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The map label for this gene is appB [H]

Identifier: 78357635

GI number: 78357635

Start: 2610813

End: 2611844

Strand: Direct

Name: appB [H]

Synonym: Dde_2593

Alternate gene names: 78357635

Gene position: 2610813-2611844 (Clockwise)

Preceding gene: 78357634

Following gene: 78357636

Centisome position: 69.99

GC content: 59.59

Gene sequence:

>1032_bases
GTGAACGCGGCAACGGCAGAAGCAGCGGGACGGAAGGCTGCCGGACTGGCCGTACGGGCAGGCAGACGTCTTTTATGGGT
TATGGCGGTGTTCTGGGGCATTACGCTTATCAGCTTTGCCGTCATACATCTGGCGCCGGGGTCGCCCACCGACCTGCAGA
CAACTCTGAACCCGCAGGCCGGAGCCGACGCCCGCATGCGGCTGGAAAAGCTGTACGGGCTGGACCAGCCGCTGCATGTG
CAATACGGGCAATGGGTTAACCGGCTAATCCGGCTTGACTTCGGCATGTCCATGTCCGGAGACATGCGGCCCGTATGGGA
CAAAATCAGCGAGCGACTTCCGCTGACCGTGGGGATGAACCTTGCCTCCATGCTGCTAACGCTGCTCATTGCCCTGCCTG
TCGGCATTGCTTCGGCTTACTGGCAGGGGCGCTGGTTTGACCGCGCCAGCACCGTGCTTGTATTCATAGGCTTTGCCATG
CCGGGATTCTGGCTTGCGCTGCTTATGATGCTGCTGTTCGGCATTCATCTCGGCTGGCTGCCCATTTCCGGCATAACGTC
TCTTGATTACGCCCAGCTGAGCACCACGGGCAAAATACTTGATGTGGCAGCGCACCTTGCCATGCCGCTGTTTATCTATA
CGTTCGGAAGCCTTGCCGGCATGTCACGCTTTATGCGTTCTTCCATGCTGGAGGTGCTCCGGCAGGATTACATACTGACA
GCCCGCGCCAAAGGGCTGGGGCTGGGCACGGTGATTTTCCGCCATGCACTGCGCAACGCCCTGCTTCCGGTCATAACCAT
TCTGGGGCTTTCTGTACCCGGCCTTATAGGCGGCAGCGTGATCATAGAATCCATTTTTGCCCTGCCCGGTCTGGGGCAGC
TTTTCTACGGTGCCGTCATGGCCCGTGATTATCCGCTTATTATGGGAAACCTTGTTCTGGGTGCGGTGCTTACTCTGGCA
GGCAACCTGCTGGCGGACGTCTGCTACGGACTGGCCGACCCGCGTATCCGCTCTGCACGGGAGGCTCGCTGA

Upstream 100 bases:

>100_bases
TGAAGTGTACAGGCAGTTTCTTACGGTACGTCTGGCTCCCGCCGACTGGCAGGAAGAAGTCAAAGCTCTGCGCAACTGGC
TTGCAGCCGGAGACTAGGCA

Downstream 100 bases:

>100_bases
CATGGCCGGTTTATTTCCCCTGCGCGTGGGTCTTTTCTTTCGCAAAGCAGCAGGACGTTACGGCATGCTGTGGACCGGCG
CAGCCATAGTTGGCAGCATG

Product: oligopeptide ABC transporter permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNAATAEAAGRKAAGLAVRAGRRLLWVMAVFWGITLISFAVIHLAPGSPTDLQTTLNPQAGADARMRLEKLYGLDQPLHV
QYGQWVNRLIRLDFGMSMSGDMRPVWDKISERLPLTVGMNLASMLLTLLIALPVGIASAYWQGRWFDRASTVLVFIGFAM
PGFWLALLMMLLFGIHLGWLPISGITSLDYAQLSTTGKILDVAAHLAMPLFIYTFGSLAGMSRFMRSSMLEVLRQDYILT
ARAKGLGLGTVIFRHALRNALLPVITILGLSVPGLIGGSVIIESIFALPGLGQLFYGAVMARDYPLIMGNLVLGAVLTLA
GNLLADVCYGLADPRIRSAREAR

Sequences:

>Translated_343_residues
MNAATAEAAGRKAAGLAVRAGRRLLWVMAVFWGITLISFAVIHLAPGSPTDLQTTLNPQAGADARMRLEKLYGLDQPLHV
QYGQWVNRLIRLDFGMSMSGDMRPVWDKISERLPLTVGMNLASMLLTLLIALPVGIASAYWQGRWFDRASTVLVFIGFAM
PGFWLALLMMLLFGIHLGWLPISGITSLDYAQLSTTGKILDVAAHLAMPLFIYTFGSLAGMSRFMRSSMLEVLRQDYILT
ARAKGLGLGTVIFRHALRNALLPVITILGLSVPGLIGGSVIIESIFALPGLGQLFYGAVMARDYPLIMGNLVLGAVLTLA
GNLLADVCYGLADPRIRSAREAR
>Mature_343_residues
MNAATAEAAGRKAAGLAVRAGRRLLWVMAVFWGITLISFAVIHLAPGSPTDLQTTLNPQAGADARMRLEKLYGLDQPLHV
QYGQWVNRLIRLDFGMSMSGDMRPVWDKISERLPLTVGMNLASMLLTLLIALPVGIASAYWQGRWFDRASTVLVFIGFAM
PGFWLALLMMLLFGIHLGWLPISGITSLDYAQLSTTGKILDVAAHLAMPLFIYTFGSLAGMSRFMRSSMLEVLRQDYILT
ARAKGLGLGTVIFRHALRNALLPVITILGLSVPGLIGGSVIIESIFALPGLGQLFYGAVMARDYPLIMGNLVLGAVLTLA
GNLLADVCYGLADPRIRSAREAR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=36.3905325443787, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1787053, Length=316, Percent_Identity=34.8101265822785, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1789888, Length=323, Percent_Identity=35.9133126934984, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1788504, Length=354, Percent_Identity=31.3559322033898, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1787497, Length=316, Percent_Identity=34.1772151898734, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787761, Length=320, Percent_Identity=36.5625, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=31.203007518797, Blast_Score=140, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37216; Mature: 37216

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAATAEAAGRKAAGLAVRAGRRLLWVMAVFWGITLISFAVIHLAPGSPTDLQTTLNPQA
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCC
GADARMRLEKLYGLDQPLHVQYGQWVNRLIRLDFGMSMSGDMRPVWDKISERLPLTVGMN
CCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCC
LASMLLTLLIALPVGIASAYWQGRWFDRASTVLVFIGFAMPGFWLALLMMLLFGIHLGWL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PISGITSLDYAQLSTTGKILDVAAHLAMPLFIYTFGSLAGMSRFMRSSMLEVLRQDYILT
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ARAKGLGLGTVIFRHALRNALLPVITILGLSVPGLIGGSVIIESIFALPGLGQLFYGAVM
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
ARDYPLIMGNLVLGAVLTLAGNLLADVCYGLADPRIRSAREAR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure
MNAATAEAAGRKAAGLAVRAGRRLLWVMAVFWGITLISFAVIHLAPGSPTDLQTTLNPQA
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCC
GADARMRLEKLYGLDQPLHVQYGQWVNRLIRLDFGMSMSGDMRPVWDKISERLPLTVGMN
CCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCC
LASMLLTLLIALPVGIASAYWQGRWFDRASTVLVFIGFAMPGFWLALLMMLLFGIHLGWL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PISGITSLDYAQLSTTGKILDVAAHLAMPLFIYTFGSLAGMSRFMRSSMLEVLRQDYILT
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ARAKGLGLGTVIFRHALRNALLPVITILGLSVPGLIGGSVIIESIFALPGLGQLFYGAVM
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
ARDYPLIMGNLVLGAVLTLAGNLLADVCYGLADPRIRSAREAR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]