGGCAGCCGCCTGCGGGAAGCGTTTTTTCAGGAAAACGCCGACGCCGTGGTGGATGTGGCGCG
TATCATGGCCGTATGCATCGCGCGCGGCGGCAAGGTGCTGCTGTGCGGCAACGGCGGCAGCGCGGCCGATGCGCAACATC
TGGCCGCCGAATTCGTGAACAGATTTATTATGGACAGACCCCCGCTGCCTGCCATCGCCCTGACCACCGATTCCTCCGTG
CTCACATCCATCGGCAATGATTTCGGATTTGAGCAGGTTTTCAGCAAACAGGTGCAGGCGCTGGGCCAGCAGGGCGATGT
GCTTATAGCCATATCCACTTCGGGCGGCAGTCCCAACGTGCTTGCAGCACTGCGGGCCGCTGCCGAAAAAGGCGTCATCA
CCGTGGGGCTGACCGGCAAAGGCGGCGGCGCCATGGCCGAACTGTGTGATTACCTCATCGACGTGAAAGACAGCCGCACA
CCGCTCATTCAGGAAATACACATAGCCGTAGGACACCTGCTGTGCGGTCTGGTGGACCATTATCTTTTTGAAAACGTGCT
TGAACTGCAGCCCTGGCTTGAACAGCCGGCGGAAAGCCGCTAG

Upstream 100 bases:

>100_bases
CTATAAAAACTCTTTTCAATTCGCGATGCATGACTATCCCTAGTAGAAAGCACAGATTCCATCAAGAAGCCGTAAGGCTT
TGCGGCAGGGACTACCCCAC

Downstream 100 bases:

>100_bases
GCGGGGCTTGCCATATATCCGTTAAGTTTCAGCAAAGAGGAATACCATGCCCATTTACGAGTACACATGCAAAGCCTGTC
ACAAGGACTTTGAAGAACTG

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRPPDKNKSPHRPRHRCKHPPTAKTDSCNINNTGLIHNNATKHCEPAPFRVVPSGSVSPLAFRGMFQQGAPMSDTAKIMV
MEHALDGSRLREAFFQENADAVVDVARIMAVCIARGGKVLLCGNGGSAADAQHLAAEFVNRFIMDRPPLPAIALTTDSSV
LTSIGNDFGFEQVFSKQVQALGQQGDVLIAISTSGGSPNVLAALRAAAEKGVITVGLTGKGGGAMAELCDYLIDVKDSRT
PLIQEIHIAVGHLLCGLVDHYLFENVLELQPWLEQPAESR

Sequences:

>Translated_280_residues
MRPPDKNKSPHRPRHRCKHPPTAKTDSCNINNTGLIHNNATKHCEPAPFRVVPSGSVSPLAFRGMFQQGAPMSDTAKIMV
MEHALDGSRLREAFFQENADAVVDVARIMAVCIARGGKVLLCGNGGSAADAQHLAAEFVNRFIMDRPPLPAIALTTDSSV
LTSIGNDFGFEQVFSKQVQALGQQGDVLIAISTSGGSPNVLAALRAAAEKGVITVGLTGKGGGAMAELCDYLIDVKDSRT
PLIQEIHIAVGHLLCGLVDHYLFENVLELQPWLEQPAESR
>Mature_280_residues
MRPPDKNKSPHRPRHRCKHPPTAKTDSCNINNTGLIHNNATKHCEPAPFRVVPSGSVSPLAFRGMFQQGAPMSDTAKIMV
MEHALDGSRLREAFFQENADAVVDVARIMAVCIARGGKVLLCGNGGSAADAQHLAAEFVNRFIMDRPPLPAIALTTDSSV
LTSIGNDFGFEQVFSKQVQALGQQGDVLIAISTSGGSPNVLAALRAAAEKGVITVGLTGKGGGAMAELCDYLIDVKDSRT
PLIQEIHIAVGHLLCGLVDHYLFENVLELQPWLEQPAESR

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=167, Percent_Identity=46.7065868263473, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786416, Length=169, Percent_Identity=47.3372781065089, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 29980; Mature: 29980

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPDKNKSPHRPRHRCKHPPTAKTDSCNINNTGLIHNNATKHCEPAPFRVVPSGSVSPL
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCHH
AFRGMFQQGAPMSDTAKIMVMEHALDGSRLREAFFQENADAVVDVARIMAVCIARGGKVL
HHHHHHHCCCCCCCCCEEEEEEHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEE
LCGNGGSAADAQHLAAEFVNRFIMDRPPLPAIALTTDSSVLTSIGNDFGFEQVFSKQVQA
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHH
LGQQGDVLIAISTSGGSPNVLAALRAAAEKGVITVGLTGKGGGAMAELCDYLIDVKDSRT
HCCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCCCC
PLIQEIHIAVGHLLCGLVDHYLFENVLELQPWLEQPAESR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRPPDKNKSPHRPRHRCKHPPTAKTDSCNINNTGLIHNNATKHCEPAPFRVVPSGSVSPL
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCHH
AFRGMFQQGAPMSDTAKIMVMEHALDGSRLREAFFQENADAVVDVARIMAVCIARGGKVL
HHHHHHHCCCCCCCCCEEEEEEHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEE
LCGNGGSAADAQHLAAEFVNRFIMDRPPLPAIALTTDSSVLTSIGNDFGFEQVFSKQVQA
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHH
LGQQGDVLIAISTSGGSPNVLAALRAAAEKGVITVGLTGKGGGAMAELCDYLIDVKDSRT
HCCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCCCC
PLIQEIHIAVGHLLCGLVDHYLFENVLELQPWLEQPAESR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA