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The map label for this gene is appC [H]

Identifier: 78357636

GI number: 78357636

Start: 2611846

End: 2612703

Strand: Direct

Name: appC [H]

Synonym: Dde_2594

Alternate gene names: 78357636

Gene position: 2611846-2612703 (Clockwise)

Preceding gene: 78357635

Following gene: 78357638

Centisome position: 70.02

GC content: 59.32

Gene sequence:

>858_bases
ATGGCCGGTTTATTTCCCCTGCGCGTGGGTCTTTTCTTTCGCAAAGCAGCAGGACGTTACGGCATGCTGTGGACCGGCGC
AGCCATAGTTGGCAGCATGTCCGTACTGGCGCTGCTGGCACCGTGGATAGCACCCTATGACCCCACGCTTCTCAATGTTC
ATGCCATACTGCAACCGCCCAGCACGGTGCACCCTTTCGGAACAGATGCACTGGGGCGCGACATTTTTTCGCGCATGCTG
TACGGCGCGCGGGTATCTCTCTGGGTAGGGTTTGTGGCGGTAGGCATTGCCGCGGCCATCGGCACTGTTCTGGGGCTGGT
GGCAGGCTATTTCCGCGGACTGACCGATGAAATCATCATGCGCTTTGTCGATGTGATGCTCTGCTTTCCTTCATTTTTTC
TCATCCTCGCGGTCATTGCCTTTCTGGAACCGAGCCTTGGCAATATAATGATCGTCATCGGCCTGACATCGTGGATGGGA
GTGGCCCGACTGGTGCGTGCCGAAACGCTGACCCTGCGGGAGCGGGATTTCATTGCGGCATCACGCCTTGCCGGTGCAGG
TACGGTCCGCATTCTTTTTATGCACATTCTGCCCAACGCCATCGCGCCGGTGCTGGTGGCCGCCACACTGGGCGTGGCCG
GCGCCATACTGACGGAAAGCGCCCTGAGCTTTCTCGGGCTGGGAGTTCAGCCGCCCATGCCCAGCTGGGGCAACATGCTG
ATGGAAGGCAAAGACGTGATGGAATTTGCTCCGTGGCAGTCTCTCTTTCCCGGTGCGGCCATACTGATCACCGTTCTGGG
GTACAACCTGTTGGGAGAAAGCCTGCGCGACATTCTGGATCCGCGGCTGCGCCGCTGA

Upstream 100 bases:

>100_bases
GTTCTGGGTGCGGTGCTTACTCTGGCAGGCAACCTGCTGGCGGACGTCTGCTACGGACTGGCCGACCCGCGTATCCGCTC
TGCACGGGAGGCTCGCTGAC

Downstream 100 bases:

>100_bases
CTCCGCACCGGTCACCGCAAGCCTTTCCCGCGTTGTTATGCGGCATTACCTCTTGCCGCCCTATACTCTTGAGGGTAGAT
ACGGTAAAAAAAGTTTTCGC

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MAGLFPLRVGLFFRKAAGRYGMLWTGAAIVGSMSVLALLAPWIAPYDPTLLNVHAILQPPSTVHPFGTDALGRDIFSRML
YGARVSLWVGFVAVGIAAAIGTVLGLVAGYFRGLTDEIIMRFVDVMLCFPSFFLILAVIAFLEPSLGNIMIVIGLTSWMG
VARLVRAETLTLRERDFIAASRLAGAGTVRILFMHILPNAIAPVLVAATLGVAGAILTESALSFLGLGVQPPMPSWGNML
MEGKDVMEFAPWQSLFPGAAILITVLGYNLLGESLRDILDPRLRR

Sequences:

>Translated_285_residues
MAGLFPLRVGLFFRKAAGRYGMLWTGAAIVGSMSVLALLAPWIAPYDPTLLNVHAILQPPSTVHPFGTDALGRDIFSRML
YGARVSLWVGFVAVGIAAAIGTVLGLVAGYFRGLTDEIIMRFVDVMLCFPSFFLILAVIAFLEPSLGNIMIVIGLTSWMG
VARLVRAETLTLRERDFIAASRLAGAGTVRILFMHILPNAIAPVLVAATLGVAGAILTESALSFLGLGVQPPMPSWGNML
MEGKDVMEFAPWQSLFPGAAILITVLGYNLLGESLRDILDPRLRR
>Mature_284_residues
AGLFPLRVGLFFRKAAGRYGMLWTGAAIVGSMSVLALLAPWIAPYDPTLLNVHAILQPPSTVHPFGTDALGRDIFSRMLY
GARVSLWVGFVAVGIAAAIGTVLGLVAGYFRGLTDEIIMRFVDVMLCFPSFFLILAVIAFLEPSLGNIMIVIGLTSWMGV
ARLVRAETLTLRERDFIAASRLAGAGTVRILFMHILPNAIAPVLVAATLGVAGAILTESALSFLGLGVQPPMPSWGNMLM
EGKDVMEFAPWQSLFPGAAILITVLGYNLLGESLRDILDPRLRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=267, Percent_Identity=45.6928838951311, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1789964, Length=259, Percent_Identity=48.2625482625483, Blast_Score=210, Evalue=9e-56,
Organism=Escherichia coli, GI1787760, Length=258, Percent_Identity=41.4728682170543, Blast_Score=207, Evalue=4e-55,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=39.344262295082, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1787498, Length=265, Percent_Identity=39.2452830188679, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787549, Length=252, Percent_Identity=38.0952380952381, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1788505, Length=227, Percent_Identity=33.920704845815, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30642; Mature: 30511

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHCC
>Mature Secondary Structure 
AGLFPLRVGLFFRKAAGRYGMLWTGAAIVGSMSVLALLAPWIAPYDPTLLNVHAILQPP
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHEEECCC
STVHPFGTDALGRDIFSRMLYGARVSLWVGFVAVGIAAAIGTVLGLVAGYFRGLTDEIIM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RFVDVMLCFPSFFLILAVIAFLEPSLGNIMIVIGLTSWMGVARLVRAETLTLRERDFIAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLAGAGTVRILFMHILPNAIAPVLVAATLGVAGAILTESALSFLGLGVQPPMPSWGNML
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MEGKDVMEFAPWQSLFPGAAILITVLGYNLLGESLRDILDPRLRR
HCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]